메뉴 건너뛰기




Volumn 6, Issue 12, 2014, Pages 1279-1293

Past, present and future targets for immunotherapy in ovarian cancer

Author keywords

adoptive transfer; CA125; EpCAM; mesothelin; NY ESO 1; ovarian cancer; p53; tumor associated antigens; tumor vaccines; WT 1

Indexed keywords

ABAGOVOMAB; AMATUXIMAB; BAY 94 9343; BEVACIZUMAB; BMS 936559; CA 125 ANTIGEN; CARBOPLATIN; CATUMAXOMAB; CD3 ANTIBODY; CRS 207; CYCLOPHOSPHAMIDE; DRUG ANTIBODY; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPITHELIAL CELL ADHESION MOLECULE; FLUDARABINE; IPILIMUMAB; MESOTHELIN; NIVOLUMAB; NY ESO 1 ANTIGEN; OREGOVOMAB; PACLITAXEL; PLACEBO; PROTEIN P53; PSEUDOMONAS EXOTOXIN; TUMOR CELL VACCINE; TUMOR VACCINE; UNCLASSIFIED DRUG; UNINDEXED DRUG; V SET DOMAIN CONTAINING T CELL ACTIVATION INHIBITOR 1; VASCULOTROPIN RECEPTOR; WT1 PROTEIN;

EID: 84919785847     PISSN: 1750743X     EISSN: 17507448     Source Type: Journal    
DOI: 10.2217/imt.14.90     Document Type: Review
Times cited : (40)

References (135)
  • 2
    • 0037448353 scopus 로고    scopus 로고
    • Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer
    • Zhang L, Conejo-Garcia JR, Katsaros D et al. Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer. N. Engl. J. Med. 348(3), 203-213 (2003).
    • (2003) N. Engl. J. Med. , vol.348 , Issue.3 , pp. 203-213
    • Zhang, L.1    Conejo-Garcia, J.R.2    Katsaros, D.3
  • 3
    • 79953151458 scopus 로고    scopus 로고
    • Cancer immunoediting: Integrating immunity's roles in cancer suppression and promotion
    • Schreiber RD, Old LJ, Smyth MJ. Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion. Science 331(6024), 1565-1570 (2011).
    • (2011) Science , vol.331 , Issue.6024 , pp. 1565-1570
    • Schreiber, R.D.1    Old, L.J.2    Smyth, M.J.3
  • 4
    • 80052832382 scopus 로고    scopus 로고
    • Human ovarian tumor cells escape gammadelta Tcell recognition partly by down regulating surface expression of MICA and limiting cell cycle related molecules
    • Lu J, Aggarwal R, Kanji S et al. Human ovarian tumor cells escape gammadelta Tcell recognition partly by down regulating surface expression of MICA and limiting cell cycle related molecules. PLoS ONE 6(9), e23348 (2011).
    • (2011) PLoS ONE , vol.6 , Issue.9 , pp. e23348
    • Lu, J.1    Aggarwal, R.2    Kanji, S.3
  • 5
    • 33846794698 scopus 로고    scopus 로고
    • Self/non-self discrimination by human gamma delta Tcells: Simple solutions for a complex issue?
    • Thedrez A, Sabourin C, Gertner J et al. Self/non-self discrimination by human gamma delta Tcells: simple solutions for a complex issue? Immunol. Rev. 215, 123-135 (2007).
    • (2007) Immunol. Rev. , vol.215 , pp. 123-135
    • Thedrez, A.1    Sabourin, C.2    Gertner, J.3
  • 6
    • 33847611968 scopus 로고    scopus 로고
    • Programmed cell death 1 ligand 1 and tumor-infiltrating CD8+ T lymphocytes are prognostic factors of human ovarian cancer
    • Hamanishi J, Mandai M, Iwasaki M et al. Programmed cell death 1 ligand 1 and tumor-infiltrating CD8+ T lymphocytes are prognostic factors of human ovarian cancer. Proc. Natl Acad. Sci. USA 104(9), 3360-3365 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , Issue.9 , pp. 3360-3365
    • Hamanishi, J.1    Mandai, M.2    Iwasaki, M.3
  • 8
    • 47249093196 scopus 로고    scopus 로고
    • Macrophage migration inhibitory factor contributes to the immune escape of ovarian cancer by down-regulating NKG2D
    • Krockenberger M, Dombrowski Y, Weidler C et al. Macrophage migration inhibitory factor contributes to the immune escape of ovarian cancer by down-regulating NKG2D. J. Immunol. 180(11), 7338-7348 (2008).
    • (2008) J. Immunol. , vol.180 , Issue.11 , pp. 7338-7348
    • Krockenberger, M.1    Dombrowski, Y.2    Weidler, C.3
  • 9
    • 29444442811 scopus 로고    scopus 로고
    • +/regulatory Tcell ratio are associated with favorable prognosis in ovarian cancer
    • +/regulatory Tcell ratio are associated with favorable prognosis in ovarian cancer. Proc. Natl Acad. Sci. USA 102(51), 18538-18543 (2005).
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , Issue.51 , pp. 18538-18543
    • Sato, E.1    Olson, S.H.2    Ahn, J.3
  • 10
    • 4644237613 scopus 로고    scopus 로고
    • Specific recruitment of regulatory Tcells in ovarian carcinoma fosters immune privilege and predicts reduced survival
    • Curiel TJ, Coukos G, Zou L et al. Specific recruitment of regulatory Tcells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat. Med. 10(9), 942-949 (2004).
    • (2004) Nat. Med. , vol.10 , Issue.9 , pp. 942-949
    • Curiel, T.J.1    Coukos, G.2    Zou, L.3
  • 11
    • 22144446042 scopus 로고    scopus 로고
    • ICAM-1 regulates neutrophil adhesion and transcellular migration of TNF-alpha-activated vascular endothelium under flow
    • Yang L, Froio RM, Sciuto TE, Dvorak AM, Alon R, Luscinskas FW. ICAM-1 regulates neutrophil adhesion and transcellular migration of TNF-alpha-activated vascular endothelium under flow. Blood 106(2), 584-592 (2005).
    • (2005) Blood , vol.106 , Issue.2 , pp. 584-592
    • Yang, L.1    Froio, R.M.2    Sciuto, T.E.3    Dvorak, A.M.4    Alon, R.5    Luscinskas, F.W.6
  • 12
    • 84899130785 scopus 로고    scopus 로고
    • MUC16 mucin (CA125) attenuates TRAIL-induced apoptosis by decreasing TRAIL receptor R2 expression and increasing c-FLIP expression
    • Matte I, Lane D, Boivin M, Rancourt C, Piche A. MUC16 mucin (CA125) attenuates TRAIL-induced apoptosis by decreasing TRAIL receptor R2 expression and increasing c-FLIP expression. BMC Cancer 14(1), 234 (2014).
    • (2014) BMC Cancer , vol.14 , Issue.1 , pp. 234
    • Matte, I.1    Lane, D.2    Boivin, M.3    Rancourt, C.4    Piche, A.5
  • 13
    • 84862557227 scopus 로고    scopus 로고
    • + T cells promote favorable prognosis in ovarian cancer
    • + T cells promote favorable prognosis in ovarian cancer. Clin. Cancer Res. 18(12), 3281-3292 (2012).
    • (2012) Clin. Cancer Res. , vol.18 , Issue.12 , pp. 3281-3292
    • Nielsen, J.S.1    Sahota, R.A.2    Milne, K.3
  • 14
    • 79959838081 scopus 로고    scopus 로고
    • Integrated genomic analyses of ovarian carcinoma
    • Cancer Genome Atlas Research N. Integrated genomic analyses of ovarian carcinoma. Nature 474(7353), 609-615 (2011).
    • (2011) Nature , vol.474 , Issue.7353 , pp. 609-615
  • 15
    • 52649085237 scopus 로고    scopus 로고
    • Novel molecular subtypes of serous and endometrioid ovarian cancer linked to clinical outcome
    • Tothill RW, Tinker AV, George J et al. Novel molecular subtypes of serous and endometrioid ovarian cancer linked to clinical outcome. Clin. Cancer Res. 14(16), 5198-5208 (2008).
    • (2008) Clin. Cancer Res. , vol.14 , Issue.16 , pp. 5198-5208
    • Tothill, R.W.1    Tinker, A.V.2    George, J.3
  • 16
    • 0021845657 scopus 로고
    • Anti-tumor effect of inflammatory neutrophils: Characteristics of invivo generation and invitro tumor cell lysis
    • Lichtenstein A, Kahle J. Anti-tumor effect of inflammatory neutrophils: characteristics of invivo generation and invitro tumor cell lysis. Int. J. Cancer 35(1), 121-127 (1985).
    • (1985) Int. J. Cancer , vol.35 , Issue.1 , pp. 121-127
    • Lichtenstein, A.1    Kahle, J.2
  • 17
    • 0022459880 scopus 로고
    • Therapy of stage III (optimal) epithelial carcinoma of the ovary with melphalan or melphalan plus Corynebacterium parvum (a Gynecologic Oncology Group Study)
    • Gall S, Bundy B, Beecham J et al. Therapy of stage III (optimal) epithelial carcinoma of the ovary with melphalan or melphalan plus Corynebacterium parvum (a Gynecologic Oncology Group Study). Gynecol. Oncol. 25(1), 26-36 (1986).
    • (1986) Gynecol. Oncol. , vol.25 , Issue.1 , pp. 26-36
    • Gall, S.1    Bundy, B.2    Beecham, J.3
  • 19
    • 0026503664 scopus 로고
    • Isolation and characterization of a monoclonal antibody, K1, reactive with ovarian cancers and normal mesothelium
    • Chang K, Pastan I, Willingham MC. Isolation and characterization of a monoclonal antibody, K1, reactive with ovarian cancers and normal mesothelium. Int. J. Cancer 50(3), 373-381 (1992).
    • (1992) Int. J. Cancer , vol.50 , Issue.3 , pp. 373-381
    • Chang, K.1    Pastan, I.2    Willingham, M.C.3
  • 20
    • 84856519280 scopus 로고    scopus 로고
    • A live-attenuated Listeria vaccine (ANZ-100) and a live-attenuated Listeria vaccine expressing mesothelin (CRS-207) for advanced cancers: Phase I studies of safety and immune induction
    • Le DT, Brockstedt DG, Nir-Paz R et al. A live-attenuated Listeria vaccine (ANZ-100) and a live-attenuated Listeria vaccine expressing mesothelin (CRS-207) for advanced cancers: Phase I studies of safety and immune induction. Clin. Cancer Res. 18(3), 858-868 (2012).
    • (2012) Clin. Cancer Res. , vol.18 , Issue.3 , pp. 858-868
    • Le, D.T.1    Brockstedt, D.G.2    Nir-Paz, R.3
  • 21
    • 84859379903 scopus 로고    scopus 로고
    • Mesothelin-targeted agents in clinical trials and in preclinical development
    • Kelly RJ, Sharon E, Pastan I, Hassan R. Mesothelin-targeted agents in clinical trials and in preclinical development. Mol. Cancer. Ther. 11(3), 517-525 (2012).
    • (2012) Mol. Cancer. Ther. , vol.11 , Issue.3 , pp. 517-525
    • Kelly, R.J.1    Sharon, E.2    Pastan, I.3    Hassan, R.4
  • 22
    • 37249038187 scopus 로고    scopus 로고
    • Mesothelin targeted cancer immunotherapy
    • Hassan R, Ho M. Mesothelin targeted cancer immunotherapy. Eur. J. Cancer 44(1), 46-53 (2008).
    • (2008) Eur. J. Cancer , vol.44 , Issue.1 , pp. 46-53
    • Hassan, R.1    Ho, M.2
  • 23
    • 0141507936 scopus 로고    scopus 로고
    • NY-ESO-1 and LAGE-1 cancer-testis antigens are potential targets for immunotherapy in epithelial ovarian cancer
    • Odunsi K, Jungbluth AA, Stockert E et al. NY-ESO-1 and LAGE-1 cancer-testis antigens are potential targets for immunotherapy in epithelial ovarian cancer. Cancer Res. 63(18), 6076-6083 (2003).
    • (2003) Cancer Res. , vol.63 , Issue.18 , pp. 6076-6083
    • Odunsi, K.1    Jungbluth, A.A.2    Stockert, E.3
  • 24
    • 33749237126 scopus 로고    scopus 로고
    • Recombinant vaccinia/fowlpox NY-ESO-1 vaccines induce both humoral and cellular NY-ESO-1-specific immune responses in cancer patients
    • Jager E, Karbach J, Gnjatic S et al. Recombinant vaccinia/fowlpox NY-ESO-1 vaccines induce both humoral and cellular NY-ESO-1-specific immune responses in cancer patients. Proc. Natl Acad. Sci. USA 103(39), 14453-14458 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , Issue.39 , pp. 14453-14458
    • Jager, E.1    Karbach, J.2    Gnjatic, S.3
  • 25
    • 84859588335 scopus 로고    scopus 로고
    • Efficacy of vaccination with recombinant vaccinia and fowlpox vectors expressing NY-ESO-1 antigen in ovarian cancer and melanoma patients
    • Odunsi K, Matsuzaki J, Karbach J et al. Efficacy of vaccination with recombinant vaccinia and fowlpox vectors expressing NY-ESO-1 antigen in ovarian cancer and melanoma patients. Proc. Natl Acad. Sci. USA 109(15), 5797-5802 (2012).
    • (2012) Proc. Natl Acad. Sci. USA , vol.109 , Issue.15 , pp. 5797-5802
    • Odunsi, K.1    Matsuzaki, J.2    Karbach, J.3
  • 26
    • 84894106057 scopus 로고    scopus 로고
    • Epigenetic potentiation of NY-ESO-1 vaccine therapy in human ovarian cancer
    • Odunsi K, Matsuzaki J, James SR et al. Epigenetic potentiation of NY-ESO-1 vaccine therapy in human ovarian cancer. Cancer Immunol. Res. 2(1), 37-49 (2014).
    • (2014) Cancer Immunol. Res. , vol.2 , Issue.1 , pp. 37-49
    • Odunsi, K.1    Matsuzaki, J.2    James, S.R.3
  • 27
    • 41149160918 scopus 로고    scopus 로고
    • Antigen-specific immunotherapy of cervical and ovarian cancer
    • Hung CF, Wu TC, Monie A, Roden R. Antigen-specific immunotherapy of cervical and ovarian cancer. Immunol. Rev. 222, 43-69 (2008).
    • (2008) Immunol. Rev. , vol.222 , pp. 43-69
    • Hung, C.F.1    Wu, T.C.2    Monie, A.3    Roden, R.4
  • 29
    • 33644854425 scopus 로고    scopus 로고
    • Antibody immunity to the p53 oncogenic protein is a prognostic indicator in ovarian cancer
    • Goodell V, Salazar LG, Urban N et al. Antibody immunity to the p53 oncogenic protein is a prognostic indicator in ovarian cancer. J. Clin. Oncol. 24(5), 762-768 (2006).
    • (2006) J. Clin. Oncol. , vol.24 , Issue.5 , pp. 762-768
    • Goodell, V.1    Salazar, L.G.2    Urban, N.3
  • 30
    • 84860790830 scopus 로고    scopus 로고
    • A gynecologic oncology group PhaseII trial of two p53 peptide vaccine approaches: Subcutaneous injection and intravenous pulsed dendritic cells in high recurrence risk ovarian cancer patients
    • Rahma OE, Ashtar E, Czystowska M et al. A Gynecologic Oncology group PhaseII trial of two p53 peptide vaccine approaches: subcutaneous injection and intravenous pulsed dendritic cells in high recurrence risk ovarian cancer patients. Cancer Immunl. Immunother. 61(3), 373-384 (2012).
    • (2012) Cancer Immunl. Immunother. , vol.61 , Issue.3 , pp. 373-384
    • Rahma, O.E.1    Ashtar, E.2    Czystowska, M.3
  • 31
    • 33646895848 scopus 로고    scopus 로고
    • Immunohistochemical detection of WT1 protein in a variety of cancer cells
    • Nakatsuka S, Oji Y, Horiuchi T et al. Immunohistochemical detection of WT1 protein in a variety of cancer cells. Mod. Pathol. 19(6), 804-814 (2006).
    • (2006) Mod. Pathol. , vol.19 , Issue.6 , pp. 804-814
    • Nakatsuka, S.1    Oji, Y.2    Horiuchi, T.3
  • 32
    • 33846786653 scopus 로고    scopus 로고
    • In ovarian cancer the prognostic influence of HER2/neu is not dependent on the CXCR4/SDF-1 signalling pathway
    • Pils D, Pinter A, Reibenwein J et al. In ovarian cancer the prognostic influence of HER2/neu is not dependent on the CXCR4/SDF-1 signalling pathway. Br. J. Cancer 96(3), 485-491 (2007).
    • (2007) Br. J. Cancer , vol.96 , Issue.3 , pp. 485-491
    • Pils, D.1    Pinter, A.2    Reibenwein, J.3
  • 33
    • 0035113705 scopus 로고    scopus 로고
    • Immunization with a HER-2/neu helper peptide vaccine generates HER-2/neu CD8 T-cell immunity in cancer patients
    • Knutson KL, Schiffman K, Disis ML. Immunization with a HER-2/neu helper peptide vaccine generates HER-2/neu CD8 T-cell immunity in cancer patients. J. Clin. Invest. 107(4), 477-484 (2001).
    • (2001) J. Clin. Invest. , vol.107 , Issue.4 , pp. 477-484
    • Knutson, K.L.1    Schiffman, K.2    Disis, M.L.3
  • 34
    • 0042347518 scopus 로고    scopus 로고
    • Wilms tumor gene peptide-based immunotherapy for patients with overt leukemia from myelodysplastic syndrome (MDS) or MDS with myelofibrosis
    • Oka Y, Tsuboi A, Murakami M et al. Wilms tumor gene peptide-based immunotherapy for patients with overt leukemia from myelodysplastic syndrome (MDS) or MDS with myelofibrosis. Int. J. Hematol. 78(1), 56-61 (2003).
    • (2003) Int. J. Hematol. , vol.78 , Issue.1 , pp. 56-61
    • Oka, Y.1    Tsuboi, A.2    Murakami, M.3
  • 35
    • 4644289323 scopus 로고    scopus 로고
    • Induction of WT1 (Wilms' tumor gene)-specific cytotoxic T lymphocytes by WT1 peptide vaccine and the resultant cancer regression
    • Oka Y, Tsuboi A, Taguchi T et al. Induction of WT1 (Wilms' tumor gene)-specific cytotoxic T lymphocytes by WT1 peptide vaccine and the resultant cancer regression. Proc. Natl Acad. Sci. USA 101(38), 13885-13890 (2004).
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , Issue.38 , pp. 13885-13890
    • Oka, Y.1    Tsuboi, A.2    Taguchi, T.3
  • 36
    • 12144291167 scopus 로고    scopus 로고
    • WT1 peptide-based immunotherapy for patients with lung cancer: Report of two cases
    • Tsuboi A, Oka Y, Osaki T et al. WT1 peptide-based immunotherapy for patients with lung cancer: report of two cases. Microbiol. Immunol. 48(3), 175-184 (2004).
    • (2004) Microbiol. Immunol. , vol.48 , Issue.3 , pp. 175-184
    • Tsuboi, A.1    Oka, Y.2    Osaki, T.3
  • 37
    • 43249090418 scopus 로고    scopus 로고
    • PhaseII clinical trial of Wilms tumor 1 peptide vaccination for patients with recurrent glioblastoma multiforme
    • Izumoto S, Tsuboi A, Oka Y et al. PhaseII clinical trial of Wilms tumor 1 peptide vaccination for patients with recurrent glioblastoma multiforme. J. Neurosurg. 108(5), 963-971 (2008).
    • (2008) J. Neurosurg. , vol.108 , Issue.5 , pp. 963-971
    • Izumoto, S.1    Tsuboi, A.2    Oka, Y.3
  • 38
    • 75149119734 scopus 로고    scopus 로고
    • Wilms' tumor 1 (WT1) peptide immunotherapy for gynecological malignancy
    • Ohno S, Kyo S, Myojo S et al. Wilms' tumor 1 (WT1) peptide immunotherapy for gynecological malignancy. Anticancer Res. 29(11), 4779-4784 (2009).
    • (2009) Anticancer Res. , vol.29 , Issue.11 , pp. 4779-4784
    • Ohno, S.1    Kyo, S.2    Myojo, S.3
  • 39
    • 79961175455 scopus 로고    scopus 로고
    • WT1 peptide vaccine stabilized intractable ovarian cancer patient for one year: A case report
    • Dohi S, Ohno S, Ohno Y et al. WT1 peptide vaccine stabilized intractable ovarian cancer patient for one year: a case report. Anticancer Res. 31(7), 2441-2445 (2011).
    • (2011) Anticancer Res. , vol.31 , Issue.7 , pp. 2441-2445
    • Dohi, S.1    Ohno, S.2    Ohno, Y.3
  • 40
    • 77957874437 scopus 로고    scopus 로고
    • Potential target antigens for a universal vaccine in epithelial ovarian cancer
    • (Epub ahead of print)
    • Vermeij R, Daemen T, De Bock GH et al. Potential target antigens for a universal vaccine in epithelial ovarian cancer. Clin. Dev. Immunol. doi: 10.1155/2010/891505. (2010) (Epub ahead of print).
    • (2010) Clin. Dev. Immunol.
    • Vermeij, R.1    Daemen, T.2    De Bock, G.H.3
  • 41
    • 0034962599 scopus 로고    scopus 로고
    • Induction of tcell responses against autologous ovarian tumors with whole tumor cell lysate-pulsed dendritic cells
    • Zhao X, Wei YQ, Peng ZL. Induction of Tcell responses against autologous ovarian tumors with whole tumor cell lysate-pulsed dendritic cells. Immunol. Invest. 30(1), 33-45 (2001).
    • (2001) Immunol. Invest. , vol.30 , Issue.1 , pp. 33-45
    • Zhao, X.1    Wei, Y.Q.2    Peng, Z.L.3
  • 42
    • 0036181959 scopus 로고    scopus 로고
    • Vaccination with autologous tumour antigen-pulsed dendritic cells in advanced gynaecological malignancies: Clinical and immunological evaluation of a Phase I trial
    • Hernando JJ, Park TW, Kubler K, Offergeld R, Schlebusch H, Bauknecht T. Vaccination with autologous tumour antigen-pulsed dendritic cells in advanced gynaecological malignancies: clinical and immunological evaluation of a Phase I trial. Cancer Immunol. Immunother. 51(1), 45-52 (2002).
    • (2002) Cancer Immunol. Immunother. , vol.51 , Issue.1 , pp. 45-52
    • Hernando, J.J.1    Park, T.W.2    Kubler, K.3    Offergeld, R.4    Schlebusch, H.5    Bauknecht, T.6
  • 43
    • 84879045776 scopus 로고    scopus 로고
    • A PhaseI vaccine trial using dendritic cells pulsed with autologous oxidized lysate for recurrent ovarian cancer
    • Kandalaft LE, Chiang CL, Tanyi J et al. A PhaseI vaccine trial using dendritic cells pulsed with autologous oxidized lysate for recurrent ovarian cancer. J. Transl. Med. 11, 149 (2013).
    • (2013) J. Transl. Med. , vol.11 , pp. 149
    • Kandalaft, L.E.1    Chiang, C.L.2    Tanyi, J.3
  • 44
    • 84894526212 scopus 로고    scopus 로고
    • Isolation and characterization of cancer stem cells from high-grade serous ovarian carcinomas Cell
    • He QZ, Luo XZ, Wang K et al. Isolation and characterization of cancer stem cells from high-grade serous ovarian carcinomas Cell. Physiol. Biochem. 33(1), 173-184 (2014).
    • (2014) Physiol. Biochem. , vol.33 , Issue.1 , pp. 173-184
    • He, Q.Z.1    Luo, X.Z.2    Wang, K.3
  • 45
    • 2342535230 scopus 로고    scopus 로고
    • Cancer stem cells: Are we missing the target?
    • Jones RJ, Matsui WH, Smith BD. Cancer stem cells: are we missing the target? J. Natl Cancer Inst. 96(8), 583-585 (2004).
    • (2004) J. Natl Cancer Inst. , vol.96 , Issue.8 , pp. 583-585
    • Jones, R.J.1    Matsui, W.H.2    Smith, B.D.3
  • 46
    • 84872375754 scopus 로고    scopus 로고
    • Cells, stem cells, and cancer stem cells
    • Aguilar-Gallardo C, Simon C. Cells, stem cells, and cancer stem cells. Semin. Reprod. Med. 31(1), 5-13 (2013).
    • (2013) Semin. Reprod. Med. , vol.31 , Issue.1 , pp. 5-13
    • Aguilar-Gallardo, C.1    Simon, C.2
  • 47
    • 84873164609 scopus 로고    scopus 로고
    • Vaccination with embryonic stem cells generates effective antitumor immunity against ovarian cancer
    • Zhang Z, Chen X, Chang X, Ye X, Li Y, Cui H. Vaccination with embryonic stem cells generates effective antitumor immunity against ovarian cancer. Int. J. Mol. Med. 31(1), 147-153 (2013).
    • (2013) Int. J. Mol. Med. , vol.31 , Issue.1 , pp. 147-153
    • Zhang, Z.1    Chen, X.2    Chang, X.3    Ye, X.4    Li, Y.5    Cui, H.6
  • 48
    • 0016756272 scopus 로고
    • Continuous cultures of fused cells secreting antibody of predefined specificity
    • Kohler G, Milstein C. Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 256(5517), 495-497 (1975).
    • (1975) Nature , vol.256 , Issue.5517 , pp. 495-497
    • Kohler, G.1    Milstein, C.2
  • 49
    • 84885760228 scopus 로고    scopus 로고
    • Blocking the B7-H4 pathway with novel recombinant antibodies enhances Tcell-mediated antitumor responses
    • Dangaj D, Scholler N. Blocking the B7-H4 pathway with novel recombinant antibodies enhances Tcell-mediated antitumor responses. Oncoimmunology 2(8), e25913 (2013).
    • (2013) Oncoimmunology , vol.2 , Issue.8 , pp. e25913
    • Dangaj, D.1    Scholler, N.2
  • 50
    • 84880381830 scopus 로고    scopus 로고
    • The costimulatory molecule B7-H4 promote tumor progression and cell proliferation through translocating into nucleus
    • Zhang L, Wu H, Lu D et al. The costimulatory molecule B7-H4 promote tumor progression and cell proliferation through translocating into nucleus. Oncogene 32(46), 5347-5358 (2013).
    • (2013) Oncogene , vol.32 , Issue.46 , pp. 5347-5358
    • Zhang, L.1    Wu, H.2    Lu, D.3
  • 51
    • 0028144072 scopus 로고
    • Evidence for a role of the epithelial glycoprotein40 (Ep-CAM) in epithelial cell-cell adhesion
    • Litvinov SV, Bakker HA, Gourevitch MM, Velders MP, Warnaar SO. Evidence for a role of the epithelial glycoprotein40 (Ep-CAM) in epithelial cell-cell adhesion. Cell Adhes. Commun. 2(5), 417-428 (1994).
    • (1994) Cell Adhes. Commun. , vol.2 , Issue.5 , pp. 417-428
    • Litvinov, S.V.1    Bakker, H.A.2    Gourevitch, M.M.3    Velders, M.P.4    Warnaar, S.O.5
  • 52
    • 0034627152 scopus 로고    scopus 로고
    • Ep-CAM overexpression in breast cancer as a predictor of survival
    • Gastl G, Spizzo G, Obrist P, Dunser M, Mikuz G. Ep-CAM overexpression in breast cancer as a predictor of survival. Lancet 356(9246), 1981-1982 (2000).
    • (2000) Lancet , vol.356 , Issue.9246 , pp. 1981-1982
    • Gastl, G.1    Spizzo, G.2    Obrist, P.3    Dunser, M.4    Mikuz, G.5
  • 53
    • 33750165279 scopus 로고    scopus 로고
    • Overexpression of epithelial cell adhesion molecule (Ep-CAM) is an independent prognostic marker for reduced survival of patients with epithelial ovarian cancer
    • Spizzo G, Went P, Dirnhofer S et al. Overexpression of epithelial cell adhesion molecule (Ep-CAM) is an independent prognostic marker for reduced survival of patients with epithelial ovarian cancer. Gynecol. Oncol. 103(2), 483-488 (2006).
    • (2006) Gynecol. Oncol. , vol.103 , Issue.2 , pp. 483-488
    • Spizzo, G.1    Went, P.2    Dirnhofer, S.3
  • 54
    • 58149489177 scopus 로고    scopus 로고
    • Ovarian carcinoma subtypes are different diseases: Implications for biomarker studies
    • Kobel M, Kalloger SE, Boyd N et al. Ovarian carcinoma subtypes are different diseases: implications for biomarker studies. PLoS Med. 5(12), e232 (2008).
    • (2008) PLoS Med. , vol.5 , Issue.12 , pp. e232
    • Kobel, M.1    Kalloger, S.E.2    Boyd, N.3
  • 55
    • 69449087383 scopus 로고    scopus 로고
    • Overexpression of epithelial cell adhesion molecule in primary, metastatic, and recurrent/chemotherapy-resistant epithelial ovarian cancer: Implications for epithelial cell adhesion molecule-specific immunotherapy
    • Bellone S, Siegel ER, Cocco E et al. Overexpression of epithelial cell adhesion molecule in primary, metastatic, and recurrent/chemotherapy-resistant epithelial ovarian cancer: implications for epithelial cell adhesion molecule-specific immunotherapy. Int. J. Gynecol. Cancer 19(5), 860-866 (2009).
    • (2009) Int. J. Gynecol. Cancer , vol.19 , Issue.5 , pp. 860-866
    • Bellone, S.1    Siegel, E.R.2    Cocco, E.3
  • 56
    • 0023680745 scopus 로고
    • Immunohistochemical monitoring of metastatic colorectal carcinoma in patients treated with monoclonal antibodies (MAb 17-1A)
    • Shetye J, Frodin JE, Christensson B et al. Immunohistochemical monitoring of metastatic colorectal carcinoma in patients treated with monoclonal antibodies (MAb 17-1A). Cancer Immunol. Immunother. 27(2), 154-162 (1988).
    • (1988) Cancer Immunol. Immunother. , vol.27 , Issue.2 , pp. 154-162
    • Shetye, J.1    Frodin, J.E.2    Christensson, B.3
  • 57
    • 0035889129 scopus 로고    scopus 로고
    • Induction of a long-lasting antitumor immunity by a trifunctional bispecific antibody
    • Ruf P, Lindhofer H. Induction of a long-lasting antitumor immunity by a trifunctional bispecific antibody. Blood 98(8), 2526-2534 (2001).
    • (2001) Blood , vol.98 , Issue.8 , pp. 2526-2534
    • Ruf, P.1    Lindhofer, H.2
  • 58
    • 0034051390 scopus 로고    scopus 로고
    • The Fc-region of a new class of intact bispecific antibody mediates activation of accessory cells and NK cells and induces direct phagocytosis of tumour cells
    • Zeidler R, Mysliwietz J, Csanady M et al. The Fc-region of a new class of intact bispecific antibody mediates activation of accessory cells and NK cells and induces direct phagocytosis of tumour cells. Br. J. Cancer 83(2), 261-266 (2000).
    • (2000) Br. J. Cancer , vol.83 , Issue.2 , pp. 261-266
    • Zeidler, R.1    Mysliwietz, J.2    Csanady, M.3
  • 59
    • 84865115651 scopus 로고    scopus 로고
    • Trifunctional bispecific antibodies induce tumor-specific T cells and elicit a vaccination effect
    • Eissler N, Ruf P, Mysliwietz J, Lindhofer H, Mocikat R. Trifunctional bispecific antibodies induce tumor-specific T cells and elicit a vaccination effect. Cancer Res. 72(16), 3958-3966 (2012).
    • (2012) Cancer Res. , vol.72 , Issue.16 , pp. 3958-3966
    • Eissler, N.1    Ruf, P.2    Mysliwietz, J.3    Lindhofer, H.4    Mocikat, R.5
  • 60
    • 77954676136 scopus 로고    scopus 로고
    • The trifunctional antibody catumaxomab for the treatment of malignant ascites due to epithelial cancer: Results of a prospective randomized Phase II/III trial
    • Heiss MM, Murawa P, Koralewski P et al. The trifunctional antibody catumaxomab for the treatment of malignant ascites due to epithelial cancer: results of a prospective randomized Phase II/III trial. Int. J. Cancer 127(9), 2209-2221 (2010).
    • (2010) Int. J. Cancer , vol.127 , Issue.9 , pp. 2209-2221
    • Heiss, M.M.1    Murawa, P.2    Koralewski, P.3
  • 61
    • 84919827483 scopus 로고    scopus 로고
    • A Phase I study of EpCAM/CD3-bispecific antibody (MT110) in patients with advanced solid tumors. Oral Abstract Session, Developmental Therapeutics - Clinical Pharmacology and Immunotherapy
    • Chicago, IL, USA, 1-5 June
    • Walter M. Fiedler MW, Maxim Kebenko et al. A Phase I study of EpCAM/CD3-bispecific antibody (MT110) in patients with advanced solid tumors. Oral Abstract Session, Developmental Therapeutics - Clinical Pharmacology and Immunotherapy. Presented at: 2012 ASCO Annual Meeting. Chicago, IL, USA, 1-5 June2012
    • (2012) Presented at: 2012 ASCO Annual Meeting
    • Walter, M.1    Fiedler, M.W.2    Kebenko, M.3
  • 62
    • 34447132202 scopus 로고    scopus 로고
    • Effective relief of malignant ascites in patients with advanced ovarian cancer by a trifunctional anti-EpCAM x anti-CD3 antibody: A Phase I/II study
    • Burges A, Wimberger P, Kumper C et al. Effective relief of malignant ascites in patients with advanced ovarian cancer by a trifunctional anti-EpCAM x anti-CD3 antibody: a Phase I/II study. Clin. Cancer Res. 13(13), 3899-3905 (2007).
    • (2007) Clin. Cancer Res. , vol.13 , Issue.13 , pp. 3899-3905
    • Burges, A.1    Wimberger, P.2    Kumper, C.3
  • 63
    • 77954017982 scopus 로고    scopus 로고
    • CA 125 and the detection of recurrent ovarian cancer: A reasonably accurate biomarker for a difficult disease
    • Bast RC, Jr. CA 125 and the detection of recurrent ovarian cancer: a reasonably accurate biomarker for a difficult disease. Cancer 116(12), 2850-2853 (2010).
    • (2010) Cancer , vol.116 , Issue.12 , pp. 2850-2853
    • Bast, R.C.1
  • 64
    • 0035886979 scopus 로고    scopus 로고
    • Use of CA-125 to define progression of ovarian cancer in patients with persistently elevated levels
    • Rustin GJ, Marples M, Nelstrop AE, Mahmoudi M, Meyer T. Use of CA-125 to define progression of ovarian cancer in patients with persistently elevated levels. J. Clin. Oncol. 19(20), 4054-4057 (2001).
    • (2001) J. Clin. Oncol. , vol.19 , Issue.20 , pp. 4054-4057
    • Rustin, G.J.1    Marples, M.2    Nelstrop, A.E.3    Mahmoudi, M.4    Meyer, T.5
  • 65
    • 28044467326 scopus 로고    scopus 로고
    • Potent suppression of natural killer cell response mediated by the ovarian tumor marker CA125
    • Patankar MS, Jing Y, Morrison JC et al. Potent suppression of natural killer cell response mediated by the ovarian tumor marker CA125. Gynecol. Oncol. 99(3), 704-713 (2005).
    • (2005) Gynecol. Oncol. , vol.99 , Issue.3 , pp. 704-713
    • Patankar, M.S.1    Jing, Y.2    Morrison, J.C.3
  • 66
    • 0030888481 scopus 로고    scopus 로고
    • Immunological responses to the tumor-associated antigen CA125 in patients with advanced ovarian cancer induced by the murine monoclonal anti-idiotype vaccine ACA125
    • Wagner U, Schlebusch H, Kohler S, Schmolling J, Grunn U, Krebs D. Immunological responses to the tumor-associated antigen CA125 in patients with advanced ovarian cancer induced by the murine monoclonal anti-idiotype vaccine ACA125. Hybridoma 16(1), 33-40 (1997).
    • (1997) Hybridoma , vol.16 , Issue.1 , pp. 33-40
    • Wagner, U.1    Schlebusch, H.2    Kohler, S.3    Schmolling, J.4    Grunn, U.5    Krebs, D.6
  • 67
    • 0033062666 scopus 로고    scopus 로고
    • Evaluation of immunological responses in patients with ovarian cancer treated with the anti-idiotype vaccine ACA125 by determination of intracellular cytokines - A preliminary report
    • Reinartz S, Boerner H, Koehler S, Von Ruecker A, Schlebusch H, Wagner U. Evaluation of immunological responses in patients with ovarian cancer treated with the anti-idiotype vaccine ACA125 by determination of intracellular cytokines - a preliminary report. Hybridoma 18(1), 41-45 (1999).
    • (1999) Hybridoma , vol.18 , Issue.1 , pp. 41-45
    • Reinartz, S.1    Boerner, H.2    Koehler, S.3    Von Ruecker, A.4    Schlebusch, H.5    Wagner, U.6
  • 68
    • 12144287745 scopus 로고    scopus 로고
    • Vaccination of patients with advanced ovarian carcinoma with the anti-idiotype ACA125: Immunological response and survival (Phase Ib/II)
    • Reinartz S, Kohler S, Schlebusch H et al. Vaccination of patients with advanced ovarian carcinoma with the anti-idiotype ACA125: immunological response and survival (Phase Ib/II). Clin. Cancer Res. 10(5), 1580-1587 (2004).
    • (2004) Clin. Cancer Res. , vol.10 , Issue.5 , pp. 1580-1587
    • Reinartz, S.1    Kohler, S.2    Schlebusch, H.3
  • 69
    • 33749663630 scopus 로고    scopus 로고
    • The anti-idiotypic antibody abagovomab in patients with recurrent ovarian cancer. A Phase I trial of the AGO-OVAR
    • Pfisterer J, Du Bois A, Sehouli J et al. The anti-idiotypic antibody abagovomab in patients with recurrent ovarian cancer. A Phase I trial of the AGO-OVAR. Ann. Oncol. 17(10), 1568-1577 (2006).
    • (2006) Ann. Oncol. , vol.17 , Issue.10 , pp. 1568-1577
    • Pfisterer, J.1    Du Bois, A.2    Sehouli, J.3
  • 70
    • 84876529191 scopus 로고    scopus 로고
    • Abagovomab as maintenance therapy in patients with epithelial ovarian cancer: A Phase III trial of the AGO OVAR, COGI, GINECO, and GEICO - The MIMOSA study
    • Sabbatini P, Harter P, Scambia G et al. Abagovomab as maintenance therapy in patients with epithelial ovarian cancer: a Phase III trial of the AGO OVAR, COGI, GINECO, and GEICO - the MIMOSA study. J. Clin. Oncol. 31(12), 1554-1561 (2013).
    • (2013) J. Clin. Oncol. , vol.31 , Issue.12 , pp. 1554-1561
    • Sabbatini, P.1    Harter, P.2    Scambia, G.3
  • 71
    • 0038336598 scopus 로고    scopus 로고
    • Immune responses to murine monoclonal antibody-B43.13 correlate with prolonged survival of women with recurrent ovarian cancer
    • Mobus VJ, Baum RP, Bolle M et al. Immune responses to murine monoclonal antibody-B43.13 correlate with prolonged survival of women with recurrent ovarian cancer. Am. J. Obstet. Gynecol. 189(1), 28-36 (2003).
    • (2003) Am. J. Obstet. Gynecol. , vol.189 , Issue.1 , pp. 28-36
    • Mobus, V.J.1    Baum, R.P.2    Bolle, M.3
  • 72
    • 0034947607 scopus 로고    scopus 로고
    • Induction of CA125-specific B and Tcell responses in patients injected with MAb-B43.13-evidence for antibody-mediated antigen-processing and presentation of CA125 invivo
    • Noujaim AA, Schultes BC, Baum RP, Madiyalakan R. Induction of CA125-specific B and Tcell responses in patients injected with MAb-B43.13-evidence for antibody-mediated antigen-processing and presentation of CA125 invivo. Cancer Biother. Radiopharm. 16(3), 187-203 (2001).
    • (2001) Cancer Biother. Radiopharm. , vol.16 , Issue.3 , pp. 187-203
    • Noujaim, A.A.1    Schultes, B.C.2    Baum, R.P.3    Madiyalakan, R.4
  • 73
    • 65549085361 scopus 로고    scopus 로고
    • The immune adjuvant properties of front-line carboplatin-paclitaxel: A randomized Phase 2 study of alternative schedules of intravenous oregovomab chemoimmunotherapy in advanced ovarian cancer
    • Braly P, Nicodemus CF, Chu C et al. The Immune adjuvant properties of front-line carboplatin-paclitaxel: a randomized Phase 2 study of alternative schedules of intravenous oregovomab chemoimmunotherapy in advanced ovarian cancer. J. Immunother. 32(1), 54-65 (2009).
    • (2009) J. Immunother. , vol.32 , Issue.1 , pp. 54-65
    • Braly, P.1    Nicodemus, C.F.2    Chu, C.3
  • 74
    • 33847368549 scopus 로고    scopus 로고
    • Metronomic cyclophosphamide regimen selectively depletes CD4+CD25+ regulatory Tcells and restores T and NK effector functions in end stage cancer patients
    • Ghiringhelli F, Menard C, Puig PE et al. Metronomic cyclophosphamide regimen selectively depletes CD4+CD25+ regulatory Tcells and restores T and NK effector functions in end stage cancer patients. Cancer Immunol. Immunother. 56(5), 641-648 (2007).
    • (2007) Cancer Immunol. Immunother. , vol.56 , Issue.5 , pp. 641-648
    • Ghiringhelli, F.1    Menard, C.2    Puig, P.E.3
  • 75
    • 84874820023 scopus 로고    scopus 로고
    • The role of mesothelin in tumor progression and targeted therapy
    • Tang Z, Qian M, Ho M. The role of mesothelin in tumor progression and targeted therapy. Anticancer Agents Med. Chem. 13(2), 276-280 (2013).
    • (2013) Anticancer Agents Med. Chem. , vol.13 , Issue.2 , pp. 276-280
    • Tang, Z.1    Qian, M.2    Ho, M.3
  • 76
    • 84902687265 scopus 로고    scopus 로고
    • Anetumab ravtansine: A novel mesothelin-targeting antibody-drug conjugate cures tumors with heterogeneous target expression favored by bystander effect
    • Golfier S, Kopitz C, Kahnert A et al. Anetumab ravtansine: a novel mesothelin-targeting antibody-drug conjugate cures tumors with heterogeneous target expression favored by bystander effect. Mol. Cancer Ther. 13(6), 1537-48 (2014).
    • (2014) Mol. Cancer Ther. , vol.13 , Issue.6 , pp. 1537-1548
    • Golfier, S.1    Kopitz, C.2    Kahnert, A.3
  • 77
    • 2442484053 scopus 로고    scopus 로고
    • + regulatory t cells for immunologic self-tolerance and negative control of immune responses
    • + regulatory t cells for immunologic self-tolerance and negative control of immune responses. Annu. Rev. Immunol. 22, 531-562 (2004).
    • (2004) Annu. Rev. Immunol. , vol.22 , pp. 531-562
    • Sakaguchi, S.1
  • 78
    • 28644447974 scopus 로고    scopus 로고
    • Regulatory T cells in ovarian cancer: Biology and therapeutic potential
    • Barnett B, Kryczek I, Cheng P, Zou W, Curiel TJ. Regulatory T cells in ovarian cancer: biology and therapeutic potential. Am. J. Reprod. Immunol. 54(6), 369-377 (2005).
    • (2005) Am. J. Reprod. Immunol. , vol.54 , Issue.6 , pp. 369-377
    • Barnett, B.1    Kryczek, I.2    Cheng, P.3    Zou, W.4    Curiel, T.J.5
  • 79
    • 75749125293 scopus 로고    scopus 로고
    • Ovarian cancer tumor infiltrating T-regulatory (T(reg)) cells are associated with a metastatic phenotype
    • Barnett JC, Bean SM, Whitaker RS et al. Ovarian cancer tumor infiltrating T-regulatory (T(reg)) cells are associated with a metastatic phenotype. Gynecol. Oncol. 116(3), 556-562 (2010).
    • (2010) Gynecol. Oncol. , vol.116 , Issue.3 , pp. 556-562
    • Barnett, J.C.1    Bean, S.M.2    Whitaker, R.S.3
  • 80
    • 79958293766 scopus 로고    scopus 로고
    • The suppressive tumor microenvironment: A challenge in cancer immunotherapy
    • Vasievich EA, Huang L. The suppressive tumor microenvironment: a challenge in cancer immunotherapy. Mol. Pharm. 8(3), 635-641 (2011).
    • (2011) Mol. Pharm. , vol.8 , Issue.3 , pp. 635-641
    • Vasievich, E.A.1    Huang, L.2
  • 81
    • 34247504608 scopus 로고    scopus 로고
    • + human regulatory Tcells invivo: Kinetics of Treg depletion and alterations in immune functions invivo and invitro
    • + human regulatory Tcells invivo: kinetics of Treg depletion and alterations in immune functions invivo and invitro. Int. J. Cancer 120(12), 2723-2733 (2007).
    • (2007) Int. J. Cancer , vol.120 , Issue.12 , pp. 2723-2733
    • Mahnke, K.1    Schonfeld, K.2    Fondel, S.3
  • 82
    • 78449258549 scopus 로고    scopus 로고
    • Development of ipilimumab: Contribution to a new paradigm for cancer immunotherapy
    • Hoos A, Ibrahim R, Korman A et al. Development of ipilimumab: contribution to a new paradigm for cancer immunotherapy. Semin. Oncol. 37(5), 533-546 (2010).
    • (2010) Semin. Oncol. , vol.37 , Issue.5 , pp. 533-546
    • Hoos, A.1    Ibrahim, R.2    Korman, A.3
  • 84
    • 33744792341 scopus 로고    scopus 로고
    • Enterocolitis in patients with cancer after antibody blockade of cytotoxic T-lymphocyte-associated antigen 4
    • Beck KE, Blansfield JA, Tran KQ et al. Enterocolitis in patients with cancer after antibody blockade of cytotoxic T-lymphocyte-associated antigen 4. J. Clin. Oncol. 24(15), 2283-2289 (2006).
    • (2006) J. Clin. Oncol. , vol.24 , Issue.15 , pp. 2283-2289
    • Beck, K.E.1    Blansfield, J.A.2    Tran, K.Q.3
  • 85
    • 84897854198 scopus 로고    scopus 로고
    • PD-1 blockade and OX40 triggering synergistically protects against tumor growth in a murine model of ovarian cancer
    • Guo Z, Wang X, Cheng D, Xia Z, Luan M, Zhang S. PD-1 blockade and OX40 triggering synergistically protects against tumor growth in a murine model of ovarian cancer. PLoS ONE 9(2), e89350 (2014).
    • (2014) PLoS ONE , vol.9 , Issue.2 , pp. e89350
    • Guo, Z.1    Wang, X.2    Cheng, D.3    Xia, Z.4    Luan, M.5    Zhang, S.6
  • 86
    • 17144445438 scopus 로고    scopus 로고
    • A step further in understanding the biology of the folate receptor in ovarian carcinoma
    • Bagnoli M, Canevari S, Figini M et al. A step further in understanding the biology of the folate receptor in ovarian carcinoma. Gynecol. Oncol. 88(1 Pt 2), S140-S144 (2003).
    • (2003) Gynecol. Oncol. , vol.88 , Issue.1 , pp. S140-S144
    • Bagnoli, M.1    Canevari, S.2    Figini, M.3
  • 87
    • 84877579319 scopus 로고    scopus 로고
    • Farletuzumab (a monoclonal antibody against folate receptor alpha) in relapsed platinum-sensitive ovarian cancer
    • Armstrong DK, White AJ, Weil SC, Phillips M, Coleman RL. Farletuzumab (a monoclonal antibody against folate receptor alpha) in relapsed platinum-sensitive ovarian cancer. Gynecol. Oncol. 129(3), 452-458 (2013).
    • (2013) Gynecol. Oncol. , vol.129 , Issue.3 , pp. 452-458
    • Armstrong, D.K.1    White, A.J.2    Weil, S.C.3    Phillips, M.4    Coleman, R.L.5
  • 88
    • 84858758766 scopus 로고    scopus 로고
    • Adoptive immunotherapy for cancer: Harnessing the Tcell response
    • Restifo NP, Dudley ME, Rosenberg SA. Adoptive immunotherapy for cancer: harnessing the Tcell response. Nat. Rev. Immunol. 12(4), 269-281 (2012).
    • (2012) Nat. Rev. Immunol. , vol.12 , Issue.4 , pp. 269-281
    • Restifo, N.P.1    Dudley, M.E.2    Rosenberg, S.A.3
  • 89
    • 55949125601 scopus 로고    scopus 로고
    • Adoptive cell therapy for patients with metastatic melanoma: Evaluation of intensive myeloablative chemoradiation preparative regimens
    • Dudley ME, Yang JC, Sherry R et al. Adoptive cell therapy for patients with metastatic melanoma: evaluation of intensive myeloablative chemoradiation preparative regimens. J. Clin. Oncol. 26(32), 5233-5239 (2008).
    • (2008) J. Clin. Oncol. , vol.26 , Issue.32 , pp. 5233-5239
    • Dudley, M.E.1    Yang, J.C.2    Sherry, R.3
  • 90
    • 70349561448 scopus 로고    scopus 로고
    • PD-1/PD-L1 interactions inhibit antitumor immune responses in a murine acute myeloid leukemia model
    • Zhang L, Gajewski TF, Kline J. PD-1/PD-L1 interactions inhibit antitumor immune responses in a murine acute myeloid leukemia model. Blood 114(8), 1545-1552 (2009).
    • (2009) Blood , vol.114 , Issue.8 , pp. 1545-1552
    • Zhang, L.1    Gajewski, T.F.2    Kline, J.3
  • 91
    • 68349146143 scopus 로고    scopus 로고
    • New perspectives for melanoma immunotherapy: Role of IL-12
    • Cocco C, Pistoia V, Airoldi I. New perspectives for melanoma immunotherapy: role of IL-12. Curr. Mol. Med. 9(4), 459-469 (2009).
    • (2009) Curr. Mol. Med. , vol.9 , Issue.4 , pp. 459-469
    • Cocco, C.1    Pistoia, V.2    Airoldi, I.3
  • 92
    • 59849106610 scopus 로고    scopus 로고
    • Sperm protein 17 is a suitable target for adoptive T-cell-based immunotherapy in human ovarian cancer
    • Chiriva-Internati M, Weidanz JA, Yu Y et al. Sperm protein 17 is a suitable target for adoptive T-cell-based immunotherapy in human ovarian cancer. J. Immunother. 31(8), 693-703 (2008).
    • (2008) J. Immunother. , vol.31 , Issue.8 , pp. 693-703
    • Chiriva-Internati, M.1    Weidanz, J.A.2    Yu, Y.3
  • 93
    • 60849121727 scopus 로고    scopus 로고
    • Induction of human tumor-associated differentially expressed gene-12 (TADG-12/TMPRSS3)-specific cytotoxic T lymphocytes in human lymphocyte antigen-A2.1-positive healthy donors and patients with advanced ovarian cancer
    • Bellone S, Anfossi S, O'brien TJ et al. Induction of human tumor-associated differentially expressed gene-12 (TADG-12/TMPRSS3)-specific cytotoxic T lymphocytes in human lymphocyte antigen-A2.1-positive healthy donors and patients with advanced ovarian cancer. Cancer 115(4), 800-811 (2009).
    • (2009) Cancer , vol.115 , Issue.4 , pp. 800-811
    • Bellone, S.1    Anfossi, S.2    O'Brien, T.J.3
  • 94
    • 0025859335 scopus 로고
    • Use of adoptive transfer of tumor-infiltrating lymphocytes alone or in combination with cisplatin-containing chemotherapy in patients with epithelial ovarian cancer
    • Aoki Y, Takakuwa K, Kodama S et al. Use of adoptive transfer of tumor-infiltrating lymphocytes alone or in combination with cisplatin-containing chemotherapy in patients with epithelial ovarian cancer. Cancer Res. 51(7), 1934-1939 (1991).
    • (1991) Cancer Res. , vol.51 , Issue.7 , pp. 1934-1939
    • Aoki, Y.1    Takakuwa, K.2    Kodama, S.3
  • 95
    • 0029049890 scopus 로고
    • Prolonged disease-free period in patients with advanced epithelial ovarian cancer after adoptive transfer of tumor-infiltrating lymphocytes
    • Fujita K, Ikarashi H, Takakuwa K et al. Prolonged disease-free period in patients with advanced epithelial ovarian cancer after adoptive transfer of tumor-infiltrating lymphocytes. Clin. Cancer Res. 1(5), 501-507 (1995).
    • (1995) Clin. Cancer Res. , vol.1 , Issue.5 , pp. 501-507
    • Fujita, K.1    Ikarashi, H.2    Takakuwa, K.3
  • 96
    • 70350586745 scopus 로고    scopus 로고
    • Autologous MUC1-specific Th1 effector cell immunotherapy induces differential levels of systemic TReg cell subpopulations that result in increased ovarian cancer patient survival
    • Dobrzanski MJ, Rewers-Felkins KA, Quinlin IS et al. Autologous MUC1-specific Th1 effector cell immunotherapy induces differential levels of systemic TReg cell subpopulations that result in increased ovarian cancer patient survival. Clin. Immunol. 133(3), 333-352 (2009).
    • (2009) Clin. Immunol. , vol.133 , Issue.3 , pp. 333-352
    • Dobrzanski, M.J.1    Rewers-Felkins, K.A.2    Quinlin, I.S.3
  • 97
    • 84856834217 scopus 로고    scopus 로고
    • Cytotoxic T-lymphocyte immunotherapy for ovarian cancer: A pilot study
    • Wright SE, Rewers-Felkins KA, Quinlin IS et al. Cytotoxic T-lymphocyte immunotherapy for ovarian cancer: a pilot study. J. Immunother. 35(2), 196-204 (2012).
    • (2012) J. Immunother. , vol.35 , Issue.2 , pp. 196-204
    • Wright, S.E.1    Rewers-Felkins, K.A.2    Quinlin, I.S.3
  • 98
    • 0024834988 scopus 로고
    • Expression of immunoglobulin-T-cell receptor chimeric molecules as functional receptors with antibody-type specificity
    • Gross G, Waks T, Eshhar Z. Expression of immunoglobulin-T-cell receptor chimeric molecules as functional receptors with antibody-type specificity. Proc. Natl Acad. Sci. USA 86(24), 10024-10028 (1989).
    • (1989) Proc. Natl Acad. Sci. USA , vol.86 , Issue.24 , pp. 10024-10028
    • Gross, G.1    Waks, T.2    Eshhar, Z.3
  • 99
    • 77952529498 scopus 로고    scopus 로고
    • Adoptive tcell immunotherapy strategies for the treatment of patients with ovarian cancer
    • Chekmasova AA, Brentjens RJ. Adoptive Tcell immunotherapy strategies for the treatment of patients with ovarian cancer. Discov. Med. 9(44), 62-70 (2010).
    • (2010) Discov. Med. , vol.9 , Issue.44 , pp. 62-70
    • Chekmasova, A.A.1    Brentjens, R.J.2
  • 100
    • 0029134048 scopus 로고
    • In vivo antitumor activity of Tcells redirected with chimeric antibody/T-cell receptor genes
    • Hwu P, Yang JC, Cowherd R etal. In vivo antitumor activity of Tcells redirected with chimeric antibody/T-cell receptor genes. Cancer Res. 55(15), 3369-3373 (1995).
    • (1995) Cancer Res. , vol.55 , Issue.15 , pp. 3369-3373
    • Hwu, P.1    Yang, J.C.2    Cowherd, R.3
  • 101
    • 0034693937 scopus 로고    scopus 로고
    • Expansion and characterization of Tcells transduced with a chimeric receptor against ovarian cancer
    • Parker LL, Do MT, Westwood JA et al. Expansion and characterization of Tcells transduced with a chimeric receptor against ovarian cancer. Hum. Gene Ther. 11(17), 2377-2387 (2000).
    • (2000) Hum. Gene Ther. , vol.11 , Issue.17 , pp. 2377-2387
    • Parker, L.L.1    Do, M.T.2    Westwood, J.A.3
  • 102
    • 30044442768 scopus 로고    scopus 로고
    • Adoptive transfer of Tcells modified with a humanized chimeric receptor gene inhibits growth of Lewis-Y-expressing tumors in mice
    • Westwood JA, Smyth MJ, Teng MW et al. Adoptive transfer of Tcells modified with a humanized chimeric receptor gene inhibits growth of Lewis-Y-expressing tumors in mice. Proc. Natl Acad. Sci. USA 102(52), 19051-19056 (2005).
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , Issue.52 , pp. 19051-19056
    • Westwood, J.A.1    Smyth, M.J.2    Teng, M.W.3
  • 103
    • 67449100831 scopus 로고    scopus 로고
    • The lewis-Y carbohydrate antigen is expressed by many human tumors and can serve as a target for genetically redirected T cells despite the presence of soluble antigen in serum
    • Westwood JA, Murray WK, Trivett M et al. The Lewis-Y carbohydrate antigen is expressed by many human tumors and can serve as a target for genetically redirected T cells despite the presence of soluble antigen in serum. J. Immunother. 32(3), 292-301 (2009).
    • (2009) J. Immunother. , vol.32 , Issue.3 , pp. 292-301
    • Westwood, J.A.1    Murray, W.K.2    Trivett, M.3
  • 104
    • 67349189462 scopus 로고    scopus 로고
    • Adoptive immunotherapy using human peripheral blood lymphocytes transferred with RNA encoding Her-2/neu-specific chimeric immune receptor in ovarian cancer xenograft model
    • Yoon SH, Lee JM, Cho HI et al. Adoptive immunotherapy using human peripheral blood lymphocytes transferred with RNA encoding Her-2/neu-specific chimeric immune receptor in ovarian cancer xenograft model. Cancer Gene Ther. 16(6), 489-497 (2009).
    • (2009) Cancer Gene Ther. , vol.16 , Issue.6 , pp. 489-497
    • Yoon, S.H.1    Lee, J.M.2    Cho, H.I.3
  • 105
    • 84883315080 scopus 로고    scopus 로고
    • Synergistic chemoimmunotherapy of epithelial ovarian cancer using ErbB-retargeted Tcells combined with carboplatin
    • Parente-Pereira AC, Whilding LM, Brewig N et al. Synergistic chemoimmunotherapy of epithelial ovarian cancer using ErbB-retargeted Tcells combined with carboplatin. J. Immunol. 191(5), 2437-2445 (2013).
    • (2013) J. Immunol. , vol.191 , Issue.5 , pp. 2437-2445
    • Parente-Pereira, A.C.1    Whilding, L.M.2    Brewig, N.3
  • 106
    • 77954712252 scopus 로고    scopus 로고
    • Successful eradication of established peritoneal ovarian tumors in SCID-beige mice following adoptive transfer of Tcells genetically targeted to the MUC16 antigen
    • Chekmasova AA, Rao TD, Nikhamin Y et al. Successful eradication of established peritoneal ovarian tumors in SCID-Beige mice following adoptive transfer of Tcells genetically targeted to the MUC16 antigen. Clin. Cancer Res. 16(14), 3594-3606 (2010).
    • (2010) Clin. Cancer Res. , vol.16 , Issue.14 , pp. 3594-3606
    • Chekmasova, A.A.1    Rao, T.D.2    Nikhamin, Y.3
  • 107
    • 36549023384 scopus 로고    scopus 로고
    • WT1-specific T cell receptor gene therapy: Improving TCR function in transduced Tcells
    • Stauss HJ, Thomas S, Cesco-Gaspere M et al. WT1-specific T cell receptor gene therapy: improving TCR function in transduced Tcells. Blood Cells Mol. Dis. 40(1), 113-116 (2008).
    • (2008) Blood Cells Mol. Dis. , vol.40 , Issue.1 , pp. 113-116
    • Stauss, H.J.1    Thomas, S.2    Cesco-Gaspere, M.3
  • 108
    • 84894459822 scopus 로고    scopus 로고
    • Diverse solid tumors expressing a restricted epitope of L1-CAM can be targeted by chimeric antigen receptor redirected T lymphocytes
    • Hong H, Stastny M, Brown C et al. Diverse solid tumors expressing a restricted epitope of L1-CAM can be targeted by chimeric antigen receptor redirected T lymphocytes. J. Immunother. 37(2), 93-104 (2014).
    • (2014) J. Immunother. , vol.37 , Issue.2 , pp. 93-104
    • Hong, H.1    Stastny, M.2    Brown, C.3
  • 109
    • 33750699642 scopus 로고    scopus 로고
    • A Phase I study on adoptive immunotherapy using gene-modified Tcells for ovarian cancer
    • Kershaw MH, Westwood JA, Parker LL et al. A Phase I study on adoptive immunotherapy using gene-modified Tcells for ovarian cancer. Clin. Cancer Res. 12(20 Pt 1), 6106-6115 (2006).
    • (2006) Clin. Cancer Res. , vol.12 , Issue.20 , pp. 6106-6115
    • Kershaw, M.H.1    Westwood, J.A.2    Parker, L.L.3
  • 110
    • 84869236490 scopus 로고    scopus 로고
    • Will T-cell therapy for cancer ever be a standard of care?
    • Brenner MK. Will T-cell therapy for cancer ever be a standard of care? Cancer Gene Ther. 19(12), 818-821 (2012).
    • (2012) Cancer Gene Ther. , vol.19 , Issue.12 , pp. 818-821
    • Brenner, M.K.1
  • 111
    • 84864518399 scopus 로고    scopus 로고
    • A Phase I clinical trial of adoptive transfer of folate receptor-alpha redirected autologous Tcells for recurrent ovarian cancer
    • Kandalaft LE, Powell DJ, Jr., Coukos G. A Phase I clinical trial of adoptive transfer of folate receptor-alpha redirected autologous Tcells for recurrent ovarian cancer. J. Transl. Med. 10, 157 (2012).
    • (2012) J. Transl. Med. , vol.10 , pp. 157
    • Kandalaft, L.E.1    Powell, D.J.2    Coukos, G.3
  • 112
    • 79959914449 scopus 로고    scopus 로고
    • In vivo persistence, tumor localization, and antitumor activity of CAR-engineered T cells is enhanced by costimulatory signaling through CD137 (4-1BB)
    • Song DG, Ye Q, Carpenito C etal. In vivo persistence, tumor localization, and antitumor activity of CAR-engineered T cells is enhanced by costimulatory signaling through CD137 (4-1BB). Cancer Res. 71(13), 4617-4627 (2011).
    • (2011) Cancer Res. , vol.71 , Issue.13 , pp. 4617-4627
    • Song, D.G.1    Ye, Q.2    Carpenito, C.3
  • 113
    • 38449098735 scopus 로고    scopus 로고
    • The role of dendritic cells in cytotoxic immune response regulation in ovarian cancer micro-environment
    • Wertel I, Barczynski B, Kotarski J. The role of dendritic cells in cytotoxic immune response regulation in ovarian cancer micro-environment. Front. Biosci. 13, 2177-2190 (2008).
    • (2008) Front. Biosci. , vol.13 , pp. 2177-2190
    • Wertel, I.1    Barczynski, B.2    Kotarski, J.3
  • 114
    • 84886943568 scopus 로고    scopus 로고
    • Naturally circulating dendritic cells to vaccinate cancer patients
    • Bol KF, Tel J, De Vries IJ, Figdor CG. Naturally circulating dendritic cells to vaccinate cancer patients. Oncoimmunology 2(3), e23431 (2013).
    • (2013) Oncoimmunology , vol.2 , Issue.3 , pp. e23431
    • Bol, K.F.1    Tel, J.2    De Vries, I.J.3    Figdor, C.G.4
  • 115
    • 18644367888 scopus 로고    scopus 로고
    • Local administration of IL-12-transfected dendritic cells induces antitumor immune responses to colon adenocarcinoma in the liver in mice
    • Satoh Y, Esche C, Gambotto A et al. Local administration of IL-12-transfected dendritic cells induces antitumor immune responses to colon adenocarcinoma in the liver in mice. J. Exp. Ther. Oncol. 2(6), 337-349 (2002).
    • (2002) J. Exp. Ther. Oncol. , vol.2 , Issue.6 , pp. 337-349
    • Satoh, Y.1    Esche, C.2    Gambotto, A.3
  • 116
    • 0033566984 scopus 로고    scopus 로고
    • Induction of systemic and therapeutic antitumor immunity using intratumoral injection of dendritic cells genetically modified to express interleukin 12
    • Nishioka Y, Hirao M, Robbins PD, Lotze MT, Tahara H. Induction of systemic and therapeutic antitumor immunity using intratumoral injection of dendritic cells genetically modified to express interleukin 12. Cancer Res. 59(16), 4035-4041 (1999).
    • (1999) Cancer Res. , vol.59 , Issue.16 , pp. 4035-4041
    • Nishioka, Y.1    Hirao, M.2    Robbins, P.D.3    Lotze, M.T.4    Tahara, H.5
  • 117
    • 84886943632 scopus 로고    scopus 로고
    • AAV2/IL-12 gene delivery into dendritic cells (DC) enhances CTL stimulation above other IL-12 applications: Evidence for IL-12 intracrine activity in DC
    • You CX, Shi M, Liu Y, Cao M, Luo R, Hermonat PL. AAV2/IL-12 gene delivery into dendritic cells (DC) enhances CTL stimulation above other IL-12 applications: evidence for IL-12 intracrine activity in DC. Oncoimmunology 1(6), 847-855 (2012).
    • (2012) Oncoimmunology , vol.1 , Issue.6 , pp. 847-855
    • You, C.X.1    Shi, M.2    Liu, Y.3    Cao, M.4    Luo, R.5    Hermonat, P.L.6
  • 118
    • 11144358381 scopus 로고    scopus 로고
    • Intratumoral administration of dendritic cells overexpressing CCL21 generates systemic antitumor responses and confers tumor immunity
    • Yang SC, Hillinger S, Riedl K et al. Intratumoral administration of dendritic cells overexpressing CCL21 generates systemic antitumor responses and confers tumor immunity. Clin. Cancer Res. 10(8), 2891-2901 (2004).
    • (2004) Clin. Cancer Res. , vol.10 , Issue.8 , pp. 2891-2901
    • Yang, S.C.1    Hillinger, S.2    Riedl, K.3
  • 119
    • 33749032429 scopus 로고    scopus 로고
    • Induction of potent antitumor immunity by intratumoral injection of interleukin 23-transduced dendritic cells
    • Hu J, Yuan X, Belladonna ML et al. Induction of potent antitumor immunity by intratumoral injection of interleukin 23-transduced dendritic cells. Cancer Res. 66(17), 8887-8896 (2006).
    • (2006) Cancer Res. , vol.66 , Issue.17 , pp. 8887-8896
    • Hu, J.1    Yuan, X.2    Belladonna, M.L.3
  • 120
    • 0032816863 scopus 로고    scopus 로고
    • Dendritic cells transduced with wild-type p53 gene elicit potent anti-tumour immune responses
    • Ishida T, Chada S, Stipanov M et al. Dendritic cells transduced with wild-type p53 gene elicit potent anti-tumour immune responses. Clin. Exp. Immunol. 117(2), 244-251 (1999).
    • (1999) Clin. Exp. Immunol. , vol.117 , Issue.2 , pp. 244-251
    • Ishida, T.1    Chada, S.2    Stipanov, M.3
  • 121
    • 0033949986 scopus 로고    scopus 로고
    • Generation of T-cell immunity to a murine melanoma using MART-1-engineered dendritic cells
    • Ribas A, Butterfield LH, Hu B et al. Generation of T-cell immunity to a murine melanoma using MART-1-engineered dendritic cells. J. Immunother. 23(1), 59-66 (2000).
    • (2000) J. Immunother. , vol.23 , Issue.1 , pp. 59-66
    • Ribas, A.1    Butterfield, L.H.2    Hu, B.3
  • 122
    • 0034670002 scopus 로고    scopus 로고
    • Induction of antitumor immunity by vaccination of dendritic cells transfected with MUC1 RNA
    • Koido S, Kashiwaba M, Chen D, Gendler S, Kufe D, Gong J. Induction of antitumor immunity by vaccination of dendritic cells transfected with MUC1 RNA. J. Immunol. 165(10), 5713-5719 (2000).
    • (2000) J. Immunol. , vol.165 , Issue.10 , pp. 5713-5719
    • Koido, S.1    Kashiwaba, M.2    Chen, D.3    Gendler, S.4    Kufe, D.5    Gong, J.6
  • 123
    • 0033375998 scopus 로고    scopus 로고
    • Enhanced immune response to the melanoma antigen gp100 using recombinant adenovirus-transduced dendritic cells
    • Wan Y, Emtage P, Zhu Q et al. Enhanced immune response to the melanoma antigen gp100 using recombinant adenovirus-transduced dendritic cells. Cell. Immunol. 198(2), 131-138 (1999).
    • (1999) Cell. Immunol. , vol.198 , Issue.2 , pp. 131-138
    • Wan, Y.1    Emtage, P.2    Zhu, Q.3
  • 124
    • 0029839058 scopus 로고    scopus 로고
    • Dendritic cells pulsed with RNA are potent antigen-presenting cells invitro and invivo
    • Boczkowski D, Nair SK, Snyder D, Gilboa E. Dendritic cells pulsed with RNA are potent antigen-presenting cells invitro and invivo. J. Exp. Med. 184(2), 465-472 (1996).
    • (1996) J. Exp. Med. , vol.184 , Issue.2 , pp. 465-472
    • Boczkowski, D.1    Nair, S.K.2    Snyder, D.3    Gilboa, E.4
  • 125
    • 0030808677 scopus 로고    scopus 로고
    • Bone marrow-generated dendritic cells pulsed with tumor extracts or tumor RNA induce antitumor immunity against central nervous system tumors
    • Ashley DM, Faiola B, Nair S, Hale LP, Bigner DD, Gilboa E. Bone marrow-generated dendritic cells pulsed with tumor extracts or tumor RNA induce antitumor immunity against central nervous system tumors. J. Exp. Med. 186(7), 1177-1182 (1997).
    • (1997) J. Exp. Med. , vol.186 , Issue.7 , pp. 1177-1182
    • Ashley, D.M.1    Faiola, B.2    Nair, S.3    Hale, L.P.4    Bigner, D.D.5    Gilboa, E.6
  • 126
    • 0034652624 scopus 로고    scopus 로고
    • Induction of tumor immunity and cytotoxic T lymphocyte responses using dendritic cells transfected with messenger RNA amplified from tumor cells
    • Boczkowski D, Nair SK, Nam JH, Lyerly HK, Gilboa E. Induction of tumor immunity and cytotoxic T lymphocyte responses using dendritic cells transfected with messenger RNA amplified from tumor cells. Cancer Res. 60(4), 1028-1034 (2000).
    • (2000) Cancer Res. , vol.60 , Issue.4 , pp. 1028-1034
    • Boczkowski, D.1    Nair, S.K.2    Nam, J.H.3    Lyerly, H.K.4    Gilboa, E.5
  • 127
    • 12144286596 scopus 로고    scopus 로고
    • In vivo targeting of antigens to maturing dendritic cells via the DEC-205 receptor improves Tcell vaccination
    • Bonifaz LC, Bonnyay DP, Charalambous A etal. In vivo targeting of antigens to maturing dendritic cells via the DEC-205 receptor improves Tcell vaccination. J. Exp. Med. 199(6), 815-824 (2004).
    • (2004) J. Exp. Med. , vol.199 , Issue.6 , pp. 815-824
    • Bonifaz, L.C.1    Bonnyay, D.P.2    Charalambous, A.3
  • 128
    • 0037122011 scopus 로고    scopus 로고
    • Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ Tcell tolerance
    • Bonifaz L, Bonnyay D, Mahnke K, Rivera M, Nussenzweig MC, Steinman RM. Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ Tcell tolerance. J. Exp. Med. 196(12), 1627-1638 (2002).
    • (2002) J. Exp. Med. , vol.196 , Issue.12 , pp. 1627-1638
    • Bonifaz, L.1    Bonnyay, D.2    Mahnke, K.3    Rivera, M.4    Nussenzweig, M.C.5    Steinman, R.M.6
  • 129
    • 23744481998 scopus 로고    scopus 로고
    • Effective induction of naive and recall T-cell responses by targeting antigen to human dendritic cells via a humanized anti-DC-SIGN antibody
    • Tacken PJ, De Vries IJ, Gijzen K et al. Effective induction of naive and recall T-cell responses by targeting antigen to human dendritic cells via a humanized anti-DC-SIGN antibody. Blood 106(4), 1278-1285 (2005).
    • (2005) Blood , vol.106 , Issue.4 , pp. 1278-1285
    • Tacken, P.J.1    De Vries, I.J.2    Gijzen, K.3
  • 130
    • 84890254287 scopus 로고    scopus 로고
    • Trial watch: Dendritic cell-based interventions for cancer therapy
    • Vacchelli E, Vitale I, Eggermont A et al. Trial watch: dendritic cell-based interventions for cancer therapy. Oncoimmunology 2(10), e25771 (2013).
    • (2013) Oncoimmunology , vol.2 , Issue.10 , pp. e25771
    • Vacchelli, E.1    Vitale, I.2    Eggermont, A.3
  • 132
    • 33745210324 scopus 로고    scopus 로고
    • A biophysical approach to the optimisation of dendritic-tumour cell electrofusion
    • Sukhorukov VL, Reuss R, Endter JM et al. A biophysical approach to the optimisation of dendritic-tumour cell electrofusion. Biochem. Biophys. Res. Commun. 346(3), 829-839 (2006).
    • (2006) Biochem. Biophys. Res. Commun. , vol.346 , Issue.3 , pp. 829-839
    • Sukhorukov, V.L.1    Reuss, R.2    Endter, J.M.3
  • 133
    • 84862495613 scopus 로고    scopus 로고
    • PhaseI/II randomized trial of dendritic cell vaccination with or without cyclophosphamide for consolidation therapy of advanced ovarian cancer in first or second remission
    • Chu CS, Boyer J, Schullery DS et al. PhaseI/II randomized trial of dendritic cell vaccination with or without cyclophosphamide for consolidation therapy of advanced ovarian cancer in first or second remission. Cancer Immunol. Immunother. 61(5), 629-641 (2012).
    • (2012) Cancer Immunol. Immunother. , vol.61 , Issue.5 , pp. 629-641
    • Chu, C.S.1    Boyer, J.2    Schullery, D.S.3
  • 134
    • 32944475905 scopus 로고    scopus 로고
    • Mannan-MUC1-pulsed dendritic cell immunotherapy: A Phase I trial in patients with adenocarcinoma
    • Loveland BE, Zhao A, White S et al. Mannan-MUC1-pulsed dendritic cell immunotherapy: a Phase I trial in patients with adenocarcinoma. Clin. Cancer Res. 12(3 Pt 1), 869-877 (2006).
    • (2006) Clin. Cancer Res. , vol.12 , Issue.3 , pp. 869-877
    • Loveland, B.E.1    Zhao, A.2    White, S.3
  • 135
    • 84858766182 scopus 로고    scopus 로고
    • The blockade of immune checkpoints in cancer immunotherapy
    • Pardoll DM. The blockade of immune checkpoints in cancer immunotherapy. Nature reviews. Cancer 12(4), 252-264 (2012).
    • (2012) Nature Reviews. Cancer , vol.12 , Issue.4 , pp. 252-264
    • Pardoll, D.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.