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Volumn 49, Issue 8, 2013, Pages 733-737

P53-based therapeutics for head and neck squamous cell carcinoma

Author keywords

Anti cancer therapeutics; Gene therapy; Head and neck cancer; Human papillomavirus; Oral cancer; Tumor suppressor gene p53

Indexed keywords

CISPLATIN; COMPLEMENTARY DNA; FLUOROURACIL; LONTUCIREV; METHOTREXATE; MICRORNA 200C; MICRORNA 34A; PROTEIN P53; RECOMBINANT ADENOVIRUS P53; UNCLASSIFIED DRUG;

EID: 84880063586     PISSN: 13688375     EISSN: 18790593     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2013.03.447     Document Type: Review
Times cited : (31)

References (41)
  • 2
    • 2342595266 scopus 로고    scopus 로고
    • A causal role for human papillomavirus in head and neck cancer
    • M.L. Gillison, and D.R. Lowy A causal role for human papillomavirus in head and neck cancer Lancet 363 9420 2004 1488 1489
    • (2004) Lancet , vol.363 , Issue.9420 , pp. 1488-1489
    • Gillison, M.L.1    Lowy, D.R.2
  • 3
    • 84858749922 scopus 로고    scopus 로고
    • Human papillomavirus, smoking, and head and neck cancer
    • P. Sinha, H.L. Logan, and W.M. Mendenhall Human papillomavirus, smoking, and head and neck cancer Am J Otolaryngol 33 1 2012 130 136
    • (2012) Am J Otolaryngol , vol.33 , Issue.1 , pp. 130-136
    • Sinha, P.1    Logan, H.L.2    Mendenhall, W.M.3
  • 5
    • 0018348655 scopus 로고
    • T antigen is bound to a host protein in SV40-transformed cells
    • D.P. Lane, and L.V. Crawford T antigen is bound to a host protein in SV40-transformed cells Nature 278 5701 1979 261 263
    • (1979) Nature , vol.278 , Issue.5701 , pp. 261-263
    • Lane, D.P.1    Crawford, L.V.2
  • 7
    • 0029888514 scopus 로고    scopus 로고
    • Biological and clinical importance of the p53 tumor suppressor gene
    • V.E. Velculescu, and W.S. El-Deiry Biological and clinical importance of the p53 tumor suppressor gene Clin Chem 42 6 Pt 1 1996 858 868
    • (1996) Clin Chem , vol.42 , Issue.6 PART 1 , pp. 858-868
    • Velculescu, V.E.1    El-Deiry, W.S.2
  • 8
    • 0037399623 scopus 로고    scopus 로고
    • The p53 network in head and neck cancer
    • M. Gasco, and T. Crook The p53 network in head and neck cancer Oral Oncol 39 3 2003 222 231
    • (2003) Oral Oncol , vol.39 , Issue.3 , pp. 222-231
    • Gasco, M.1    Crook, T.2
  • 9
    • 0036258111 scopus 로고    scopus 로고
    • The IARC TP53 database: New online mutation analysis and recommendations to users
    • M. Olivier, R. Eeles, M. Hollstein, M.A. Khan, C.C. Harris, and P. Hainaut The IARC TP53 database: new online mutation analysis and recommendations to users Hum Mutat 19 6 2002 607 614
    • (2002) Hum Mutat , vol.19 , Issue.6 , pp. 607-614
    • Olivier, M.1    Eeles, R.2    Hollstein, M.3    Khan, M.A.4    Harris, C.C.5    Hainaut, P.6
  • 10
    • 0036022408 scopus 로고    scopus 로고
    • Transfection of mutant p53 gene depresses X-ray- or CDDP-induced apoptosis in a human squamous cell carcinoma of the head and neck
    • K. Ohnishi, I. Ota, A. Takahashi, K. Yane, H. Matsumoto, and T. Ohnishi Transfection of mutant p53 gene depresses X-ray- or CDDP-induced apoptosis in a human squamous cell carcinoma of the head and neck Apoptosis 7 4 2002 367 372
    • (2002) Apoptosis , vol.7 , Issue.4 , pp. 367-372
    • Ohnishi, K.1    Ota, I.2    Takahashi, A.3    Yane, K.4    Matsumoto, H.5    Ohnishi, T.6
  • 12
    • 0029017333 scopus 로고
    • Apoptosis induction mediated by wild-type p53 adenoviral gene transfer in squamous cell carcinoma of the head and neck
    • T.J. Liu, A.K. El-Naggar, T.J. McDonnell, K.D. Steck, M. Wang, and D.L. Taylor Apoptosis induction mediated by wild-type p53 adenoviral gene transfer in squamous cell carcinoma of the head and neck Cancer Res 55 14 1995 3117 3122
    • (1995) Cancer Res , vol.55 , Issue.14 , pp. 3117-3122
    • Liu, T.J.1    El-Naggar, A.K.2    McDonnell, T.J.3    Steck, K.D.4    Wang, M.5    Taylor, D.L.6
  • 13
    • 0030969022 scopus 로고    scopus 로고
    • P53 mediated sensitization of squamous cell carcinoma of the head and neck to radiotherapy
    • K.F. Pirollo, Z. Hao, A. Rait, Y.J. Jang, W.E. Fee Jr., and P. Ryan P53 mediated sensitization of squamous cell carcinoma of the head and neck to radiotherapy Oncogene 14 14 1997 1735 1746
    • (1997) Oncogene , vol.14 , Issue.14 , pp. 1735-1746
    • Pirollo, K.F.1    Hao, Z.2    Rait, A.3    Jang, Y.J.4    Fee, Jr.W.E.5    Ryan, P.6
  • 14
    • 78651358753 scopus 로고    scopus 로고
    • Head and neck cancer: Response to p53-based therapeutics
    • J. Nemunaitis, and J. Nemunaitis Head and neck cancer: response to p53-based therapeutics Head Neck 33 1 2011 131 134
    • (2011) Head Neck , vol.33 , Issue.1 , pp. 131-134
    • Nemunaitis, J.1    Nemunaitis, J.2
  • 15
    • 0031750168 scopus 로고    scopus 로고
    • Adenovirus-mediated p53 gene transfer in patients with advanced recurrent head and neck squamous cell carcinoma
    • G.L. Clayman, A.K. El-Naggar, S.M. Lippman, Y.C. Henderson, M. Frederick, and J.A. Merritt Adenovirus-mediated p53 gene transfer in patients with advanced recurrent head and neck squamous cell carcinoma J Clin Oncol 16 6 1998 2221 2232
    • (1998) J Clin Oncol , vol.16 , Issue.6 , pp. 2221-2232
    • Clayman, G.L.1    El-Naggar, A.K.2    Lippman, S.M.3    Henderson, Y.C.4    Frederick, M.5    Merritt, J.A.6
  • 16
    • 70349348934 scopus 로고    scopus 로고
    • A phase 2 trial of surgery with perioperative INGN 201 (Ad5CMV-p53) gene therapy followed by chemoradiotherapy for advanced, resectable squamous cell carcinoma of the oral cavity, oropharynx, hypopharynx, and larynx: Report of the Southwest Oncology Group
    • G.H. Yoo, J. Moon, M. Leblanc, F. Lonardo, S. Urba, and H. Kim A phase 2 trial of surgery with perioperative INGN 201 (Ad5CMV-p53) gene therapy followed by chemoradiotherapy for advanced, resectable squamous cell carcinoma of the oral cavity, oropharynx, hypopharynx, and larynx: report of the Southwest Oncology Group Arch Otolaryngol Head Neck Surg 135 9 2009 869 874
    • (2009) Arch Otolaryngol Head Neck Surg , vol.135 , Issue.9 , pp. 869-874
    • Yoo, G.H.1    Moon, J.2    Leblanc, M.3    Lonardo, F.4    Urba, S.5    Kim, H.6
  • 17
    • 64149107093 scopus 로고    scopus 로고
    • Phase i study of repeated intraepithelial delivery of adenoviral p53 in patients with dysplastic oral leukoplakia
    • S. Zhang, Y. Li, L. Li, Y. Zhang, N. Gao, and Z. Zhang Phase I study of repeated intraepithelial delivery of adenoviral p53 in patients with dysplastic oral leukoplakia J Oral Maxillofac Surg 67 5 2009 1074 1082
    • (2009) J Oral Maxillofac Surg , vol.67 , Issue.5 , pp. 1074-1082
    • Zhang, S.1    Li, Y.2    Li, L.3    Zhang, Y.4    Gao, N.5    Zhang, Z.6
  • 18
    • 70350705951 scopus 로고    scopus 로고
    • In vitro and clinical studies of gene therapy with recombinant human adenovirus-p53 injection for oral leukoplakia
    • Y. Li, L.J. Li, S.T. Zhang, L.J. Wang, Z. Zhang, and N. Gao In vitro and clinical studies of gene therapy with recombinant human adenovirus-p53 injection for oral leukoplakia Clin Cancer Res 15 21 2009 6724 6731
    • (2009) Clin Cancer Res , vol.15 , Issue.21 , pp. 6724-6731
    • Li, Y.1    Li, L.J.2    Zhang, S.T.3    Wang, L.J.4    Zhang, Z.5    Gao, N.6
  • 19
    • 0035863458 scopus 로고    scopus 로고
    • Phase II trial of intratumoral administration of ONYX-015, a replication-selective adenovirus, in patients with refractory head and neck cancer
    • J. Nemunaitis, F. Khuri, I. Ganly, J. Arseneau, M. Posner, and E. Vokes Phase II trial of intratumoral administration of ONYX-015, a replication-selective adenovirus, in patients with refractory head and neck cancer J Clin Oncol 19 2 2001 289 298
    • (2001) J Clin Oncol , vol.19 , Issue.2 , pp. 289-298
    • Nemunaitis, J.1    Khuri, F.2    Ganly, I.3    Arseneau, J.4    Posner, M.5    Vokes, E.6
  • 20
    • 0344188096 scopus 로고    scopus 로고
    • An adenovirus mutant that replicates selectively in p53-deficient human tumor cells
    • J.R. Bischoff, D.H. Kirn, A. Williams, C. Heise, S. Horn, and M. Muna An adenovirus mutant that replicates selectively in p53-deficient human tumor cells Science 264 1996 373 376
    • (1996) Science , vol.264 , pp. 373-376
    • Bischoff, J.R.1    Kirn, D.H.2    Williams, A.3    Heise, C.4    Horn, S.5    Muna, M.6
  • 21
    • 0030917202 scopus 로고    scopus 로고
    • Onyx-015, an E1B gene-attenuated adenovirus, causes tumour specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents
    • H. Heise, A. Sampson-Johannes, A. Williams, F. McCormack, D.D. Von Hoff, and D.H. Kirn Onyx-015, an E1B gene-attenuated adenovirus, causes tumour specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents Nat Med 3 1997 639 645
    • (1997) Nat Med , vol.3 , pp. 639-645
    • Heise, H.1    Sampson-Johannes, A.2    Williams, A.3    McCormack, F.4    Von Hoff, D.D.5    Kirn, D.H.6
  • 22
    • 12944328660 scopus 로고    scopus 로고
    • A phase i study of Onyx-015, an E1B attenuated adenovirus, administered intratumorally to patients with recurrent head and neck cancer
    • I. Ganly, D. Kirn, G. Eckhardt, G.I. Rodriguez, D.S. Soutar, and R. Otto A phase I study of Onyx-015, an E1B attenuated adenovirus, administered intratumorally to patients with recurrent head and neck cancer Clin Cancer Res 6 3 2000 798 806
    • (2000) Clin Cancer Res , vol.6 , Issue.3 , pp. 798-806
    • Ganly, I.1    Kirn, D.2    Eckhardt, G.3    Rodriguez, G.I.4    Soutar, D.S.5    Otto, R.6
  • 23
    • 0034990761 scopus 로고    scopus 로고
    • Intravenous infusion of a replication-selective adenovirus (ONYX-015) in cancer patients: Safety, feasibility and biological activity
    • J. Nemunaitis, C. Cunningham, A. Buchanan, A. Blackburn, G. Edelman, and P. Maples Intravenous infusion of a replication-selective adenovirus (ONYX-015) in cancer patients: safety, feasibility and biological activity Gene Ther 8 10 2001 746 759
    • (2001) Gene Ther , vol.8 , Issue.10 , pp. 746-759
    • Nemunaitis, J.1    Cunningham, C.2    Buchanan, A.3    Blackburn, A.4    Edelman, G.5    Maples, P.6
  • 24
    • 0033835016 scopus 로고    scopus 로고
    • A prospective phase II trial of ONYX-015 adenovirus and chemotherapy in recurrent squamous cell carcinoma of the head and neck (the Baylor experience)
    • J.P. Lamont, J. Nemunaitis, J.A. Kuhn, S.A. Landers, and T.M. McCarty A prospective phase II trial of ONYX-015 adenovirus and chemotherapy in recurrent squamous cell carcinoma of the head and neck (the Baylor experience) Ann Surg Oncol 7 8 2000 588 592
    • (2000) Ann Surg Oncol , vol.7 , Issue.8 , pp. 588-592
    • Lamont, J.P.1    Nemunaitis, J.2    Kuhn, J.A.3    Landers, S.A.4    McCarty, T.M.5
  • 25
    • 0033831080 scopus 로고    scopus 로고
    • A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer
    • F.R. Khuri, J. Nemunaitis, I. Ganly, J. Arseneau, I.F. Tannock, and L. Romel A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer Nat Med 6 8 2000 879 885
    • (2000) Nat Med , vol.6 , Issue.8 , pp. 879-885
    • Khuri, F.R.1    Nemunaitis, J.2    Ganly, I.3    Arseneau, J.4    Tannock, I.F.5    Romel, L.6
  • 26
    • 0036128899 scopus 로고    scopus 로고
    • Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound
    • V.J. Bykov, N. Issaeva, A. Shilov, M. Hultcrantz, E. Pugacheva, and P. Chumakov Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound Nat Med 8 3 2002 282 288
    • (2002) Nat Med , vol.8 , Issue.3 , pp. 282-288
    • Bykov, V.J.1    Issaeva, N.2    Shilov, A.3    Hultcrantz, M.4    Pugacheva, E.5    Chumakov, P.6
  • 27
    • 21344434834 scopus 로고    scopus 로고
    • Selective induction of apoptosis in mutant p53 premalignant and malignant cancer cells by PRIMA-1 through the c-Jun-NH2-kinase pathway
    • Y. Li, Y. Mao, P.W. Brandt-Rauf, A.C. Williams, and R.L. Fine Selective induction of apoptosis in mutant p53 premalignant and malignant cancer cells by PRIMA-1 through the c-Jun-NH2-kinase pathway Mol Cancer Ther 4 6 2005 901 909
    • (2005) Mol Cancer Ther , vol.4 , Issue.6 , pp. 901-909
    • Li, Y.1    Mao, Y.2    Brandt-Rauf, P.W.3    Williams, A.C.4    Fine, R.L.5
  • 28
    • 79551512486 scopus 로고    scopus 로고
    • P53-Reactivating small molecules induce apoptosis and enhance chemotherapeutic cytotoxicity in head and neck squamous cell carcinoma
    • J.L. Roh, S.K. Kang, I. Minn, J.A. Califano, D. Sidransky, and W.M. Koch P53-Reactivating small molecules induce apoptosis and enhance chemotherapeutic cytotoxicity in head and neck squamous cell carcinoma Oral Oncol 47 1 2011 8 15
    • (2011) Oral Oncol , vol.47 , Issue.1 , pp. 8-15
    • Roh, J.L.1    Kang, S.K.2    Minn, I.3    Califano, J.A.4    Sidransky, D.5    Koch, W.M.6
  • 29
    • 0033601370 scopus 로고    scopus 로고
    • Pharmacological rescue of mutant p53 conformation and function
    • B.A. Foster, H.A. Coffey, M.J. Morin, and F. Rastinejad Pharmacological rescue of mutant p53 conformation and function Science 286 5449 1999 2507 2510
    • (1999) Science , vol.286 , Issue.5449 , pp. 2507-2510
    • Foster, B.A.1    Coffey, H.A.2    Morin, M.J.3    Rastinejad, F.4
  • 30
    • 0031583962 scopus 로고    scopus 로고
    • Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53
    • R. Honda, H. Tanaka, and H. Yasuda Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53 FEBS Lett 420 1 1997 25 27
    • (1997) FEBS Lett , vol.420 , Issue.1 , pp. 25-27
    • Honda, R.1    Tanaka, H.2    Yasuda, H.3
  • 31
    • 32444449180 scopus 로고    scopus 로고
    • Small-molecule MDM2 antagonists reveal aberrant p53 signaling in cancer: Implications for therapy
    • C. Tovar, J. Rosinski, Z. Filipovic, B. Higgins, K. Kolinsky, and H. Hilton Small-molecule MDM2 antagonists reveal aberrant p53 signaling in cancer: implications for therapy Proc Natl Acad Sci USA 103 6 2006 1888 1893
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.6 , pp. 1888-1893
    • Tovar, C.1    Rosinski, J.2    Filipovic, Z.3    Higgins, B.4    Kolinsky, K.5    Hilton, H.6
  • 32
    • 10744221485 scopus 로고    scopus 로고
    • In vivo activation of the p53 pathway by small-molecule antagonists of MDM2
    • L.T. Vassilev, B.T. Vu, B. Graves, D. Carvajal, F. Podlaski, and Z. Filipovic In vivo activation of the p53 pathway by small-molecule antagonists of MDM2 Science 303 5659 2004 844 848
    • (2004) Science , vol.303 , Issue.5659 , pp. 844-848
    • Vassilev, L.T.1    Vu, B.T.2    Graves, B.3    Carvajal, D.4    Podlaski, F.5    Filipovic, Z.6
  • 33
    • 11144315535 scopus 로고    scopus 로고
    • Small molecule RITA binds to p53, blocks p53-HDM-2 interaction and activates p53 function in tumors
    • N. Issaeva, P. Bozko, M. Enge, M. Protopopova, L.G. Verhoef, and M. Masucci Small molecule RITA binds to p53, blocks p53-HDM-2 interaction and activates p53 function in tumors Nat Med 10 12 2004 1321 1328
    • (2004) Nat Med , vol.10 , Issue.12 , pp. 1321-1328
    • Issaeva, N.1    Bozko, P.2    Enge, M.3    Protopopova, M.4    Verhoef, L.G.5    Masucci, M.6
  • 34
    • 84865285462 scopus 로고    scopus 로고
    • The p53-reactivating small-molecule RITA enhances cisplatin-induced cytotoxicity and apoptosis in head and neck cancer
    • J.L. Roh, J.H. Ko, S.J. Moon, C.H. Ryu, J.Y. Choi, and W.M. Koch The p53-reactivating small-molecule RITA enhances cisplatin-induced cytotoxicity and apoptosis in head and neck cancer Cancer Lett 325 1 2012 35 41
    • (2012) Cancer Lett , vol.325 , Issue.1 , pp. 35-41
    • Roh, J.L.1    Ko, J.H.2    Moon, S.J.3    Ryu, C.H.4    Choi, J.Y.5    Koch, W.M.6
  • 35
    • 0025932933 scopus 로고
    • A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18
    • J.M. Huibregtse, M. Scheffner, and P.M. Howley A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18 EMBO J 10 1991 4129 4135
    • (1991) EMBO J , vol.10 , pp. 4129-4135
    • Huibregtse, J.M.1    Scheffner, M.2    Howley, P.M.3
  • 36
    • 0027358723 scopus 로고
    • The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53
    • M. Scheffner, J.M. Huibregtse, R.D. Vierstra, and P.M. Howley The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53 Cell 75 1993 495 505
    • (1993) Cell , vol.75 , pp. 495-505
    • Scheffner, M.1    Huibregtse, J.M.2    Vierstra, R.D.3    Howley, P.M.4
  • 37
    • 0032513114 scopus 로고    scopus 로고
    • The role of E6AP in the regulation of p53 protein levels in human papillomavirus (HPV)-positive and HPV-negative cells
    • A.L. Talis, J.M. Huibregtse, and P.M. Howley The role of E6AP in the regulation of p53 protein levels in human papillomavirus (HPV)-positive and HPV-negative cells J Biol Chem 273 1998 6439 6445
    • (1998) J Biol Chem , vol.273 , pp. 6439-6445
    • Talis, A.L.1    Huibregtse, J.M.2    Howley, P.M.3
  • 38
    • 0032768483 scopus 로고    scopus 로고
    • The human papillomavirus type 16 E6 oncoprotein can down-regulate p53 activity by targeting the transcriptional coactivator BP/p300
    • H. Zimmermann, R. Degenkolbe, H.U. Bernard, and M.J. O'Connor The human papillomavirus type 16 E6 oncoprotein can down-regulate p53 activity by targeting the transcriptional coactivator BP/p300 J Virol 73 1999 6209 6219
    • (1999) J Virol , vol.73 , pp. 6209-6219
    • Zimmermann, H.1    Degenkolbe, R.2    Bernard, H.U.3    O'Connor, M.J.4
  • 39
    • 0033568491 scopus 로고    scopus 로고
    • The E6 protein of human papillomavirus type 16 binds to and inhibits co-activation by CBP and p300
    • D. Patel, S.M. Huang, L.A. Baglia, and D.J. McCance The E6 protein of human papillomavirus type 16 binds to and inhibits co-activation by CBP and p300 EMBO J 18 1999 5061 5072
    • (1999) EMBO J , vol.18 , pp. 5061-5072
    • Patel, D.1    Huang, S.M.2    Baglia, L.A.3    McCance, D.J.4
  • 40
    • 12344295621 scopus 로고    scopus 로고
    • E6 oncoprotein represses p53-dependent gene activation via inhibition of protein acetylation independently of inducing p53 degradation
    • M.C. Thomas, and C.M. Chiang E6 oncoprotein represses p53-dependent gene activation via inhibition of protein acetylation independently of inducing p53 degradation Mol Cell 17 2005 251 264
    • (2005) Mol Cell , vol.17 , pp. 251-264
    • Thomas, M.C.1    Chiang, C.M.2
  • 41
    • 84894563712 scopus 로고    scopus 로고
    • Targeting HPV16 E6-p300 interaction reactivates p53 and inhibits the tumorigenicity of HPV-positive head and neck squamous cell carcinoma
    • doi: [Epub ahead of print]
    • Xie X, Piao L, Bullock BN, Smith A, Su T, Zhang M, et al. Targeting HPV16 E6-p300 interaction reactivates p53 and inhibits the tumorigenicity of HPV-positive head and neck squamous cell carcinoma. Oncogene 2013. doi: http://dx.doi.org/10.1038/onc.2013.25 [Epub ahead of print].
    • (2013) Oncogene
    • Xie, X.1    Piao, L.2    Bullock, B.N.3    Smith, A.4    Su, T.5    Zhang, M.6


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