Mitochondrial remodeling in mice with cardiomyocyte-specific lipid overload

Journal of Molecular and Cellular Cardiology

Volumn 79, Issue , 2015, Pages 275-283

  Elezaby, Aly ^a   Sverdlov, Aaron L ^a   Tu, Vivian H ^a   Soni, Kanupriya ^a   Luptak, Ivan ^a   Qin, Fuzhong ^a   Liesa, Marc ^b   Shirihai, Orian S ^b   Rimer, Jamie ^c   Schaffer, Jean E ^c   Wilson S , Colucci ^a   Edward J , Miller ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BOSTON UNIVERSITY   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Lipid excess; Metabolic heart disease; Mitochondria; Obesity

Indexed keywords

ACYLCARNITINE; CATALASE; CERAMIDE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DIACYLGLYCEROL; FATTY ACID TRANSPORTER; FATTY ACID TRANSPORTER 1; HYDROGEN PEROXIDE; MITOFUSIN 1; MITOFUSIN 2; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROTEIN KINASE B; PROTEIN KINASE C ALPHA; PROTEIN KINASE C DELTA; REACTIVE OXYGEN METABOLITE; SPHINGOMYELIN; SUCCINATE DEHYDROGENASE (UBIQUINONE); UNCLASSIFIED DRUG; ADENOSINE TRIPHOSPHATE; CARNITINE; LIPID; MESSENGER RNA; PPARGC1A PROTEIN, MOUSE; PROTEIN KINASE C; SLC27A1 PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELLULAR, SUBCELLULAR AND MOLECULAR BIOLOGICAL PHENOMENA AND FUNCTIONS; CONTROLLED STUDY; DIASTOLIC DYSFUNCTION; DOWN REGULATION; ENERGETIC FUNCTION; ENZYME PHOSPHORYLATION; FUSION GENE; GENE EXPRESSION REGULATION; HEART DISEASE; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; LIPID STORAGE; METABOLIC DISORDER; METABOLIC HEART DISEASE; METABOLITE; MFN1 GENE; MFN2 GENE; MITOCHONDRIAL GENE; MITOCHONDRIAL REMODELING; MITOCHONDRIAL RESPIRATION; MITOCHONDRIAL STRUCTURE; MITOCHONDRIAL VOLUME; MOUSE; NONHUMAN; OPA1 GENE; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN SUBUNIT; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; ANALOGS AND DERIVATIVES; ANIMAL; ANTIBODY SPECIFICITY; BIOLOGICAL MODEL; CARDIAC MUSCLE; CARDIAC MUSCLE CELL; GENETICS; HEART MITOCHONDRION; METABOLISM; OXYGEN CONSUMPTION; PATHOLOGY; PHOSPHORYLATION; ULTRASTRUCTURE;

MUS;

ADENOSINE TRIPHOSPHATE; ANIMALS; CARNITINE; CATALASE; CERAMIDES; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DIGLYCERIDES; ELECTRON TRANSPORT COMPLEX II; FATTY ACID TRANSPORT PROTEINS; GENE EXPRESSION REGULATION; HYDROGEN PEROXIDE; LIPIDS; MICE; MITOCHONDRIA, HEART; MODELS, BIOLOGICAL; MYOCARDIUM; MYOCYTES, CARDIAC; ORGAN SPECIFICITY; OXYGEN CONSUMPTION; PHOSPHORYLATION; PPAR ALPHA; PROTEIN KINASE C; PROTO-ONCOGENE PROTEINS C-AKT; RNA, MESSENGER; SPHINGOMYELINS; TRANSCRIPTION FACTORS;

EID: 84919800659     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2014.12.001     Document Type: Article

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