MS-275 inhibits aroclor 1254-induced SH-SY5Y neuronal cell toxicity by preventing the formation of the HDAC3/REST complex on the synapsin-1 promoter

Journal of Pharmacology and Experimental Therapeutics

Volumn 352, Issue 2, 2015, Pages 236-243

  Formisano, Luigi ^a   Guida, Natascia ^b   Laudati, Guisy ^b   Mascolo, Luigi ^b   Di Renzo, Gianfranco ^b   Canzoniero, Lorella M T ^a,b  

^a UNIVERSITY OF SANNIO   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

3 [4 [3 (3 FLUOROPHENYL) 3 OXO 1 PROPENYL] 1 METHYL 1H PYRROL 2 YL]ACRYLOHYDROXAMIC ACID; AROCLOR 1254; ENTINOSTAT; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 2; HISTONE DEACETYLASE 3; HISTONE H3; MESSENGER RNA; POLYCHLORINATED BIPHENYL; RE 1 SILENCING TRANSCRIPTION FACTOR; SYNAPSIN I; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; BENZAMIDE DERIVATIVE; HISTONE; HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR; PROTEIN BINDING; PYRIDINE DERIVATIVE; RE1-SILENCING TRANSCRIPTION FACTOR; REPRESSOR PROTEIN; SMALL INTERFERING RNA; SYNAPSIN;

ARTICLE; BRAIN CELL; COMPLEX FORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; GENE EXPRESSION; HISTONE ACETYLATION; HUMAN; HUMAN CELL; NERVE CELL NECROSIS; NEUROBLASTOMA CELL; NEUROPROTECTION; PROMOTER REGION; PROTEIN PROTEIN INTERACTION; ACETYLATION; ANTAGONISTS AND INHIBITORS; CELL DEATH; CHROMATIN IMMUNOPRECIPITATION; DRUG EFFECTS; GENE SILENCING; GENETICS; METABOLISM; NERVE CELL; REAL TIME POLYMERASE CHAIN REACTION; TUMOR CELL LINE; WESTERN BLOTTING;

ACETYLATION; BENZAMIDES; BLOTTING, WESTERN; CELL DEATH; CELL LINE, TUMOR; CHLORODIPHENYL (54% CHLORINE); CHROMATIN IMMUNOPRECIPITATION; GENE KNOCKDOWN TECHNIQUES; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; HISTONES; HUMANS; NEURONS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PYRIDINES; REAL-TIME POLYMERASE CHAIN REACTION; REPRESSOR PROTEINS; RNA, SMALL INTERFERING; SYNAPSINS;

EID: 84919766523     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.114.219345     Document Type: Article

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