Evaluation of AaDOP2 receptor antagonists reveals antidepressants and antipsychotics as novel lead molecules for control of the yellow fever mosquito, Aedes aegypti

Journal of Pharmacology and Experimental Therapeutics

Volumn 352, Issue 1, 2015, Pages 53-60

  Conley, Jason M ^a   Meyer, Jason M ^b   Nuss, Andrew B ^b   Doyle, Trevor B ^a   Savinov, Sergey N ^b   Hill, Catherine A ^b   Watts, Val J ^a  

^a PURDUE UNIVERSITY   (United States)

^b PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; AMITRIPTYLINE; AMOXAPINE; AMPEROZIDE; ANTIDEPRESSANT AGENT; ASENAPINE; ATOMOXETINE; BENZATROPINE; BUTACLAMOL; CHLORPROMAZINE; CHLORPROTHIXENE; CLOMIPRAMINE; D1 LIKE DOPAMINE RECEPTOR ANTAGONIST; DESIPRAMINE; DOXEPIN; FLUOXETINE; FLUPENTIXOL; FLUVOXAMINE; HALIDE; IMIPRAMINE; INSECTICIDE; METITEPINE; NEUROLEPTIC AGENT; NORCLOMIPRAMINE; NORTRIPTYLINE; PROTRIPTYLINE; RECEPTOR BLOCKING AGENT; TRAZODONE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VENLAFAXINE; DOPAMINE RECEPTOR; DOPAMINE RECEPTOR BLOCKING AGENT; INSECT PROTEIN; MOLECULAR LIBRARY;

AEDES AEGYPTI; ARTICLE; CELL VIABILITY; CLINICAL EVALUATION; CONFORMATION; FEMALE; HUMAN; HUMAN CELL; IC50; IN VITRO STUDY; IN VIVO STUDY; LARVA; LD 50; LIPOPHILICITY; MORTALITY; MOSQUITO; NONHUMAN; STRUCTURE ACTIVITY RELATION; TOXICITY TESTING; TREND STUDY; AEDES; ANIMAL; ANTAGONISTS AND INHIBITORS; HEK293 CELL LINE; HIGH THROUGHPUT SCREENING; METABOLISM; MOLECULAR LIBRARY; PHYSIOLOGY; PRECLINICAL STUDY; PROCEDURES; TRANSMISSION; YELLOW FEVER;

AEDES; ANIMALS; ANTIDEPRESSIVE AGENTS; ANTIPSYCHOTIC AGENTS; DOPAMINE ANTAGONISTS; DRUG EVALUATION, PRECLINICAL; FEMALE; HEK293 CELLS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; INSECT PROTEINS; LARVA; MOSQUITO CONTROL; RECEPTORS, DOPAMINE; SMALL MOLECULE LIBRARIES; YELLOW FEVER;

EID: 84919779649     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.114.219717     Document Type: Article

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