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Journal of Thrombosis and Haemostasis

Volumn 12, Issue 11, 2014, Pages 1898-1905

Competitive mode and site of interaction of ticagrelor at the human platelet P2Y12-receptor

(6) Hoffmann, K a Lutz, D A a Strassburger J a Baqi, Y a,b Muller C E a von Kugelgen I a

a UNIVERSITY OF BONN (Germany)

b SULTAN QABOOS UNIVERSITY (Oman)

Author keywords

Binding site; Mode of action; Platelets; Receptors, purinergic P2Y12

Indexed keywords

ADENOSINE; ADENOSINE DIPHOSPHATE; ANTITHROMBOCYTIC AGENT; CYCLIC AMP; FORSKOLIN; LUCIFERASE; METHYLTHIO-ADP; NUCLEOTIDE; P2RY12 PROTEIN, HUMAN; PROTEIN BINDING; PURINERGIC P2Y RECEPTOR AGONIST; PURINERGIC P2Y RECEPTOR ANTAGONIST; PURINERGIC P2Y12 RECEPTOR; TICAGRELOR;

ANALOGS AND DERIVATIVES; ANIMAL; BINDING COMPETITION; BINDING SITE; CHO CELL LINE; CRICETULUS; DNA RESPONSIVE ELEMENT; DOSE RESPONSE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; HUMAN; METABOLISM; MUTATION; REPORTER GENE;

ADENOSINE; ADENOSINE DIPHOSPHATE; ANIMALS; BINDING SITES; BINDING, COMPETITIVE; CHO CELLS; COLFORSIN; CRICETULUS; CYCLIC AMP; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; GENES, REPORTER; HUMANS; LUCIFERASES; MUTATION; PLATELET AGGREGATION INHIBITORS; PROTEIN BINDING; PURINERGIC P2Y RECEPTOR AGONISTS; PURINERGIC P2Y RECEPTOR ANTAGONISTS; RECEPTORS, PURINERGIC P2Y12; RESPONSE ELEMENTS; THIONUCLEOTIDES; TRANSFECTION;

EID: 84920288728 PISSN: 15387933 EISSN: 15387836 Source Type: Journal
DOI: 10.1111/jth.12719 Document Type: Article

Times cited : (39)

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