Depletion of poly(A)-specific ribonuclease (PARN) inhibits proliferation of human gastric cancer cells by blocking cell cycle progression

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1853, Issue 2, 2015, Pages 522-534

  Zhang, Li Na ^a   Yan, Yong Bin ^a  

^a Peking University   (China)

Author keywords

Cell cycle arrest; MRNA stability; P21; P53; Poly(A) specific ribonuclease; Tumor heterogeneity

Indexed keywords

CYCLIN D1; MESSENGER RNA; POLYADENYLIC ACID SPECIFIC RIBONUCLEASE; PROTEIN P21; PROTEIN P27; PROTEIN P53; RIBONUCLEASE; UNCLASSIFIED DRUG; CYCLIN DEPENDENT KINASE INHIBITOR 1A; EXORIBONUCLEASE; POLY(A)-SPECIFIC RIBONUCLEASE; POLYADENYLIC ACID;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ARTICLE; CANCER INHIBITION; CELL ADHESION; CELL CYCLE G1 PHASE; CELL CYCLE PROGRESSION; CELL DEATH; CELL FUNCTION; CELL HETEROGENEITY; CELL INVASION; CELL MIGRATION; CELL MOTILITY; CELL PROLIFERATION; CELL VIABILITY; COLONY FORMATION; CONTROLLED STUDY; DNA DAMAGE; DOWN REGULATION; G1 PHASE CELL CYCLE CHECKPOINT; GASTRIC CANCER CELL LINE; GENE SILENCING; HUMAN; HUMAN TISSUE; PHASE TRANSITION; PROTEIN EXPRESSION; RNA STABILITY; STOMACH CANCER; STOMACH TUMOR; UPREGULATION; CELL CYCLE; CELL GRANULE; CELL MOTION; DEFICIENCY; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; PROTEIN STABILITY; TUMOR CELL LINE;

CELL CYCLE; CELL DEATH; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYTOPLASMIC GRANULES; DNA DAMAGE; EXORIBONUCLEASES; G1 PHASE CELL CYCLE CHECKPOINTS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; HUMANS; POLY A; PROTEIN STABILITY; RNA STABILITY; RNA, MESSENGER; STOMACH NEOPLASMS; UP-REGULATION;

EID: 84919884123     PISSN: 01674889     EISSN: 18792596     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2014.12.004     Document Type: Article

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