The effects of chemotherapy with bleomycin, etoposide, and cis-platinum (BEP) on rat sperm chromatin remodeling, fecundity and testicular gene expression in the progeny

Biology of Reproduction

Volumn 89, Issue 4, 2013, Pages

  Maselli, Jennifer ^a   Hales, Barbara F ^a   Robaire, Bernard ^a,b  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

Author keywords

Chemotherapeutics; Chromatin; Histones; Male fertility; Spermatozoa

Indexed keywords

BLEOMYCIN; CISPLATIN; ETOPOSIDE; HISTONE H2AX; HISTONE H4; PROTAMINE; PROTAMINE P1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CHEMOTHERAPY; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMATIN STRUCTURE; CONTROLLED STUDY; EPIDIDYMIS TAIL; EPIGENETICS; FEMALE; GENE EXPRESSION; INHERITANCE; LITTER SIZE; MALE; MALE INFERTILITY; MATING; NONHUMAN; NUCLEOTIDE SEQUENCE; PERINATAL PERIOD; PRIORITY JOURNAL; PROGENY; PROTEIN EXPRESSION; PROTEIN PROCESSING; RAT; SPERM; SPERMATID; SPERMATOGENESIS; SPERMATOZOON; TESTIS CANCER; TESTIS DEVELOPMENT; TRANSLATION REGULATION; UPREGULATION; WESTERN BLOTTING;

CHEMOTHERAPEUTICS; CHROMATIN; F1 TRANSMISSION; HISTONES; MALE FERTILITY; SPERMATOZOA;

ANIMALS; ANIMALS, NEWBORN; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BLEOMYCIN; CHROMATIN ASSEMBLY AND DISASSEMBLY; CISPLATIN; CROSSES, GENETIC; EPIDIDYMIS; EPIGENESIS, GENETIC; ETOPOSIDE; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HISTONES; LITTER SIZE; MALE; PATERNAL EXPOSURE; PREGNANCY; RATS; RATS, INBRED BN; RATS, SPRAGUE-DAWLEY; SPERMATOGENESIS; TESTIS;

EID: 84894337735     PISSN: 00063363     EISSN: 15297268     Source Type: Journal    
DOI: 10.1095/biolreprod.113.110759     Document Type: Article

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