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Volumn 13, Issue 22, 2014, Pages 3499-3505

The mitochondria-targeted antioxidant skq1 restores α-b-crystallin expression and protects against amd-like retinopathy in oxys rats

Author keywords

Age related macular degeneration; Oxys rats; SkQ1; crystallin; B crystallin

Indexed keywords

ALPHA CRYSTALLIN; ALPHAB CRYSTALLIN; ANTIOXIDANT; PLASTOQUINONYL DECYLTRIPHENYLPHOSPHONIUM; UNCLASSIFIED DRUG; 10-(6'-PLASTOQUINONYL)DECYLTRIPHENYLPHOSPHONIUM; PLASTOQUINONE; PROTECTIVE AGENT;

EID: 84919883148     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/15384101.2014.958393     Document Type: Article
Times cited : (25)

References (40)
  • 1
    • 79959208615 scopus 로고    scopus 로고
    • Age-related macular degeneration (AMD): Alzheimer's disease in the eye
    • PMID:21297256
    • Kaarniranta K, Salminen A, Haapasalo A, Soininen H, Hiltunen M. Age-related macular degeneration (AMD): Alzheimer's disease in the eye? J Alzheimers Dis 2011; 24(4):615-31; PMID:21297256; http://dx. doi.org/10.3233/JAD-2011-101908
    • (2011) Alzheimers Dis , vol.24 , Issue.4 , pp. 615-631
    • Kaarniranta, K.1    Salminen, A.2    Haapasalo, A.3    Soininen, H.4    Hiltunen, M.5
  • 2
    • 84887620237 scopus 로고    scopus 로고
    • ER stress-induced cell death mechanisms
    • PMID:23850759
    • Sano R, Reed JC. ER stress-induced cell death mechanisms. Biochim Biophys Acta 2013; 1833 (12):3460-70; PMID:23850759; http://dx.doi.org/ 10.1016/j.bbamcr.2013.06.028
    • (2013) Biochim Biophys Acta , vol.1833 , Issue.12 , pp. 3460-3470
    • Sano, R.1    Reed, J.C.2
  • 3
    • 84872530990 scopus 로고    scopus 로고
    • Gene expression changes in response to aging compared to heat stress, oxidative stress and ionizing radiation in Drosophila melanogaster
    • PMID:23211361
    • Landis G, Shen J, Tower J. Gene expression changes in response to aging compared to heat stress, oxidative stress and ionizing radiation in Drosophila melanogaster. Aging (Albany NY) 2012; 4(11):768-89; PMID:23211361
    • (2012) Aging (Albany NY) , vol.4 , Issue.11 , pp. 768-789
    • Landis, G.1    Shen, J.2    Tower, J.3
  • 4
    • 79451469767 scopus 로고    scopus 로고
    • New focus on alpha-crystallins in retinal neurodegenerative diseases
    • PMID:21115004
    • Fort PE, Lampi KJ. New focus on alpha-crystallins in retinal neurodegenerative diseases. Exp Eye Res 2011; 92(2):98-103; PMID:21115004; http://dx.doi.org/ 10.1016/j.exer.2010.11.008
    • (2011) Exp Eye Res , vol.92 , Issue.2 , pp. 98-103
    • Fort, P.E.1    Lampi, K.J.2
  • 6
    • 34147145520 scopus 로고    scopus 로고
    • Alpha-crystallin distribution in retinal pigment epithelium and effect of gene knockouts on sensitivity to oxidative stress
    • Yaung J, Jin M, Barron E, Spee C, Wawrousek EF, Kannan R, Hinton DR. Alpha-crystallin distribution in retinal pigment epithelium and effect of gene knockouts on sensitivity to oxidative stress. Mol Vis 2007; 13:566e577
    • (2007) Mol Vis , vol.13 , pp. 566e577
    • Yaung, J.1    Jin, M.2    Barron, E.3    Spee, C.4    Wawrousek, E.F.5    Kannan, R.6    Hinton, D.R.7
  • 7
    • 84867401896 scopus 로고    scopus 로고
    • Novel roles for α-crystallins in retinal function and disease
    • PMID:22721717
    • Kannan R, Sreekumar PG, Hinton DR. Novel roles for α-crystallins in retinal function and disease. Prog Retin Eye Res 2012; 31(6):576-604; PMID:22721717; http://dx.doi.org/10.1016/j.preteyeres.2012.06.001
    • (2012) Prog Retin Eye Res , vol.31 , Issue.6 , pp. 576-604
    • Kannan, R.1    Sreekumar, P.G.2    Hinton, D.R.3
  • 8
    • 84865473926 scopus 로고    scopus 로고
    • Deficiency of aB crystallin augments ER stress-induced apoptosis by enhancing mitochondrial dysfunction
    • 53 PMID:22781655
    • Dou G, Sreekumar PG, Spee C, He S, Ryan SJ, Kannan R, Hinton DR. Deficiency of aB crystallin augments ER stress-induced apoptosis by enhancing mitochondrial dysfunction. Free Radic Biol Med 2012; 1;53(5):1111-22; PMID:22781655; http://dx.doi.org/ 10.1016/j.freeradbiomed.2012.06.042
    • (2012) Free Radic Biol Med , vol.1 , Issue.5 , pp. 1111-1122
    • Dou, G.1    Sreekumar, P.G.2    Spee, C.3    He, S.4    Ryan, S.J.5    Kannan, R.6    Hinton, D.R.7
  • 9
    • 58149494297 scopus 로고    scopus 로고
    • Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 4. Age-related eye disease. SkQ1 returns vision to blind animals
    • PMID:19120017
    • Neroev VV, Archipova MM, Bakeeva LE, Fursova AZh, Grigorian EN, Grishanova AY, Iomdina EN, Ivashchenko ZhN, Katargina LA, Khoroshilova-Maslova IP, et al. Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 4. Age-related eye disease. SkQ1 returns vision to blind animals. Biochem (Mosc) 2008; 73 (12):1317-28; PMID:19120017; http://dx.doi.org/ 10.1134/S0006297908120043
    • (2008) Biochem Mosc , vol.73 , Issue.12 , pp. 1317-1328
    • Neroev, V.V.1    Archipova, M.M.2    Bakeeva, L.E.3    Fursova, A.4    Grigorian, E.N.5    Grishanova, A.Y.6    Iomdina, E.N.7    Ivashchenko, Z.8    Katargina, L.A.9    Khoroshilova-Maslova, I.P.10
  • 10
    • 77950681585 scopus 로고    scopus 로고
    • Lipofuscin granule dynamics during development of age-related macular degeneration
    • PMID:20367599
    • Saprunova VB, Pilipenko DI, Alexeevsky AV, Fursova AZh, Kolosova NG, Bakeeva LE. Lipofuscin granule dynamics during development of age-related macular degeneration. Biochem (Mosc) 2010; 75(2):130-8; PMID:20367599; http://dx.doi.org/10.1134/ S0006297910020021
    • (2010) Biochem (Mosc) , vol.75 , Issue.2 , pp. 130-138
    • Saprunova, V.B.1    Pilipenko, D.I.2    Alexeevsky, A.V.3    Fursova, A.4    Kolosova, N.G.5    Bakeeva, L.E.6
  • 11
    • 84864546287 scopus 로고    scopus 로고
    • SkQ1 slows development of age-dependent destructive processes in retina and vascular layer of eyes of wistar and OXYS rats
    • PMID:22817465
    • Saprunova VB, Lelekova MA, Kolosova NG, Bakeeva LE. SkQ1 slows development of age-dependent destructive processes in retina and vascular layer of eyes of wistar and OXYS rats. Biochem (Mosc) 2012; 77 (6):648-58; PMID:22817465; http://dx.doi.org/ 10.1134/S0006297912060120
    • (2012) Biochem (Mosc) , vol.77 , Issue.6 , pp. 648-658
    • Saprunova, V.B.1    Lelekova, M.A.2    Kolosova, N.G.3    Bakeeva, L.E.4
  • 14
    • 84872549344 scopus 로고    scopus 로고
    • The mitochondria-targeted antioxidant SkQ1 but not N-acetylcysteine reverses aging-related biomarkers in rats
    • PMID:23104863
    • Kolosova NG, Stefanova NA, Muraleva NA, Skulachev VP. The mitochondria-targeted antioxidant SkQ1 but not N-acetylcysteine reverses aging-related biomarkers in rats. Aging (Albany NY) 2012; 4(10):686-94; PMID:23104863
    • (2012) Aging (Albany NY) , vol.4 , Issue.10 , pp. 686-694
    • Kolosova, N.G.1    Stefanova, N.A.2    Muraleva, N.A.3    Skulachev, V.P.4
  • 17
    • 74849133990 scopus 로고    scopus 로고
    • Mitochondria-targeted antioxidant SkQ1 inhibits agedependent involution of the thymus in normal and senescence-prone rats
    • PMID:20195490
    • Obukhova LA, Skulachev VP, Kolosova NG. Mitochondria-targeted antioxidant SkQ1 inhibits agedependent involution of the thymus in normal and senescence-prone rats. Aging (Albany NY) 2009; 1 (4):389-401; PMID:20195490
    • (2009) Aging (Albany NY) , vol.1 , Issue.4 , pp. 389-401
    • Obukhova, L.A.1    Skulachev, V.P.2    Kolosova, N.G.3
  • 18
    • 83755206852 scopus 로고    scopus 로고
    • SkQ1 treatment and food restriction-two ways to retard an aging program of organisms
    • PMID: 22170754
    • Skulachev VP. SkQ1 treatment and food restriction-two ways to retard an aging program of organisms. Aging (Albany NY) 2011; 3(11):1045-50; PMID: 22170754
    • (2011) Aging (Albany NY) , vol.3 , Issue.11 , pp. 1045-1050
    • Skulachev, V.P.1
  • 20
    • 64749099950 scopus 로고    scopus 로고
    • Clinical and morphological characteristics of chorioretinal degeneration in early aging OXYS Rats
    • PMID:19489319
    • Zhdankina AA, Fursova AZh, Logvinov SV, Kolosova NG. Clinical and Morphological Characteristics of Chorioretinal Degeneration in Early Aging OXYS Rats. Bull Exp Biol Med 2008; 146(4):455-8; PMID:19489319; http://dx.doi.org/10.1007/s10517-009-0298-4
    • (2008) Bull Exp Biol Med , vol.146 , Issue.4 , pp. 455-458
    • Zhdankina, A.A.1    Fursova, A.2    Logvinov, S.V.3    Kolosova, N.G.4
  • 21
    • 79959919415 scopus 로고    scopus 로고
    • Therapeutic action of the mitochondria-targeted antioxidant SkQ1 on retinopathy in OXYS rats linked with improvement of VEGF and PEDF gene expression
    • PMID:21750722
    • Markovets AM, Fursova AZ, Kolosova NG. Therapeutic action of the mitochondria-targeted antioxidant SkQ1 on retinopathy in OXYS rats linked with improvement of VEGF and PEDF gene expression. PLoS One 2011; 6:e21682; PMID:21750722; http:// dx.doi.org/10.1371/journal.pone.0021682
    • (2011) PLoS One , vol.6 , pp. e21682
    • Markovets, A.M.1    Fursova, A.Z.2    Kolosova, N.G.3
  • 22
    • 84890555684 scopus 로고    scopus 로고
    • Association of AMDlike retinopathy development with an Alzheimer's disease metabolic pathway in OXYS rats
    • PMID:23959258
    • Kozhevnikova OS, Korbolina EE, Stefanova NA, Muraleva NA, Orlov YL, Kolosova NG. Association of AMDlike retinopathy development with an Alzheimer's disease metabolic pathway in OXYS rats. Biogerontology 2013; 14(6):753-62; PMID:23959258; http://dx.doi. org/10.1007/s10522-013-9439-2
    • (2013) Biogerontology , vol.14 , Issue.6 , pp. 753-762
    • Kozhevnikova, O.S.1    Korbolina, E.E.2    Stefanova, N.A.3    Muraleva, N.A.4    Orlov, Y.L.5    Kolosova, N.G.6
  • 23
    • 84878551469 scopus 로고    scopus 로고
    • Rat retinal transcriptome: Effects of aging and AMD-like retinopathy
    • PMID:23656783
    • Kozhevnikova OS, Korbolina EE, Ershov NI, Kolosova NG. Rat retinal transcriptome: effects of aging and AMD-like retinopathy. Cell Cycle 2013; 12(11):1745-61; PMID:23656783; http://dx.doi.org/10.4161/ cc.24825
    • (2013) Cell Cycle , vol.12 , Issue.11 , pp. 1745-1761
    • Kozhevnikova, O.S.1    Korbolina, E.E.2    Ershov, N.I.3    Kolosova, N.G.4
  • 24
    • 84859482962 scopus 로고    scopus 로고
    • Quantitative trait loci on chromosome 1 for cataract and AMD-like retinopathy in senescence-accelerated OXYS rats
    • PMID:22300709
    • Korbolina EE, Kozhevnikova OS, Stefanova NA, Kolosova NG. Quantitative trait loci on chromosome 1 for cataract and AMD-like retinopathy in senescence-accelerated OXYS rats. Aging (Albany NY) 2012; 4(1):49-59; PMID:22300709
    • (2012) Aging (Albany NY) , vol.4 , Issue.1 , pp. 49-59
    • Korbolina, E.E.1    Kozhevnikova, O.S.2    Stefanova, N.A.3    Kolosova, N.G.4
  • 25
    • 34248553886 scopus 로고    scopus 로고
    • Human retinal pigment epithelium cell changes and expression of alphaB-crystallin: A biomarker for retinal pigment epithelium cell change in age-related macular degeneration
    • PMID:17502503
    • De S, Rabin DM, Salero E, Lederman PL, Temple S, Stern JH. Human retinal pigment epithelium cell changes and expression of alphaB-crystallin: a biomarker for retinal pigment epithelium cell change in age-related macular degeneration. Arch Ophthalmol 2007; 125(5):641-5; PMID:17502503; http://dx.doi. org/10.1001/archopht.125.5.641
    • (2007) Arch Ophthalmol , vol.125 , Issue.5 , pp. 641-645
    • De, S.1    Rabin, D.M.2    Salero, E.3    Lederman, P.L.4    Temple, S.5    Stern, J.H.6
  • 26
    • 77951448229 scopus 로고    scopus 로고
    • AlphaB-crystallin regulation of angiogenesis by modulation of VEGF
    • 115 PMID:20023214
    • Kase S, He S, Sonoda S, Kitamura M, Spee C, Wawrousek E, Ryan SJ, Kannan R, Hinton DR. AlphaB-crystallin regulation of angiogenesis by modulation of VEGF. Blood 2010; 22;115(16):3398-406; PMID:20023214; http://dx.doi.org/10.1182/blood-2009-01-197095
    • (2010) Blood , vol.22 , Issue.16 , pp. 3398-3406
    • Kase, S.1    He, S.2    Sonoda, S.3    Kitamura, M.4    Spee, C.5    Wawrousek, E.6    Ryan, S.J.7    Kannan, R.8    Hinton, D.R.9
  • 27
    • 0033795036 scopus 로고    scopus 로고
    • The role of oxidative stress in the pathogenesis of age-related macular degeneration
    • PMID:11033038
    • Beatty S, Koh H, Henson D, Boulton M. The role of oxidative stress in the pathogenesis of age-related macular degeneration. Surv Ophthalmol 2000; 45(2):115-34; PMID:11033038; http://dx.doi.org/10.1016/ S0039-6257(00)00140-5
    • (2000) Urv Ophthalmol , vol.45 , Issue.2 , pp. 115-134
    • Beatty, S.1    Koh, H.2    Henson, D.3    Boulton, M.4
  • 28
    • 39149145829 scopus 로고    scopus 로고
    • Exacerbation of retinal degeneration in the absence of alpha crystallins in an in vivo model of chemically induced hypoxia
    • Yaung J, Kannan R, Wawrousek EF, Spee C, Sreekumar PG, Hinton DR. Exacerbation of retinal degeneration in the absence of alpha crystallins in an in vivo model of chemically induced hypoxia. Exp Eye Res 2008; 86:355e365; http://dx.doi.org/10.1016/j. exer.2007.11.007
    • (2008) Exp Eye Res , vol.86 , pp. 355e365
    • Yaung, J.1    Kannan, R.2    Wawrousek, E.F.3    Spee, C.4    Sreekumar, P.G.5    Hinton, D.R.6
  • 29
    • 42049088943 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress induced by oxidative stress in retinal pigment epithelial cells
    • PMID:18278507
    • He S, Yaung J, Kim YH, Barron E, Ryan SJ, Hinton DR. Endoplasmic reticulum stress induced by oxidative stress in retinal pigment epithelial cells. Graefes Arch Clin Exp Ophthalmol 2008; 246(5):677-83; PMID:18278507; http://dx.doi.org/10.1007/s00417-008-0770-2
    • (2008) Graefes Arch Clin Exp Ophthalmol , vol.246 , Issue.5 , pp. 677-683
    • He, S.1    Yaung, J.2    Kim, Y.H.3    Barron, E.4    Ryan, S.J.5    Hinton, D.R.6
  • 30
    • 84874985490 scopus 로고    scopus 로고
    • Chronic oxidative stress upregulates Drusenrelated protein expression in adult human RPE stem cell-derived RPE cells: A novel culture model for dry AMD
    • PMID:23257616
    • Rabin DM, Rabin RL, Blenkinsop TA, Temple S, Stern JH. Chronic oxidative stress upregulates Drusenrelated protein expression in adult human RPE stem cell-derived RPE cells: a novel culture model for dry AMD. Aging (Albany NY) 2013; 5(1):51-66; PMID:23257616
    • (2013) Aging (Albany NY) , vol.5 , Issue.1 , pp. 51-66
    • Rabin, D.M.1    Rabin, R.L.2    Blenkinsop, T.A.3    Temple, S.4    Stern, J.H.5
  • 31
    • 84874813390 scopus 로고    scopus 로고
    • Heat shock response and ionstasis: Axis against neurodegeneration
    • PMID:23257629
    • Kourtis N, Nikoletopoulou V, Tavernarakis N. Heat shock response and ionstasis: axis against neurodegeneration. Aging (Albany NY) 2012; 4(12):856-8; PMID:23257629
    • (2012) Aging (Albany NY) , vol.4 , Issue.12 , pp. 856-858
    • Kourtis, N.1    Nikoletopoulou, V.2    Tavernarakis, N.3
  • 32
    • 84887576517 scopus 로고    scopus 로고
    • Ecretion of aB-Crystallin via exosomes: New clues to the function of human retinal pigment epithelium
    • PMID:22446542
    • Bhat SP, Gangalum RK. Secretion of aB-Crystallin via exosomes: new clues to the function of human retinal pigment epithelium. Commun Integr Biol 2011; 1;4 (6):739-41; PMID:22446542; http://dx.doi.org/ 10.4161/cib.17610
    • (2011) Commun Integr Biol , vol.1-4 , Issue.6 , pp. 739-741
    • Bhat, S.P.1    Gangalum, R.K.2
  • 33
    • 30344447284 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor (PEDF) and vascular endothelial growth factor (VEGF) in aged human choroid and eyes with agerelated macular degeneration
    • PMID:16019000
    • Bhutto IA, McLeod DS, Hasegawa T, Kim SY, Merges C, Tong P, Lutty GA. Pigment epithelium-derived factor (PEDF) and vascular endothelial growth factor (VEGF) in aged human choroid and eyes with agerelated macular degeneration. Exp Eye Res 2006; 82 (1):99-110; PMID:16019000; http://dx.doi.org/ 10.1016/j.exer.2005.05.007
    • (2006) Exp Eye Res , vol.82 , Issue.1 , pp. 99-110
    • Bhutto, I.A.1    McLeod, D.S.2    Hasegawa, T.3    Kim, S.Y.4    Merges, C.5    Tong, P.6    Lutty, G.A.7
  • 34
    • 84876316567 scopus 로고    scopus 로고
    • Effect of vascular endothelial growth factor upregulation on retinal gene expression in the Kimba mouse
    • PMID:22788671
    • Binz N, Ali Rahman IS, Chinnery HR, McKeone R, Simpson KM, Speed TP, Lai CM, Rakoczy PE. Effect of vascular endothelial growth factor upregulation on retinal gene expression in the Kimba mouse. Clin Experiment Ophthalmol 2013; 41(3):251-62; PMID:22788671; http://dx.doi.org/10.1111/j.1442-9071.2012.02845.x
    • (2013) Clin Experiment Ophthalmol , vol.41 , Issue.3 , pp. 251-262
    • Binz, N.1    Ali Rahman, I.S.2    Chinnery, H.R.3    McKeone, R.4    Simpson, K.M.5    Speed, T.P.6    Lai, C.M.7    Rakoczy, P.E.8
  • 35
    • 81255151066 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in retinal diseases
    • PMID:21978133
    • Barot M, Gokulgandhi MR, Mitra AK. Mitochondrial dysfunction in retinal diseases. Curr Eye Res 2011; 36 (12):1069-77; PMID:21978133; http://dx.doi.org/ 10.3109/02713683.2011.607536
    • (2011) Curr Eye Res , vol.36 , Issue.12 , pp. 1069-1077
    • Barot, M.1    Gokulgandhi, M.R.2    Mitra, A.K.3
  • 36
    • 0035712726 scopus 로고    scopus 로고
    • Dynamics of structural and functional changes in hepatocyte mitochondria of senescence-accelerated OXYS rats
    • PMID:11713575
    • Kolosova NG, Aidagulova SV, Nepomnyashchikh GI, Shabalina IG, Shalbueva NI. Dynamics of structural and functional changes in hepatocyte mitochondria of senescence-accelerated OXYS rats. Bull Exp Biol Med 2001; 132(2):814-9; PMID:11713575; http://dx.doi. org/10.1023/A:1013014919721
    • (2001) Bull Exp Biol Med , vol.132 , Issue.2 , pp. 814-819
    • Kolosova, N.G.1    Aidagulova, S.V.2    Nepomnyashchikh, G.I.3    Shabalina, I.G.4    Shalbueva, N.I.5
  • 37
    • 84886891597 scopus 로고    scopus 로고
    • Potential of melatonin for prevention of agerelated macular degeneration: Experimental study
    • PMID:24003738
    • Stefanova NA, Zhdankina AA, Fursova AZh, Kolosova NG. Potential of melatonin for prevention of agerelated macular degeneration: experimental study. Adv Gerontol 2013; 26(1):122-9; PMID:24003738
    • (2013) Adv Gerontol , vol.26 , Issue.1 , pp. 122-129
    • Stefanova, N.A.1    Zhdankina, A.A.2    Fursova, A.3    Kolosova, N.G.4
  • 38
    • 33745998064 scopus 로고    scopus 로고
    • Long-term antioxidant supplementation attenuates oxidative stress markers and cognitive deficits in senes-cent-accelerated OXYS rats
    • PMID:16246464
    • Kolosova NG, Shcheglova TV, Sergeeva SV, Loskutova LV. Long-term antioxidant supplementation attenuates oxidative stress markers and cognitive deficits in senes-cent-accelerated OXYS rats. Neurobiol Aging 2006; 27 (9):1289-97; PMID:16246464; http://dx.doi.org/ 10.1016/j.neurobiolaging.2005.07.022
    • (2006) Neurobiol Aging , vol.27 , Issue.9 , pp. 1289-1297
    • Kolosova, N.G.1    Shcheglova, T.V.2    Sergeeva, S.V.3    Loskutova, L.V.4
  • 39
    • 78149466716 scopus 로고    scopus 로고
    • ABCrystallin inhibits the cell toxicity associated with amyloid fibril formation by k-casein and the amyloidb peptide
    • Dehle FC, Ecroyd H, Musgrave IF, Carver JA. aBCrystallin inhibits the cell toxicity associated with amyloid fibril formation by k-casein and the amyloidb peptide. Cell Stress Chaperones 2010; 15:1013e1026; http://dx.doi.org/10.1007/s12192-010-0212-z
    • (2010) Cell Stress Chaperones , vol.15 , pp. 1013e1026
    • Dehle, F.C.1    Ecroyd, H.2    Musgrave, I.F.3    Carver, J.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.