Role of mitochondrial dysfunction in cardiac glycoside toxicity

Journal of Molecular and Cellular Cardiology

Volumn 49, Issue 5, 2010, Pages 728-736

  Liu, Ting ^a   Brown, David A ^b   O'Rourke, Brian ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EAST CAROLINA UNIVERSITY   (United States)

Author keywords

Arrhythmias; Cardiac glycosides; Energy metabolism; Heart failure; Ion transport; Na+ Ca2+ exchanger

Indexed keywords

7 CHLORO 5 (2 CHLOROPHENYL) 1,5 DIHYDRO 4,1 BENZOTHIAZEPIN 2(3H) ONE; CALCIUM ION; CARDIAC GLYCOSIDE; ISOPRENALINE; NICOTINAMIDE ADENINE DINUCLEOTIDE; OUABAIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; SODIUM CALCIUM EXCHANGE PROTEIN; SODIUM ION;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARRHYTHMOGENESIS; ARTICLE; BETA ADRENERGIC STIMULATION; CALCIUM TRANSPORT; CELL ISOLATION; CONTROLLED STUDY; CYTOTOXICITY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DOSE RESPONSE; DRUG POTENTIATION; ENERGY METABOLISM; GUINEA PIG; HEART ARRHYTHMIA; HEART DEPOLARIZATION; HEART FAILURE; HEART FUNCTION; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HEART VENTRICLE OVERLOAD; IN VIVO STUDY; INOTROPISM; ION TRANSPORT; ISOLATED HEART; MITOCHONDRIAL RESPIRATION; NONHUMAN; OSCILLATION; OXIDATION; OXIDATION REDUCTION POTENTIAL; OXIDATION REDUCTION REACTION; OXYGEN CONSUMPTION; PRIORITY JOURNAL; SODIUM CALCIUM EXCHANGE;

ACTION POTENTIALS; ANIMALS; ARRHYTHMIAS, CARDIAC; CALCIUM; CARDIAC GLYCOSIDES; CLONAZEPAM; GUINEA PIGS; HEART; ISOPROTERENOL; MITOCHONDRIA; NAD; OUABAIN; OXYGEN CONSUMPTION; PERFUSION; SODIUM; SODIUM-CALCIUM EXCHANGER; THIAZEPINES;

STROPHANTHUS GRATUS;

EID: 77957242874     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2010.06.012     Document Type: Article

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