Maf1 Is a Novel Target of PTEN and PI3K Signaling That Negatively Regulates Oncogenesis and Lipid Metabolism

PLoS Genetics

Volumn 10, Issue 12, 2014, Pages

  Palian, Beth M ^a   Rohira, Aarti D ^a,c   Johnson, Sandra A S ^a,c   He, Lina ^b   Zheng, Ni ^b   Dubeau, Louis ^a   Stiles, Bangyan L ^b   Johnson, Deborah L ^a,c  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA DIRECTED RNA POLYMERASE III; FATTY ACID SYNTHASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR MAF1; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; FORKHEAD TRANSCRIPTION FACTOR; FOXO1 PROTEIN, HUMAN; FOXO1 PROTEIN, MOUSE; MAF1 PROTEIN, HUMAN; MAF1 PROTEIN, MOUSE; PTEN PROTEIN, HUMAN; PTEN PROTEIN, MOUSE; REPRESSOR PROTEIN;

ANCHORAGE INDEPENDENT GROWTH; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CANCER INHIBITION; CARCINOGENESIS; ENZYME ACTIVATION; GENE CONTROL; HUMAN; HUMAN TISSUE; LIPID METABOLISM; LIPID STORAGE; LIPOGENESIS; MOUSE; MOUSE MODEL; NEOPLASM; NONHUMAN; PROMOTER REGION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; ANIMAL; C57BL MOUSE; CHROMATIN IMMUNOPRECIPITATION; COMPLICATION; GENETICS; HEPG2 CELL LINE; IMMUNOHISTOCHEMISTRY; MALE; METABOLISM; OBESITY; TUMOR CELL LINE;

MUS;

ANIMALS; CARCINOGENESIS; CELL LINE, TUMOR; CHROMATIN IMMUNOPRECIPITATION; FORKHEAD TRANSCRIPTION FACTORS; HEP G2 CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; LIPID METABOLISM; MALE; MICE; MICE, INBRED C57BL; NEOPLASMS; OBESITY; PHOSPHATIDYLINOSITOL 3-KINASES; PROMOTER REGIONS, GENETIC; PTEN PHOSPHOHYDROLASE; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION;

EID: 84919625964     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004789     Document Type: Article

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