Suppression of Adult Neurogenesis Increases the Acute Effects of Kainic Acid

Experimental Neurology

Volumn 264, Issue , 2015, Pages 135-149

  Iyengar, Sloka S ^a   LaFrancois, John J ^a   Friedman, Daniel ^b   Drew, Liam J ^c   Denny, Christine A ^d   Burghardt, Nesha S ^e   Wu, Melody V ^d   Hsieh, Jenny ^f   Hen, René ^d,f,g   Scharfman, Helen E ^a,b  

^a NATHAN S KLINE INSTITUTE FOR PSYCHIATRIC RESEARCH   (United States)

^b NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d Department of Psychiatry Columbia University College of Physicians and Surgeons ^*  (United States)

^e CITY UNIVERSITY OF NEW YORK   (United States)

^f UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^g NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

Author keywords

Convulsive seizures; Dentate gyrus; Electroencephalography (EEG); Epilepsy; Hippocampus; Inhibition; Interictal spikes (IIS); Subgranular zone (SGZ)

Indexed keywords

ETHOSUXIMIDE; KAINIC ACID; PLACEBO; AMINO ACID RECEPTOR STIMULATING AGENT; ANTICONVULSIVE AGENT; DOUBLECORTIN PROTEIN; GANCICLOVIR; GLIAL FIBRILLARY ACIDIC PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; NEUROPEPTIDE; THYMIDINE KINASE; VALGANCICLOVIR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; BRAIN REGION; COMPETITIVE INHIBITION; CONTROLLED STUDY; DENTATE GYRUS; DISEASE PREDISPOSITION; DISEASE SEVERITY; ELECTROENCEPHALOGRAPHY; FOCAL EPILEPSY; FOREBRAIN; GENE DELETION; GLIA CELL; MALE; MORTALITY; MOUSE; MOUSE MODEL; NERVE CELL DIFFERENTIATION; NERVE CELL INHIBITION; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NEUROTOXICITY; NONHUMAN; OLFACTORY BULB; PHARMACOGENETICS; SEIZURE; SEIZURE SUSCEPTIBILITY; SPIKE WAVE; TOXICITY TESTING; X IRRADIATION; ANALOGS AND DERIVATIVES; ANIMAL; C57BL MOUSE; CHEMICALLY INDUCED; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECTS; GENETICS; HIPPOCAMPUS; METABOLISM; PATHOLOGY; SEIZURES; X RAY;

ANIMALS; ANTICONVULSANTS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROENCEPHALOGRAPHY; ETHOSUXIMIDE; EXCITATORY AMINO ACID AGONISTS; GANCICLOVIR; GLIAL FIBRILLARY ACIDIC PROTEIN; HIPPOCAMPUS; KAINIC ACID; MALE; MICE; MICE, INBRED C57BL; MICROTUBULE-ASSOCIATED PROTEINS; NEURAL STEM CELLS; NEUROGENESIS; NEUROPEPTIDES; SEIZURES; THYMIDINE KINASE; X-RAYS;

EID: 84919752792     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2014.11.009     Document Type: Article

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