High fat, high sucrose diet causes cardiac mitochondrial dysfunction due in part to oxidative post-translational modification of mitochondrial complex II

Journal of Molecular and Cellular Cardiology

Volumn 78, Issue , 2015, Pages 165-173

  Sverdlov, Aaron L ^a   Elezaby, Aly ^a   Behring, Jessica B ^a   Bachschmid, Markus M ^a   Luptak, Ivan ^a   Tu, Vivian H ^a   Siwik, Deborah A ^a   Miller, Edward J ^a   Liesa, Marc ^a   Shirihai, Orian S ^a   Pimentel, David R ^a   Cohen, Richard A ^a   Colucci, Wilson S ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Metabolic heart disease; Mitochondria; Obesity; Oxidative protein modifications; Oxidative stress

Indexed keywords

ADENOSINE TRIPHOSPHATE; GLUTATHIONE; GLUTATHIONE DISULFIDE; HYDROGEN PEROXIDE; MITOCHONDRIAL COMPLEX II; MITOCHONDRIAL PROTEIN; UNCLASSIFIED DRUG; REACTIVE OXYGEN METABOLITE; SUCCINATE DEHYDROGENASE (UBIQUINONE);

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIAC MITOCHONDRIAL DYSFUNCTION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVITY; ENZYME METABOLISM; ENZYME SUBSTRATE; HEART DISEASE; HEART MITOCHONDRION; LIPID DIET; MALE; MITOCHONDRIAL ENERGY TRANSFER; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROCESSING; SUGAR INTAKE; ADVERSE EFFECTS; ANIMAL; ENZYME ACTIVATION; METABOLISM; OXIDATION REDUCTION REACTION;

MUS;

ADENOSINE TRIPHOSPHATE; ANIMALS; DIET, HIGH-FAT; ELECTRON TRANSPORT COMPLEX II; ENZYME ACTIVATION; GLUTATHIONE; HYDROGEN PEROXIDE; MALE; MICE; MITOCHONDRIA, HEART; MITOCHONDRIAL PROTEINS; OXIDATION-REDUCTION; OXIDATIVE STRESS; PROTEIN PROCESSING, POST-TRANSLATIONAL; REACTIVE OXYGEN SPECIES;

EID: 84916595679     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2014.07.018     Document Type: Article

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