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Volumn 37, Issue 3, 2015, Pages 253-262

TDP-43 modification in the hSOD1G93A amyotrophic lateral sclerosis mouse model

Author keywords

hSOD1G93A; Iron homeostasis; Motor neuron; TDP 43

Indexed keywords

TAR DNA BINDING PROTEIN; TRANSFERRIN; COPPER ZINC SUPEROXIDE DISMUTASE; DNA BINDING PROTEIN; HEME OXYGENASE 1; HMOX1 PROTEIN, MOUSE; IRON; MEMBRANE PROTEIN; SUPEROXIDE DISMUTASE; TDP-43 PROTEIN, MOUSE;

EID: 84920106094     PISSN: 01616412     EISSN: 17431328     Source Type: Journal    
DOI: 10.1179/1743132814Y.0000000443     Document Type: Article
Times cited : (12)

References (42)
  • 1
    • 84859621752 scopus 로고    scopus 로고
    • The complex molecular biology of amyotrophic lateral sclerosis (ALS)
    • Redler RL, Dokholyan NV. The complex molecular biology of amyotrophic lateral sclerosis (ALS). Prog Mol Biol Transl Sci. 2012;107:215–62.
    • (2012) Prog Mol Biol Transl Sci , vol.107 , pp. 215-262
    • Redler, R.L.1    Dokholyan, N.V.2
  • 2
    • 0028802665 scopus 로고
    • Amyotrophic lateral sclerosis
    • Eisen A. Amyotrophic lateral sclerosis. Intern Med. 1995;34:824–32.
    • (1995) Intern Med , vol.34 , pp. 824-832
    • Eisen, A.1
  • 3
    • 33847774429 scopus 로고    scopus 로고
    • Translational therapeutic strategies in amyotrophic lateral sclerosis
    • Ryu H, Ferrante RJ. Translational therapeutic strategies in amyotrophic lateral sclerosis. Mini Rev Med Chem. 2007;7:141–50.
    • (2007) Mini Rev Med Chem , vol.7 , pp. 141-150
    • Ryu, H.1    Ferrante, R.J.2
  • 4
    • 0027401203 scopus 로고
    • Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
    • Rosen DR, Siddique T, Patterson D, Figlewicz DA, Sapp P, Hentati A, et al.Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature. 1993;362:59–62.
    • (1993) Nature , vol.362 , pp. 59-62
    • Rosen, D.R.1    Siddique, T.2    Patterson, D.3    Figlewicz, D.A.4    Sapp, P.5    Hentati, A.6
  • 5
    • 0028284779 scopus 로고
    • Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation
    • Gurney ME, Pu H, Chiu AY, Dal Canto MC, Polchow CY, Alexander DD, et al. Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation. Science. 1994;264:1772–5.
    • (1994) Science , vol.264 , pp. 1772-1775
    • Gurney, M.E.1    Pu, H.2    Chiu, A.Y.3    Dal Canto, M.C.4    Polchow, C.Y.5    Alexander, D.D.6
  • 6
    • 84155171976 scopus 로고    scopus 로고
    • Understanding the role of TDP-43 and FUS/TLS in ALS and beyond
    • Da Cruz S, Cleveland DW. Understanding the role of TDP-43 and FUS/TLS in ALS and beyond. Curr Opin Neurobiol. 2011;21:904–19.
    • (2011) Curr Opin Neurobiol , vol.21 , pp. 904-919
    • Da Cruz, S.1    Cleveland, D.W.2
  • 8
    • 59249085091 scopus 로고    scopus 로고
    • Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathies
    • Neumann M, Kwong LK, Lee EB, Kremmer E, Flatley A, Xu Y, et al. Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathies. Acta Neuropathol. 2009;117:137–49.
    • (2009) Acta Neuropathol , vol.117 , pp. 137-149
    • Neumann, M.1    Kwong, L.K.2    Lee, E.B.3    Kremmer, E.4    Flatley, A.5    Xu, Y.6
  • 9
    • 33749632259 scopus 로고    scopus 로고
    • Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
    • Neumann M, Sampathu DM, Kwong LK, Truax AC, Micsenyi MC, Chou TT, et al. Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science. 2006;314:130–3.
    • (2006) Science , vol.314 , pp. 130-133
    • Neumann, M.1    Sampathu, D.M.2    Kwong, L.K.3    Truax, A.C.4    Micsenyi, M.C.5    Chou, T.T.6
  • 10
    • 78650680776 scopus 로고    scopus 로고
    • Regulation of TDP-43 aggregation by phosphorylation and p62/SQSTM1
    • Brady OA, Meng P, Zheng Y, Mao Y, Hu F. Regulation of TDP-43 aggregation by phosphorylation and p62/SQSTM1. J Neurochem. 2011;116:248–59.
    • (2011) J Neurochem , vol.116 , pp. 248-259
    • Brady, O.A.1    Meng, P.2    Zheng, Y.3    Mao, Y.4    Hu, F.5
  • 12
    • 46749138739 scopus 로고    scopus 로고
    • Enrichment of C-terminal fragments in TAR DNAbinding protein-43 cytoplasmic inclusions in brain but not in spinal cord of frontotemporal lobar degeneration and amyotrophic lateral sclerosis
    • Igaz LM, Kwong LK, Xu Y, Truax AC, Uryu K, Neumann M, et al. Enrichment of C-terminal fragments in TAR DNAbinding protein-43 cytoplasmic inclusions in brain but not in spinal cord of frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Am J Pathol. 2008;173:182–94.
    • (2008) Am J Pathol , vol.173 , pp. 182-194
    • Igaz, L.M.1    Kwong, L.K.2    Xu, Y.3    Truax, A.C.4    Uryu, K.5    Neumann, M.6
  • 13
    • 80051660738 scopus 로고    scopus 로고
    • Iron chelation and neuroprotection in neurodegenerative diseases
    • Li X, Jankovic J, Le W. Iron chelation and neuroprotection in neurodegenerative diseases. J Neural Transm. 2011;118:473–7.
    • (2011) J Neural Transm , vol.118 , pp. 473-477
    • Li, X.1    Jankovic, J.2    Le, W.3
  • 14
    • 84555179169 scopus 로고    scopus 로고
    • Dysregulation of iron metabolism in Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis
    • Oshiro S, Morioka MS, Kikuchi M. Dysregulation of iron metabolism in Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis. Adv Pharmacol Sci. 2011;2011:378278.
    • (2011) Adv Pharmacol Sci , vol.2011 , pp. 378278
    • Oshiro, S.1    Morioka, M.S.2    Kikuchi, M.3
  • 16
    • 77957904877 scopus 로고    scopus 로고
    • Bee venom attenuates neuroinflammatory events and extends survival in amyotrophic lateral sclerosis models
    • Yang EJ, Jiang JH, Lee SM, Yang SC, Hwang HS, Lee MS, et al. Bee venom attenuates neuroinflammatory events and extends survival in amyotrophic lateral sclerosis models. J Neuroinflammation. 2010;7:69.
    • (2010) J Neuroinflammation , vol.7 , pp. 69
    • Yang, E.J.1    Jiang, J.H.2    Lee, S.M.3    Yang, S.C.4    Hwang, H.S.5    Lee, M.S.6
  • 17
    • 0030901162 scopus 로고    scopus 로고
    • Fluoro-Jade: A novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration
    • Schmued LC, Albertson C, Slikker W Jr. Fluoro-Jade: a novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration. Brain Res. 1997;751:37–46.
    • (1997) Brain Res , vol.751 , pp. 37-46
    • Schmued, L.C.1    Albertson, C.2    Slikker, W.3
  • 18
    • 0034607595 scopus 로고    scopus 로고
    • Temporal progression of kainic acid induced neuronal and myelin degeneration in the rat forebrain
    • Hopkins KJ, Wang G, Schmued LC. Temporal progression of kainic acid induced neuronal and myelin degeneration in the rat forebrain. Brain Res. 2000;864:69–80.
    • (2000) Brain Res , vol.864 , pp. 69-80
    • Hopkins, K.J.1    Wang, G.2    Schmued, L.C.3
  • 20
    • 77952105020 scopus 로고    scopus 로고
    • Decreased level of 5- methyltetrahydrofolate: A potential biomarker for pre-symptomatic amyotrophic lateral sclerosis
    • Zhang X, Chen S, Li L, Wang Q, Le W. Decreased level of 5- methyltetrahydrofolate: a potential biomarker for pre-symptomatic amyotrophic lateral sclerosis. J Neurol Sci. 2010;293:102–5.
    • (2010) J Neurol Sci , vol.293 , pp. 102-105
    • Zhang, X.1    Chen, S.2    Li, L.3    Wang, Q.4    Le, W.5
  • 21
    • 84866667912 scopus 로고    scopus 로고
    • Therapeutic effects of DL-3-N-butylphthalide in a transgenic mouse model of amyotrophic lateral sclerosis
    • Feng XH, Yuan W, Peng Y, Liu MS, Cui LY. Therapeutic effects of DL-3-N-butylphthalide in a transgenic mouse model of amyotrophic lateral sclerosis. Chin Med J. 2012;125:1760–6.
    • (2012) Chin Med J , vol.125 , pp. 1760-1766
    • Feng, X.H.1    Yuan, W.2    Peng, Y.3    Liu, M.S.4    Cui, L.Y.5
  • 22
    • 0029017315 scopus 로고
    • Aluminum, calcium, and iron in the spinal cord of patients with sporadic amyotrophic lateral sclerosis using laser microprobe mass spectroscopy: A preliminary study
    • Kasarskis EJ, Tandon L, Lovell MA, Ehmann WD. Aluminum, calcium, and iron in the spinal cord of patients with sporadic amyotrophic lateral sclerosis using laser microprobe mass spectroscopy: a preliminary study. J Neurol Sci. 1995;130:203–8.
    • (1995) J Neurol Sci , vol.130 , pp. 203-208
    • Kasarskis, E.J.1    Tandon, L.2    Lovell, M.A.3    Ehmann, W.D.4
  • 23
    • 0035240305 scopus 로고    scopus 로고
    • Progress in the pathogenesis of amyotrophic lateral sclerosis
    • Shaw CE, al-Chalabi A, Leigh N. Progress in the pathogenesis of amyotrophic lateral sclerosis. Curr Neurol Neurosci Rep. 2001;1:69–76.
    • (2001) Curr Neurol Neurosci Rep , vol.1 , pp. 69-76
    • Shaw, C.E.1    Al-Chalabi, A.2    Leigh, N.3
  • 24
    • 33750716074 scopus 로고    scopus 로고
    • TDP-43 is a component of ubiquitin-positive taunegative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
    • Arai T, Hasegawa M, Akiyama H, Ikeda K, Nonaka T, Mori H, et al. TDP-43 is a component of ubiquitin-positive taunegative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Biochem Biophys Res Commun. 2006;351:602–11.
    • (2006) Biochem Biophys Res Commun , vol.351 , pp. 602-611
    • Arai, T.1    Hasegawa, M.2    Akiyama, H.3    Ikeda, K.4    Nonaka, T.5    Mori, H.6
  • 28
    • 34247475338 scopus 로고    scopus 로고
    • Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons
    • Nagai M, Re DB, Nagata T, Chalazonitis A, Jessell TM, Wichterle H, et al. Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons. Nat Neurosci. 2007;10:615–22.
    • (2007) Nat Neurosci , vol.10 , pp. 615-622
    • Nagai, M.1    Re, D.B.2    Nagata, T.3    Chalazonitis, A.4    Jessell, T.M.5    Wichterle, H.6
  • 29
    • 34247473080 scopus 로고    scopus 로고
    • Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model
    • Di Giorgio FP, Carrasco MA, Siao MC, Maniatis T, Eggan K. Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model. Nat Neurosci. 2007;10:608–14.
    • (2007) Nat Neurosci , vol.10 , pp. 608-614
    • Di Giorgio, F.P.1    Carrasco, M.A.2    Siao, M.C.3    Maniatis, T.4    Eggan, K.5
  • 31
    • 0029030610 scopus 로고
    • Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis
    • Rothstein JD, Van Kammen M, Levey AI, Martin LJ, Kuncl RW. Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis. Ann Neurol. 1995;38:73–84.
    • (1995) Ann Neurol , vol.38 , pp. 73-84
    • Rothstein, J.D.1    Van Kammen, M.2    Levey, A.I.3    Martin, L.J.4    Kuncl, R.W.5
  • 32
    • 80052936462 scopus 로고    scopus 로고
    • Pathological hallmarks of amyotrophic lateral sclerosis/ frontotemporal lobar degeneration in transgenic mice produced with TDP-43 genomic fragments
    • Swarup V, Phaneuf D, Bareil C, Robertson J, Rouleau GA, Kriz J, et al. Pathological hallmarks of amyotrophic lateral sclerosis/ frontotemporal lobar degeneration in transgenic mice produced with TDP-43 genomic fragments. Brain. 2011;134:2610–26.
    • (2011) Brain , vol.134 , pp. 2610-2626
    • Swarup, V.1    Phaneuf, D.2    Bareil, C.3    Robertson, J.4    Rouleau, G.A.5    Kriz, J.6
  • 33
    • 84872465426 scopus 로고    scopus 로고
    • Premature death of TDP-43 (A315T) transgenic mice due to gastrointestinal complications prior to development of full neurological symptoms of amyotrophic lateral sclerosis
    • Esmaeili MA, Panahi M, Yadav S, Hennings L, Kiaei M. Premature death of TDP-43 (A315T) transgenic mice due to gastrointestinal complications prior to development of full neurological symptoms of amyotrophic lateral sclerosis. Int J Exp Pathol. 2013;94:56–64.
    • (2013) Int J Exp Pathol , vol.94 , pp. 56-64
    • Esmaeili, M.A.1    Panahi, M.2    Yadav, S.3    Hennings, L.4    Kiaei, M.5
  • 35
    • 84880217322 scopus 로고    scopus 로고
    • Expression of ALS-linked TDP-43 mutant in astrocytes causes non-cell-autonomous motor neuron death in rats
    • Tong J, Huang C, Bi F, Wu Q, Huang B, Liu X, et al. Expression of ALS-linked TDP-43 mutant in astrocytes causes non-cell-autonomous motor neuron death in rats. EMBO J. 2013;32:1917–26.
    • (2013) EMBO J , vol.32 , pp. 1917-1926
    • Tong, J.1    Huang, C.2    Bi, F.3    Wu, Q.4    Huang, B.5    Liu, X.6
  • 36
    • 84871734357 scopus 로고    scopus 로고
    • A role for calpain-dependent cleavage of TDP- 43 in amyotrophic lateral sclerosis pathology
    • Yamashita T, Hideyama T, Hachiga K, Teramoto S, Takano J, Iwata N, et al. A role for calpain-dependent cleavage of TDP- 43 in amyotrophic lateral sclerosis pathology. Nat Commun. 2012;3:1307.
    • (2012) Nat Commun , vol.3 , pp. 1307
    • Yamashita, T.1    Hideyama, T.2    Hachiga, K.3    Teramoto, S.4    Takano, J.5    Iwata, N.6
  • 37
    • 77957558614 scopus 로고    scopus 로고
    • Calpastatin reduces toxicity of SOD1G93A in a culture model of amyotrophic lateral sclerosis
    • Tradewell ML, Durham HD. Calpastatin reduces toxicity of SOD1G93A in a culture model of amyotrophic lateral sclerosis. Neuroreport. 2010;21:976–9.
    • (2010) Neuroreport , vol.21 , pp. 976-979
    • Tradewell, M.L.1    Durham, H.D.2
  • 38
    • 84860218803 scopus 로고    scopus 로고
    • Novel therapeutic approach for neurodegenerative pathologies: Multitarget ironchelating drugs regulating hypoxia-inducible factor 1 signal transduction pathway
    • Weinreb O, Amit T, Mandel S, Youdim MB. Novel therapeutic approach for neurodegenerative pathologies: multitarget ironchelating drugs regulating hypoxia-inducible factor 1 signal transduction pathway. Neurodegener Dis. 2012;10:112–5.
    • (2012) Neurodegener Dis , vol.10 , pp. 112-115
    • Weinreb, O.1    Amit, T.2    Mandel, S.3    Youdim, M.B.4
  • 40
    • 79958787596 scopus 로고    scopus 로고
    • Prevention of motor neuron degeneration by novel iron chelators in SOD1(G93A) transgenic mice of amyotrophic lateral sclerosis
    • Wang Q, Zhang X, Chen S, Zhang X, Zhang S, Youdium M, et al. Prevention of motor neuron degeneration by novel iron chelators in SOD1(G93A) transgenic mice of amyotrophic lateral sclerosis. Neurodegener Dis. 2011;8:310–21.
    • (2011) Neurodegener Dis , vol.8 , pp. 310-321
    • Wang, Q.1    Zhang, X.2    Chen, S.3    Zhang, X.4    Zhang, S.5    Youdium, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.