Effects of ADAM10 deletion on Notch-1 signaling pathway and neuronal maintenance in adult mouse brain

Gene

Volumn 555, Issue 2, 2015, Pages 150-158

  Zhuang, Jianlong ^a,b   Wei, Qiulan ^a   Lin, Zhaohua ^a   Zhou, Changwen ^a  

^a FUJIAN MEDICAL UNIVERSITY   (China)

^b Prenatal Diagnosis Center Quanzhou Women and Children's Hospital   (China)

Author keywords

ADAM10; Conditional knockout; Hippocampal dentate gyrus; Neuronal maintenance; Notch 1 signaling

Indexed keywords

ADAM10 ENDOPEPTIDASE; NOTCH1 RECEPTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR HES 1; TRANSCRIPTION FACTOR HES 5; TRANSCRIPTION FACTOR HEY 1; TRANSCRIPTION FACTOR HEY 2; UNCLASSIFIED DRUG; ADAM PROTEIN; ADAM10 PROTEIN, MOUSE; MEMBRANE PROTEIN; NOTCH1 PROTEIN, MOUSE; SECRETASE;

ADULT; ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN NERVE CELL; CONTROLLED STUDY; DENTATE GYRUS; GENE INACTIVATION; GENOTYPE; HIPPOCAMPUS; LEARNING DISORDER; MALE; MOUSE; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NONHUMAN; SIGNAL TRANSDUCTION; SPATIAL LEARNING; SPATIAL MEMORY; TRANSGENE; ANIMAL; BRAIN; C57BL MOUSE; CELL DIFFERENTIATION; CELL PROLIFERATION; GENE DELETION; GENE EXPRESSION REGULATION; GENETICS; KNOCKOUT MOUSE; MAZE TEST; MEMORY; METABOLISM; NERVE CELL; PHYSIOLOGY;

MUS;

ADAM PROTEINS; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; BRAIN; CELL DIFFERENTIATION; CELL PROLIFERATION; DENTATE GYRUS; GENE DELETION; GENE EXPRESSION REGULATION; HIPPOCAMPUS; MALE; MAZE LEARNING; MEMBRANE PROTEINS; MEMORY; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEUROGENESIS; NEURONS; RECEPTOR, NOTCH1; SIGNAL TRANSDUCTION; SPATIAL LEARNING;

EID: 84920467586     PISSN: 03781119     EISSN: 18790038     Source Type: Journal    
DOI: 10.1016/j.gene.2014.10.056     Document Type: Article

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