-
1
-
-
73949145041
-
The potential of biologic network models in understanding the etiopathogenesis of ovarian cancer
-
KHALIL I, BREWER MA, NEYARAPALLY T, RUNOWICZ CD. The potential of biologic network models in understanding the etiopathogenesis of ovarian cancer. Gynecol Oncol 2010;116:282-285.
-
(2010)
Gynecol Oncol
, vol.116
, pp. 282-285
-
-
Khalil, I.1
Brewer, M.A.2
Neyarapally, T.3
Runowicz, C.D.4
-
2
-
-
58149489177
-
Ovarian carcinoma subtypes are different diseases: Implications for biomarker studies
-
KÖBEL M, KALLOGER SE, BOYD N, MCKINNEY S, MEHL E, PALMER C, LEUNG S, BOWEN NJ, IONESCU DN, RAJPUT A, PRENTICE LM, MILLER D, SANTOS J, SWENERTON K, GILKS CB, HUNTSMAN D. Ovarian carcinoma subtypes are different diseases: Implications for biomarker studies. PLoS Med 2008;5:1749-1760.
-
(2008)
PLoS Med
, vol.5
, pp. 1749-1760
-
-
Köbel, M.1
Kalloger, S.E.2
Boyd, N.3
McKinney, S.4
Mehl, E.5
Palmer, C.6
Leung, S.7
Bowen, N.J.8
Ionescu, D.N.9
Rajput, A.10
Prentice, L.M.11
Miller, D.12
Santos, J.13
Swenerton, K.14
Gilks, C.B.15
Huntsman, D.16
-
4
-
-
0033936074
-
Ovarian cancer: Epidemiology, biology, and prognostic factors
-
HOLSCHNEIDER C, BEREK J. Ovarian cancer: epidemiology, biology, and prognostic factors. Semin Surg Oncol 2000;19:3-10.
-
(2000)
Semin Surg Oncol
, vol.19
, pp. 3-10
-
-
Holschneider, C.1
Berek, J.2
-
5
-
-
77955424794
-
Current clinical use of biomarkers for epithelial ovarian cancer
-
MOORE R, MACLAUGHLIN S. Current clinical use of biomarkers for epithelial ovarian cancer. Curr Opin Oncol 2010;22:492-497.
-
(2010)
Curr Opin Oncol
, vol.22
, pp. 492-497
-
-
Moore, R.1
MacLaughlin, S.2
-
6
-
-
77951623830
-
Integrating high-throughput technologies in the quest for effective biomarkers for ovarian cancer
-
KULASINGAM V, PAVLOU M P, DIAMANDIS EP. Integrating high-throughput technologies in the quest for effective biomarkers for ovarian cancer. Nat Rev 2010;10:371-378.
-
(2010)
Nat Rev
, vol.10
, pp. 371-378
-
-
Kulasingam, V.1
Pavlou, M.P.2
Diamandis, E.P.3
-
7
-
-
39749190698
-
Diagnostic markers for early detection of ovarian cancer
-
VISINTIN I, FENG Z, LONGTON G, WARD DC, ALVERO AB, LAI Y, TENTHOREY J, LEISER A, FLORES-SAAIB R, YU H, AZORI M, RUTHERFORD T, SCHWARTZ PE, MOR G. Diagnostic markers for early detection of ovarian cancer. Clin Cancer Res 2008;14:1065-1072.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 1065-1072
-
-
Visintin, I.1
Feng, Z.2
Longton, G.3
Ward, D.C.4
Alvero, A.B.5
Lai, Y.6
Tenthorey, J.7
Leiser, A.8
Flores-Saaib, R.9
Yu, H.10
Azori, M.11
Rutherford, T.12
Schwartz, P.E.13
Mor, G.14
-
8
-
-
33947512381
-
An integrated genomic-based approach to individualized treatment of patients with advanced stage ovarian cancer
-
DRESSMAN HK, BERCHUCK A, CHAN G, ZHAI J, BILD A, SAYER R, CRAGUN J, CLARKE J, WHITAKER RS, LI L, GRAY J, MARKS J, GINSBURG GS, POTTI A, WEST M, NEVINS JR, LANCASTER JM. An integrated genomic-based approach to individualized treatment of patients with advanced stage ovarian cancer. J Clin Oncol 2007;25:517-525.
-
(2007)
J Clin Oncol
, vol.25
, pp. 517-525
-
-
Dressman, H.K.1
Berchuck, A.2
Chan, G.3
Zhai, J.4
Bild, A.5
Sayer, R.6
Cragun, J.7
Clarke, J.8
Whitaker, R.S.9
Li, L.10
Gray, J.11
Marks, J.12
Ginsburg, G.S.13
Potti, A.14
West, M.15
Nevins, J.R.16
Lancaster, J.M.17
-
9
-
-
0035189634
-
Intraperitoneal cisplatin-based chemotherapy vs.intravenous cisplatin-based chemotherapy for stage III optimally cytoreduced epithelial ovarian cancer
-
YEN MS, JUANG CM, LAI CR, CHAO GC, NG HT, YUAN CC. Intraperitoneal cisplatin-based chemotherapy vs.intravenous cisplatin-based chemotherapy for stage III optimally cytoreduced epithelial ovarian cancer. Int J Gynaecol Obstet 2001;72:55-60.
-
(2001)
Int J Gynaecol Obstet
, vol.72
, pp. 55-60
-
-
Yen, M.S.1
Juang, C.M.2
Lai, C.R.3
Chao, G.C.4
Ng, H.T.5
Yuan, C.C.6
-
10
-
-
77950497098
-
Chemotherapy: Current drugs still have potential in advanced ovarian cancer
-
HOGBERG T. Chemotherapy: current drugs still have potential in advanced ovarian cancer. Nat Rev Clin Oncol 2010;7:191-193.
-
(2010)
Nat Rev Clin Oncol
, vol.7
, pp. 191-193
-
-
Hogberg, T.1
-
11
-
-
77950355502
-
Pharmacogenomics of Taxane/Platinum therapy in ovarian cancer
-
MARSH S. Pharmacogenomics of Taxane/Platinum therapy in ovarian cancer. Int J Gynecol Cancer 2009;2:30-34.
-
(2009)
Int J Gynecol Cancer
, vol.2
, pp. 30-34
-
-
Marsh, S.1
-
12
-
-
84859771379
-
Molecular mechanisms of cisplatin resistance
-
GALLUZZI L, SENOVILLA L, VITALE I, MICHELS J, MARTINS I, KEPP O, CASTEDO M, KROEMER G. Molecular mechanisms of cisplatin resistance. Oncogene 2012;31:1869-1883.
-
(2012)
Oncogene
, vol.31
, pp. 1869-1883
-
-
Galluzzi, L.1
Senovilla, L.2
Vitale, I.3
Michels, J.4
Martins, I.5
Kepp, O.6
Castedo, M.7
Kroemer, G.8
-
14
-
-
34247862218
-
Gene expression response to cisplatin treatment in drug-sensitive and drug-resistant ovarian cancer cells
-
LI J, WOOD WH, BECKER KG, WEERARATNA AT, MORIN PJ. Gene expression response to cisplatin treatment in drug-sensitive and drug-resistant ovarian cancer cells. Oncogene 2007;26:2860-2872.
-
(2007)
Oncogene
, vol.26
, pp. 2860-2872
-
-
Li, J.1
Wood, W.H.2
Becker, K.G.3
Weeraratna, A.T.4
Morin, P.J.5
-
15
-
-
33744485827
-
Identification of genes whose expression is associated with cisplatin resistance in human ovarian carcinoma cells
-
CHENG TC, MANOREK G, SAMIMI G, LIN X, BERRY CC, HOWELL SB. Identification of genes whose expression is associated with cisplatin resistance in human ovarian carcinoma cells. Cancer Chemother Pharmacol 2006;58:384-395.
-
(2006)
Cancer Chemother Pharmacol
, vol.58
, pp. 384-395
-
-
Cheng, T.C.1
Manorek, G.2
Samimi, G.3
Lin, X.4
Berry, C.C.5
Howell, S.B.6
-
16
-
-
77949712722
-
Platinum-DNA interactions and subsequent cellular processes controlling sensitivity to anticancer platinum complexes
-
AHMAD S. Platinum-DNA interactions and subsequent cellular processes controlling sensitivity to anticancer platinum complexes. Chem Biodivers 2010;7:543-566.
-
(2010)
Chem Biodivers
, vol.7
, pp. 543-566
-
-
Ahmad, S.1
-
17
-
-
79951952653
-
Drug transporters of platinum-based anticancer agents and their clinical significance
-
BURGER H, LOOS WJ, EECHOUTE K, VERWEIJ J, MATHIJSSEN RH, WIEMER EA. Drug transporters of platinum-based anticancer agents and their clinical significance. Drug Resist Update 2011;14:22-34.
-
(2011)
Drug Resist Update
, vol.14
, pp. 22-34
-
-
Burger, H.1
Loos, W.J.2
Eechoute, K.3
Verweij, J.4
Mathijssen, R.H.5
Wiemer, E.A.6
-
19
-
-
0035190026
-
Cellular function of phosphoinosi-tide 3-kinases: Implications for development, homeostasis, and cancer
-
KATSO R, OKKENHAUG K, AHMADI K, WHITE S, TIMMS J, WATERFIELD MD. Cellular function of phosphoinosi-tide 3-kinases: implications for development, homeostasis, and cancer. Annu Rev Cell Dev Biol 2001;17:615-675.
-
(2001)
Annu Rev Cell Dev Biol
, vol.17
, pp. 615-675
-
-
Katso, R.1
Okkenhaug, K.2
Ahmadi, K.3
White, S.4
Timms, J.5
Waterfield, M.D.6
-
20
-
-
0142227019
-
Targeting the PI3K-Akt pathway in human cancer: Rationale and promise
-
LUO J, MANNING BD, CANTLEY LC. Targeting the PI3K-Akt pathway in human cancer: rationale and promise. Cancer Cell 2003;4:257-262.
-
(2003)
Cancer Cell
, vol.4
, pp. 257-262
-
-
Luo, J.1
Manning, B.D.2
Cantley, L.C.3
-
21
-
-
0036968347
-
Activation of the PI3K/Akt pathway and chemotherapeutic resistance
-
WEST KA, CASTILLO SS, DENNIS PA. Activation of the PI3K/Akt pathway and chemotherapeutic resistance. Drug Resist Updat 2002;5:234-248.
-
(2002)
Drug Resist Updat
, vol.5
, pp. 234-248
-
-
West, K.A.1
Castillo, S.S.2
Dennis, P.A.3
-
22
-
-
0036185848
-
The protein kinase B/Akt signalling pathway in human malignancy
-
NICHOLSON KM, ANDERSON NG. The protein kinase B/Akt signalling pathway in human malignancy. Cell Signal 2002;14:381-395.
-
(2002)
Cell Signal
, vol.14
, pp. 381-395
-
-
Nicholson, K.M.1
Anderson, N.G.2
-
23
-
-
0036632368
-
The phosphatidylinositol 3-kinase Akt pathway in human cancer
-
VIVANCO I, SAWYERS CL. The phosphatidylinositol 3-kinase Akt pathway in human cancer. Nat Rev Cancer 2002;2:489-501.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 489-501
-
-
Vivanco, I.1
Sawyers, C.L.2
-
24
-
-
0034742120
-
Akt1/PKBalpha kinase is frequently elevated in human cancers and its constitutive activation is required for oncogenic trans-formation in NIH3T3 cells
-
SUN M, WANG G, PACIGA JE, FELDMAN RI, YUAN ZQ, MA XL, SHELLEY SA, JOVE R, TSICHLIS PN, NICOSIA S V, CHENG JQ. Akt1/PKBalpha kinase is frequently elevated in human cancers and its constitutive activation is required for oncogenic trans-formation in NIH3T3 cells. Am J Pathol 2001;159:431-437.
-
(2001)
Am J Pathol
, vol.159
, pp. 431-437
-
-
Sun, M.1
Wang, G.2
Paciga, J.E.3
Feldman, R.I.4
Yuan, Z.Q.5
Ma, X.L.6
Shelley, S.A.7
Jove, R.8
Tsichlis, P.N.9
Nicosia, S.V.10
Cheng, J.Q.11
-
25
-
-
0028217223
-
Wortmannin, a potent and selective inhibitor of phosphatidylinositol-3-kinase
-
POWIS G, BONJOUKLIAN R, BERGGREN MM, GALLEGOS A, ABRAHAM R, ASHENDEL C, ZALKOW L, MATTER W F, DODGE J, GRINDEY G. Wortmannin, a potent and selective inhibitor of phosphatidylinositol-3-kinase. Cancer Res 1994;54:2419-2423.
-
(1994)
Cancer Res
, vol.54
, pp. 2419-2423
-
-
Powis, G.1
Bonjouklian, R.2
Berggren, M.M.3
Gallegos, A.4
Abraham, R.5
Ashendel, C.6
Zalkow, L.7
Matter, W.F.8
Dodge, J.9
Grindey, G.10
-
26
-
-
0028963084
-
Requirement for phosphatidyli-nositol 3-kinase in the prevention of apoptosis by nerve growth factor
-
YAO R, COOPER GM. Requirement for phosphatidyli-nositol 3-kinase in the prevention of apoptosis by nerve growth factor. Nature (Lond.) 1995;267:2003-2006.
-
(1995)
Nature (Lond.)
, vol.267
, pp. 2003-2006
-
-
Yao, R.1
Cooper, G.M.2
-
27
-
-
84879311819
-
Akt activation protects liver cells from apoptosis in rats during acute cold exposure
-
WANG J, CHEN Y, ZHANG W, ZHENG G, MENG S, CHE H, KE T, YANG J, CHEN J, LUO W. Akt activation protects liver cells from apoptosis in rats during acute cold exposure. Int J Biol Sci 2013;9:509-517.
-
(2013)
Int J Biol Sci
, vol.9
, pp. 509-517
-
-
Wang, J.1
Chen, Y.2
Zhang, W.3
Zheng, G.4
Meng, S.5
Che, H.6
Ke, T.7
Yang, J.8
Chen, J.9
Luo, W.10
-
28
-
-
84866113885
-
Wortman-nin inhibits proliferation and induces apoptosis of MCF-7 breast cancer cells
-
YUN J, LV YG, YAO Q, WANG L, LI Y P, YI J. Wortman-nin inhibits proliferation and induces apoptosis of MCF-7 breast cancer cells. Eur J Gynaecol Oncol 2012;33:367-369.
-
(2012)
Eur J Gynaecol Oncol
, vol.33
, pp. 367-369
-
-
Yun, J.1
Lv, Y.G.2
Yao, Q.3
Wang, L.4
Li, Y.P.5
Yi, J.6
-
29
-
-
34250022167
-
Enhancement of tumor radioresponse by wortmannin in C3H/HeJ hepatocarcinoma
-
KIM W, SEONG J, AN JH, OH HJ. Enhancement of tumor radioresponse by wortmannin in C3H/HeJ hepatocarcinoma. J Radiat Res 2007;48:187-195.
-
(2007)
J Radiat Res
, vol.48
, pp. 187-195
-
-
Kim, W.1
Seong, J.2
An, J.H.3
Oh, H.J.4
-
30
-
-
79959844133
-
Differentially expressed genes associated with cisplatin resistance in human ovarian adenocarcinoma cell line A2780
-
SOLAR P, SYTKOWSKI AJ. Differentially expressed genes associated with cisplatin resistance in human ovarian adenocarcinoma cell line A2780. Cancer Lett 2011;309:11-18.
-
(2011)
Cancer Lett
, vol.309
, pp. 11-18
-
-
Solar, P.1
Sytkowski, A.J.2
-
31
-
-
0036633164
-
Constitutive and inducible Akt activity promotes resistance to chemotherapy, trastuzumab, or tamoxifen in breast cancer cells
-
CLARK AS, WEST K, STREICHER S, DENNIS PA. Constitutive and inducible Akt activity promotes resistance to chemotherapy, trastuzumab, or tamoxifen in breast cancer cells. Mol Cancer Ther 2012;1:707-717.
-
(2012)
Mol Cancer Ther
, vol.1
, pp. 707-717
-
-
Clark, A.S.1
West, K.2
Streicher, S.3
Dennis, P.A.4
-
32
-
-
0034027514
-
Overexpression of Akt/Akt can modulate chemotherapy-induced apoptosis
-
PAGE C, LIN HJ, JIN Y, CASTLE V P, NUNEZ G, HUANG M, LIN J. Overexpression of Akt/Akt can modulate chemotherapy-induced apoptosis. Anticancer Res 2010;20:407-416.
-
(2010)
Anticancer Res
, vol.20
, pp. 407-416
-
-
Page, C.1
Lin, H.J.2
Jin, Y.3
Castle, V.P.4
Nunez, G.5
Huang, M.6
Lin, J.7
-
33
-
-
33645504968
-
Inhibition of phosphatidylinositol 3-kinase increases efficacy of cisplatin in in vivo ovarian cancer models
-
OHTA T, OHMICHI M, HAYASAKA T, MABUCHI S, SAITOH M, KAWAGOE J, TAKAHASHI K, IGARASHI H, DU B, DOSHIDA M, MIREI IG, MOTOYAMA T, TASAKA K, KURACHI H. Inhibition of phosphatidylinositol 3-kinase increases efficacy of cisplatin in in vivo ovarian cancer models. Endocrinology 2006;147:1761-1769.
-
(2006)
Endocrinology
, vol.147
, pp. 1761-1769
-
-
Ohta, T.1
Ohmichi, M.2
Hayasaka, T.3
Mabuchi, S.4
Saitoh, M.5
Kawagoe, J.6
Takahashi, K.7
Igarashi, H.8
Du, B.9
Doshida, M.10
Mirei, I.G.11
Motoyama, T.12
Tasaka, K.13
Kurachi, H.14
-
34
-
-
0032527913
-
AKT2, a member of the protein kinase B family, is activated by growth factors, v-Ha-ras, and v-src through phosphatidylinositol 3-kinase in human ovarian epithelial cancer cells
-
LIU AX, TESTA JR, HAMILTON TC, JOVE R, NICOSIA S V, CHENG JQ. AKT2, a member of the protein kinase B family, is activated by growth factors, v-Ha-ras, and v-src through phosphatidylinositol 3-kinase in human ovarian epithelial cancer cells. Cancer Res 1998;58:2973-2977.
-
(1998)
Cancer Res
, vol.58
, pp. 2973-2977
-
-
Liu, A.X.1
Testa, J.R.2
Hamilton, T.C.3
Jove, R.4
Nicosia, S.V.5
Cheng, J.Q.6
-
35
-
-
0034326803
-
Inhibition of BAD phosphorylation either at serine 112 via extracellular signal-regulated protein kinase cascade or at serine 136 via Akt cascade sensitizes human ovarian cancer cells to cisplatin
-
HAYAKAWA J, OHMICHI M, KURACHI H, KANDA Y, HISAMOTO K, NISHIO Y, ADACHI K, TASAKA K, KANZAKI T, MURATA Y. Inhibition of BAD phosphorylation either at serine 112 via extracellular signal-regulated protein kinase cascade or at serine 136 via Akt cascade sensitizes human ovarian cancer cells to cisplatin. Cancer Res 2000;60:5988-5994.
-
(2000)
Cancer Res
, vol.60
, pp. 5988-5994
-
-
Hayakawa, J.1
Ohmichi, M.2
Kurachi, H.3
Kanda, Y.4
Hisamoto, K.5
Nishio, Y.6
Adachi, K.7
Tasaka, K.8
Kanzaki, T.9
Murata, Y.10
-
36
-
-
0029156587
-
In vitro and in vivo antitumor activity of the phosphatidylinositol-3-kinase inhibitor, wortmannin
-
SCHULTZ RM, MERRIMAN RL, ANDIS SL, BONJOUKLIAN R, GRINDEY GB, RUTHERFORD PG, GALLEGOS A, MASSEY K, POWIS G. In vitro and in vivo antitumor activity of the phosphatidylinositol-3-kinase inhibitor, wortmannin. Anticancer Res 1995;15:1135-1139.
-
(1995)
Anticancer Res
, vol.15
, pp. 1135-1139
-
-
Schultz, R.M.1
Merriman, R.L.2
Andis, S.L.3
Bonjouklian, R.4
Grindey, G.B.5
Rutherford, P.G.6
Gallegos, A.7
Massey, K.8
Powis, G.9
|