Mechanism of p-Hydroxybenzoate ester-induced mitochondrial dysfunction and cytotoxicity in isolated rat hepatocytes

Biochemical Pharmacology

Volumn 55, Issue 11, 1998, Pages 1907-1914

  Nakagawa, Yoshio ^a   Moldéus, Peter ^b  

^a TOKYO METROPOLITAN INSTITUTE OF PUBLIC HEALTH   (Japan)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Cytotoxicity; Mitochondrial dysfunction; p Hydroxybenzoate esters; Parabens; Rat hepatocytes antimicrobial preservative

Indexed keywords

4 HYDROXYBENZOIC ACID; 4 HYDROXYBENZOIC ACID ESTER; ADENINE NUCLEOTIDE; ADENOSINE TRIPHOSPHATE; DIMPYLATE; GLUTATHIONE;

ANIMAL CELL; ARTICLE; CELL DEATH; CELL VIABILITY; CYTOTOXICITY; DOSE TIME EFFECT RELATION; DRUG MECHANISM; DRUG METABOLISM; HYDROLYSIS; LIPID PEROXIDATION; LIVER MITOCHONDRION; MALE; MITOCHONDRIAL RESPIRATION; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; RAT;

ADENINE NUCLEOTIDES; ANIMALS; CELL DEATH; CELL RESPIRATION; FOOD PRESERVATIVES; LIVER; MALE; MEMBRANE POTENTIALS; MITOCHONDRIA, LIVER; PARABENS; PRESERVATIVES, PHARMACEUTICAL; RATS; RATS, INBRED F344;

EID: 0345368076     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(98)00097-5     Document Type: Article

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