Diffusion-weighted MR imaging of the pancreas: Current status and recommendations

Radiology

Volumn 274, Issue 1, 2015, Pages 45-63

  Barral, Matthias ^a   Taouli, Bachir ^b   Guiu, Boris ^c   Koh, Doh Mu ^d   Luciani, Alain ^e   Manfredi, Riccardo ^f   Vilgrain, Valérie ^g   Hoeffel, Christine ^h   Kanematsu, Masayuki ⁱ   Soyer, Philippe ^a,j  

^a HÔPITAL LARIBOISIÈRE   (France)

^b MOUNT SINAI MEDICAL CENTER   (United States)

^c HÔPITAL DU BOCAGE   (France)

^d ROYAL MARSDEN HOSPITAL   (United Kingdom)

^e HENRI MONDOR HOSPITAL   (France)

^f UNIVERSITY OF VERONA   (Italy)

^g BEAUJON HOSPITAL   (France)

^h SERVICE DE DERMATOLOGIE   (France)

ⁱ GIFU UNIVERSITY HOSPITAL   (Japan)

^j UNIVERSITÉ PARIS DESCARTES   (France)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE PANCREATITIS; ADJUVANT CHEMORADIOTHERAPY; APPARENT DIFFUSION COEFFICIENT; AUTOIMMUNE PANCREATITIS; BIEXPONENTIAL MODEL; BIOLOGICAL MODEL; CHRONIC PANCREATITIS; CYSTADENOMA; DIFFUSION COEFFICIENT; DIFFUSION WEIGHTED IMAGING; DUCTAL ADENOCARCINOMA; HUMAN; IMAGE ACQUISITION; IMAGE PROCESSING; IMAGE QUALITY; IMAGING AND DISPLAY; INTRADUCTAL PAPILLARY MUCINOUS TUMOR; LIMIT OF QUANTITATION; MAGNETIC FIELD STRENGTH; MATHEMATICAL ANALYSIS; MONOEXPONENTIAL MODEL; PANCREAS ADENOCARCINOMA; PANCREAS CANCER; PANCREAS EXAMINATION; PANCREAS ISLET CELL TUMOR; PANCREAS PSEUDOCYST; PARENCHYMA; PHYSICAL PHENOMENA; REPRODUCIBILITY; REVIEW; SENSITIVITY AND SPECIFICITY; SOLID TUMOR; TREATMENT RESPONSE; COMPUTER ASSISTED DIAGNOSIS; DIAGNOSTIC USE; IMAGE ENHANCEMENT; PANCREATIC DISEASES; PROCEDURES;

CONTRAST MEDIUM;

CONTRAST MEDIA; DIFFUSION MAGNETIC RESONANCE IMAGING; HUMANS; IMAGE ENHANCEMENT; IMAGE INTERPRETATION, COMPUTER-ASSISTED; PANCREATIC DISEASES;

EID: 84919767018     PISSN: 00338419     EISSN: 15271315     Source Type: Journal    
DOI: 10.1148/radiol.14130778     Document Type: Review

References (121)

1. Akisik MF, Aisen AM, Sandrasegaran K, et al. Assessment of chronic pancreatitis: utility of diffusion-weighted MR imaging with se-cretin enhancement. Radiology 2009; 250(1): 103-109.
2. Lee SS, Byun JH, Park BJ, et al. Quantitative analysis of diffusion-weighted magnetic resonance imaging of the pancreas: usefulness in characterizing solid pancreatic masses. J Magn Reson Imaging 2008; 28(4): 928-936.
3. Akisik MF, Sandrasegaran K, Jennings SG, et al. Diagnosis of chronic pancreatitis by using apparent diffusion coefficient measurements at 3.0-T MR following secretin stimulation. Radiology 2009; 252(2): 418-425.
4. Guiu B, Cercueil JP. Liver diffusion-weighted MR imaging: the tower of Babel? Eur Radiol 2011; 21(3): 463-467.
5. Qayyum A. Diffusion-weighted imaging in the abdomen and pelvis: concepts and applications. RadioGraphics 2009; 29(6): 1797-1810.
6. Koh DM, Collins DJ, Orton MR. Intravoxel incoherent motion in body diffusion-weighted MRI: reality and challenges. AJR Am J Roentgenol 2011; 196(6): 1351-1361.
7. Ichikawa T, Haradome H, Hachiya J, Nitatori T, Araki T. Diffusion-weighted MR imaging with single-shot echo-planar imaging in the upper abdomen: preliminary clinical experience in 61 patients. Abdom Imaging 1999; 24(5): 456-461.
8. Pruessmann KP, Weiger M, Scheidegger MB, Boesiger P. SENSE: sensitivity encoding for fast MRI. Magn Reson Med 1999; 42(5): 952-962.
9. Kanematsu M, Goshima S, Watanabe H, et al. Diffusion/perfusion MR imaging of the liver: practice, challenges, and future. Magn Reson Med Sci 2012; 11(3): 151-161.
10. Okada Y, Ohtomo K, Kiryu S, Sasaki Y. Breath-hold T2-weighted MRI of hepatic tumors: value of echo planar imaging with diffusion-sensitizing gradient. J Comput Assist Tomogr 1998; 22(3): 364-371.
11. Rosenkrantz AB, Oei M, Babb JS, Niver BE, Taouli B. Diffusion-weighted imaging of the abdomen at 3.0 Tesla: image quality and apparent diffusion coefficient reproducibil-ity compared with 1.5 Tesla. J Magn Reson Imaging 2011; 33(1): 128-135.
12. Le Bihan D, Breton E, Lallemand D, Aubin ML, Vignaud J, Laval-Jeantet M. Separation of diffusion and perfusion in intravoxel incoherent motion MR imaging. Radiology 1988; 168(2): 497-505.
13. Einstein A. Investigations on the theory of Brownian movements. 2nd ed. New York, NY: Dover, 1956.
14. Le Bihan D, Breton E, Lallemand D, Grenier P, Cabanis E, Laval-Jeantet M. MR imaging of intravoxel incoherent motions: application to diffusion and perfusion in neurologic disorders. Radiology 1986; 161(2): 401-407.
15. Stejskal EO Use of spin-echoes in a pulse magnetic-field gradient to study anisotropic, restricted diffusion and flow. J Chem Phys 1965; 43(10): 3597-3603.
16. Padhani AR, Liu G, Koh DM, et al. Diffusion-weighted magnetic resonance imaging as a cancer biomarker: consensus and recommendations. Neoplasia 2009; 11(2): 102-125.
17. Bittencourt LK, Matos C, Coutinho AC Jr Diffusion-weighted magnetic resonance imaging in the upper abdomen: technical issues and clinical applications. Magn Reson Imaging Clin N Am 2011; 19(1): 111-131.
18. Klauss M, Lemke A, Grünberg K, et al. In-travoxel incoherent motion MRI for the differentiation between mass forming chronic pancreatitis and pancreatic carcinoma. Invest Radiol 2011; 46(1): 57-63.
19. Le Bihan D. Looking into the functional architecture of the brain with diffusion MRI. Nat Rev Neurosci 2003; 4(6): 469-480.
20. Zhang JL, Sigmund EE, Chandarana H, et al. Variability of renal apparent diffusion coefficients: limitations of the monoexpo-nential model for diffusion quantification. Radiology 2010; 254(3): 783-792.
21. Lemke A, Laun FB, Simon D, Stieltjes B, Schad LR. An in vivo verification of the intravoxel incoherent motion effect in diffusion-weighted imaging of the abdomen. Magn Reson Med 2010; 64(6): 1580-1585.
22. Andreou A, Koh DM, Collins DJ, et al. Measurement reproducibility of perfusion fraction and pseudodiffusion coefficient derived by intravoxel incoherent motion diffusion-weighted MR imaging in normal liver and metastases. Eur Radiol 2013; 23(2): 428-434.
23. Dyvorne HA, Galea N, Nevers T, et al. Diffusion-weighted imaging of the liver with multiple b values: effect of diffusion gradient polarity and breathing acquisition on image quality and intravoxel incoherent motion parameters - a pilot study. Radiology 2013; 266(3): 920-929.
24. Wang CL, Chea YW, Boll DT, et al. Effect of gadolinium chelate contrast agents on diffusion weighted MR imaging of the liver, spleen, pancreas and kidney at 3 T. Eur J Radiol 2011; 80(2): e1-e7.
25. Gulani V, Willatt JM, Blaimer M, Hussain HK, Duerk JL, Griswold MA. Effect of contrast media on single-shot echo planar imaging: implications for abdominal diffusion imaging. J Magn Reson Imaging 2009; 30(5): 1203-1208.
26. Liu K, Peng W, Zhou Z. The effect of gadolinium chelate contrast agent on diffusion-weighted imaging of pancreatic ductal adeno-carcinoma. Acta Radiol 2013; 54(4): 364-368.
27. Pledger T, Shah SN, Taouli B. Diffusion-weighted magnetic resonance imaging of the liver. Eradimaging Web site. http://www.eradimaging.com/site/article.cfm?ID=772. Published February 11, 2011. Accessed August 28, 2014.
28. Collins DJ, Blackledge M. Techniques and optimization. In: Koh DM, Thoeny HC, eds. Diffusion-weighted MR imaging: applications in the body. New York, NY: Springer, 2009; 19-32.
29. Low RN Diffusion-weighted MR imaging for whole body metastatic disease and lymph-adenopathy. Magn Reson Imaging Clin N Am 2009; 17(2): 245-261.
30. Yoshikawa T, Kawamitsu H, Mitchell DG, et al. ADC measurement of abdominal organs and lesions using parallel imaging technique. AJR Am J Roentgenol 2006; 187(6): 1521-1530.
31. Soyer P, Lagadec M, Sirol M, et al. Free-breathing diffusion-weighted single-shot echo-planar MR imaging using parallel imaging (GRAPPA 2) and high b value for the detection of primary rectal adenocarcinoma. Cancer Imaging 2010; 10: 32-39.
32. Taouli B, Martin AJ, Qayyum A, et al. Parallel imaging and diffusion tensor imaging for diffusion-weighted MRI of the liver: preliminary experience in healthy volunteers. AJR Am J Roentgenol 2004; 183(3): 677-680.
33. Griswold MA, Jakob PM, Heidemann RM, et al. Generalized autocalibrating partially parallel acquisitions (GRAPPA). Magn Reson Med 2002; 47(6): 1202-1210.
34. Thierfelder KM, Sommer WH, Dietrich O, et al. Parallel-transmit-accelerated spatially-selective excitation MRI for reduced-fov diffusion-weighted-imaging of the pancreas. Eur J Radiol 2014; 83(10): 1709-1714.
35. Riffel P, Michaely HJ, Morelli JN, et al. Zoomed EPI-DWI of the pancreas using two-dimensional spatially-selective radio-frequency excitation pulses. PLoS One 2014; 9: e89468.
36. Ma C, Li YJ, Pan CS, et al. High resolution diffusion weighted magnetic resonance imaging of the pancreas using reduced field of view single-shot echo-planar imaging at 3 T. Magn Reson Imaging 2014; 32: 125-131.
37. Kandpal H, Sharma R, Madhusudhan KS, Kapoor KS. Respiratory-triggered versus breath-hold diffusion-weighted MRI of liver lesions: comparison of image quality and apparent diffusion coefficient values. AJR Am J Roentgenol 2009; 192(4): 915-922.
38. Yao XZ, Yun H, Zeng MS, et al. Evaluation of ADC measurements among solid pancreatic masses by respiratory-triggered diffusion-weighted MR imaging with inversion-recovery fat-suppression technique at 3.0T. Magn Reson Imaging 2013; 31(4): 524-528.
39. Taouli B, Sandberg A, Stemmer A, et al. Diffusion-weighted imaging of the liver: comparison of navigator triggered and breath-hold acquisitions. J Magn Reson Imaging 2009; 30(3): 561-568.
40. Saremi F, Jalili M, Sefidbakht S, et al. Diffusion-weighted imaging of the abdomen at 3 T: image quality comparison with 1.5-T magnet using 3 different imaging sequences. J Comput Assist Tomogr 2011; 35(3): 317-325.
41. Takahara T, Imai Y, Yamashita T, Yasuda S, Nasu S, Van Cauteren M. Diffusion weighted whole body imaging with background body signal suppression (DWIBS): technical improvement using free breathing, STIR and high resolution 3D display. Radiat Med 2004; 22(4): 275-282.
42. Kim S Y, Lee SS, Byun JH, et al. Malignant hepatic tumors: short-term reproducibility of apparent diffusion coefficients with breath-hold and respiratory-triggered diffusion-weighted MR imaging. Radiology 2010; 255(3): 815-823.
43. Nasu K, Kuroki Y, Fujii H, Minami M. Hepatic pseudo-anisotropy: a specific artifact in hepatic diffusion-weighted images obtained with respiratory triggering. MAGMA 2007; 20(4): 205-211.
44. Braithwaite AC, Dale BM, Boll DT, Merkle EM. Short- and midterm reproducibility of apparent diffusion coefficient measurements at 3.0-T diffusion-weighted imaging of the abdomen. Radiology 2009; 250(2): 459-465.
45. Barral M, Soyer P, Ben Hassen W, et al. Diffusion-weighted MR imaging of the normal pancreas: reproducibility and variations of apparent diffusion coefficient measurement at 1.5- and 3.0-Tesla. Diagn Interv Imaging 2013; 94(4): 418-427.
46. Dale BM, Braithwaite AC, Boll DT, Merkle EM. Field strength and diffusion encoding technique affect the apparent diffusion co-efficient measurements in diffusion-weighted imaging of the abdomen. Invest Radiol 2010; 45(2): 104-108.
47. Donati OF, Chong D, Nanz D, et al. Diffusion-weighted MR imaging of upper abdominal organs: field strength and intervendor variability of apparent diffusion coefficients. Radiology 2014; 270: 454-463.
48. Taniguchi T, Kobayashi H, Nishikawa K, et al. Diffusion-weighted magnetic resonance imaging in autoimmune pancreatitis. Jpn J Radiol 2009; 27(3): 138-142.
49. Wiggermann P, Grützmann R, Weissenböck A, Kamusella P, Dittert DD, Stroszczynski C. Apparent diffusion coefficient measurements of the pancreas, pancreas carcinoma, and mass-forming focal pancreatitis. Acta Radiol 2012; 53(2): 135-139.
50. Wang Y, Chen ZE, Yaghmai V, et al. Diffusion-weighted MR imaging in pancreatic endocrine tumors correlated with histopatho-logic characteristics. J Magn Reson Imaging 2011; 33(5): 1071-1079.
51. Caramella C, Dromain C, De Baere T, et al. Endocrine pancreatic tumours: which are the most useful MRI sequences? Eur Radiol 2010; 20(11): 2618-2627.
52. Thomas S, Kayhan A, Lakadamyali H, Oto A. Diffusion MRI of acute pancreatitis and comparison with normal individuals using ADC values. Emerg Radiol 2012; 19(1): 5-9.
53. Ginde AA, Foianini A, Renner DM, Valley M, Camargo CA Jr Availability and quality of computed tomography and magnetic resonance imaging equipment in U.S. emergency departments. Acad Emerg Med 2008; 15(8): 780-783.
54. Kamisawa T, Takuma K, Anjiki H, et al. Differentiation of autoimmune pancreatitis from pancreatic cancer by diffusion-weighted MRI. Am J Gastroenterol 2010; 105(8): 1870-1875.
55. Takakura K, Sumiyama K, Munakata K, et al. Clinical usefulness of diffusion-weighted MR imaging for detection of pancreatic cancer: comparison with enhanced multidetector-row CT. Abdom Imaging 2011; 36(4): 457-462.
56. Bilgili Y, Unal B. Effect of region of interest on interobserver variance in apparent diffusion coefficient measures. AJNR Am J Neuroradiol 2004; 25(1): 108-111.
57. Brenner R, Metens T, Bali M, Demetter P, Matos C. Pancreatic neuroendocrine tumor: added value of fusion of T2-weighted imaging and high b-value diffusion-weighted imaging for tumor detection. Eur J Radiol 2012; 81(5): e746-e749.
58. Bakir B, Salmaslioʇlu A, Poyanli A, Rozanes I, Acunas B. Diffusion weighted MR imaging of pancreatic islet cell tumors. Eur J Radiol 2010; 74(1): 214-220.
59. Kartalis N, Lindholm TL, Aspelin P, Permert J, Albiin N. Diffusion-weighted magnetic resonance imaging of pancreas tumours. Eur Radiol 2009; 19(8): 1981-1990.
60. Zech CJ, Herrmann KA, Dietrich O, Horger W, Reiser MF, Schoenberg SO. Black-blood diffusion-weighted EPI acquisition of the liver with parallel imaging: comparison with a standard T2-weighted sequence for detection of focal liver lesions. Invest Radiol 2008; 43(4): 261-266.
61. Coenegrachts K, Delanote J, Ter Beek L, et al. Improved focal liver lesion detection: comparison of single-shot diffusion-weighted echoplanar and single-shot T2 weighted turbo spin echo techniques. Br J Radiol 2007; 80(955): 524-531.
62. Braithwaite AC, Dale BM, Boll DT, Merkle EM. Short- and midterm reproducibility of apparent diffusion coefficient measurements at 3.0-T diffusion-weighted imaging of the abdomen. Radiology 2009; 250(2): 459-465.
63. Do RK, Chandarana H, Felker E, et al. Diagnosis of liver fibrosis and cirrhosis with diffusion-weighted imaging: value of normalized apparent diffusion coefficient using the spleen as reference organ. AJR Am J Roentgenol 2010; 195(3): 671-676.
64. Barral M, Sebbag-Sfez D, Hoeffel C, et al. Characterization of focal pancreatic lesions using normalized apparent diffusion coeffi-cient at 1.5-Tesla: preliminary experience. Diagn Interv Imaging 2013; 94(6): 619-627.
65. Soyer P, Spelle L, Pelage JP, et al. Cystic fibrosis in adolescents and adults: fatty replacement of the pancreas-CT evaluation and functional correlation. Radiology 1999; 210(3): 611-615.
66. Lugo-Olivieri CH, Soyer PA, Fishman EK. Cystic fibrosis: spectrum of thoracic and abdominal CT findings in the adult patient. Clin Imaging 1998; 22(5): 346-354.
67. Soyer P, Kanematsu M, Taouli B, et al. ADC normalization: a promising research track for diffusion-weighted MR imaging of the abdomen. Diagn Interv Imaging 2013; 94(6): 571-573.
68. Boraschi P, Donati F, Gigoni R, Salemi S, Bartolozzi C, Falaschi F. Diffusion-weighted MRI in the characterization of cystic pancreatic lesions: usefulness of ADC values. Magn Reson Imaging 2010; 28(10): 1447-1455.
69. Wang Y, Chen ZE, Nikolaidis P, et al. Diffusion-weighted magnetic resonance imaging of pancreatic adenocarcinomas: association with histopathology and tumor grade. J Magn Reson Imaging 2011; 33(1): 136-142.
70. Fattahi R, Balci NC, Perman WH, et al. Pancreatic diffusion-weighted imaging (DWI): comparison between mass-forming focal pancreatitis (FP), pancreatic cancer (PC), and normal pancreas. J Magn Reson Imaging 2009; 29(2): 350-356.
71. Matsuki M, Inada Y, Nakai G, et al. Diffusion-weighed MR imaging of pancreatic carcinoma. Abdom Imaging 2007; 32(4): 481-483.
72. Lemke A, Laun FB, Klauss M, et al. Differentiation of pancreas carcinoma from healthy pancreatic tissue using multiple b-values: comparison of apparent diffusion coefficient and intravoxel incoherent motion derived parameters. Invest Radiol 2009; 44(12): 769-775.
73. Erturk SM, Ichikawa T, Motosugi U, Sou H, Araki T. Diffusion-weighted MR imaging in the evaluation of pancreatic exocrine function before and after secretin stimulation. Am J Gastroenterol 2006; 101(1): 133-136.
74. Balci NC, Momtahen AJ, Akduman EI, Al-kaade S, Bilgin M, Burton FR. Diffusion-weighted MRI of the pancreas: correlation with secretin endoscopic pancreatic function test (ePFT). Acad Radiol 2008; 15(10): 1264-1268.
75. Re TJ, Lemke A, Klauss M, et al. Enhancing pancreatic adenocarcinoma delineation in diffusion derived intravoxel incoherent motion f-maps through automatic vessel and duct segmentation. Magn Reson Med 2011; 66(5): 1327-1332.
76. Momtahen AJ, Balci NC, Alkaade S, Akduman EI, Burton FR. Focal pancreatitis mimicking pancreatic mass: magnetic resonance imaging (MRI)/magnetic resonance cholangiopancreatography (MRCP) findings including diffusion-weighted MRI. Acta Radiol 2008; 49(5): 490-497.
77. Fukukura Y, Takumi K, Kamimura K, et al. Pancreatic adenocarcinoma: variability of diffusion-weighted MR imaging findings. Radiology 2012; 263(3): 732-740.
78. Muraoka N, Uematsu H, Kimura H, et al. Apparent diffusion coefficient in pancreatic cancer: characterization and histopatho-logical correlations. J Magn Reson Imaging 2008; 27(6): 1302-1308.
79. Muhi A, Ichikawa T, Motosugi U, et al. Mass-forming autoimmune pancreatitis and pancreatic carcinoma: differential diagnosis on the basis of computed tomography and magnetic resonance cholangiopancreatography, and diffusion-weighted imaging findings. J Magn Reson Imaging 2012; 35(4): 827-836.
80. Takeuchi M, Matsuzaki K, Kubo H, Nishitani H. High-b-value diffusion-weighted magnetic resonance imaging of pancreatic cancer and mass-forming chronic pancreatitis: preliminary results. Acta Radiol 2008; 49(4): 383-386.
81. Rosenkrantz AB, Matza BW, Sabach A, Hajdu CH, Hindman N. Pancreatic cancer: lack of association between apparent diffusion coefficient values and adverse pathological features. Clin Radiol 2013; 68(4): e191-e197.
82. Schoennagel BP, Habermann CR, Roesch M, et al. Diffusion-weighted imaging of the healthy pancreas: apparent diffusion coeffi-cient values of the normal head, body, and tail calculated from different sets of b-val-ues. J Magn Reson Imaging 2011; 34(4): 861-865.
83. Kiliçkesmez O, Yirik G, Bayramoʇlu S, Cimilli T, Aydin S. Non-breath-hold high b-value diffusion-weighted MRI with parallel imaging technique: apparent diffusion coefficient determination in normal abdominal organs. Diagn Interv Radiol 2008; 14(2): 83-87.
84. Sasaki M, Yamada K, Watanabe Y, et al. Variability in absolute apparent diffusion coefficient values across different platforms may be substantial: a multivendor, multi-institutional comparison study. Radiology 2008; 249(2): 624-630.
85. Herrmann J, Schoennagel BP, Roesch M, et al. Diffusion-weighted imaging of the healthy pancreas: ADC values are age and gender dependent. J Magn Reson Imaging 2013; 37(4): 886-891.
86. Yoshikawa T, Ohno Y, Kawamitsu H, et al. Abdominal apparent diffusion coefficient measurements: effect of diffusion-weighted image quality and usefulness of anisotropic images. Magn Reson Imaging 2008; 26(10): 1415-1420.
87. Wathle GK, Tjora E, Ersland L, et al. Assessment of exocrine pancreatic function by secretin-stimulated magnetic resonance cholangiopancreaticography and diffusion-weighted imaging in healthy controls. J Magn Reson Imaging 2014; 39: 448-454.
88. Hellund JC, Storaas T, Gjesdal KI, Klow NE, Geitung JT. Magnetic resonance-assisted imaging of slow flow in the pancreatic and common bile duct in healthy volunteers. Acta Radiol 2007; 48(9): 943-947.
89. Bockman DE, Büchler M, Beger HG. Ultrastructure of human acute pancreatitis. Int J Pancreatol 1986; 1(2): 141-153.
90. Shinya S, Sasaki T, Nakagawa Y, Guiquing Z, Yamamoto F, Yamashita Y. The efficacy of diffusion-weighted imaging for the detection and evaluation of acute pancreatitis. Hepatogastroenterology 2009; 56(94-95): 1407-1410.
91. Islim F, Salik AE, Bayramoglu S, Guven K, Alis H, Turhan AN. Non-invasive detection of infection in acute pancreatic and acute necrotic collections with diffusion-weighted magnetic resonance imaging: preliminary findings. Abdom Imaging 2014: 39: 3: 472-481.
92. Takuma K, Kamisawa T, Gopalakrishna R, et al. Strategy to differentiate autoimmune pancreatitis from pancreas cancer. World J Gastroenterol 2012; 18(10): 1015-1020.
93. Hur BY, Lee JM, Lee JE, et al. Magnetic resonance imaging findings of the mass-forming type of autoimmune pancreatitis: comparison with pancreatic adenocarcinoma. J Magn Reson Imaging 2012; 36(1): 188-197.
94. Oki H, Hayashida Y, Oki H, et al. DWI findings of autoimmune pancreatitis: comparison between symptomatic and asymptomatic patients. J Magn Reson Imaging 2013; DOI: 10.1002/jmri.24508.
95. Yusuf TE, Bhutani MS. Differentiating pancreatic cancer from pseudotumorous chronic pancreatitis. Curr Gastroenterol Rep 2002; 4(2): 135-139.
96. Fusari M, Maurea S, Imbriaco M, et al. Comparison between multislice CT and MR imaging in the diagnostic evaluation of patients with pancreatic masses. Radiol Med (Torino) 2010; 115(3): 453-466.
97. Kim JK, Altun E, Elias J Jr, Pamuklar E, Rivero H, Semelka RC. Focal pancreatic mass: distinction of pancreatic cancer from chronic pancreatitis using gadolinium-enhanced 3D-gradient-echo MRI. J Magn Reson Imaging 2007; 26(2): 313-322.
98. Ichikawa T, Erturk SM, Motosugi U, et al. High-b value diffusion-weighted MRI for detecting pancreatic adenocarcinoma: preliminary results. AJR Am J Roentgenol 2007; 188(2): 409-414.
99. Wagner M, Doblas S, Daire JL, et al. Diffusion-weighted MR imaging for the regional characterization of liver tumors. Radiology 2012; 264(2): 464-472.
100. Huang WC, Sheng J, Chen SY, Lu JP. Differentiation between pancreatic carcinoma and mass-forming chronic pancreatitis: usefulness of high b value diffusion-weighted imaging. J Dig Dis 2011; 12(5): 401-408.
101. Jang KM, Kim SH, Kim YK, et al. Imaging features of small (≥ 3 cm) pancreatic solid tumors on gadoxetic-acid-enhanced MR imaging and diffusion-weighted imaging: an initial experience. Magn Reson Imaging 2012; 30(7): 916-925.
102. Hayano K, Miura F, Amano H, et al. Correlation of apparent diffusion coefficient measured by diffusion-weighted MRI and clinicopathologic features in pancreatic cancer patients. J Hepatobiliary Pancreat Sci 2013; 20(2): 243-248.
103. Concia M, Sprinkart AM, Penner AH, et al. Diffusion-weighted magnetic resonance imaging of the pancreas: diagnostic benefit from an intravoxel incoherent motion model-based 3 b-value analysis. Invest Radiol 2014; 49: 93-100.
104. Klauss M, Gaida MM, Lemke A, et al. Fibrosis and pancreatic lesions: counterintuitive behavior of the diffusion imaging-derived structural diffusion coefficient d. Invest Radiol 2013; 48(3): 129-133.
105. Park MJ, Kim YK, Choi SY, Rhim H, Lee WJ, Choi D. Preoperative detection of small pancreatic adenocarcinoma: value of adding diffusion-weighted imaging to conventional MR imaging for improving confidence level. Radiology 2014: 273(2): 433-443.
106. Schmid-Tannwald C, Schmid-Tannwald CM, Morelli JN, et al, Rist C. Comparison of abdominal MRI with diffusion-weighted imaging to 68Ga-DOTATATE PET/CT in detection of neuroendocrine tumors of the pancreas. Eur J Nucl Med Mol Imaging 2013; 40: 897-907.
107. Kang KM, Lee JM, Yoon JH, Kiefer B, Han JK, Choi BI. Intravoxel incoherent motion diffusion-weighted MR imaging for characterization of focal pancreatic lesions. Radiology 2014; 270: 444-453.
108. Hwang EJ, Lee JM, Yoon JH, et al. Intravoxel incoherent motion diffusion-weighted imaging of pancreatic neuroendocrine tumors: prediction of the histologic grade using pure diffusion coefficient and tumor size. Invest Radiol 2014; 49: 396-402.
109. d'Assignies G, Fina P, Bruno O, et al. High sensitivity of diffusion-weighted MR imaging for the detection of liver metastases from neuroendocrine tumors: comparison with T2-weighted and dynamic gadolinium-enhanced MR imaging. Radiology 2013; 268(2): 390-399.
110. Barral M, Soyer P, Dohan A, et al. Magnetic resonance imaging of cystic pancreatic lesions in adults: an update in current diagnostic features and management. Abdom Imaging 2014; 39: 48-65.
111. Mottola JC, Sahni VA, Erturk SM, Swanson R, Banks PA, Mortele KJ. Diffusion-weighted MRI of focal cystic pancreatic lesions at 3.0-Tesla: preliminary results. Abdom Imaging 2012; 37(1): 110-117.
112. Inan N, Arslan A, Akansel G, Anik Y, Demirci A. Diffusion-weighted imaging in the differential diagnosis of cystic lesions of the pancreas. AJR Am J Roentgenol 2008; 191(4): 1115-1121.
113. Yamashita Y, Namimoto T, Mitsuzaki K, et al. Mucin-producing tumor of the pancreas: diagnostic value of diffusion-weighted echo-planar MR imaging. Radiology 1998; 208(3): 605-609.
114. Fatima Z, Ichikawa T, Motosugi U, et al. Magnetic resonance diffusion-weighted imaging in the characterization of pancreatic mucinous cystic lesions. Clin Radiol 2011; 66(2): 108-111.
115. Irie H, Honda H, Kuroiwa T, et al. Measurement of the apparent diffusion coef-ficient in intraductal mucin-producing tumor of the pancreas by diffusion-weighted echo-planar MR imaging. Abdom Imaging 2002; 27(1): 82-87.
116. Sandrasegaran K, Akisik FM, Patel AA, et al. Diffusion-weighted imaging in characterization of cystic pancreatic lesions. Clin Radiol 2011; 66(9): 808-814.
117. Schraibman V, Goldman SM, Ardengh JC, et al. New trends in diffusion-weighted magnetic resonance imaging as a tool in differentiation of serous cystadenoma and mucinous cystic tumor: a prospective study. Pancreatology 2011; 11(1): 43-51.
118. Kang KM, Lee JM, Shin CI, et al. Added value of diffusion-weighted imaging to MR cholangiopancreatography with unenhanced mr imaging for predicting malignancy or in-vasiveness of intraductal papillary mucinous neoplasm of the pancreas. J Magn Reson Imaging 2013; 38: 555-563.
119. Guerrache Y, Soyer P, Dohan A, et al. Solid-pseudopapillary tumor of the pancreas: MR imaging findings in 21 patients. Clin Imaging 2014; 38: 475-482.
120. Jang KM, Kim SH, Lee SJ, Park MJ, Lee MH, Choi D. Differentiation of an intra-pancreatic accessory spleen from a small (,3-cm) solid pancreatic tumor: value of diffusion-weighted MR imaging. Radiology 2013; 266(1): 159-167.
121. Lemke A, Stieltjes B, Schad LR, Laun FB. Toward an optimal distribution of b values for intravoxel incoherent motion imaging. Magn Reson Imaging 2011; 29(6): 766-776.