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Volumn 1333, Issue 1, 2014, Pages 33-42

Sequencing the head and neck cancer genome: Implications for therapy

Author keywords

Head and neck cancer; Mutation; Next generation sequencing; NOTCH1

Indexed keywords

HUMAN PAPILLOMAVIRUS; NICOTIANA TABACUM;

EID: 84919617522     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/nyas.12599     Document Type: Article
Times cited : (40)

References (48)
  • 2
    • 79952232216 scopus 로고    scopus 로고
    • Global cancer statistics
    • Jemal, A. et al. 2011. Global cancer statistics. Cancer J. Clin. 61: 69-90.
    • (2011) Cancer J. Clin. , vol.61 , pp. 69-90
    • Jemal, A.1
  • 3
    • 51649093834 scopus 로고    scopus 로고
    • Recent advances in head and neck cancer
    • Haddad, R.I. & D.M. Shin . 2008. Recent advances in head and neck cancer. New Engl. J. Med. 359: 1143-1154.
    • (2008) New Engl. J. Med , vol.359 , pp. 1143-1154
    • Haddad, R.I.1    Shin, D.M.2
  • 4
    • 66149109235 scopus 로고    scopus 로고
    • Human papillomavirus and head and neck squamous cell carcinoma: recent evidence and clinical implications
    • Hennessey, P.T., W.H. Westra & J.A. Califano . 2009. Human papillomavirus and head and neck squamous cell carcinoma: recent evidence and clinical implications. J. Dental Res. 88: 300-306.
    • (2009) J. Dental Res. , vol.88 , pp. 300-306
    • Hennessey, P.T.1    Westra, W.H.2    Califano, J.A.3
  • 5
    • 80052177544 scopus 로고    scopus 로고
    • Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1
    • Agrawal, N. et al. 2011. Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1. Science 333: 1154-1157.
    • (2011) Science , vol.333 , pp. 1154-1157
    • Agrawal, N.1
  • 6
    • 80052158097 scopus 로고    scopus 로고
    • The mutational landscape of head and neck squamous cell carcinoma
    • Stransky, N. et al. 2011. The mutational landscape of head and neck squamous cell carcinoma. Science 333: 1157-1160.
    • (2011) Science , vol.333 , pp. 1157-1160
    • Stransky, N.1
  • 7
    • 84893429306 scopus 로고    scopus 로고
    • Genetic events in head and neck squamous cell carcinoma revealed
    • Nelson, N.J. 2013. Genetic events in head and neck squamous cell carcinoma revealed. J. Natl. Cancer Inst. 105: 1766-1768.
    • (2013) J. Natl. Cancer Inst , vol.105 , pp. 1766-1768
    • Nelson, N.J.1
  • 8
    • 84880281635 scopus 로고    scopus 로고
    • Integrative genomic characterization of oral squamous cell carcinoma identifies frequent somatic drivers
    • Pickering, C.R. et al. 2013. Integrative genomic characterization of oral squamous cell carcinoma identifies frequent somatic drivers. Cancer Discov. 3: 770-781.
    • (2013) Cancer Discov , vol.3 , pp. 770-781
    • Pickering, C.R.1
  • 9
    • 84899880744 scopus 로고    scopus 로고
    • Novel insight into mutational landscape of head and neck squamous cell carcinoma
    • Gaykalova, D.A. et al. 2014. Novel insight into mutational landscape of head and neck squamous cell carcinoma. PloS One 9: e93102.
    • (2014) PloS One , vol.9 , pp. e93102
    • Gaykalova, D.A.1
  • 10
    • 70449339945 scopus 로고    scopus 로고
    • Microdroplet-based PCR enrichment for large-scale targeted sequencing
    • Tewhey, R. et al. 2009. Microdroplet-based PCR enrichment for large-scale targeted sequencing. Nat. Biotechnol. 27: 1025-1031.
    • (2009) Nat. Biotechnol , vol.27 , pp. 1025-1031
    • Tewhey, R.1
  • 11
    • 84904394239 scopus 로고    scopus 로고
    • Squamous cell carcinoma of the oral tongue in young non-smokers is genomically similar to tumors in older smokers
    • Pickering, C.R. et al. 2014. Squamous cell carcinoma of the oral tongue in young non-smokers is genomically similar to tumors in older smokers. Clin. Cancer Res. 20: 3842-3848
    • (2014) Clin. Cancer Res. , vol.20 , pp. 3842-3848
    • Pickering, C.R.1
  • 12
    • 84944031585 scopus 로고    scopus 로고
    • Clinical, genomic and metagenomic characterization of oral tongue squamous cell carcinoma in patients who do not smoke
    • Li, R. et al. 2014. Clinical, genomic and metagenomic characterization of oral tongue squamous cell carcinoma in patients who do not smoke. Head & Neck. doi: 10.1002/hed.23807.
    • (2014) Head & Neck
    • Li, R.1
  • 13
    • 80052565730 scopus 로고    scopus 로고
    • Human papillomavirus and rising oropharyngeal cancer incidence in the United States
    • Chaturvedi, A.K. et al. 2011. Human papillomavirus and rising oropharyngeal cancer incidence in the United States. J. Clin. Oncol. 29: 4294-4301.
    • (2011) J. Clin. Oncol. , vol.29 , pp. 4294-4301
    • Chaturvedi, A.K.1
  • 15
    • 84906790609 scopus 로고    scopus 로고
    • TP53 mutation and human papilloma virus status of oral squamous cell carcinomas in young adult patients
    • Braakhuis, B. et al. 2013. TP53 mutation and human papilloma virus status of oral squamous cell carcinomas in young adult patients. Oral Dis 20: 602-608.
    • (2013) Oral Dis , vol.20 , pp. 602-608
    • Braakhuis, B.1
  • 16
    • 84879334206 scopus 로고    scopus 로고
    • High frequency of activating PIK3CA mutations in human papillomavirus-positive oropharyngeal cancer
    • Nichols, A.C. et al. 2013. High frequency of activating PIK3CA mutations in human papillomavirus-positive oropharyngeal cancer. JAMA Otolaryngol-Head Neck Surg. 139: 617-622.
    • (2013) JAMA Otolaryngol-Head Neck Surg , vol.139 , pp. 617-622
    • Nichols, A.C.1
  • 17
    • 84899741071 scopus 로고    scopus 로고
    • Reverse-phase protein array profiling of oropharyngeal cancer and significance of PIK3CA mutations in HPV-associated head and neck cancer
    • Sewell, A. et al. 2014. Reverse-phase protein array profiling of oropharyngeal cancer and significance of PIK3CA mutations in HPV-associated head and neck cancer. Clin. Cancer Res. 20: 2300-2311.
    • (2014) Clin. Cancer Res. , vol.20 , pp. 2300-2311
    • Sewell, A.1
  • 18
    • 84880278585 scopus 로고    scopus 로고
    • Exploiting the head and neck cancer oncogenome: widespread PI3K-mTOR pathway alterations and novel molecular targets
    • Iglesias-Bartolome, R., D. Martin & J.S. Gutkind . 2013. Exploiting the head and neck cancer oncogenome: widespread PI3K-mTOR pathway alterations and novel molecular targets. Cancer Discov. 3: 722-725.
    • (2013) Cancer Discov , vol.3 , pp. 722-725
    • Iglesias-Bartolome, R.1    Martin, D.2    Gutkind, J.S.3
  • 19
    • 80052163601 scopus 로고    scopus 로고
    • Cancer: another NOTCH for cancer
    • Brakenhoff, R.H. 2011. Cancer: another NOTCH for cancer. Science 333: 1102-1103.
    • (2011) Science , vol.333 , pp. 1102-1103
    • Brakenhoff, R.H.1
  • 20
    • 84880063586 scopus 로고    scopus 로고
    • p53-based therapeutics for head and neck squamous cell carcinoma
    • Tassone, P. et al. 2013. p53-based therapeutics for head and neck squamous cell carcinoma. Oral Oncol. 49: 733-737.
    • (2013) Oral Oncol , vol.49 , pp. 733-737
    • Tassone, P.1
  • 21
    • 84885735554 scopus 로고    scopus 로고
    • Mutational landscape and significance across 12 major cancer types
    • Kandoth, C. et al. 2013. Mutational landscape and significance across 12 major cancer types. Nature 502: 333-339.
    • (2013) Nature , vol.502 , pp. 333-339
    • Kandoth, C.1
  • 23
    • 37349055876 scopus 로고    scopus 로고
    • TP53 mutations and survival in squamous-cell carcinoma of the head and neck
    • Poeta, M.L. et al. 2007. TP53 mutations and survival in squamous-cell carcinoma of the head and neck. N. Engl. J. Med. 357: 2552-2561.
    • (2007) N. Engl. J. Med , vol.357 , pp. 2552-2561
    • Poeta, M.L.1
  • 24
    • 84855443905 scopus 로고    scopus 로고
    • TP53 disruptive mutations lead to head and neck cancer treatment failure through inhibition of radiation-induced senescence
    • Skinner, H.D. et al. 2012. TP53 disruptive mutations lead to head and neck cancer treatment failure through inhibition of radiation-induced senescence. Clin. Cancer Res. 18: 290-300.
    • (2012) Clin. Cancer Res. , vol.18 , pp. 290-300
    • Skinner, H.D.1
  • 25
    • 0034086197 scopus 로고    scopus 로고
    • p53 alterations predict tumor response to neoadjuvant chemotherapy in head and neck squamous cell carcinoma: a prospective series
    • Cabelguenne, A. et al. 2000. p53 alterations predict tumor response to neoadjuvant chemotherapy in head and neck squamous cell carcinoma: a prospective series. J. Clin. Oncol. 18: 1465-1473.
    • (2000) J. Clin. Oncol. , vol.18 , pp. 1465-1473
    • Cabelguenne, A.1
  • 26
    • 77649207406 scopus 로고    scopus 로고
    • TP53 mutations and pathologic complete response to neoadjuvant cisplatin and fluorouracil chemotherapy in resected oral cavity squamous cell carcinoma
    • Perrone, F. et al. 2010. TP53 mutations and pathologic complete response to neoadjuvant cisplatin and fluorouracil chemotherapy in resected oral cavity squamous cell carcinoma. J. Clin. Oncol. 28: 761-766.
    • (2010) J. Clin. Oncol , vol.28 , pp. 761-766
    • Perrone, F.1
  • 27
    • 77649211801 scopus 로고    scopus 로고
    • Functional p53 status as a biomarker for chemotherapy response in oral-cavity cancer
    • Mroz, E.A. & J.W. Rocco . 2010. Functional p53 status as a biomarker for chemotherapy response in oral-cavity cancer. J. Clin. Oncol. 28: 715-717.
    • (2010) J. Clin. Oncol , vol.28 , pp. 715-717
    • Mroz, E.A.1    Rocco, J.W.2
  • 28
    • 84865285462 scopus 로고    scopus 로고
    • The p53-reactivating small-molecule RITA enhances cisplatin-induced cytotoxicity and apoptosis in head and neck cancer
    • Roh, J.L. et al. 2012. The p53-reactivating small-molecule RITA enhances cisplatin-induced cytotoxicity and apoptosis in head and neck cancer. Cancer Lett. 325: 35-41.
    • (2012) Cancer Lett , vol.325 , pp. 35-41
    • Roh, J.L.1
  • 29
    • 70349348934 scopus 로고    scopus 로고
    • A phase 2 trial of surgery with perioperative INGN 201 (Ad5CMV-p53) gene therapy followed by chemoradiotherapy for advanced, resectable squamous cell carcinoma of the oral cavity, oropharynx, hypopharynx, and larynx: report of the Southwest Oncology Group
    • Yoo, G.H. et al. 2009. A phase 2 trial of surgery with perioperative INGN 201 (Ad5CMV-p53) gene therapy followed by chemoradiotherapy for advanced, resectable squamous cell carcinoma of the oral cavity, oropharynx, hypopharynx, and larynx: report of the Southwest Oncology Group. Arch. Otolaryngol.-Head Neck Surg. 135: 869-874.
    • (2009) Arch. Otolaryngol.-Head Neck Surg , vol.135 , pp. 869-874
    • Yoo, G.H.1
  • 30
    • 84055212017 scopus 로고    scopus 로고
    • Phase I trial of ALT-801, an interleukin-2/T-cell receptor fusion protein targeting p53 (aa264-272)/HLA-A*0201 complex, in patients with advanced malignancies
    • Fishman, M.N. et al. 2011. Phase I trial of ALT-801, an interleukin-2/T-cell receptor fusion protein targeting p53 (aa264-272)/HLA-A*0201 complex, in patients with advanced malignancies. Clin. Cancer Res. 17: 7765-7775.
    • (2011) Clin. Cancer Res. , vol.17 , pp. 7765-7775
    • Fishman, M.N.1
  • 31
  • 32
    • 84880259398 scopus 로고    scopus 로고
    • Frequent mutation of the PI3K pathway in head and neck cancer defines predictive biomarkers
    • Lui, V.W. et al. 2013. Frequent mutation of the PI3K pathway in head and neck cancer defines predictive biomarkers. Cancer Discov. 3: 761-769.
    • (2013) Cancer Discov , vol.3 , pp. 761-769
    • Lui, V.W.1
  • 33
    • 84902681730 scopus 로고    scopus 로고
    • Genomic analysis of head and neck squamous cell carcinoma cell lines and human tumors: a rational approach to preclinical model selection
    • Li, H. et al. 2014. Genomic analysis of head and neck squamous cell carcinoma cell lines and human tumors: a rational approach to preclinical model selection. Molec. Cancer Res. 12: 571-582.
    • (2014) Molec. Cancer Res , vol.12 , pp. 571-582
    • Li, H.1
  • 34
    • 84877584488 scopus 로고    scopus 로고
    • A phase 1 study of everolimus plus docetaxel plus cisplatin as induction chemotherapy for patients with locally and/or regionally advanced head and neck cancer
    • Fury, M.G. et al. 2013. A phase 1 study of everolimus plus docetaxel plus cisplatin as induction chemotherapy for patients with locally and/or regionally advanced head and neck cancer. Cancer 119: 1823-1831.
    • (2013) Cancer , vol.119 , pp. 1823-1831
    • Fury, M.G.1
  • 35
    • 84875722517 scopus 로고    scopus 로고
    • A phase II study of temsirolimus and erlotinib in patients with recurrent and/or metastatic, platinum-refractory head and neck squamous cell carcinoma
    • Bauman, J.E. et al. 2013. A phase II study of temsirolimus and erlotinib in patients with recurrent and/or metastatic, platinum-refractory head and neck squamous cell carcinoma. Oral Oncol. 49: 461-467.
    • (2013) Oral Oncol , vol.49 , pp. 461-467
    • Bauman, J.E.1
  • 36
    • 79751472667 scopus 로고    scopus 로고
    • Tumor-derived JAGGED1 promotes osteolytic bone metastasis of breast cancer by engaging notch signaling in bone cells
    • Sethi, N. et al. 2011. Tumor-derived JAGGED1 promotes osteolytic bone metastasis of breast cancer by engaging notch signaling in bone cells. Cancer Cell. 19: 192-205.
    • (2011) Cancer Cell , vol.19 , pp. 192-205
    • Sethi, N.1
  • 37
    • 84896082963 scopus 로고    scopus 로고
    • From fly wings to targeted cancer therapies: a centennial for notch signaling
    • Ntziachristos, P. et al. 2014. From fly wings to targeted cancer therapies: a centennial for notch signaling. Cancer Cell. 25: 318-334.
    • (2014) Cancer Cell , vol.25 , pp. 318-334
    • Ntziachristos, P.1
  • 38
    • 80055092549 scopus 로고    scopus 로고
    • Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma
    • Wang, N.J. et al. 2011. Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma. Proc. Natl. Acad. Sci. USA 108: 17761-17766.
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 17761-17766
    • Wang, N.J.1
  • 39
    • 0037370310 scopus 로고    scopus 로고
    • Notch1 functions as a tumor suppressor in mouse skin
    • Nicolas, M. et al. 2003. Notch1 functions as a tumor suppressor in mouse skin. Nat. Genet. 33: 416-421.
    • (2003) Nat. Genet , vol.33 , pp. 416-421
    • Nicolas, M.1
  • 40
    • 33747891694 scopus 로고    scopus 로고
    • Impaired notch signaling promotes de novo squamous cell carcinoma formation
    • Proweller, A. et al. 2006. Impaired notch signaling promotes de novo squamous cell carcinoma formation. Cancer Res. 66: 7438-7444.
    • (2006) Cancer Res , vol.66 , pp. 7438-7444
    • Proweller, A.1
  • 41
    • 79960036578 scopus 로고    scopus 로고
    • Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia
    • Puente, X.S. et al. 2011. Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia. Nature 475: 101-105.
    • (2011) Nature , vol.475 , pp. 101-105
    • Puente, X.S.1
  • 42
    • 5044225888 scopus 로고    scopus 로고
    • Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia
    • Weng, A.P. et al. 2004. Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia. Science 306: 269-271.
    • (2004) Science , vol.306 , pp. 269-271
    • Weng, A.P.1
  • 43
    • 84894281594 scopus 로고    scopus 로고
    • Activation of the NOTCH pathway in head and neck cancer
    • Sun, W. et al. 2014. Activation of the NOTCH pathway in head and neck cancer. Cancer Res. 74: 1091-1104.
    • (2014) Cancer Res , vol.74 , pp. 1091-1104
    • Sun, W.1
  • 44
    • 84893448476 scopus 로고    scopus 로고
    • Common and complex Notch1 mutations in Chinese oral squamous cell carcinoma
    • Song, X. et al. 2014. Common and complex Notch1 mutations in Chinese oral squamous cell carcinoma. Clin. Cancer Res. 20: 701-710.
    • (2014) Clin. Cancer Res. , vol.20 , pp. 701-710
    • Song, X.1
  • 45
    • 84864005118 scopus 로고    scopus 로고
    • Phase I pharmacologic and pharmacodynamic study of the gamma secretase (Notch) inhibitor MK-0752 in adult patients with advanced solid tumors
    • Krop, I. et al. 2012. Phase I pharmacologic and pharmacodynamic study of the gamma secretase (Notch) inhibitor MK-0752 in adult patients with advanced solid tumors. J. Clin. Oncol. 30: 2307-2313.
    • (2012) J. Clin. Oncol. , vol.30 , pp. 2307-2313
    • Krop, I.1
  • 46
    • 84864018642 scopus 로고    scopus 로고
    • Phase I study of RO4929097, a gamma secretase inhibitor of Notch signaling, in patients with refractory metastatic or locally advanced solid tumors
    • Tolcher, A.W. et al. 2012. Phase I study of RO4929097, a gamma secretase inhibitor of Notch signaling, in patients with refractory metastatic or locally advanced solid tumors. J. Clin. Oncol. 30: 2348-2353.
    • (2012) J. Clin. Oncol. , vol.30 , pp. 2348-2353
    • Tolcher, A.W.1
  • 47
    • 84908261808 scopus 로고    scopus 로고
    • Characterization of HPV and host genome interactions in primary head and neck cancers
    • Parfenov, M. et al. 2014. Characterization of HPV and host genome interactions in primary head and neck cancers. Proc. Natl. Acad. Sci. USA. 111: 15544-15549.
    • (2014) Proc. Natl. Acad. Sci. USA. , vol.111 , pp. 15544-15549
    • Parfenov, M.1
  • 48
    • 84922394461 scopus 로고    scopus 로고
    • Multi-tiered genomic analysis of head and neck cancer ties TP53 mutation to 3p loss
    • Gross, A.M. et al. 2014. Multi-tiered genomic analysis of head and neck cancer ties TP53 mutation to 3p loss. Nat. Genet. 46: 939-943.
    • (2014) Nat. Genet , vol.46 , pp. 939-943
    • Gross, A.M.1


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