Evolution of the multi-domain structures of virulence genes in the human malaria parasite, Plasmodium falciparum

PLoS Computational Biology

Volumn 8, Issue 4, 2012, Pages

  Buckee, Caroline O ^a   Recker, Mario ^b  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGENS; ARCHITECTURE; ECONOMIC AND SOCIAL EFFECTS; ENCODING (SYMBOLS); GENE EXPRESSION; VALUE ENGINEERING;

GENE FAMILIES; HOST TISSUES; HUMAN MALARIA PARASITE; MULTIDOMAIN STRUCTURE; PLASMODIUM FALCIPARUM; RED BLOOD CELL; SEQUENCE CONSERVATION; SURFACE ANTIGEN; VIRULENCE FACTORS; VIRULENCE GENE;

DISEASES;

ERYTHROCYTE MEMBRANE PROTEIN 1; ERYTHROCYTE MEMBRANE PROTEIN 1, PLASMODIUM FALCIPARUM; PROTOZOAL PROTEIN; VIRULENCE FACTOR;

ARTICLE; BETWEEN HOST IMMUNE SELECTION; BINDING SITE; CONTROLLED STUDY; CROSS REACTION; CYSTEINE RICH INTERDOMAIN REGION; DUFFY BINDING LIKE DOMAIN; GENE; GENE FREQUENCY; GENE LENGTH; GENE SEQUENCE; GENE STRUCTURE; GENETIC ASSOCIATION; GENETIC CONSERVATION; GENETIC PARAMETERS; GENETIC VARIABILITY; GENOME ANALYSIS; GENOTYPE; HOST PARASITE INTERACTION; MALARIA FALCIPARUM; MATHEMATICAL MODEL; MOLECULAR EVOLUTION; NONHUMAN; PARASITE VIRULENCE; PHENOTYPE; PLASMODIUM FALCIPARUM; PROTEIN DOMAIN; PROTEIN STRUCTURE; UPSTREAM PROMOTER REGION A GENE; UPSTREAM PROMOTER REGION B GENE; UPSTREAM PROMOTER REGION C GENE; VAR GENE; WITHIN HOST FITNESS; AMINO ACID SEQUENCE; CHEMISTRY; GENETICS; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PROTEIN TERTIARY STRUCTURE;

PLASMODIUM FALCIPARUM;

AMINO ACID SEQUENCE; BASE SEQUENCE; EVOLUTION, MOLECULAR; GENETIC VARIATION; MOLECULAR SEQUENCE DATA; PLASMODIUM FALCIPARUM; PROTEIN STRUCTURE, TERTIARY; PROTOZOAN PROTEINS; VIRULENCE FACTORS;

EID: 84861139508     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1002451     Document Type: Article

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