Propofol inhibits proliferation and induces neuroapoptosis of hippocampal neurons in vitro via downregulation of NF-κB p65 and Bcl-2 and upregulation of caspase-3

Cell Biochemistry and Function

Volumn 32, Issue 8, 2014, Pages 720-729

  Zhong, Yuling ^a   Liang, Yubing ^a   Chen, Jing ^a   Li, Li ^a   Qin, Yi ^a   Guan, Enjian ^a   He, Dan ^a   Wei, Yi ^a   Xie, Yubo ^a   Xiao, Qiang ^a  

^a FIRST AFFILIATED HOSPITAL OF GUANGXI MEDICAL UNIVERSITY   (China)

Author keywords

Bcl 2; Caspase 3; Neuroapoptosis; Neurotoxicity; NF B; Proliferation; Propofol

Indexed keywords

CASPASE 3; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTRALIPID; MESSENGER RNA; PROPOFOL; PROTEIN BCL 2; INTRAVENOUS ANESTHETIC AGENT; TRANSCRIPTION FACTOR RELA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; EMBRYO; ENZYME ACTIVATION; GESTATIONAL AGE; HIPPOCAMPUS; IN VITRO STUDY; NERVE CELL; NERVE CELL GROWTH; NERVE CELL INHIBITION; NEUROAPOPTOSIS; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; METABOLISM; SPRAGUE DAWLEY RAT;

ANESTHETICS, INTRAVENOUS; ANIMALS; APOPTOSIS; CASPASE 3; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; DOWN-REGULATION; HIPPOCAMPUS; NEURONS; PROPOFOL; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR RELA; UP-REGULATION;

EID: 84919840816     PISSN: 02636484     EISSN: 10990844     Source Type: Journal    
DOI: 10.1002/cbf.3077     Document Type: Article

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