Mitochondrial protein sorting as a therapeutic target for ATP synthase disorders

Nature Communications

Volumn 5, Issue , 2014, Pages

  Aiyar, Raeka S ^a   Bohnert, Maria ^b   Duvezin Caubet, Stéphane ^c,d   Voisset, Cécile ^e   Gagneur, Julien ^a,h   Fritsch, Emilie S ^a   Couplan, Elodie ^e   Von Der Malsburg, Karina ^b,i   Funaya, Charlotta ^a   Soubigou, Flavie ^e   Courtin, Florence ^c,d   Suresh, Sundari ^f   Kucharczyk, Roza ^g   Evrard, Justine ^e   Antony, Claude ^a   St onge, Robert P ^f   Blondel, Marc ^e   Di Rago, Jean Paul ^c,d   Van Der Laan, Martin ^b   Steinmetz, Lars M ^a,f  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

^c UNIVERSITÉ DE BORDEAUX   (France)

^d Institut de Biochimie et Genetique Cellulaires   (France)

^e UNIVERSITÉ DE BRETAGNE OCCIDENTALE   (France)

^f STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g INSTITUTE OF BIOCHEMISTRY AND BIOPHYSICS   (Poland)

^h UNIVERSITY OF MUNICH   (Germany)

ⁱ MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME C OXIDASE; MEMBRANE PROTEIN; MITOCHONDRIAL PROTEIN; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; PYRITHIONE SODIUM; TRANSLOCASE OF INNER MITOCHONDRIAL MEMBRANE 21; TRANSLOCASE OF INNER MITOCHONDRIAL MEMBRANE 23; UNCLASSIFIED DRUG; ANTIFUNGAL AGENT; CARRIER PROTEIN; NUCLEAR PROTEIN; PYRIDINE DERIVATIVE; PYRITHIONE; SACCHAROMYCES CEREVISIAE PROTEIN; THIOKETONE; TIM23 PROTEIN, S CEREVISIAE; TIMM23 PROTEIN, HUMAN;

BIOCHEMICAL COMPOSITION; CYTOLOGY; ENZYME ACTIVITY; GENOMICS; MITOCHONDRIAL DNA; PROTEIN; YEAST;

ARTICLE; BIOGENESIS; CELL FUNCTION; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYBRID; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA MODIFICATION; DRUG REPOSITIONING; ENZYME SYNTHESIS; GENE DELETION; GENE INTERACTION; GENE OVEREXPRESSION; GENETIC PROCEDURES; HUMAN; HUMAN CELL; IN VITRO STUDY; LEIGH DISEASE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; MOUSE; NARP SYNDROME; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PHENOTYPE; PROTEIN TARGETING; SACCHAROMYCES CEREVISIAE; STEADY STATE; THERAPY EFFECT; TREATMENT RESPONSE; CELL NUCLEUS; DEFICIENCY; DRUG DATABASE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MITOCHONDRIAL DISEASES; MOLECULARLY TARGETED THERAPY; MUTATION; PATHOLOGY; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

ANTIFUNGAL AGENTS; CELL NUCLEUS; DATABASES, PHARMACEUTICAL; DRUG REPOSITIONING; GENE EXPRESSION REGULATION; HUMANS; MEMBRANE TRANSPORT PROTEINS; MITOCHONDRIA; MITOCHONDRIAL DISEASES; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MITOCHONDRIAL PROTON-TRANSLOCATING ATPASES; MOLECULAR TARGETED THERAPY; MUTATION; NUCLEAR PROTEINS; OXIDATIVE PHOSPHORYLATION; PROTEIN TRANSPORT; PYRIDINES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SIGNAL TRANSDUCTION; THIONES;

EID: 84920001091     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms6585     Document Type: Article

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