Diabetes-induced DNA damage and apoptosis are associated with poly (ADP ribose) polymerase 1 inhibition in the rat testis

European Journal of Pharmacology

Volumn 737, Issue , 2014, Pages 29-40

  Kilarkaje, Narayana ^a   Al Hussaini, Heba ^a   Al Bader, Maie M ^a  

^a KUWAIT UNIVERSITY   (Kuwait)

Author keywords

DNA damage; DNA repair; Germ cell apoptosis; Hyperglycemia; Hypogonadism; Infertility

Indexed keywords

NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; 8-OXO-7-HYDRODEOXYGUANOSINE; DEOXYGUANOSINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE ASSOCIATION; DNA DAMAGE; DNA MODIFICATION; DNA STRAND BREAKAGE; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; GENE OVEREXPRESSION; GERM CELL; HYPERGLYCEMIA; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; RAT; SERTOLI CELL; SPERMATOZOON COUNT; SPERMATOZOON MOTILITY; TESTIS DISEASE; TESTIS WEIGHT; UPREGULATION; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; ENZYMOLOGY; EXPERIMENTAL DIABETES MELLITUS; GENE EXPRESSION REGULATION; GENETICS; MALE; METABOLISM; ORGAN SIZE; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; REPRODUCTION; SEMINIFEROUS TUBULE EPITHELIUM; SPERMATOZOON; SPRAGUE DAWLEY RAT; TESTIS;

ANIMALS; APOPTOSIS; DEOXYGUANOSINE; DIABETES MELLITUS, EXPERIMENTAL; DNA DAMAGE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; MALE; ORGAN SIZE; OXIDATIVE STRESS; POLY(ADP-RIBOSE) POLYMERASES; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCTION; SEMINIFEROUS EPITHELIUM; SERTOLI CELLS; SPERM COUNT; SPERM MOTILITY; SPERMATOZOA; TESTIS;

EID: 84901383527     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2014.05.005     Document Type: Article

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