Amyloid precursor protein at node of Ranvier modulates nodal formation

Cell Adhesion and Migration

Volumn 8, Issue 4, 2014, Pages 396-403

  Xu, De En ^a   Zhang, Wen Min ^a   Yang, Zara Zhuyun ^b,c   Zhu, Hong Mei ^b,c   Yan, Ke ^a   Li, Shao ^b,d   Bagnard, Dominique ^e   Dawe, Gavin S ^f,g,h   Ma, Quan Hong ^a   Xiao, Zhi Cheng ^b,c  

^a SOOCHOW UNIVERSITY   (China)

^b KUNMING MEDICAL UNIVERSITY   (China)

^c MONASH UNIVERSITY   (Australia)

^d DALIAN MEDICAL UNIVERSITY   (China)

^e UNIVERSITÉ DE STRASBOURG   (France)

^f SINAPSE Singapore Institute for Neurotechnology   (Singapore)

^g NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^h NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

APP; Myelination; Nodes of Ranvier; Paranode; Sodium channels

Indexed keywords

AMYLOID PRECURSOR PROTEIN; POTASSIUM CHANNEL; PROTEIN AGGREGATE; SODIUM CHANNEL; TENASCIN; TENASCIN R; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CENTRAL NERVOUS SYSTEM; KNOCKOUT MOUSE; MOUSE; MYELINATION; NERVE FIBER; NONHUMAN; OBSERVATIONAL STUDY; PERIPHERAL NERVOUS SYSTEM; PROTEIN EXPRESSION; RANVIER NODE; SCIATIC NERVE; SPINAL CORD; TRANSGENIC MOUSE; ANIMAL; DEMYELINATING DISEASE; GENETICS; METABOLISM; MYELIN SHEATH; PHYSIOLOGY;

MUS;

AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; AXONS; CENTRAL NERVOUS SYSTEM; DEMYELINATING DISEASES; MICE; MICE, KNOCKOUT; MYELIN SHEATH; PERIPHERAL NERVOUS SYSTEM; RANVIER'S NODES; SCIATIC NERVE; SODIUM CHANNELS; SPINAL CORD; TENASCIN;

EID: 84919921231     PISSN: 19336918     EISSN: 19336926     Source Type: Journal    
DOI: 10.4161/cam.28802     Document Type: Article

References (46)

1. Noble M. The possible role of myelin destruction as a precipitating event in Alzheimer's disease. Neurobiol Aging 2004;25:25-31; PMID:14675726; http://dx. doi.org/10.1016/j.neurobiolaging.2003.07.001
2. Bartzokis G. Age-related myelin breakdown: a developmental model of cognitive decline and Alzheimer's disease. Neurobiol Aging 2004;25:5-18, author reply 49-62; PMID:14675724; http://dx.doi.org/10.1016/j. neurobiolaging.2003.03.001
3. Bartzokis G. Alzheimer's disease as homeostatic responses to age-related myelin breakdown. Neurobiol Aging 2011;32:1341-71; PMID:19775776; http://dx. doi.org/10.1016/j.neurobiolaging.2009.08.007
4. Fieremans E, Benitez A, Jensen JH, Falangola MF, Tabesh A, Deardorff RL, Spampinato MV, Babb JS, Novikov DS, Ferris SH, et al. Novel white matter tract integrity metrics sensitive to Alzheimer disease progression. AJNR Am J Neuroradiol 2013;34:2105-12; PMID:23764722; http://dx.doi.org/10.3174/ajnr. A3553
5. Schmued LC, Raymick J, Paule MG, Dumas M, Sarkar S. Characterization of myelin pathology in the hippocampal complex of a transgenic mouse model of Alzheimer's disease. Curr Alzheimer Res 2013;10:30-7; PMID:23157338
6. Selkoe DJ. American College of Physicians; American Physiological Society. Alzheimer disease: mechanistic understanding predicts novel therapies. Ann Intern Med 2004;140:627-38; PMID:15096334; http://dx. doi.org/10.7326/0003-4819-140-8-200404200-00010
7. Coleman M. Axon degeneration mechanisms: commonality amid diversity. Nat Rev Neurosci 2005;6:889-98; PMID:16224497; http://dx.doi.org/10.1038/nrn1788
8. Dutta R, Chang A, Doud MK, Kidd GJ, Ribaudo MV, Young EA, Fox RJ, Staugaitis SM, Trapp BD. Demyelination causes synaptic alterations in hippocampi from multiple sclerosis patients. Ann Neurol 2011;69:445-54; PMID:21446020; http://dx.doi.org/10.1002/ana.22337
9. Ferguson B, Matyszak MK, Esiri MM, Perry VH. Axonal damage in acute multiple sclerosis lesions. Brain 1997;120:393-9; PMID:9126051; http://dx.doi.org/10.1093/brain/120.3.393
10. Salzer JL. Polarized domains of myelinated axons. Neuron 2003;40:297-318; PMID:14556710; http://dx. doi.org/10.1016/S0896-6273 (03) 00628-7
11. Ma QH, Yang WL, Nie DY, Dawe GS, Xiao ZC. Physiological roles of neurite outgrowth inhibitors in myelinated axons of the central nervous system-implications for the therapeutic neutralization of neurite outgrowth inhibitors. Curr Pharm Des 2007;13:2529-37; PMID:17692021; http://dx.doi.org/10.2174/138161207781368602
12. Rasband MN, Trimmer JS, Schwarz TL, Levinson SR, Ellisman MH, Schachner M, Shrager P. Potassium channel distribution, clustering, and function in remyelinating rat axons. J Neurosci 1998;18:36-47; PMID:9412484
13. Weber P, Bartsch U, Rasband MN, Czaniera R, Lang Y, Bluethmann H, Margolis RU, Levinson SR, Shrager P, Montag D, et al. Mice deficient for tenascin-R display alterations of the extracellular matrix and decreased axonal conduction velocities in the CNS. J Neurosci 1999;19:4245-62; PMID:10341229
14. Alvarez J, Moreno RD, Llanos O, Inestrosa NC, Brandan E, Colby T, Esch FS. Axonal sprouting induced in the sciatic nerve by the amyloid precursor protein (APP) and other antiproteases. Neurosci Lett. 1992;144(1-2):130-4.
15. Puglielli L, Konopka G, Pack-Chung E, Ingano LA, Berezovska O, Hyman BT, Chang TY, Tanzi RE, Kovacs DM. Acyl-coenzyme A: cholesterol acyltransferase modulates the generation of the amyloid beta-peptide. Nat Cell Biol 2001;3:905-12; PMID:11584272; http://dx.doi.org/10.1038/ncb1001-905
16. Saura CA, Chen G, Malkani S, Choi SY, Takahashi RH, Zhang D, Gouras GK, Kirkwood A, Morris RG, Shen J. Conditional inactivation of presenilin 1 prevents amyloid accumulation and temporarily rescues contextual and spatial working memory impairments in amyloid precursor protein transgenic mice. J Neurosci 2005;25:6755-64; PMID:16033885; http://dx.doi.org/10.1523/JNEUROSCI.1247-05.2005
17. Ma QH, Futagawa T, Yang WL, Jiang XD, Zeng L, Takeda Y, Xu RX, Bagnard D, Schachner M, Furley AJ, et al. A TAG1-APP signalling pathway through Fe65 negatively modulates neurogenesis. Nat Cell Biol 2008;10:283-94; PMID:18278038; http://dx.doi.org/10.1038/ncb1690
18. Young-Pearse TL, Bai J, Chang R, Zheng JB, Lo Turco JJ, Selkoe DJ. A critical function for beta-amyloid precursor protein in neuronal migration revealed by in utero RNA interference. J Neurosci 2007;27:14459-69; PMID:18160654; http://dx.doi.org/10.1523/JNEUROSCI.4701-07.2007
19. Kazarinova-Noyes K, Malhotra JD, McEwen DP, Mattei LN, Berglund EO, Ranscht B, Levinson SR, Schachner M, Shrager P, Isom LL, et al. Contactin associates with NaC channels and increases their functional expression. J Neurosci 2001;21:7517-25; PMID: 11567041
20. Huber AB, Weinmann O, Brösamle C, Oertle T, Schwab ME. Patterns of Nogo mRNA and protein expression in the developing and adult rat and after CNS lesions. J Neurosci 2002;22:3553-67; PMID:11978832
21. Hodgkin AL, Huxley AF. A quantitative description of membrane current and its application to conduction and excitation in nerve. J Physiol 1952;117:500-44; PMID:12991237
22. Pedraza L, Huang JK, Colman DR. Organizing principles of the axoglial apparatus. Neuron 2001;30:335-44; PMID:11394997; http://dx.doi.org/10.1016/S0896-6273 (01) 00306-3
23. Hille B. Ion channels of excitable membranes, 3d ed. Scitech Book News. Portland: Book News, Inc., 2001.
24. Susuki K, Rasband MN. Molecular mechanisms of node of Ranvier formation. Curr Opin Cell Biol 2008;20:616-23; PMID:18929652; http://dx.doi.org/10.1016/j.ceb.2008.09.007
25. Hsiao KK, Borchelt DR, Olson K, Johannsdottir R, Kitt C, Yunis W, Xu S, Eckman C, Younkin S, Price D, et al. Age-related CNS disorder and early death in transgenic FVB/N mice overexpressing Alzheimer amyloid precursor proteins. Neuron 1995;15:1203-18; PMID:7576662; http://dx.doi.org/10.1016/0896-6273 (95) 90107-8
26. Michailov GV, Sereda MW, Brinkmann BG, Fischer TM, Haug B, Birchmeier C, Role L, Lai C, Schwab MH, Nave KA. Axonal neuregulin-1 regulates myelin sheath thickness. Science 2004;304:700-3; PMID: 15044753; http://dx.doi.org/10.1126/science.1095862
27. Traka M, Dupree JL, Popko B, Karagogeos D. The neuronal adhesion protein TAG-1 is expressed by Schwann cells and oligodendrocytes and is localized to the juxtaparanodal region of myelinated fibers. J Neurosci 2002;22:3016-24; PMID:11943804
28. Poliak S, Salomon D, Elhanany H, Sabanay H, Kiernan B, Pevny L, Stewart CL, Xu X, Chiu SY, Shrager P, et al. Juxtaparanodal clustering of Shaker-like KC channels in myelinated axons depends on Caspr2 and TAG-1. J Cell Biol 2003;162:1149-60; PMID:12963709; http://dx. doi.org/10.1083/jcb.200305018
29. Poliak S, Peles E. The local differentiation of myelinated axons at nodes of Ranvier. Nat Rev Neurosci 2003;4:968-80; PMID:14682359; http://dx.doi.org/10.1038/nrn1253
30. McEwen DP, Isom LL. Heterophilic interactions of sodium channel beta1 subunits with axonal and glial cell adhesion molecules. J Biol Chem 2004;279:52744-52; PMID:15466474; http://dx.doi.org/10.1074/jbc. M405990200
31. Breen KC, Bruce M, Anderton BH. Beta amyloid precursor protein mediates neuronal cell-cell and cell-surface adhesion. J Neurosci Res 1991;28:90-100; PMID:1645774; http://dx.doi.org/10.1002/jnr.490280109
32. Yamazaki T, Koo EH, Selkoe DJ. Cell surface amyloid beta-protein precursor colocalizes with beta 1 integrins at substrate contact sites in neural cells. J Neurosci 1997;17:1004-10; PMID:8994055
33. Annaert WG, Esselens C, Baert V, Boeve C, Snellings G, Cupers P, Craessaerts K, De Strooper B. Interaction with telencephalin and the amyloid precursor protein predicts a ring structure for presenilins. Neuron 2001;32:579-89; PMID:11719200; http://dx.doi.org/10.1016/S0896-6273 (01) 00512-8
34. Craner MJ, Newcombe J, Black JA, Hartle C, Cuzner ML, Waxman SG. Molecular changes in neurons in multiple sclerosis: altered axonal expression of Nav1.2 and Nav1.6 sodium channels and NaC/Ca2 Cexchanger. Proc Natl Acad Sci U S A 2004;101:8168-73; PMID:15148385; http://dx.doi.org/10.1073/pnas.0402765101
35. Craner MJ, Hains BC, Lo AC, Black JA, Waxman SG. Co-localization of sodium channel Nav1.6 and the sodium-calcium exchanger at sites of axonal injury in the spinal cord in EAE. Brain 2004;127:294-303; PMID:14662515; http://dx.doi.org/10.1093/brain/awh032
36. Siman R, Card JP, Nelson RB, Davis LG. Expression of beta-amyloid precursor protein in reactive astrocytes following neuronal damage. Neuron 1989;3:275-85; PMID:2518369; http://dx.doi.org/10.1016/0896-6273 (89) 90252-3
37. Skaper SD, Evans NA, Evans NA, Rosin C, Facci L, Richardson JC. Oligodendrocytes are a novel source of amyloid peptide generation. Neurochem Res 2009;34:2243-50; PMID:19557514; http://dx.doi.org/10.1007/s11064-009-0022-9
38. De Strooper B, Annaert W. Proteolytic processing and cell biological functions of the amyloid precursor protein. J Cell Sci 2000;113:1857-70; PMID:10806097
39. Desai MK, Mastrangelo MA, Ryan DA, Sudol KL, Narrow WC, Bowers WJ. Early oligodendrocyte/myelin pathology in Alzheimer's disease mice constitutes a novel therapeutic target. Am J Pathol 2010;177:1422-35; PMID:20696774; http://dx.doi.org/10.2353/ajpath.2010.100087
40. Connor JR. Myelin breakdown in Alzheimer's disease: a commentary. Neurobiol Aging 2004;25:45-7; PMID:14675730; http://dx.doi.org/10.1016/j. neurobiolaging.2003.06.004
41. Rasband MN, Kagawa T, Park EW, Ikenaka K, Trimmer JS. Dysregulation of axonal sodium channel isoforms after adult-onset chronic demyelination. J Neurosci Res 2003;73:465-70; PMID:12898531; http://dx.doi.org/10.1002/jnr.10675
42. Susuki K. Node of Ranvier disruption as a cause of neurological diseases. ASN Neuro 2013;5:209-19; PMID:23834220; http://dx.doi.org/10.1042/AN20130025
43. Nie DY, Zhou ZH, Ang BT, Teng FY, Xu G, Xiang T, Wang CY, Zeng L, Takeda Y, Xu TL, et al. Nogo-A at CNS paranodes is a ligand of Caspr: possible regulation of K (C) channel localization. EMBO J 2003;22:5666-78; PMID:14592966; http://dx.doi.org/10.1093/emboj/cdg570
44. Xiao ZC, Revest JM, Laeng P, Rougon G, Schachner M, Montag D. Defasciculation of neurites is mediated by tenascin-R and its neuronal receptor F3/11. J Neurosci Res 1998;52:390-404; PMID:9589384; http://dx.doi.org/10.1002/(SICI) 1097-4547 (19980515) 52:4-390::AID-JNR3-3.0. CO;2-4
45. Zheng H, Jiang M, Trumbauer ME, Sirinathsinghji DJ, Hopkins R, Smith DW, Heavens RP, Dawson GR, Boyce S, Conner MW, et al.. beta-Amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity. Cell 1995;81:525-31; PMID:7758106; http://dx.doi.org/10.1016/0092-8674 (95) 90073-X
46. Melendez-Vasquez CV, Rios JC, Zanazzi G, Lambert S, Bretscher A, Salzer JL. Nodes of Ranvier form in association with ezrin-radixin-moesin (ERM)-positive Schwann cell processes. Proc Natl Acad Sci U S A 2001;98:1235-40; PMID:11158623; http://dx.doi.org/10.1073/pnas.98.3.1235