Subchronic polychlorinated biphenyl (aroclor 1254) exposure produces oxidative damage and neuronal death of ventral midbrain dopaminergic systems

Toxicological Sciences

Volumn 125, Issue 2, 2012, Pages 496-508

  Lee, Donna W ^a   Notter, Sarah A ^a   Thiruchelvam, Mona ^b   Dever, Daniel P ^a   Fitzpatrick, Richard ^c   Kostyniak, Paul J ^c   Cory slechta, Deborah A ^a   Opanashuk, Lisa A ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^b RUTGERS UNIVERSITY   (United States)

^c UNIVERSITY AT BUFFALO   (United States)

Author keywords

Environment; Iron; Neurodegeneration; Organochlorines; Oxidative stress; Parkinson's disease

Indexed keywords

AROCLOR 1254; DOPAMINE; FERRITIN; IRON; POLYCHLORINATED BIPHENYL; SUPEROXIDE DISMUTASE; TRANSFERRIN RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; DOPAMINERGIC SYSTEM; FOOD INTAKE; LIPID OXIDATION; LOCOMOTION; MALE; MOUSE; NERVE CELL NECROSIS; NONHUMAN; OXIDATIVE STRESS; PARKINSON DISEASE; PROTEIN MODIFICATION; SUBSTANTIA NIGRA; VENTRAL TEGMENTUM;

MURINAE;

EID: 84862919805     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfr313     Document Type: Article

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