Hypothalamic PGC-1α protects against high-fat diet exposure by regulating ERα

Cell Reports

Volumn 9, Issue 2, 2014, Pages 633-645

  Morselli, Eugenia ^a,b   Fuente Martin, Esther ^c   Finan, Brian ^c   Kim, Min ^a   Frank, Aaron ^a   Garcia Caceres, Cristina ^c   Navas, Carlos Rodriguez ^a   Gordillo, Ruth ^a   Neinast, Michael ^a   Kalainayakan, Sarada P ^a   Li, Dan L ^a   Gao, Yuanqing ^c   Yi, Chun Xia ^c   Hahner, Lisa ^a   Palmer, Biff F ^a   Tschöp, Matthias H ^c   Clegg, Deborah J ^a,d  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^d CEDARS SINAI MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CERAMIDE; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; GLUCOSE; GLUCOSYLCERAMIDE; INTERLEUKIN 10; INTERLEUKIN 1BETA; MESSENGER RNA; PALMITIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; SPHINGOLIPID; SPHINGOMYELIN; TUMOR NECROSIS FACTOR ALPHA; PPARGC1A PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARCUATE NUCLEUS; ARTICLE; ASTROCYTE; ASTROCYTOSIS; BRAIN LEVEL; BRAIN NERVE CELL; CENTRAL NERVOUS SYSTEM DISEASE; CENTRAL NERVOUS SYSTEM INFLAMMATION; CONTROLLED STUDY; DISEASE ASSOCIATION; DOWN REGULATION; ENCEPHALITIS; FATTY ACID METABOLISM; FEMALE; GENE SILENCING; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; HYPOTHALAMIC INFLAMMATION; HYPOTHALAMUS; IMPAIRED GLUCOSE TOLERANCE; IN VITRO STUDY; IN VIVO STUDY; LIPID ANALYSIS; LIPID DIET; LONG TERM EXPOSURE; MALE; METABOLIC REGULATION; MOLECULAR DYNAMICS; MOUSE; MYOCARDIAL DISEASE; NEUROPROTECTION; NONHUMAN; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REGULATORY MECHANISM; RISK REDUCTION; RNA INTERFERENCE; SEX DIFFERENCE; WEIGHT GAIN; ADVERSE EFFECTS; ANIMAL; C57BL MOUSE; CELL LINE; CYTOLOGY; DRUG EFFECTS; GENETICS; HEART VENTRICLE FUNCTION; INFLAMMATION; METABOLISM; NERVE CELL;

MUS;

ANIMALS; ASTROCYTES; CELL LINE; DIET, HIGH-FAT; ESTROGEN RECEPTOR ALPHA; FEMALE; HYPOTHALAMUS; INFLAMMATION; MALE; MICE; MICE, INBRED C57BL; NEURONS; PALMITIC ACID; SEX FACTORS; SPHINGOLIPIDS; TRANSCRIPTION FACTORS; VENTRICULAR DYSFUNCTION;

EID: 84919674550     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2014.09.025     Document Type: Article

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