Dopamine is a regulator of arousal in the fruit fly

Journal of Neuroscience

Volumn 25, Issue 32, 2005, Pages 7377-7384

  Kume, Kazuhiko ^a,b   Kume, Shoen ^a   Park, Sang Ki ^c,d   Hirsh, Jay ^c   Jackson, F Rob ^b  

^a KUMAMOTO UNIVERSITY   (Japan)

^b TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF VIRGINIA   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Arousal; Dopamine; Dopamine transporter; Drosophila; Rest; Sleep

Indexed keywords

DOPAMINE;

ANIMAL EXPERIMENT; AROUSAL; ARTICLE; CIRCADIAN RHYTHM; CONTROLLED STUDY; DOPAMINERGIC SYSTEM; DROSOPHILA; DROSOPHILA DOPAMINE TRANSPORTER GENE; FEMALE; FUMIN GENE; GENE; GENE MAPPING; GENE MUTATION; GENETIC MODEL; HOMEOSTASIS; LIFESPAN; MALE; MAMMAL; MECHANICAL STIMULATION; MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SLEEP; SLEEP WAKING CYCLE; WILD TYPE;

ALLELES; ANIMALS; AROUSAL; DIFFERENTIAL THRESHOLD; DOPAMINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DROSOPHILA; DROSOPHILA PROTEINS; FEMALE; FERTILITY; LONGEVITY; MALE; MOTOR ACTIVITY; MUTATION; SIGNAL TRANSDUCTION; SLEEP DEPRIVATION;

EID: 23744439861     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2048-05.2005     Document Type: Article

References (50)

1. Abarca C, Albrecht U, Spanagel R (2002) Cocaine sensitization and reward are under the influence of circadian genes and rhythm. Proc Natl Acad Sci USA 99:9026-9030.
2. Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, et al. (2000) The genome sequence of Drosophila melanogaster. Science 287:2185-2195.
3. Andretic R, Shaw PJ (2005) Essentials of sleep recordings in Drosophila: moving beyond sleep time. Methods Enzymol 393:759-772.
4. Andretic R, Chaney S, Hirsh J (1999) Circadian genes are required for cocaine sensitization in Drosophila. Science 285:1066-1068.
5. Andretic R, van Swinderen B, Greenspan RJ (2005) Dopaminergic modulation of arousal in Drosophila. Curr Biol 15:1165-1175.
6. Arnulf I, Konofal E, Merino-Andreu M, Houeto JL, Mesnage V, Welter ML, Lacomblez L, Golmard JL, Derenne JP, Agid Y (2002) Parkinson's disease and sleepiness: an integral part of PD. Neurology 58:1019-1024.
7. Bainton RJ, Tsai LT, Singh CM, Moore MS, Neckameyer WS, Heberlein U (2000) Dopamine modulates acute responses to cocaine, nicotine and ethanol in Drosophila. Curr Biol 10:187-194.
8. Banerjee S, Lee J, Venkatesh K, Wu CF, Hasan G (2004) Loss of flight and associated neuronal rhythmicity in inositol 1,4,5-trisphosphate receptor mutants of Drosophila. J Neurosci 24:7869-7878.
9. Borbely AA (1982) A two process model of sleep regulation. Hum Neurobiol 1:195-204.
10. Boutrel B, Koob GF (2004) What keeps us awake: the neuropharmacology of stimulants and wakefulness-promoting medications. Sleep 27:1181-1194.
11. Cirelli C, Bushey D, Hill S, Huber R, Kreber R, Ganetzky B, Tononi G (2005) Reduced sleep in Drosophila Shaker mutants. Nat Neurosci 434:1087-1092.
12. Clarenbach P (2000) Parkinson's disease and sleep. J Neurol 247 [Suppl 4]:20-23.
13. Cooper RL, Neckameyer WS (1999) Dopaminergic modulation of motor neuron activity and neuromuscular function in Drosophila melanogaster. Comp Biochem Physiol B Biochem Mol Biol 122:199-210.
14. Cyran SA, Buchsbaum AM, Reddy KL, Lin MC, Glossop NR, Hardin PE, Young MW, Storti RV, Blau J (2003) vrille, Pdp1, and dClock form a second feedback loop in the Drosophila circadian clock. Cell 112:329-341.
15. Dasari S, Cooper RL (2004) Modulation of sensory-CNS-motor circuits by serotonin, octopamine, and dopamine in semi-intact Drosophila larva. Neurosci Res 48:221-227.
16. Gainetdinov RR, Wetsel WC, Jones SR, Levin ED, Jaber M, Caron MG (1999) Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity. Science 283:397-401.
17. George R, Lease K, Burnette J, Hirsh J (2005) A "bottom- counting" video system for measuring cocaine-induced behaviors in Drosophila. Methods Enzymol 393:841-851.
18. Giros B, Jaber M, Jones SR, Wightman RM, Caron MG (1996) Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter. Nature 379:606-612.
19. Helfrich-Forster C (1998) Robust circadian rhythmicity of Drosophila melanogaster requires the presence of lateral neurons: a brain-behavioral study of disconnected mutants. J Comp Physiol [A] 182:435-453.
20. Hendricks JC, Finn SM, Panckeri KA, Chavkin J, Williams JA, Sehgal A, Pack AI (2000) Rest in Drosophila is a sleep-like state, Neuron 25:129-138.
21. Hendricks JC, Lu S, Kume K, Yin JC, Yang Z, Sehgal A (2003a) Gender dimorphism in the role of cycle (BMAL1) in rest, rest regulation, and longevity in Drosophila melanogaster. J Biol Rhythms 18:12-25.
22. Hendricks JC, Kirk D, Panckeri K, Miller MS, Pack AI (2003b) Modafinil maintains waking in the fruit fly Drosophila melanogaster. Sleep 26:139-146.
23. Ho KS, Sehgal A (2005) Drosophila melanogaster. an insect model for fundamental studies of sleep. Methods Enzymol 393:772-793.
24. Isaac SO, Berridge CW (2003) Wake-promoting actions of dopamine D1 and D2 receptor stimulation. J Pharmacol Exp Ther 307:386-394.
25. Jones SR, Gainetdinov RR, Jaber M, Giros B, Wightman RM, Caron MG (1998) Profound neuronal plasticity in response to inactivation of the dopamine transporter. Proc Natl Acad Sci USA 95:4029-4034.
26. Jones SR, Gainetdinov RR, Hu XT, Cooper DC, Wightman RM, White FJ, Caron MG (1999) Loss of autoreceptor functions in mice lacking the dopamine transporter. Nat Neurosci 2:649-655.
27. Kaminker JS, Bergman CM, Kronmiller B, Carlson J, Svirskas R, Patel S, Frise E, Wheeler DA, Lewis SE, Rubin GM, Ashburner M, Celniker SE (2002) The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective. Genome Biol 3:0084.1-0084.20.
28. Li H, Chaney S, Forte M, Hirsh I (2000) Ectopic G-protein expression in dopamine and serotonin neurons blocks cocaine sensitization in Drosophila melanogaster. Curr Biol 10:211-214.
29. Lima SQ, Miesenbock G (2005) Remote control of behavior through genetically targeted photostimulation of neurons. Cell 121:141-152.
30. Marder E, Bucher D (2001) Central pattern generators and the control of rhythmic movements. Curr Biol 11:R986-R996.
31. McClung C, Hirsh J (1998) Stereotypic behavioral responses to free-base cocaine and the development of behavioral sensitization in Drosophila melanogaster. Curr Biol 8:109-112.
32. Morales J, Hiesinger PR, Schroeder AJ, Kume K, Verstreken P, Jackson FR, Nelson DL, Hassan BA (2002) Drosophila fragile X protein, DFXR, regulates neuronal morphology and function in the brain. Neuron 34:961-972.
33. Newby LM, White L, DiBartolomeis SM, Walker BJ, Dowse HB, Ringo JM, Khuda N, Jackson FR (1991) Mutational analysis of the Drosophila miniature-dusky (m-dy) locus: effects on cell size and circadian rhythms. Genetics 128:571-582.
34. Nishino S, Mao J, Sampathkumaran R, Shelton J (1998) Increased dopaminergic transmission mediates the wake-promoting effects of CNS stimulants. Sleep Res Online 1:49-61.
35. Nishino S, Fujiki N, Ripley B, Sakurai E, Kato M, Watanabe T, Mignot E, Yanai K (2001) Deer eased brain histamine content in hypocretin/orexin receptor-2 mutated narcoleptic dogs. Neurosci Lett 313:125-128.
36. Okura M, Riehl J, Mignot E, Nishino S (2000) Sulpiride, a D2/D3 blocker, reduces cataplexy but not REM sleep in canine narcolepsy. Neuropsychopharmacology 23:528-538.
37. Panda S, Hogenesch JB, Kay SA (2002) Circadian rhythms from flies to human. Nature 417:329-335.
38. Pendleton RG, Rasheed A, Sardina T, Tully T, Hillman R (2002) Effects of tyrosine hydroxylase mutants on locomotor activity in Drosophila: a study in functional genomics. Behav Genet 32:89-94.
39. Porzgen P, Park SK, Hirsh J, Sonders MS, Amara SG (2001) The antidepressant-sensitive dopamine transporter in Drosophila melanogaster. a primordial carrier for catecholamines. Mol Pharmacol 59:83-95.
40. Reppert SM, Weaver DR (2002) Coordination of circadian timing in mammals. Nature 418:935-941.
41. Saraswati S, Fox LE, Soll DR, Wu CF (2004) Tyramine and octopamine have opposite effects on the locomotion of Drosophila larvae. J Neurobiol 58:425-441.
42. Shaw PJ, Cirelli C, Greenspan RJ, Tononi G (2000) Correlates of sleep and waking in Drosophila melanogaster. Science 287:1834-1837.
43. Shaw PJ, Tononi G, Greenspan RJ, Robinson DF (2002) Stress response genes protect against lethal effects of sleep deprivation in Drosophila. Nature 417:287-291.
44. Siegel JM (2004) The neurotransmitters of sleep. J Clin Psychiatry 65 [Suppl 16]:4-7.
45. Spielewoy C, Roubert C, Hamon M, Nosten-Bertrand M, Betancur C, Giros B (2000) Behavioural disturbances associated with hyperdopaminergia in dopamine-transporter knockout mice. Behav Pharmacol 11:279-290.
46. Tamura T, Chiang AS, Ito N, Liu HP, Horiuchi J, Tully T, Saitoe M (2003) Aging specifically impairs amnesiac-dependent memory in Drosophila. Neuron 40:1003-1011.
47. Tobler I (1983) Effect of forced locomotion on the rest-activity cycle of the cockroach. Behav Brain Res 8:351-360.
48. Vaslet CA, O'Connell P, Izquierdo M, Rosbash M (1980) Isolation and mapping of a cloned ribosomal protein gene of Drosophila melanogaster. Nature 285:674-676.
49. Wisor JP, Nishino S, Sora I, Uhl GH, Mignot E, Edgar DM (2001) Dopaminergic role in stimulant-induced wakefulness. J Neurosci 21:1787-1794.
50. Yellman C, Tao H, He B, Hirsh J (1997) Conserved and sexually dimorphic behavioral responses to biogenic amines in decapitated Drosophila. Proc Natl Acad Sci USA 94:4131-4136.