Mitochondrial dysfunction in the type 2 diabetic heart is associated with alterations in spatially distinct mitochondrial proteomes

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 299, Issue 2, 2010, Pages

  Dabkowski, Erinne R ^a,b,d   Baseler, Walter A ^a,b,d   Williamson, Courtney L ^a,b,d   Powell, Matthew ^e   Razunguzwa, Trust T ^e   Frisbee, Jefferson C ^a,c,d   Hollander, John M ^a,b,d  

^a WEST VIRGINIA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Division of Exercise Physiology   (United States)

^c Department of Physiology ^*  (United States)

^d Center for Cardiovascular and Respiratory Sciences   (United States)

^e Protea Biosciences   (United States)

Author keywords

Diabetes; Mitochondria; Proteomics

Indexed keywords

ADENOSINE TRIPHOSPHATE; PROTEOME; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DIABETIC CARDIOMYOPATHY; ENZYME ACTIVITY; HEART MITOCHONDRION; LIPID PEROXIDATION; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RESPIRATORY CHAIN;

ANIMALS; ANTIOXIDANTS; CELL RESPIRATION; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; ELECTRON TRANSPORT; ELECTRON TRANSPORT CHAIN COMPLEX PROTEINS; ION CHANNELS; LIPID PEROXIDATION; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MITOCHONDRIA, HEART; MITOCHONDRIAL ADP, ATP TRANSLOCASES; MITOCHONDRIAL PROTEINS; MITOCHONDRIAL PROTON-TRANSLOCATING ATPASES; MITOCHONDRIAL SIZE; OXIDATIVE STRESS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEOME; PROTEOMICS; TYROSINE;

EID: 77955435653     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00267.2010     Document Type: Article

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