Signals from the surface modulate differentiation of human pluripotent stem cells through glycosaminoglycans and integrins

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 51, 2014, Pages 18126-18131

  Wrighton, Paul J ^a   Klim, Joseph R ^a,c   Hernandez, Brandon A ^a   Koonce, Chad H ^b   Kamp, Timothy J ^b   Kiessling, Laura L ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^c Harvard University   (United States)

Author keywords

Biomaterials; Cell signaling; Human embryonic stem cells; Integrin linked kinase; Proteoglycan

Indexed keywords

ACTIVIN A; CHEMOKINE RECEPTOR CXCR4; GLYCOSAMINOGLYCAN; HEPATOCYTE NUCLEAR FACTOR 3BETA; INTEGRIN; INTEGRIN LINKED KINASE; MATRIGEL; OCTAMER TRANSCRIPTION FACTOR 4; PEPTIDE; PHOSPHATIDYLINOSITOL 3 KINASE; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CER1; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR OTX1; TRANSCRIPTION FACTOR OTX2; TRANSCRIPTION FACTOR PAX6; TRANSCRIPTION FACTOR SOX17; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG; VITRONECTIN; INTEGRIN-LINKED KINASE; MEMBRANE PROTEIN; PROTEIN SERINE THREONINE KINASE;

ARTICLE; CELL ADHESION; CELL CULTURE; CELL DIFFERENTIATION; CELL FATE; CELL INTERACTION; CELL SURFACE; CONTROLLED STUDY; ECTODERM; ENDODERM; GENE EXPRESSION; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MESODERM; MOTONEURON; PLURIPOTENT STEM CELL; PROTEIN INTERACTION; AMINO ACID SEQUENCE; CHEMISTRY; CYTOLOGY; EXTRACELLULAR MATRIX; METABOLISM; MOLECULAR GENETICS;

AMINO ACID SEQUENCE; CELL ADHESION; CELL DIFFERENTIATION; EXTRACELLULAR MATRIX; GLYCOSAMINOGLYCANS; HUMANS; INTEGRINS; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; PLURIPOTENT STEM CELLS; PROTEIN-SERINE-THREONINE KINASES;

EID: 84919898036     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1409525111     Document Type: Article

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