ETV6 (TEL1) regulates embryonic hematopoiesis in zebrafish

Haematologica

Volumn 100, Issue 1, 2015, Pages 23-31

  Rasighaemi, Parisa ^a   Onnebo, Sara M N ^a   Liongue, Clifford ^a   Ward, Alister C ^a  

^a DEAKIN UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; MORPHOLINO OLIGONUCLEOTIDE; ZEBRAFISH PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD CELL; BLOOD SMEAR; BONE MARROW CELL; CONTROLLED STUDY; DNA SEQUENCE; EMBRYO; EMBRYO DEVELOPMENT; ERYTHROCYTE; EXON; GENE; GENE EXPRESSION; GENE SILENCING; HEMATOPOIESIS; HETEROPHIL; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LYMPHOPOIESIS; MACROPHAGE; MESODERM; NONHUMAN; ORTHOLOGY; PHENOTYPE; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; STEM CELL; STOP CODON; TRANSCRIPTION FACTOR ETV6 GENE; ZEBRA FISH; ANIMAL; ANIMAL EMBRYO; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CELL DIFFERENTIATION; CELL LINEAGE; CYTOLOGY; EMBRYOLOGY; ENZYME IMMUNOASSAY; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; PHYSIOLOGY;

ANIMALS; CELL DIFFERENTIATION; CELL LINEAGE; CELLS, CULTURED; EMBRYO, NONMAMMALIAN; EMBRYONIC DEVELOPMENT; ERYTHROCYTES; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEMATOPOIESIS; HUMANS; IMMUNOENZYME TECHNIQUES; MACROPHAGES; MESODERM; MORPHOLINOS; MYELOID CELLS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 84920120559     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2014.104091     Document Type: Article

References (50)

1. Oikawa T, Yamada T. Molecular biology of the Ets family of transcription factors. Gene. 2003;303(1):11-34.
2. Wang LC, Kuo A, Fujiwara Y, Gilliland DG, Golub TR, Orkin SH. Yolk sac angiogenic defects and intra-embryonic apoptosis in mice lacking the Ets-related factor TEL. EMBO J. 1997;16(14):4374-83.
3. Golub TR, McLean T, Stegmaier K, Carroll M, Tomasson M, Gilliland DG. The TEL gene and human leukemia. Biochim Biophys Acta. 1996;1288(1):M7-10.
4. Chakrabarti SR, Nucifora G. The leukemia associated gene TEL encodes a transcription repressor which associates with SMRT and mSin3A. Biochem Biophys Res Commun. 1999;264(3):871-7.
5. Kim CA, Phillips ML, Kim W, Gingery M, Tran HH, Robinson MA, et al. Polymerization of the SAM domain of TEL in leukemogenesis and transcriptional repression. EMBO J. 2001;20(15):4173-82.
6. Potter MD, Buijs A, Kreider B, van Rompaey L, Grosveld GC. Identification and characterization of a new human ETS-family transcription factor, TEL2, that is expressed in hematopoietic tissue and can associate with TEL1/ETV 6. Blood. 2000;95(11):3341-8.
7. Wood LD, Irvin BJ, Nucifora G, Luce KS, Hiebert SW. Small ubiquitin-like modifier conjugation regulates nuclear export of TEL, a putative tumor suppressor. Proc Natl Acad Sci USA. 2003;100(6):3257-62.
8. Poirel H, Oury C, Carron C, Duprez E, Laabi Y, Tsapis A, et al. The TEL gene products: nuclear phosphoproteins with DNA binding properties. Oncogene. 1997; 14(3):349-57.
9. Guidez F, Petrie K, Ford AM, Lu H, Bennett CM, MacGregor A, et al. Recruitment of the nuclear receptor corepressor N-CoR by TEL moiety of the childhood leukemia-associated TEL-AML1 oncoprotein. Blood. 2000;96(7):2557-60.
10. Wang L, Hiebert SW. TEL contacts multiple co-repressors and specifically associates with histone deacetylase-3. Oncogene. 2001;20(28):3716-25.
11. De Braekeleer E, Douet-Guilbert N, Morel F, Le Bris M-J, Basinko A, De Braekeleer M. ETV6 fusion genes in hematological malignancies: A review. Leuk Res. 2012;36(8): 945-61.
12. Peeters P, Raynaud SD, Cools J, Wlodarska I, Grosgeorge J, Philip P, et al. Fusion of TEL, the ETS-variant gene 6 (ETV6), to the receptor-associated kinase JAK2 as a result of t(9;12) in a lymphoid and t(9;15;12) in a myeloid leukemia. Blood. 1997;90(7): 2535-40.
13. Golub TR, Barker GF, Bohlander SK, Hiebert SW, Ward DC, Bray-Ward P, et al. Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia. Proc Natl Acad Sci USA. 1995; 92(11):4917-21.
14. Buijs A, Sherr S, van Baal S, van Bezouw S, van der Plas D, van Kessel GA, et al. Translocation (12; 22)(p13; q11) in myeloproliferative disorders results in fusion of the ETS-like TEL gene on 12p13 to the MN1 gene on 22q11. Oncogene. 1995; 10(8):1511-9.
15. Patel N, Goff LK, Clark T, Ford AM, Foot N, Lillington D, et al. Expression profile of wildtype ETV6 in childhood acute leukaemia. Br J Haematol. 2003;122(1):94-8.
16. Raynaud S, Cave H, Baens M, Bastard C, Cacheux V, Grosgeorge J, et al. The 12;21 translocation involving TEL and deletion of the other TEL allele: two frequently associated alterations found in childhood acute lymphoblastic leukemia. Blood. 1996;87(7): 2891-9.
17. Barjesteh van Waalwijk, van Doorn-Khosravani S, Spensberger D, de Knegt Y, Tang M, Lowenberg B, Delwel R. Somatic heterozygous mutations in ETV6 (TEL) and frequent absence of ETV6 protein in acute myeloid leukemia. Oncogene. 2005; 24(25):4129-37.
18. Wang LC, Swat W, Fujiwara Y, Davidson L, Visvader J, Kuo F, et al. The TEL/ETV6 gene is required specifically for hematopoiesis in the bone marrow. Genes Dev. 1998; 12(15):2392-402.
19. Ciau-Uitz A, Pinheiro P, Gupta R, Enver T, Patient R. Tel1/ETV6 specifies blood stem cells through the agency of VEGF signaling. Dev Cell. 2010;18(4):569-78.
20. Hock H, Meade E, Medeiros S, Schindler JW, Valk PJ, Fujiwara Y, et al. Tel/Etv6 is an essential and selective regulator of adult hematopoietic stem cell survival. Genes Dev. 2004;18(19):2336-41.
21. Eguchi-Ishimae M, Eguchi M, Maki K, Porcher C, Shimizu R, Yamamoto M, et al. Leukemia-related transcription factor TEL/ETV6 expands erythroid precursors and stimulates hemoglobin synthesis. Cancer Sci. 2009;100(4):689-97.
22. Davidson AJ, Zon LI. The 'definitive' (and 'primitive') guide to zebrafish hematopoiesis. Oncogene. 2004; 23(43): 7233-46.
23. Patterson LJ, Gering M, Eckfeldt CE, Green AR, Verfaillie CM, Ekker SC, et al. The transcription factors Scl and Lmo2 act together during development of the hemangioblast in zebrafish. Blood. 2007;109(6):2389-98.
24. Willett CE, Kawasaki H, Amemiya CT, Lin S, Steiner LA. Ikaros expression as a marker for lymphoid progenitors during zebrafish development. Dev Dyn. 2001;222(4):694-8.
25. Lieschke GJ, Oates AC, Paw BH, Thompson MA, Hall NE, Ward AC, et al. Zebrafish SPI- 1(PU.1) marks a site of myeloid development independent of primitive erythropoiesis: implications for axial patterning. Dev Biol. 2002;246(2):274-95.
26. Long Q, Meng A, Wang H, Jessen JR, Farrell MJ, Lin S. GATA-1 expression pattern can be recapitulated in living transgenic zebrafish using GFP reporter gene. Development. 1997;124(20):4105-11.
27. Liu F, Wen Z. Cloning and expression pattern of the lysozyme C gene in zebrafish. Mech Dev. 2002;113(1):69-72.
28. Brownlie A, Hersey C, Oates AC, Paw BH, Falick AM, Witkowska HE, et al. Characterization of embryonic globin genes of the zebrafish. Dev Biol. 2003;255(1):48-61.
29. Lieschke GJ, Oates AC, Crowhurst MO, Ward AC, Layton JE. Morphologic and functional characterization of granulocytes and macrophages in embryonic and adult zebrafish. Blood. 2001;98(10):3087-96.
30. Yoong S, O'Connell B, Soanes A, Crowhurst MO, Lieschke GJ, Ward AC. Characterization of the zebrafish matrix metalloproteinase 9 gene and its developmental expression pattern. Gene Expr Patterns. 2007;7(1-2):39-46.
31. Murayama E, Kissa K, Zapata A, Mordelet E, Briolat V, Lin H-F, et al. Tracing hematopoietic precursor migration to successive hematopoietic organs during zebrafish development. Immunity. 2006;25(6):963-75.
32. Willett CE, Cherry JJ, Steiner L. Characterization and expression of the recombination activating genes (rag1 and rag2) of zebrafish. Immunogenetics. 1997;45(6):394-404.
33. Onnebo SMN, Condron MM, McPhee DO, Lieschke GJ, Ward AC. Hematopoietic perturbation in zebrafish expressing a tel-jak2a fusion. Exp Hematol. 2005;33(2):182-8.
34. Onnebo SM, Rasighaemi P, Kumar J, Liongue C, Ward AC. Alternate TEL-JAK2 fusions associated with T cell acute lymphoblastic leukemia and atypical chronic myelogenous leukemia dissected in zebrafish. Haematologica. 2012;97(12): 1895-903.
35. Sabaawy HE, Azuma M, Embree LJ, Tsai HJ, Starost MF, Hickstein DD. TEL-AML1 transgenic zebrafish model of precursor B cell acute lymphoblastic leukemia. Proc Natl Acad Sci USA. 2006;103(41):15166-71.
36. Xiong JW, Yu Q, Zhang J, Mably JD. An acyltransferase controls the generation of hematopoietic and endothelial lineages in zebrafish. Circ Res. 2008;102(9):1057-64.
37. O'Sullivan LA, Noor SM, Trengove MC, Lewis RS, Liongue C, Sprigg NS, et al. Suppressor of cytokine signaling 1 regulates embryonic myelopoiesis independently of its effects on T cell development. J Immunol. 2011;186(8):4751-61.
38. Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method. Methods. 2001;25(4):402-8.
39. Jowett T. Double in situ hybridization techniques in zebrafish. Methods. 2001;23 (4):345-58.
40. Verduzco D, Amatruda JF. Analysis of cell proliferation, senescence and cell death in zebrafish embryos. Meth Cell Biol. 2011; 1011-19.
41. Montpetit A, Sinnett D. Comparative analysis of the ETV6 gene in vertegrate genomes from pufferfish to human. Oncogene. 2001;20(26):3437-42.
42. Liu F, Patient R. Genome-wide analysis of the zebrafish ETS family identifies three genes required for hemangioblast differentiation or angiogenesis. Circ Res. 2008; 103(10):1147-54.
43. Bertrand JY, Kim AD, Violette EP, Stachura DL, Cisson JL, Traver D. Definitive hematopoiesis initiates through a committed erythromyeloid progenitor in the zebrafish embryo. Development. 2007;134 (23):4147-56.
44. Gering M, Rodaway ARF, Gottens B, Patient R, Green AR. The SCL gene specifies haemangioblast development from early mesoderm. EMBO J. 1998;17(14):4029-45.
45. Liao EC, Paw BH, Oates AC, Pratt SJ, Postlethwait JH, Zon LI. SCL/Tal-1 transcription factor acts downstream of cloche to specify hematopoietic and vascular progenitors in zebrafish. Genes Dev. 1998;12(5): 621-6.
46. Lam EY, Hall CJ, Crosier PS, Crosier KE, Flores MV. Live imaging of Runx1 expression in the dorsal aorta tracks the emergence of blood progenitors from endothelial cells. Blood. 2010;116(6):909-14.
47. Paik EJ, Zon LI. Hematopoietic development in the zebrafish. Int J Dev Biol. 2010;54(6- 7):1127-37.
48. Quintana AM, Picchione F, Klein Geltink RI, Taylor MR, Grosveld GC. Zebrafish ETV7 regulates red blood cell development through the cholesterol synthesis pathway. Disease models & mechanisms. 2014;7 (2):265-70.
49. Takahashi W, Sasaki K, Kvomatsu N, Mitani K. TEL/ETV6 accelerates erythroid differentiation and inhibits megakaryocytic maturation in a human leukemia cell line UT- 7/GM. Cancer Sci. 2005;96(6):340-8.
50. Roukens MG, Alloul-Ramdhani M, Baan B, Kobayashi K, Peterson-Maduro J, van Dam H, et al. Control of endothelial sprouting by a Tel-CtBP complex. Nature Cell Biol. 2010;12(10):933-42.