Effects of bleomycin, etoposide and cisplatin treatment on Leydig cell structure and transcription of steroidogenic enzymes in rat testis

European Journal of Pharmacology

Volumn 747, Issue , 2015, Pages 150-159

  Al Bader, Maie ^a   Kilarkaje, Narayana ^a  

^a KUWAIT UNIVERSITY   (Kuwait)

Author keywords

Anticancer drugs; Hypogonadism; Leydig cells; Pituitary testicular hormonal axis; Testosterone synthesis

Indexed keywords

AROMATASE; BLEOMYCIN; CHOLESTEROL; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); CISPLATIN; ETOPOSIDE; LUTEINIZING HORMONE RECEPTOR; SCAVENGER RECEPTOR BI; STEROIDOGENIC ACUTE REGULATORY PROTEIN; TESTOSTERONE; TESTOSTERONE 17BETA DEHYDROGENASE; LUTEINIZING HORMONE;

ADULT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DEGENERATION; CELL HYPERPLASIA; CELL POPULATION; CELL PROLIFERATION; CELL STRUCTURE; CONTROLLED STUDY; CYP11A1 GENE; CYP17A1 GENE; CYP19A1 GENE; DRUG EFFECT; GENE; GENE EXPRESSION; GENETIC TRANSCRIPTION; HSD17B6 GENE; HSD3B1 GENE; LEYDIG CELL; LHRCG GENE; LUTEINIZING HORMONE RECEPTOR GENE; MALE; MULTIPLE CYCLE TREATMENT; NONHUMAN; OXIDATIVE STRESS; RAT; SCARB1 GENE; STAR GENE; TREATMENT DURATION; ANIMAL; BIOSYNTHESIS; DOSE RESPONSE; DRUG EFFECTS; GENE EXPRESSION REGULATION; METABOLISM; SPRAGUE DAWLEY RAT; TIME;

ANIMALS; BLEOMYCIN; CHOLESTEROL; CISPLATIN; DOSE-RESPONSE RELATIONSHIP, DRUG; ETOPOSIDE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; LEYDIG CELLS; LUTEINIZING HORMONE; MALE; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; TESTOSTERONE; TIME FACTORS; TRANSCRIPTION, GENETIC;

EID: 84919800529     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2014.12.006     Document Type: Article

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