AAV2/IL-12 gene delivery into dendritic cells (DC) enhances CTL stimulation above other IL-12 applications: Evidence for IL-12 intracrine activity in DC

OncoImmunology

Volumn 1, Issue 6, 2012, Pages 847-855

  You, Chang Xuan ^a,b   Shi, Min ^a,b   Liu, Yong ^a   Cao, Maohua ^a   Luo, Rongcheng ^b   Hermonat, Paul L ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

Adeno associated virus; Cancer; Cytotoxic T lymphocytes; Dendritic cell; Gene therapy; Interleukin 12; Intracrine

Indexed keywords

B7 ANTIGEN; CARCINOEMBRYONIC ANTIGEN; CD4 ANTIGEN; CD40 ANTIGEN; CD69 ANTIGEN; CD8 ANTIGEN; CD83 ANTIGEN; CD86 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 2 RECEPTOR ALPHA;

ANTIGEN EXPRESSION; ARTICLE; AUTOCRINE GENE DELIVERY; CELL KILLING; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; GENE TARGETING; HUMAN; HUMAN CELL; IL 12 GENE; INTERMETHOD COMPARISON; INTRACRINE GENE DELIVERY; LYMPHOCYTE PROLIFERATION; MALE; NUCLEOTIDE SEQUENCE; PARACRINE SIGNALING; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; VIRAL GENE DELIVERY SYSTEM;

EID: 84886943632     PISSN: 21624011     EISSN: 2162402X     Source Type: Journal    
DOI: 10.4161/onci.20504     Document Type: Article

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