-
1
-
-
37849048003
-
Discovery of genes activated by the mitochondrial unfolded protein response (mtUPR) and cognate promoter elements
-
J.E. Aldridge, T. Horibe, and N.J. Hoogenraad Discovery of genes activated by the mitochondrial unfolded protein response (mtUPR) and cognate promoter elements PLoS ONE 2 2007 e874
-
(2007)
PLoS ONE
, vol.2
, pp. 874
-
-
Aldridge, J.E.1
Horibe, T.2
Hoogenraad, N.J.3
-
2
-
-
67649450485
-
Translation attenuation through eIF2alpha phosphorylation prevents oxidative stress and maintains the differentiated state in beta cells
-
S.H. Back, D. Scheuner, J. Han, B. Song, M. Ribick, J. Wang, R.D. Gildersleeve, S. Pennathur, and R.J. Kaufman Translation attenuation through eIF2alpha phosphorylation prevents oxidative stress and maintains the differentiated state in beta cells Cell Metab. 10 2009 13 26
-
(2009)
Cell Metab.
, vol.10
, pp. 13-26
-
-
Back, S.H.1
Scheuner, D.2
Han, J.3
Song, B.4
Ribick, M.5
Wang, J.6
Gildersleeve, R.D.7
Pennathur, S.8
Kaufman, R.J.9
-
4
-
-
84864065342
-
Protective coupling of mitochondrial function and protein synthesis via the eIF2α kinase GCN-2
-
B.M. Baker, A.M. Nargund, T. Sun, and C.M. Haynes Protective coupling of mitochondrial function and protein synthesis via the eIF2α kinase GCN-2 PLoS Genet. 8 2012 e1002760
-
(2012)
PLoS Genet.
, vol.8
, pp. 1002760
-
-
Baker, B.M.1
Nargund, A.M.2
Sun, T.3
Haynes, C.M.4
-
5
-
-
0033612325
-
Genetic and structural characterization of the human mitochondrial inner membrane translocase
-
M.F. Bauer, K. Gempel, A.S. Reichert, G.A. Rappold, P. Lichtner, K.D. Gerbitz, W. Neupert, M. Brunner, and S. Hofmann Genetic and structural characterization of the human mitochondrial inner membrane translocase J. Mol. Biol. 289 1999 69 82
-
(1999)
J. Mol. Biol.
, vol.289
, pp. 69-82
-
-
Bauer, M.F.1
Gempel, K.2
Reichert, A.S.3
Rappold, G.A.4
Lichtner, P.5
Gerbitz, K.D.6
Neupert, W.7
Brunner, M.8
Hofmann, S.9
-
6
-
-
68749112707
-
Importing mitochondrial proteins: Machineries and mechanisms
-
A. Chacinska, C.M. Koehler, D. Milenkovic, T. Lithgow, and N. Pfanner Importing mitochondrial proteins: machineries and mechanisms Cell 138 2009 628 644
-
(2009)
Cell
, vol.138
, pp. 628-644
-
-
Chacinska, A.1
Koehler, C.M.2
Milenkovic, D.3
Lithgow, T.4
Pfanner, N.5
-
7
-
-
30044444717
-
A genomewide screen for petite-negative yeast strains yields a new subunit of the i-AAA protease complex
-
C.D. Dunn, M.S. Lee, F.A. Spencer, and R.E. Jensen A genomewide screen for petite-negative yeast strains yields a new subunit of the i-AAA protease complex Mol. Biol. Cell 17 2006 213 226
-
(2006)
Mol. Biol. Cell
, vol.17
, pp. 213-226
-
-
Dunn, C.D.1
Lee, M.S.2
Spencer, F.A.3
Jensen, R.E.4
-
8
-
-
59449100177
-
Mgr3p and Mgr1p are adaptors for the mitochondrial i-AAA protease complex
-
C.D. Dunn, Y. Tamura, H. Sesaki, and R.E. Jensen Mgr3p and Mgr1p are adaptors for the mitochondrial i-AAA protease complex Mol. Biol. Cell 19 2008 5387 5397
-
(2008)
Mol. Biol. Cell
, vol.19
, pp. 5387-5397
-
-
Dunn, C.D.1
Tamura, Y.2
Sesaki, H.3
Jensen, R.E.4
-
9
-
-
78650944949
-
The cell-non-autonomous nature of electron transport chain-mediated longevity
-
J. Durieux, S. Wolff, and A. Dillin The cell-non-autonomous nature of electron transport chain-mediated longevity Cell 144 2011 79 91
-
(2011)
Cell
, vol.144
, pp. 79-91
-
-
Durieux, J.1
Wolff, S.2
Dillin, A.3
-
11
-
-
18744413882
-
The mitochondrial presequence translocase: An essential role of Tim50 in directing preproteins to the import channel
-
A. Geissler, A. Chacinska, K.N. Truscott, N. Wiedemann, K. Brandner, A. Sickmann, H.E. Meyer, C. Meisinger, N. Pfanner, and P. Rehling The mitochondrial presequence translocase: an essential role of Tim50 in directing preproteins to the import channel Cell 111 2002 507 518
-
(2002)
Cell
, vol.111
, pp. 507-518
-
-
Geissler, A.1
Chacinska, A.2
Truscott, K.N.3
Wiedemann, N.4
Brandner, K.5
Sickmann, A.6
Meyer, H.E.7
Meisinger, C.8
Pfanner, N.9
Rehling, P.10
-
12
-
-
39449100859
-
Intra-mitochondrial degradation of Tim23 curtails the survival of cells rescued from apoptosis by caspase inhibitors
-
C.G. Goemans, P. Boya, C.J. Skirrow, and A.M. Tolkovsky Intra-mitochondrial degradation of Tim23 curtails the survival of cells rescued from apoptosis by caspase inhibitors Cell Death Differ. 15 2008 545 554
-
(2008)
Cell Death Differ.
, vol.15
, pp. 545-554
-
-
Goemans, C.G.1
Boya, P.2
Skirrow, C.J.3
Tolkovsky, A.M.4
-
13
-
-
0033634654
-
Regulated translation initiation controls stress-induced gene expression in mammalian cells
-
H.P. Harding, I. Novoa, Y. Zhang, H. Zeng, R. Wek, M. Schapira, and D. Ron Regulated translation initiation controls stress-induced gene expression in mammalian cells Mol. Cell 6 2000 1099 1108
-
(2000)
Mol. Cell
, vol.6
, pp. 1099-1108
-
-
Harding, H.P.1
Novoa, I.2
Zhang, Y.3
Zeng, H.4
Wek, R.5
Schapira, M.6
Ron, D.7
-
14
-
-
0036437307
-
Transcriptional and translational control in the Mammalian unfolded protein response
-
H.P. Harding, M. Calfon, F. Urano, I. Novoa, and D. Ron Transcriptional and translational control in the Mammalian unfolded protein response Annu. Rev. Cell Dev. Biol. 18 2002 575 599
-
(2002)
Annu. Rev. Cell Dev. Biol.
, vol.18
, pp. 575-599
-
-
Harding, H.P.1
Calfon, M.2
Urano, F.3
Novoa, I.4
Ron, D.5
-
15
-
-
0037353039
-
An integrated stress response regulates amino acid metabolism and resistance to oxidative stress
-
H.P. Harding, Y. Zhang, H. Zeng, I. Novoa, P.D. Lu, M. Calfon, N. Sadri, C. Yun, B. Popko, and R. Paules An integrated stress response regulates amino acid metabolism and resistance to oxidative stress Mol. Cell 11 2003 619 633
-
(2003)
Mol. Cell
, vol.11
, pp. 619-633
-
-
Harding, H.P.1
Zhang, Y.2
Zeng, H.3
Novoa, I.4
Lu, P.D.5
Calfon, M.6
Sadri, N.7
Yun, C.8
Popko, B.9
Paules, R.10
-
16
-
-
78649728763
-
The mitochondrial UPR - Protecting organelle protein homeostasis
-
C.M. Haynes, and D. Ron The mitochondrial UPR - protecting organelle protein homeostasis J. Cell Sci. 123 2010 3849 3855
-
(2010)
J. Cell Sci.
, vol.123
, pp. 3849-3855
-
-
Haynes, C.M.1
Ron, D.2
-
17
-
-
34848861368
-
ClpP mediates activation of a mitochondrial unfolded protein response in C. Elegans
-
C.M. Haynes, K. Petrova, C. Benedetti, Y. Yang, and D. Ron ClpP mediates activation of a mitochondrial unfolded protein response in C. elegans Dev. Cell 13 2007 467 480
-
(2007)
Dev. Cell
, vol.13
, pp. 467-480
-
-
Haynes, C.M.1
Petrova, K.2
Benedetti, C.3
Yang, Y.4
Ron, D.5
-
18
-
-
76849100919
-
The matrix peptide exporter HAF-1 signals a mitochondrial UPR by activating the transcription factor ZC376.7 in C. Elegans
-
C.M. Haynes, Y. Yang, S.P. Blais, T.A. Neubert, and D. Ron The matrix peptide exporter HAF-1 signals a mitochondrial UPR by activating the transcription factor ZC376.7 in C. elegans Mol. Cell 37 2010 529 540
-
(2010)
Mol. Cell
, vol.37
, pp. 529-540
-
-
Haynes, C.M.1
Yang, Y.2
Blais, S.P.3
Neubert, T.A.4
Ron, D.5
-
19
-
-
12844259491
-
GCN2 phosphorylation of eIF2alpha activates NF-kappaB in response to UV irradiation
-
H.Y. Jiang, and R.C. Wek GCN2 phosphorylation of eIF2alpha activates NF-kappaB in response to UV irradiation Biochem. J. 385 2005 371 380
-
(2005)
Biochem. J.
, vol.385
, pp. 371-380
-
-
Jiang, H.Y.1
Wek, R.C.2
-
20
-
-
0035949432
-
An engineered transthyretin monomer that is nonamyloidogenic, unless it is partially denatured
-
X. Jiang, C.S. Smith, H.M. Petrassi, P. Hammarström, J.T. White, J.C. Sacchettini, and J.W. Kelly An engineered transthyretin monomer that is nonamyloidogenic, unless it is partially denatured Biochemistry 40 2001 11442 11452
-
(2001)
Biochemistry
, vol.40
, pp. 11442-11452
-
-
Jiang, X.1
Smith, C.S.2
Petrassi, H.M.3
Hammarström, P.4
White, J.T.5
Sacchettini, J.C.6
Kelly, J.W.7
-
21
-
-
0043133837
-
Phosphorylation of the alpha subunit of eukaryotic initiation factor 2 is required for activation of NF-kappaB in response to diverse cellular stresses
-
H.Y. Jiang, S.A. Wek, B.C. McGrath, D. Scheuner, R.J. Kaufman, D.R. Cavener, and R.C. Wek Phosphorylation of the alpha subunit of eukaryotic initiation factor 2 is required for activation of NF-kappaB in response to diverse cellular stresses Mol. Cell. Biol. 23 2003 5651 5663
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 5651-5663
-
-
Jiang, H.Y.1
Wek, S.A.2
McGrath, B.C.3
Scheuner, D.4
Kaufman, R.J.5
Cavener, D.R.6
Wek, R.C.7
-
22
-
-
0040034984
-
Biogenesis of Tim23 and Tim17, integral components of the TIM machinery for matrix-targeted preproteins
-
K. Káldi, M.F. Bauer, C. Sirrenberg, W. Neupert, and M. Brunner Biogenesis of Tim23 and Tim17, integral components of the TIM machinery for matrix-targeted preproteins EMBO J. 17 1998 1569 1576
-
(1998)
EMBO J.
, vol.17
, pp. 1569-1576
-
-
Káldi, K.1
Bauer, M.F.2
Sirrenberg, C.3
Neupert, W.4
Brunner, M.5
-
23
-
-
34250369119
-
Protein degradation within mitochondria: Versatile activities of AAA proteases and other peptidases
-
M. Koppen, and T. Langer Protein degradation within mitochondria: versatile activities of AAA proteases and other peptidases Crit. Rev. Biochem. Mol. Biol. 42 2007 221 242
-
(2007)
Crit. Rev. Biochem. Mol. Biol.
, vol.42
, pp. 221-242
-
-
Koppen, M.1
Langer, T.2
-
24
-
-
58449084895
-
Divergent effects of PERK and IRE1 signaling on cell viability
-
J.H. Lin, H. Li, Y. Zhang, D. Ron, and P. Walter Divergent effects of PERK and IRE1 signaling on cell viability PLoS ONE 4 2009 e4170
-
(2009)
PLoS ONE
, vol.4
, pp. 4170
-
-
Lin, J.H.1
Li, H.2
Zhang, Y.3
Ron, D.4
Walter, P.5
-
25
-
-
0842285401
-
Cytoprotection by pre-emptive conditional phosphorylation of translation initiation factor 2
-
P.D. Lu, C. Jousse, S.J. Marciniak, Y. Zhang, I. Novoa, D. Scheuner, R.J. Kaufman, D. Ron, and H.P. Harding Cytoprotection by pre-emptive conditional phosphorylation of translation initiation factor 2 EMBO J. 23 2004 169 179
-
(2004)
EMBO J.
, vol.23
, pp. 169-179
-
-
Lu, P.D.1
Jousse, C.2
Marciniak, S.J.3
Zhang, Y.4
Novoa, I.5
Scheuner, D.6
Kaufman, R.J.7
Ron, D.8
Harding, H.P.9
-
26
-
-
20144378698
-
Heme-regulated inhibitor kinase-mediated phosphorylation of eukaryotic translation initiation factor 2 inhibits translation, induces stress granule formation, and mediates survival upon arsenite exposure
-
E. McEwen, N. Kedersha, B. Song, D. Scheuner, N. Gilks, A. Han, J.J. Chen, P. Anderson, and R.J. Kaufman Heme-regulated inhibitor kinase-mediated phosphorylation of eukaryotic translation initiation factor 2 inhibits translation, induces stress granule formation, and mediates survival upon arsenite exposure J. Biol. Chem. 280 2005 16925 16933
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 16925-16933
-
-
McEwen, E.1
Kedersha, N.2
Song, B.3
Scheuner, D.4
Gilks, N.5
Han, A.6
Chen, J.J.7
Anderson, P.8
Kaufman, R.J.9
-
27
-
-
84864744900
-
Mitochondrial import efficiency of ATFS-1 regulates mitochondrial UPR activation
-
A.M. Nargund, M.W. Pellegrino, C.J. Fiorese, B.M. Baker, and C.M. Haynes Mitochondrial import efficiency of ATFS-1 regulates mitochondrial UPR activation Science 337 2012 587 590
-
(2012)
Science
, vol.337
, pp. 587-590
-
-
Nargund, A.M.1
Pellegrino, M.W.2
Fiorese, C.J.3
Baker, B.M.4
Haynes, C.M.5
-
28
-
-
0035947778
-
Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha
-
I. Novoa, H. Zeng, H.P. Harding, and D. Ron Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha J. Cell Biol. 153 2001 1011 1022
-
(2001)
J. Cell Biol.
, vol.153
, pp. 1011-1022
-
-
Novoa, I.1
Zeng, H.2
Harding, H.P.3
Ron, D.4
-
29
-
-
84858376953
-
Mitochondria: In sickness and in health
-
J. Nunnari, and A. Suomalainen Mitochondria: in sickness and in health Cell 148 2012 1145 1159
-
(2012)
Cell
, vol.148
, pp. 1145-1159
-
-
Nunnari, J.1
Suomalainen, A.2
-
30
-
-
33750986200
-
A new function in translocation for the mitochondrial i-AAA protease Yme1: Import of polynucleotide phosphorylase into the intermembrane space
-
R.N. Rainey, J.D. Glavin, H.W. Chen, S.W. French, M.A. Teitell, and C.M. Koehler A new function in translocation for the mitochondrial i-AAA protease Yme1: import of polynucleotide phosphorylase into the intermembrane space Mol. Cell. Biol. 26 2006 8488 8497
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 8488-8497
-
-
Rainey, R.N.1
Glavin, J.D.2
Chen, H.W.3
French, S.W.4
Teitell, M.A.5
Koehler, C.M.6
-
31
-
-
84858791998
-
Mitochondrial quality control: A matter of life and death for neurons
-
E.I. Rugarli, and T. Langer Mitochondrial quality control: a matter of life and death for neurons EMBO J. 31 2012 1336 1349
-
(2012)
EMBO J.
, vol.31
, pp. 1336-1349
-
-
Rugarli, E.I.1
Langer, T.2
-
32
-
-
84875968253
-
Surveillance-activated defenses block the ROS-induced mitochondrial unfolded protein response
-
E.D. Runkel, S. Liu, R. Baumeister, and E. Schulze Surveillance-activated defenses block the ROS-induced mitochondrial unfolded protein response PLoS Genet. 9 2013 e1003346
-
(2013)
PLoS Genet.
, vol.9
, pp. 1003346
-
-
Runkel, E.D.1
Liu, S.2
Baumeister, R.3
Schulze, E.4
-
34
-
-
0034973982
-
Translational control is required for the unfolded protein response and in vivo glucose homeostasis
-
D. Scheuner, B. Song, E. McEwen, C. Liu, R. Laybutt, P. Gillespie, T. Saunders, S. Bonner-Weir, and R.J. Kaufman Translational control is required for the unfolded protein response and in vivo glucose homeostasis Mol. Cell 7 2001 1165 1176
-
(2001)
Mol. Cell
, vol.7
, pp. 1165-1176
-
-
Scheuner, D.1
Song, B.2
McEwen, E.3
Liu, C.4
Laybutt, R.5
Gillespie, P.6
Saunders, T.7
Bonner-Weir, S.8
Kaufman, R.J.9
-
35
-
-
77956090193
-
Mitochondrial protein import: From proteomics to functional mechanisms
-
O. Schmidt, N. Pfanner, and C. Meisinger Mitochondrial protein import: from proteomics to functional mechanisms Nat. Rev. Mol. Cell Biol. 11 2010 655 667
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 655-667
-
-
Schmidt, O.1
Pfanner, N.2
Meisinger, C.3
-
36
-
-
78651487830
-
Regulation of mitochondrial protein import by cytosolic kinases
-
O. Schmidt, A.B. Harbauer, S. Rao, B. Eyrich, R.P. Zahedi, D. Stojanovski, B. Schönfisch, B. Guiard, A. Sickmann, N. Pfanner, and C. Meisinger Regulation of mitochondrial protein import by cytosolic kinases Cell 144 2011 227 239
-
(2011)
Cell
, vol.144
, pp. 227-239
-
-
Schmidt, O.1
Harbauer, A.B.2
Rao, S.3
Eyrich, B.4
Zahedi, R.P.5
Stojanovski, D.6
Schönfisch, B.7
Guiard, B.8
Sickmann, A.9
Pfanner, N.10
Meisinger, C.11
-
37
-
-
22244446505
-
The mammalian unfolded protein response
-
M. Schröder, and R.J. Kaufman The mammalian unfolded protein response Annu. Rev. Biochem. 74 2005 739 789
-
(2005)
Annu. Rev. Biochem.
, vol.74
, pp. 739-789
-
-
Schröder, M.1
Kaufman, R.J.2
-
38
-
-
84876991539
-
Stress-independent activation of XBP1s and/or ATF6 reveals three functionally diverse ER proteostasis environments
-
M.D. Shoulders, L.M. Ryno, J.C. Genereux, J.J. Moresco, P.G. Tu, C. Wu, J.R. Yates III, A.I. Su, J.W. Kelly, and R.L. Wiseman Stress-independent activation of XBP1s and/or ATF6 reveals three functionally diverse ER proteostasis environments Cell Rep 3 2013 1279 1292
-
(2013)
Cell Rep
, vol.3
, pp. 1279-1292
-
-
Shoulders, M.D.1
Ryno, L.M.2
Genereux, J.C.3
Moresco, J.J.4
Tu, P.G.5
Wu, C.6
Yates III, J.R.7
Su, A.I.8
Kelly, J.W.9
Wiseman, R.L.10
-
39
-
-
70350064588
-
Protein quality control in mitochondria
-
T. Tatsuta Protein quality control in mitochondria J. Biochem. 146 2009 455 461
-
(2009)
J. Biochem.
, vol.146
, pp. 455-461
-
-
Tatsuta, T.1
-
40
-
-
3843117589
-
Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells
-
K.M. Vattem, and R.C. Wek Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells Proc. Natl. Acad. Sci. USA 101 2004 11269 11274
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 11269-11274
-
-
Vattem, K.M.1
Wek, R.C.2
-
41
-
-
0035106351
-
Large-scale analysis of the yeast proteome by multidimensional protein identification technology
-
M.P. Washburn, D. Wolters, and J.R. Yates III Large-scale analysis of the yeast proteome by multidimensional protein identification technology Nat. Biotechnol. 19 2001 242 247
-
(2001)
Nat. Biotechnol.
, vol.19
, pp. 242-247
-
-
Washburn, M.P.1
Wolters, D.2
Yates III, J.R.3
-
42
-
-
35848935017
-
Translational control and the unfolded protein response
-
R.C. Wek, and D.R. Cavener Translational control and the unfolded protein response Antioxid. Redox Signal. 9 2007 2357 2371
-
(2007)
Antioxid. Redox Signal.
, vol.9
, pp. 2357-2371
-
-
Wek, R.C.1
Cavener, D.R.2
-
43
-
-
32544446451
-
Coping with stress: EIF2 kinases and translational control
-
R.C. Wek, H.Y. Jiang, and T.G. Anthony Coping with stress: eIF2 kinases and translational control Biochem. Soc. Trans. 34 2006 7 11
-
(2006)
Biochem. Soc. Trans.
, vol.34
, pp. 7-11
-
-
Wek, R.C.1
Jiang, H.Y.2
Anthony, T.G.3
-
44
-
-
4544253996
-
Ultraviolet light activates NFkappaB through translational inhibition of IkappaBalpha synthesis
-
S. Wu, M. Tan, Y. Hu, J.L. Wang, D. Scheuner, and R.J. Kaufman Ultraviolet light activates NFkappaB through translational inhibition of IkappaBalpha synthesis J. Biol. Chem. 279 2004 34898 34902
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 34898-34902
-
-
Wu, S.1
Tan, M.2
Hu, Y.3
Wang, J.L.4
Scheuner, D.5
Kaufman, R.J.6
-
45
-
-
67651173106
-
Proteomics by mass spectrometry: Approaches, advances, and applications
-
J.R. Yates, C.I. Ruse, and A. Nakorchevsky Proteomics by mass spectrometry: approaches, advances, and applications Annu. Rev. Biomed. Eng. 11 2009 49 79
-
(2009)
Annu. Rev. Biomed. Eng.
, vol.11
, pp. 49-79
-
-
Yates, J.R.1
Ruse, C.I.2
Nakorchevsky, A.3
-
46
-
-
0037009521
-
A mitochondrial specific stress response in mammalian cells
-
Q. Zhao, J. Wang, I.V. Levichkin, S. Stasinopoulos, M.T. Ryan, and N.J. Hoogenraad A mitochondrial specific stress response in mammalian cells EMBO J. 21 2002 4411 4419
-
(2002)
EMBO J.
, vol.21
, pp. 4411-4419
-
-
Zhao, Q.1
Wang, J.2
Levichkin, I.V.3
Stasinopoulos, S.4
Ryan, M.T.5
Hoogenraad, N.J.6
|