-
1
-
-
80052565730
-
Human papillomavirus and rising oropharyngeal cancer incidence in the United States.
-
10.1200/JCO.2011.36.4596, 3221528, 21969503
-
Chaturvedi AK, Engels EA, Pfeiffer RM, Hernandez BY, Xiao W, Kim E, Jiang B, Goodman MT, Sibug-Saber M, Cozen W, Liu L, Lynch CF, Wentzensen N, Jordan RC, Altekruse S, Anderson WF, Rosenberg PS, Gillison ML. Human papillomavirus and rising oropharyngeal cancer incidence in the United States. J Clin Oncol 2011, 29:4294-4301. 10.1200/JCO.2011.36.4596, 3221528, 21969503.
-
(2011)
J Clin Oncol
, vol.29
, pp. 4294-4301
-
-
Chaturvedi, A.K.1
Engels, E.A.2
Pfeiffer, R.M.3
Hernandez, B.Y.4
Xiao, W.5
Kim, E.6
Jiang, B.7
Goodman, M.T.8
Sibug-Saber, M.9
Cozen, W.10
Liu, L.11
Lynch, C.F.12
Wentzensen, N.13
Jordan, R.C.14
Altekruse, S.15
Anderson, W.F.16
Rosenberg, P.S.17
Gillison, M.L.18
-
2
-
-
70350646787
-
Human papillomavirus and head and neck cancer.
-
10.1097/COC.0b013e31818b8fee, 19652580
-
Mendenhall WM, Logan HL. Human papillomavirus and head and neck cancer. Am J Clin Oncol 2009, 32:535-539. 10.1097/COC.0b013e31818b8fee, 19652580.
-
(2009)
Am J Clin Oncol
, vol.32
, pp. 535-539
-
-
Mendenhall, W.M.1
Logan, H.L.2
-
3
-
-
39649109915
-
Improved survival of patients with human papillomavirus-positive head and neck squamous cell carcinoma in a prospective clinical trial.
-
10.1093/jnci/djn011, 18270337
-
Fakhry C, Westra WH, Li S, Cmelak A, Ridge JA, Pinto H, Forastiere A, Gillison ML. Improved survival of patients with human papillomavirus-positive head and neck squamous cell carcinoma in a prospective clinical trial. J Natl Cancer Inst 2008, 100:261-269. 10.1093/jnci/djn011, 18270337.
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 261-269
-
-
Fakhry, C.1
Westra, W.H.2
Li, S.3
Cmelak, A.4
Ridge, J.A.5
Pinto, H.6
Forastiere, A.7
Gillison, M.L.8
-
4
-
-
80052177544
-
Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1.
-
10.1126/science.1206923, 3162986, 21798897
-
Agrawal N, Frederick MJ, Pickering CR, Bettegowda C, Chang K, Li RJ, Fakhry C, Xie TX, Zhang J, Wang J, Zhang N, El-Naggar AK, Jasser SA, Weinstein JN, Trevino L, Drummond JA, Muzny DM, Wu Y, Wood LD, Hruban RH, Westra WH, Koch WM, Califano JA, Gibbs RA, Sidransky D, Vogelstein B, Velculescu VE, Papadopoulos N, Wheeler DA, Kinzler KW, et al. Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1. Science 2011, 333:1154-1157. 10.1126/science.1206923, 3162986, 21798897.
-
(2011)
Science
, vol.333
, pp. 1154-1157
-
-
Agrawal, N.1
Frederick, M.J.2
Pickering, C.R.3
Bettegowda, C.4
Chang, K.5
Li, R.J.6
Fakhry, C.7
Xie, T.X.8
Zhang, J.9
Wang, J.10
Zhang, N.11
El-Naggar, A.K.12
Jasser, S.A.13
Weinstein, J.N.14
Trevino, L.15
Drummond, J.A.16
Muzny, D.M.17
Wu, Y.18
Wood, L.D.19
Hruban, R.H.20
Westra, W.H.21
Koch, W.M.22
Califano, J.A.23
Gibbs, R.A.24
Sidransky, D.25
Vogelstein, B.26
Velculescu, V.E.27
Papadopoulos, N.28
Wheeler, D.A.29
Kinzler, K.W.30
more..
-
5
-
-
80052158097
-
The mutational landscape of head and neck squamous cell carcinoma.
-
10.1126/science.1208130, 3415217, 21798893
-
Stransky N, Egloff AM, Tward AD, Kostic AD, Cibulskis K, Sivachenko A, Kryukov GV, Lawrence MS, Sougnez C, McKenna A, Shefler E, Ramos AH, Stojanov P, Carter SL, Voet D, Cortes ML, Auclair D, Berger MF, Saksena G, Guiducci C, Onofrio RC, Parkin M, Romkes M, Weissfeld JL, Seethala RR, Wang L, Rangel-Escareno C, Fernandez-Lopez JC, Hidalgo-Miranda A, Melendez-Zajgla J, et al. The mutational landscape of head and neck squamous cell carcinoma. Science 2011, 333:1157-1160. 10.1126/science.1208130, 3415217, 21798893.
-
(2011)
Science
, vol.333
, pp. 1157-1160
-
-
Stransky, N.1
Egloff, A.M.2
Tward, A.D.3
Kostic, A.D.4
Cibulskis, K.5
Sivachenko, A.6
Kryukov, G.V.7
Lawrence, M.S.8
Sougnez, C.9
McKenna, A.10
Shefler, E.11
Ramos, A.H.12
Stojanov, P.13
Carter, S.L.14
Voet, D.15
Cortes, M.L.16
Auclair, D.17
Berger, M.F.18
Saksena, G.19
Guiducci, C.20
Onofrio, R.C.21
Parkin, M.22
Romkes, M.23
Weissfeld, J.L.24
Seethala, R.R.25
Wang, L.26
Rangel-Escareno, C.27
Fernandez-Lopez, J.C.28
Hidalgo-Miranda, A.29
Melendez-Zajgla, J.30
more..
-
6
-
-
80053520906
-
Evaluation of human papilloma virus diagnostic testing in oropharyngeal squamous cell carcinoma: sensitivity, specificity, and prognostic discrimination.
-
10.1158/1078-0432.CCR-11-0388, 3188400, 21969383
-
Schache AG, Liloglou T, Risk JM, Filia A, Jones TM, Sheard J, Woolgar JA, Helliwell TR, Triantafyllou A, Robinson M, Sloan P, Harvey-Woodworth C, Sisson D, Shaw RJ. Evaluation of human papilloma virus diagnostic testing in oropharyngeal squamous cell carcinoma: sensitivity, specificity, and prognostic discrimination. Clin Cancer Res 2011, 17:6262-6271. 10.1158/1078-0432.CCR-11-0388, 3188400, 21969383.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 6262-6271
-
-
Schache, A.G.1
Liloglou, T.2
Risk, J.M.3
Filia, A.4
Jones, T.M.5
Sheard, J.6
Woolgar, J.A.7
Helliwell, T.R.8
Triantafyllou, A.9
Robinson, M.10
Sloan, P.11
Harvey-Woodworth, C.12
Sisson, D.13
Shaw, R.J.14
-
7
-
-
85081458325
-
-
http://www.sanger.ac.uk/genetics/CGP/cosmic/
-
-
-
-
8
-
-
67649884743
-
Fast and accurate short read alignment with Burrows-Wheeler transform.
-
10.1093/bioinformatics/btp324, 2705234, 19451168
-
Li H, Durbin R. Fast and accurate short read alignment with Burrows-Wheeler transform. Bioinformatics 2009, 25:1754-1760. 10.1093/bioinformatics/btp324, 2705234, 19451168.
-
(2009)
Bioinformatics
, vol.25
, pp. 1754-1760
-
-
Li, H.1
Durbin, R.2
-
9
-
-
85081456727
-
-
http://picard.sourceforge.net
-
-
-
-
10
-
-
68549104404
-
The Sequence Alignment/Map format and SAMtools.
-
10.1093/bioinformatics/btp352, 2723002, 19505943
-
Li H, Handsaker B, Wysoker A, Fennell T, Ruan J, Homer N, Marth G, Abecasis G, Durbin R. The Sequence Alignment/Map format and SAMtools. Bioinformatics 2009, 25:2078-2079. 10.1093/bioinformatics/btp352, 2723002, 19505943.
-
(2009)
Bioinformatics
, vol.25
, pp. 2078-2079
-
-
Li, H.1
Handsaker, B.2
Wysoker, A.3
Fennell, T.4
Ruan, J.5
Homer, N.6
Marth, G.7
Abecasis, G.8
Durbin, R.9
-
11
-
-
79955483667
-
A framework for variation discovery and genotyping using next-generation DNA sequencing data.
-
10.1038/ng.806, 3083463, 21478889
-
DePristo MA, Banks E, Poplin R, Garimella KV, Maguire JR, Hartl C, Philippakis AA, del Angel G, Rivas MA, Hanna M, McKenna A, Fennell TJ, Kernytsky AM, Sivachenko AY, Cibulskis K, Gabriel SB, Altshuler D, Daly MJ. A framework for variation discovery and genotyping using next-generation DNA sequencing data. Nat Genet 2011, 43:491-498. 10.1038/ng.806, 3083463, 21478889.
-
(2011)
Nat Genet
, vol.43
, pp. 491-498
-
-
DePristo, M.A.1
Banks, E.2
Poplin, R.3
Garimella, K.V.4
Maguire, J.R.5
Hartl, C.6
Philippakis, A.A.7
del Angel, G.8
Rivas, M.A.9
Hanna, M.10
McKenna, A.11
Fennell, T.J.12
Kernytsky, A.M.13
Sivachenko, A.Y.14
Cibulskis, K.15
Gabriel, S.B.16
Altshuler, D.17
Daly, M.J.18
-
12
-
-
78651330430
-
COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer.
-
10.1093/nar/gkq929, 3013785, 20952405
-
Forbes SA, Bindal N, Bamford S, Cole C, Kok CY, Beare D, Jia M, Shepherd R, Leung K, Menzies A, Teague JW, Campbell PJ, Stratton MR, Futreal PA. COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer. Nucleic Acids Res 2011, 39:D945-950. 10.1093/nar/gkq929, 3013785, 20952405.
-
(2011)
Nucleic Acids Res
, vol.39
-
-
Forbes, S.A.1
Bindal, N.2
Bamford, S.3
Cole, C.4
Kok, C.Y.5
Beare, D.6
Jia, M.7
Shepherd, R.8
Leung, K.9
Menzies, A.10
Teague, J.W.11
Campbell, P.J.12
Stratton, M.R.13
Futreal, P.A.14
-
13
-
-
80755159050
-
How to apply de Bruijn graphs to genome assembly.
-
10.1038/nbt.2023, 22068540
-
Compeau PE, Pevzner PA, Tesler G. How to apply de Bruijn graphs to genome assembly. Nat Biotechnol 2011, 29:987-991. 10.1038/nbt.2023, 22068540.
-
(2011)
Nat Biotechnol
, vol.29
, pp. 987-991
-
-
Compeau, P.E.1
Pevzner, P.A.2
Tesler, G.3
-
14
-
-
85081454186
-
-
http://www.ncbi.nlm.nih.gov/projects/SNP/
-
-
-
-
15
-
-
84860782006
-
Absolute quantification of somatic DNA alterations in human cancer.
-
10.1038/nbt.2203, 22544022
-
Carter SL, Cibulskis K, Helman E, McKenna A, Shen H, Zack T, Laird PW, Onofrio RC, Winckler W, Weir BA, Beroukhim R, Pellman D, Levine DA, Lander ES, Meyerson M, Getz G. Absolute quantification of somatic DNA alterations in human cancer. Nat Biotechnol 2012, 30:413-421. 10.1038/nbt.2203, 22544022.
-
(2012)
Nat Biotechnol
, vol.30
, pp. 413-421
-
-
Carter, S.L.1
Cibulskis, K.2
Helman, E.3
McKenna, A.4
Shen, H.5
Zack, T.6
Laird, P.W.7
Onofrio, R.C.8
Winckler, W.9
Weir, B.A.10
Beroukhim, R.11
Pellman, D.12
Levine, D.A.13
Lander, E.S.14
Meyerson, M.15
Getz, G.16
-
16
-
-
78049248432
-
Allele-specific copy number analysis of tumors.
-
10.1073/pnas.1009843107, 2947907, 20837533
-
Van Loo P, Nordgard SH, Lingjaerde OC, Russnes HG, Rye IH, Sun W, Weigman VJ, Marynen P, Zetterberg A, Naume B, Perou CM, Borresen-Dale AL, Kristensen VN. Allele-specific copy number analysis of tumors. Proc Natl Acad Sci USA 2010, 107:16910-16915. 10.1073/pnas.1009843107, 2947907, 20837533.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 16910-16915
-
-
Van Loo, P.1
Nordgard, S.H.2
Lingjaerde, O.C.3
Russnes, H.G.4
Rye, I.H.5
Sun, W.6
Weigman, V.J.7
Marynen, P.8
Zetterberg, A.9
Naume, B.10
Perou, C.M.11
Borresen-Dale, A.L.12
Kristensen, V.N.13
-
17
-
-
77956690576
-
A statistical approach for detecting genomic aberrations in heterogeneous tumor samples from single nucleotide polymorphism genotyping data.
-
2965384, 20858232
-
Yau C, Mouradov D, Jorissen RN, Colella S, Mirza G, Steers G, Harris A, Ragoussis J, Sieber O, Holmes CC. A statistical approach for detecting genomic aberrations in heterogeneous tumor samples from single nucleotide polymorphism genotyping data. Genome Biol 2010, 11:R92. 2965384, 20858232.
-
(2010)
Genome Biol
, vol.11
-
-
Yau, C.1
Mouradov, D.2
Jorissen, R.N.3
Colella, S.4
Mirza, G.5
Steers, G.6
Harris, A.7
Ragoussis, J.8
Sieber, O.9
Holmes, C.C.10
-
18
-
-
77950561234
-
A rapid, sensitive, reproducible and cost-effective method for mutation profiling of colon cancer and metastatic lymph nodes.
-
10.1186/1471-2407-10-101, 2845115, 20233444
-
Fumagalli D, Gavin PG, Taniyama Y, Kim SI, Choi HJ, Paik S, Pogue-Geile KL. A rapid, sensitive, reproducible and cost-effective method for mutation profiling of colon cancer and metastatic lymph nodes. BMC Cancer 2010, 10:101. 10.1186/1471-2407-10-101, 2845115, 20233444.
-
(2010)
BMC Cancer
, vol.10
, pp. 101
-
-
Fumagalli, D.1
Gavin, P.G.2
Taniyama, Y.3
Kim, S.I.4
Choi, H.J.5
Paik, S.6
Pogue-Geile, K.L.7
-
19
-
-
84873939792
-
Identification and functional validation of HPV-mediated hypermethylation in head and neck squamous cell carcinoma.
-
10.1186/gm419, 3706778, 23419152
-
Lechner M, Fenton T, West J, Wilson G, Feber A, Henderson S, Thirlwell C, Dibra HK, Jay A, Butcher L, Chakravarthy AR, Gratrix F, Patel N, Vaz F, O'Flynn P, Kalavrezos N, Teschendorff AE, Boshoff C, Beck S. Identification and functional validation of HPV-mediated hypermethylation in head and neck squamous cell carcinoma. Genome Med 2013, 5:15. 10.1186/gm419, 3706778, 23419152.
-
(2013)
Genome Med
, vol.5
, pp. 15
-
-
Lechner, M.1
Fenton, T.2
West, J.3
Wilson, G.4
Feber, A.5
Henderson, S.6
Thirlwell, C.7
Dibra, H.K.8
Jay, A.9
Butcher, L.10
Chakravarthy, A.R.11
Gratrix, F.12
Patel, N.13
Vaz, F.14
O'Flynn, P.15
Kalavrezos, N.16
Teschendorff, A.E.17
Boshoff, C.18
Beck, S.19
-
20
-
-
85081456322
-
-
http://bioc.ism.ac.jp/2.10/bioc/html/DNAcopy.html
-
-
-
-
21
-
-
34147104969
-
A faster circular binary segmentation algorithm for the analysis of array CGH data.
-
10.1093/bioinformatics/btl646, 17234643
-
Venkatraman ES, Olshen AB. A faster circular binary segmentation algorithm for the analysis of array CGH data. Bioinformatics 2007, 23:657-663. 10.1093/bioinformatics/btl646, 17234643.
-
(2007)
Bioinformatics
, vol.23
, pp. 657-663
-
-
Venkatraman, E.S.1
Olshen, A.B.2
-
22
-
-
84883050588
-
CNA profiling using high-density DNA methylation arrays.
-
In revision
-
Feber A, Guilhamon P, Lechner M, Fenton T, Wilson GA, Thirlwell C, Flanagan AM, Teschendorff AE, Kelly JD, Beck S. CNA profiling using high-density DNA methylation arrays. Genome Biol 2013, In revision.
-
(2013)
Genome Biol
-
-
Feber, A.1
Guilhamon, P.2
Lechner, M.3
Fenton, T.4
Wilson, G.A.5
Thirlwell, C.6
Flanagan, A.M.7
Teschendorff, A.E.8
Kelly, J.D.9
Beck, S.10
-
23
-
-
84862777505
-
Clinical assessment of PTEN loss in endometrial carcinoma: immunohistochemistry outperforms gene sequencing.
-
10.1038/modpathol.2011.208, 3341518, 22301702
-
Djordjevic B, Hennessy BT, Li J, Barkoh BA, Luthra R, Mills GB, Broaddus RR. Clinical assessment of PTEN loss in endometrial carcinoma: immunohistochemistry outperforms gene sequencing. Mod Pathol 2012, 25:699-708. 10.1038/modpathol.2011.208, 3341518, 22301702.
-
(2012)
Mod Pathol
, vol.25
, pp. 699-708
-
-
Djordjevic, B.1
Hennessy, B.T.2
Li, J.3
Barkoh, B.A.4
Luthra, R.5
Mills, G.B.6
Broaddus, R.R.7
-
24
-
-
33745190482
-
Cyclin D1 protein overexpression and CCND1 amplification in breast carcinomas: an immunohistochemical and chromogenic in situ hybridisation analysis.
-
10.1038/modpathol.3800621, 16648863
-
Reis-Filho JS, Savage K, Lambros MB, James M, Steele D, Jones RL, Dowsett M. Cyclin D1 protein overexpression and CCND1 amplification in breast carcinomas: an immunohistochemical and chromogenic in situ hybridisation analysis. Mod Pathol 2006, 19:999-1009. 10.1038/modpathol.3800621, 16648863.
-
(2006)
Mod Pathol
, vol.19
, pp. 999-1009
-
-
Reis-Filho, J.S.1
Savage, K.2
Lambros, M.B.3
James, M.4
Steele, D.5
Jones, R.L.6
Dowsett, M.7
-
25
-
-
10044248559
-
Human papillomavirus-associated head and neck cancer is a distinct epidemiologic, clinical, and molecular entity.
-
10.1053/j.seminoncol.2004.09.011, 15599852
-
Gillison ML. Human papillomavirus-associated head and neck cancer is a distinct epidemiologic, clinical, and molecular entity. Semin Oncol 2004, 31:744-754. 10.1053/j.seminoncol.2004.09.011, 15599852.
-
(2004)
Semin Oncol
, vol.31
, pp. 744-754
-
-
Gillison, M.L.1
-
26
-
-
77951022892
-
Human papillomavirus and oropharyngeal cancer: what you need to know in 2009.
-
10.1007/s11864-009-0113-5, 19768554
-
Gillespie MB, Rubinchik S, Hoel B, Sutkowski N. Human papillomavirus and oropharyngeal cancer: what you need to know in 2009. Curr Treat Options Oncol 2009, 10:296-307. 10.1007/s11864-009-0113-5, 19768554.
-
(2009)
Curr Treat Options Oncol
, vol.10
, pp. 296-307
-
-
Gillespie, M.B.1
Rubinchik, S.2
Hoel, B.3
Sutkowski, N.4
-
27
-
-
78650626081
-
The molecular biology of head and neck cancer.
-
10.1038/nrc2982, 21160525
-
Leemans CR, Braakhuis BJ, Brakenhoff RH. The molecular biology of head and neck cancer. Nat Rev Cancer 2011, 11:9-22. 10.1038/nrc2982, 21160525.
-
(2011)
Nat Rev Cancer
, vol.11
, pp. 9-22
-
-
Leemans, C.R.1
Braakhuis, B.J.2
Brakenhoff, R.H.3
-
28
-
-
79551715546
-
Comprehensive mapping of p53 pathway alterations reveals an apparent role for both SNP309 and MDM2 amplification in sarcomagenesis.
-
10.1158/1078-0432.CCR-10-2050, 21159888
-
Ito M, Barys L, O'Reilly T, Young S, Gorbatcheva B, Monahan J, Zumstein-Mecker S, Choong PF, Dickinson I, Crowe P, Hemmings C, Desai J, Thomas DM, Lisztwan J. Comprehensive mapping of p53 pathway alterations reveals an apparent role for both SNP309 and MDM2 amplification in sarcomagenesis. Clin Cancer Res 2011, 17:416-426. 10.1158/1078-0432.CCR-10-2050, 21159888.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 416-426
-
-
Ito, M.1
Barys, L.2
O'Reilly, T.3
Young, S.4
Gorbatcheva, B.5
Monahan, J.6
Zumstein-Mecker, S.7
Choong, P.F.8
Dickinson, I.9
Crowe, P.10
Hemmings, C.11
Desai, J.12
Thomas, D.M.13
Lisztwan, J.14
-
29
-
-
34248379012
-
Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database.
-
10.1002/humu.20495, 17311302
-
Petitjean A, Mathe E, Kato S, Ishioka C, Tavtigian SV, Hainaut P, Olivier M. Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database. Hum Mutat 2007, 28:622-629. 10.1002/humu.20495, 17311302.
-
(2007)
Hum Mutat
, vol.28
, pp. 622-629
-
-
Petitjean, A.1
Mathe, E.2
Kato, S.3
Ishioka, C.4
Tavtigian, S.V.5
Hainaut, P.6
Olivier, M.7
-
30
-
-
0035120289
-
Chromosomal alterations in squamous cell carcinomas of the head and neck: window to the biology of disease.
-
10.1002/1097-0347(200103)23:3<238::AID-HED1025>3.0.CO;2-H, 11428456
-
Gollin SM. Chromosomal alterations in squamous cell carcinomas of the head and neck: window to the biology of disease. Head Neck 2001, 23:238-253. 10.1002/1097-0347(200103)23:3<238::AID-HED1025>3.0.CO;2-H, 11428456.
-
(2001)
Head Neck
, vol.23
, pp. 238-253
-
-
Gollin, S.M.1
-
31
-
-
84866002291
-
The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data.
-
10.1158/2159-8290.CD-12-0095, 22588877
-
Cerami E, Gao J, Dogrusoz U, Gross BE, Sumer SO, Aksoy BA, Jacobsen A, Byrne CJ, Heuer ML, Larsson E, Antipin Y, Reva B, Goldberg AP, Sander C, Schultz N. The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data. Cancer Discov 2012, 2:401-404. 10.1158/2159-8290.CD-12-0095, 22588877.
-
(2012)
Cancer Discov
, vol.2
, pp. 401-404
-
-
Cerami, E.1
Gao, J.2
Dogrusoz, U.3
Gross, B.E.4
Sumer, S.O.5
Aksoy, B.A.6
Jacobsen, A.7
Byrne, C.J.8
Heuer, M.L.9
Larsson, E.10
Antipin, Y.11
Reva, B.12
Goldberg, A.P.13
Sander, C.14
Schultz, N.15
-
32
-
-
84866294247
-
Prognostic significance of cyclinD1 amplification and the co-alteration of cyclinD1/pRb/ppRb in patients with esophageal squamous cell carcinoma.
-
10.1111/j.1442-2050.2011.01291.x, 22150974
-
Wang MT, Chen G, An SJ, Chen ZH, Huang ZM, Xiao P, Ben XS, Xie Z, Chen SL, Luo DL, Tang JM, Lin JY, Zhang XC, Wu YL. Prognostic significance of cyclinD1 amplification and the co-alteration of cyclinD1/pRb/ppRb in patients with esophageal squamous cell carcinoma. Dis Esophagus 2012, 25:664-670. 10.1111/j.1442-2050.2011.01291.x, 22150974.
-
(2012)
Dis Esophagus
, vol.25
, pp. 664-670
-
-
Wang, M.T.1
Chen, G.2
An, S.J.3
Chen, Z.H.4
Huang, Z.M.5
Xiao, P.6
Ben, X.S.7
Xie, Z.8
Chen, S.L.9
Luo, D.L.10
Tang, J.M.11
Lin, J.Y.12
Zhang, X.C.13
Wu, Y.L.14
-
33
-
-
84860363833
-
MTOR as a molecular target in HPV-associated oral and cervical squamous carcinomas.
-
10.1158/1078-0432.CCR-11-2824, 3443560, 22409888
-
Molinolo AA, Marsh C, El Dinali M, Gangane N, Jennison K, Hewitt S, Patel V, Seiwert TY, Gutkind JS. mTOR as a molecular target in HPV-associated oral and cervical squamous carcinomas. Clin Cancer Res 2012, 18:2558-2568. 10.1158/1078-0432.CCR-11-2824, 3443560, 22409888.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 2558-2568
-
-
Molinolo, A.A.1
Marsh, C.2
El Dinali, M.3
Gangane, N.4
Jennison, K.5
Hewitt, S.6
Patel, V.7
Seiwert, T.Y.8
Gutkind, J.S.9
-
34
-
-
79960354038
-
PI3K-dependent phosphorylation of Fbw7 modulates substrate degradation and activity.
-
10.1016/j.febslet.2011.05.036, 21620836
-
Schulein C, Eilers M, Popov N. PI3K-dependent phosphorylation of Fbw7 modulates substrate degradation and activity. FEBS Lett 2011, 585:2151-2157. 10.1016/j.febslet.2011.05.036, 21620836.
-
(2011)
FEBS Lett
, vol.585
, pp. 2151-2157
-
-
Schulein, C.1
Eilers, M.2
Popov, N.3
-
35
-
-
84855685279
-
An integrated view of cyclin E function and regulation.
-
10.4161/cc.11.1.18775, 3272232, 22186781
-
Siu KT, Rosner MR, Minella AC. An integrated view of cyclin E function and regulation. Cell Cycle 2012, 11:57-64. 10.4161/cc.11.1.18775, 3272232, 22186781.
-
(2012)
Cell Cycle
, vol.11
, pp. 57-64
-
-
Siu, K.T.1
Rosner, M.R.2
Minella, A.C.3
-
36
-
-
78650305754
-
The favorable effect of activating NOTCH1 receptor mutations on long-term outcome in T-ALL patients treated on the ALL-BFM 2000 protocol can be separated from FBXW7 loss of function.
-
10.1038/leu.2010.203, 3035973, 20944675
-
Kox C, Zimmermann M, Stanulla M, Leible S, Schrappe M, Ludwig WD, Koehler R, Tolle G, Bandapalli OR, Breit S, Muckenthaler MU, Kulozik AE. The favorable effect of activating NOTCH1 receptor mutations on long-term outcome in T-ALL patients treated on the ALL-BFM 2000 protocol can be separated from FBXW7 loss of function. Leukemia 2010, 24:2005-2013. 10.1038/leu.2010.203, 3035973, 20944675.
-
(2010)
Leukemia
, vol.24
, pp. 2005-2013
-
-
Kox, C.1
Zimmermann, M.2
Stanulla, M.3
Leible, S.4
Schrappe, M.5
Ludwig, W.D.6
Koehler, R.7
Tolle, G.8
Bandapalli, O.R.9
Breit, S.10
Muckenthaler, M.U.11
Kulozik, A.E.12
-
37
-
-
80052158097
-
The mutational landscape of head and neck squamous cell carcinoma.
-
10.1126/science.1208130, 3415217, 21798893
-
Stransky N, Egloff AM, Tward AD, Kostic AD, Cibulskis K, Sivachenko A, Kryukov GV, Lawrence M, Sougnez C, McKenna A, Shefler E, Ramos AH, Stojanov P, Carter SL, Voet D, Cortes ML, Auclair D, Berger MF, Saksena G, Guiducci C, Onofrio R, Parkin M, Romkes M, Weissfeld JL, Seethala RR, Wang L, Rangel-Escareno C, Fernandez-Lopez JC, Hidalgo-Miranda A, Melendez-Zajgla J, et al. The mutational landscape of head and neck squamous cell carcinoma. Science 2011, 333:1157-1160. 10.1126/science.1208130, 3415217, 21798893.
-
(2011)
Science
, vol.333
, pp. 1157-1160
-
-
Stransky, N.1
Egloff, A.M.2
Tward, A.D.3
Kostic, A.D.4
Cibulskis, K.5
Sivachenko, A.6
Kryukov, G.V.7
Lawrence, M.8
Sougnez, C.9
McKenna, A.10
Shefler, E.11
Ramos, A.H.12
Stojanov, P.13
Carter, S.L.14
Voet, D.15
Cortes, M.L.16
Auclair, D.17
Berger, M.F.18
Saksena, G.19
Guiducci, C.20
Onofrio, R.21
Parkin, M.22
Romkes, M.23
Weissfeld, J.L.24
Seethala, R.R.25
Wang, L.26
Rangel-Escareno, C.27
Fernandez-Lopez, J.C.28
Hidalgo-Miranda, A.29
Melendez-Zajgla, J.30
more..
-
38
-
-
80052177544
-
Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1.
-
10.1126/science.1206923, 3162986, 21798897
-
Agrawal N, Frederick MJ, Pickering CR, Bettegowda C, Chang K, Li RJ, Fakhry C, Xie TX, Zhang J, Wang J, Zhang N, El-Naggar AK, Jasser SA, Weinstein JN, Trevino L, Drummond JA, Muzny DM, Wu Y, Wood LD, Hruban RH, Westra WH, Koch WM, Califano JA, Gibbs RA, Sidransky D, Vogelstein B, Velculescu VE, Papadopoulos N, Wheeler DA, Kinzler KW, et al. Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1. Science 2011, 333:1154-1157. 10.1126/science.1206923, 3162986, 21798897.
-
(2011)
Science
, vol.333
, pp. 1154-1157
-
-
Agrawal, N.1
Frederick, M.J.2
Pickering, C.R.3
Bettegowda, C.4
Chang, K.5
Li, R.J.6
Fakhry, C.7
Xie, T.X.8
Zhang, J.9
Wang, J.10
Zhang, N.11
El-Naggar, A.K.12
Jasser, S.A.13
Weinstein, J.N.14
Trevino, L.15
Drummond, J.A.16
Muzny, D.M.17
Wu, Y.18
Wood, L.D.19
Hruban, R.H.20
Westra, W.H.21
Koch, W.M.22
Califano, J.A.23
Gibbs, R.A.24
Sidransky, D.25
Vogelstein, B.26
Velculescu, V.E.27
Papadopoulos, N.28
Wheeler, D.A.29
Kinzler, K.W.30
more..
-
39
-
-
84855439033
-
Smoking history and lung carcinoma: KRAS mutation is an early hit in lung adenocarcinoma development.
-
10.1016/j.lungcan.2011.07.013, 21839537
-
Thunnissen FB, Prinsen C, Hol B, Van der Drift M, Vesin A, Brambilla C, Montuenga L, Field JK. Smoking history and lung carcinoma: KRAS mutation is an early hit in lung adenocarcinoma development. Lung Cancer 2012, 75:156-160. 10.1016/j.lungcan.2011.07.013, 21839537.
-
(2012)
Lung Cancer
, vol.75
, pp. 156-160
-
-
Thunnissen, F.B.1
Prinsen, C.2
Hol, B.3
Van der Drift, M.4
Vesin, A.5
Brambilla, C.6
Montuenga, L.7
Field, J.K.8
-
40
-
-
0035872475
-
A simple specific pattern of chromosomal aberrations at early stages of head and neck squamous cell carcinomas: PIK3CA but not p63 gene as a likely target of 3q26-qter gains.
-
Redon R, Muller D, Caulee K, Wanherdrick K, Abecassis J, du Manoir S. A simple specific pattern of chromosomal aberrations at early stages of head and neck squamous cell carcinomas: PIK3CA but not p63 gene as a likely target of 3q26-qter gains. Cancer Res 2001, 61:4122-4129.
-
(2001)
Cancer Res
, vol.61
, pp. 4122-4129
-
-
Redon, R.1
Muller, D.2
Caulee, K.3
Wanherdrick, K.4
Abecassis, J.5
Du Manoir, S.6
-
41
-
-
34548450823
-
Phosphoinositide kinase-3 status associated with presence or absence of human papillomavirus in head and neck squamous cell carcinomas.
-
Yarbrough WG, Whigham A, Brown B, Roach M, Slebos R. Phosphoinositide kinase-3 status associated with presence or absence of human papillomavirus in head and neck squamous cell carcinomas. Int J Radiat Oncol Biol Phys 2007, 69:S98-101.
-
(2007)
Int J Radiat Oncol Biol Phys
, vol.69
-
-
Yarbrough, W.G.1
Whigham, A.2
Brown, B.3
Roach, M.4
Slebos, R.5
-
42
-
-
77955804088
-
Progressive 3q amplification consistently targets SOX2 in preinvasive squamous lung cancer.
-
10.1164/rccm.201001-0005OC, 2902760, 20299530
-
McCaughan F, Pole JC, Bankier AT, Konfortov BA, Carroll B, Falzon M, Rabbitts TH, George PJ, Dear PH, Rabbitts PH. Progressive 3q amplification consistently targets SOX2 in preinvasive squamous lung cancer. Am J Respir Crit Care Med 2010, 182:83-91. 10.1164/rccm.201001-0005OC, 2902760, 20299530.
-
(2010)
Am J Respir Crit Care Med
, vol.182
, pp. 83-91
-
-
McCaughan, F.1
Pole, J.C.2
Bankier, A.T.3
Konfortov, B.A.4
Carroll, B.5
Falzon, M.6
Rabbitts, T.H.7
George, P.J.8
Dear, P.H.9
Rabbitts, P.H.10
-
43
-
-
77957065335
-
SOX2 identified as a target gene for the amplification at 3q26 that is frequently detected in esophageal squamous cell carcinoma.
-
10.1016/j.cancergencyto.2010.01.023, 20875870
-
Gen Y, Yasui K, Zen Y, Zen K, Dohi O, Endo M, Tsuji K, Wakabayashi N, Itoh Y, Naito Y, Taniwaki M, Nakanuma Y, Okanoue T, Yoshikawa T. SOX2 identified as a target gene for the amplification at 3q26 that is frequently detected in esophageal squamous cell carcinoma. Cancer Genet Cytogenet 2010, 202:82-93. 10.1016/j.cancergencyto.2010.01.023, 20875870.
-
(2010)
Cancer Genet Cytogenet
, vol.202
, pp. 82-93
-
-
Gen, Y.1
Yasui, K.2
Zen, Y.3
Zen, K.4
Dohi, O.5
Endo, M.6
Tsuji, K.7
Wakabayashi, N.8
Itoh, Y.9
Naito, Y.10
Taniwaki, M.11
Nakanuma, Y.12
Okanoue, T.13
Yoshikawa, T.14
-
44
-
-
74949090477
-
Recurrent copy number gain of transcription factor SOX2 and corresponding high protein expression in oral squamous cell carcinoma.
-
10.1002/gcc.20714, 19787784
-
Freier K, Knoepfle K, Flechtenmacher C, Pungs S, Devens F, Toedt G, Hofele C, Joos S, Lichter P, Radlwimmer B. Recurrent copy number gain of transcription factor SOX2 and corresponding high protein expression in oral squamous cell carcinoma. Genes Chromosomes Cancer 2010, 49:9-16. 10.1002/gcc.20714, 19787784.
-
(2010)
Genes Chromosomes Cancer
, vol.49
, pp. 9-16
-
-
Freier, K.1
Knoepfle, K.2
Flechtenmacher, C.3
Pungs, S.4
Devens, F.5
Toedt, G.6
Hofele, C.7
Joos, S.8
Lichter, P.9
Radlwimmer, B.10
-
45
-
-
79551522569
-
Evidence for epithelial-mesenchymal transition in cancer stem cells of head and neck squamous cell carcinoma.
-
10.1371/journal.pone.0016466, 3029362, 21304586
-
Chen C, Wei Y, Hummel M, Hoffmann TK, Gross M, Kaufmann AM, Albers AE. Evidence for epithelial-mesenchymal transition in cancer stem cells of head and neck squamous cell carcinoma. PLoS One 2011, 6:e16466. 10.1371/journal.pone.0016466, 3029362, 21304586.
-
(2011)
PLoS One
, vol.6
-
-
Chen, C.1
Wei, Y.2
Hummel, M.3
Hoffmann, T.K.4
Gross, M.5
Kaufmann, A.M.6
Albers, A.E.7
-
46
-
-
80052977483
-
Localization-specific LKB1 loss in head and neck squamous cell carcinoma metastasis.
-
10.1002/hed.21638, 21928424
-
Kline ER, Muller S, Pan L, Tighiouart M, Chen ZG, Marcus AI. Localization-specific LKB1 loss in head and neck squamous cell carcinoma metastasis. Head Neck 2011, 33:1501-1512. 10.1002/hed.21638, 21928424.
-
(2011)
Head Neck
, vol.33
, pp. 1501-1512
-
-
Kline, E.R.1
Muller, S.2
Pan, L.3
Tighiouart, M.4
Chen, Z.G.5
Marcus, A.I.6
-
47
-
-
3042818799
-
Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome.
-
10.1101/gad.1199104, 443516, 15231735
-
Corradetti MN, Inoki K, Bardeesy N, DePinho RA, Guan KL. Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome. Genes Dev 2004, 18:1533-1538. 10.1101/gad.1199104, 443516, 15231735.
-
(2004)
Genes Dev
, vol.18
, pp. 1533-1538
-
-
Corradetti, M.N.1
Inoki, K.2
Bardeesy, N.3
DePinho, R.A.4
Guan, K.L.5
-
48
-
-
3142594193
-
The LKB1 tumor suppressor negatively regulates mTOR signaling.
-
10.1016/j.ccr.2004.06.007, 15261145
-
Shaw RJ, Bardeesy N, Manning BD, Lopez L, Kosmatka M, DePinho RA, Cantley LC. The LKB1 tumor suppressor negatively regulates mTOR signaling. Cancer Cell 2004, 6:91-99. 10.1016/j.ccr.2004.06.007, 15261145.
-
(2004)
Cancer Cell
, vol.6
, pp. 91-99
-
-
Shaw, R.J.1
Bardeesy, N.2
Manning, B.D.3
Lopez, L.4
Kosmatka, M.5
DePinho, R.A.6
Cantley, L.C.7
-
49
-
-
84857652259
-
MTOR inhibitors and its role in the treatment of head and neck squamous cell carcinoma.
-
10.1007/s11864-011-0180-2, 22282394
-
Nguyen SA, Walker D, Gillespie MB, Gutkind JS, Day TA. mTOR inhibitors and its role in the treatment of head and neck squamous cell carcinoma. Curr Treat Options Oncol 2012, 13:71-81. 10.1007/s11864-011-0180-2, 22282394.
-
(2012)
Curr Treat Options Oncol
, vol.13
, pp. 71-81
-
-
Nguyen, S.A.1
Walker, D.2
Gillespie, M.B.3
Gutkind, J.S.4
Day, T.A.5
|