Clinical, genomic, and metagenomic characterization of oral tongue squamous cell carcinoma in patients who do not smoke

Head and Neck

Volumn 37, Issue 11, 2015, Pages 1642-1649

  Li, Ryan ^a   Faden, Daniel L ^c   Fakhry, Carole ^a,b   Langelier, Chaz ^d   Jiao, Yuchen ^e   Wang, Yuxuan ^e   Wilkerson, Matthew D ^f,g   Pedamallu, Chandra Sekhar ^h,i   Old, Matthew ^j   Lang, James ^j   Loyo, Myriam ^a   Ahn, Sun Mi ^a   Tan, Marietta ^a   Gooi, Zhen ^a   Chan, Jason ^a   Richmon, Jeremy ^a   Wood, Laura D ^a   Hruban, Ralph H ^a   Bishop, Justin ^a   Westra, William H ^a   Chung, Christine H ^a   Califano, Joseph ^b   Gourin, Christine G ^a   Bettegowda, Chetan ^a   Meyerson, Matthew ^h,i,k   Papadopoulos, Nickolas ^e   Kinzler, Kenneth W ^e   Vogelstein, Bert ^e   Derisi, Joseph L ^c,l   Koch, Wayne M ^a   Agrawal, Nishant ^a,e   more..

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b GREATER BALTIMORE MEDICAL CENTER   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e JOHNS HOPKINS UNIVERSITY   (United States)

^f UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^g UNIVERSITY OF NORTH CAROLINA   (United States)

^h BROAD INSTITUTE OF MIT AND HARVARD   (United States)

ⁱ DANA FARBER CANCER INSTITUTE   (United States)

^j OHIO STATE UNIVERSITY   (United States)

^k HARVARD MEDICAL SCHOOL   (United States)

^l HOWARD HUGHES MEDICAL INSTITUTE   (United States)

more..

Author keywords

head and neck cancer; next generation sequencing; nonsmokers; oral tongue; squamous cell carcinoma

Indexed keywords

COMPLEMENTARY DNA; GENOMIC DNA; TRANSCRIPTOME; DNA; MESSENGER RNA; PROTEIN P53; TP53 PROTEIN, HUMAN;

ADULT; AGE; ARTICLE; CANCER PATIENT; CANCER SURGERY; CONTROLLED STUDY; DNA LIBRARY; EXOME; FEMALE; GENDER; GENE; GENE MUTATION; GENOMICS; HUMAN; MAJOR CLINICAL STUDY; MALE; METAGENOMICS; MISCELLANEOUS NAMED GROUPS; NONSMOKER; PRIORITY JOURNAL; RNA SEQUENCE; SEQUENCE ANALYSIS; SMOKING; SOMATIC MUTATION; TONGUE CARCINOMA; TP53 GENE; TUMOR VIRUS; VIRUS DETECTION; AGE DISTRIBUTION; CANCER STAGING; CARCINOMA, SQUAMOUS CELL; CLINICAL TRIAL; COHORT ANALYSIS; COMPARATIVE STUDY; FACTUAL DATABASE; GENETIC PREDISPOSITION; GENETICS; INCIDENCE; METAGENOME; MIDDLE AGED; MULTICENTER STUDY; MUTATION; PATHOLOGY; PROGNOSIS; RETROSPECTIVE STUDY; RISK ASSESSMENT; SEX RATIO; TONGUE NEOPLASMS; TUMOR INVASION;

ADULT; AGE DISTRIBUTION; CARCINOMA, SQUAMOUS CELL; COHORT STUDIES; DATABASES, FACTUAL; DNA, NEOPLASM; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOMICS; HUMANS; INCIDENCE; MALE; METAGENOME; MIDDLE AGED; MUTATION; NEOPLASM INVASIVENESS; NEOPLASM STAGING; PROGNOSIS; RETROSPECTIVE STUDIES; RISK ASSESSMENT; RNA, MESSENGER; SEX DISTRIBUTION; SMOKING; TONGUE NEOPLASMS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84944031585     PISSN: 10433074     EISSN: 10970347     Source Type: Journal    
DOI: 10.1002/hed.23807     Document Type: Article

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