N-acetyl cysteine improves the effects of corticosteroids in a mouse model of chlorine-induced acute lung injury

Toxicology

Volumn 328, Issue , 2015, Pages 40-47

  Wigenstam, Elisabeth ^a   Koch, Bo ^a   Bucht, Anders ^a,b   Jonasson, Sofia ^a  

^a SWEDISH DEFENCE RESEARCH AGENCY   (Sweden)

^b UMEÅ UNIVERSITY   (Sweden)

Author keywords

Airway hyperresponsiveness; Chemical induced lung injury; Chlorine; Corticosteroids; Respiratory mechanics

Indexed keywords

ACETYLCYSTEINE; CHLORINE; DEXAMETHASONE; FIBRINOGEN; PLASMINOGEN ACTIVATOR INHIBITOR 1; REPARIXIN; ROLIPRAM; TRIPTOLIDE; ANTIINFLAMMATORY AGENT; ANTIOXIDANT; CORTICOSTEROID; GAS;

ACUTE LUNG INJURY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG EXPOSURE; DRUG MEGADOSE; FEMALE; INFLAMMATORY CELL; LOW DRUG DOSE; LUNG INJURY; LUNG LAVAGE; MOUSE; NONHUMAN; SERUM; ANIMAL; BAGG ALBINO MOUSE; BLOOD; BRONCHIAL HYPERREACTIVITY; CELL PROTECTION; CHEMICALLY INDUCED; CYTOLOGY; DISEASE MODEL; DRUG COMBINATION; DRUG EFFECTS; DRUG POTENTIATION; EXPOSURE; GAS; IMMUNOLOGY; LUNG; METABOLISM; NEUTROPHIL CHEMOTAXIS; PATHOPHYSIOLOGY; TIME;

MUS;

ACETYLCYSTEINE; ACUTE LUNG INJURY; ADRENAL CORTEX HORMONES; ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIOXIDANTS; BRONCHIAL HYPERREACTIVITY; BRONCHOALVEOLAR LAVAGE FLUID; CHLORINE; CYTOPROTECTION; DEXAMETHASONE; DISEASE MODELS, ANIMAL; DRUG SYNERGISM; DRUG THERAPY, COMBINATION; FEMALE; FIBRINOGEN; GASES; INHALATION EXPOSURE; LUNG; MICE, INBRED BALB C; NEUTROPHIL INFILTRATION; PLASMINOGEN ACTIVATOR INHIBITOR 1; TIME FACTORS;

EID: 84919935104     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2014.12.008     Document Type: Article

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