Signaling pathways activated by a protease allergen in basophils

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 46, 2014, Pages E4963-E4971

  Rosenstein, Rachel K ^a   Bezbradica, Jelena S ^a   Yu, Shuang ^a   Medzhitov, Ruslan ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Allergen; Basophil; Signaling

Indexed keywords

ADAPTOR PROTEIN; CALCIUM ION; CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL; CELL SURFACE RECEPTOR; FC RECEPTOR; GLYCOGEN SYNTHASE KINASE 3BETA; I KAPPA B ALPHA; IMMUNOGLOBULIN E; INTERLEUKIN 13; INTERLEUKIN 3; INTERLEUKIN 33; INTERLEUKIN 4; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PAPAIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PHOSPHOLIPASE C GAMMA; PROTEIN KINASE B; PROTEIN KINASE SYK; PROTEINASE ACTIVATED RECEPTOR; STAT5 PROTEIN; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR NFAT; ALLERGEN; CALCIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; CYSTEINE PROTEINASE INHIBITOR; FCGR1 PROTEIN, MOUSE; IL33 PROTEIN, MOUSE; IMMUNOGLOBULIN E RECEPTOR; INTERLEUKIN DERIVATIVE; LEUCINE; N [N (3 CARBOXYOXIRANE 2 CARBONYL)LEUCYL]AGMATINE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BASOPHIL; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL ACTIVATION; CELL STIMULATION; CELL SURFACE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; EXTRACELLULAR CALCIUM; IMMUNE RESPONSE; IMMUNOGENICITY; IMMUNORECEPTOR TYROSINE BASED ACTIVATION MOTIF; IN VITRO STUDY; LEUKOCYTE ACTIVATION; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; PROTEIN CROSS LINKING; PROTEIN DEGRADATION; PROTEIN INDUCTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; ANALOGS AND DERIVATIVES; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; C57BL MOUSE; CALCIUM SIGNALING; CELL CULTURE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; GERMFREE ANIMAL; IMMUNIZATION; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY;

VERMES;

ADAPTOR PROTEIN COMPLEX SUBUNITS; ALLERGENS; ANIMALS; BASOPHILS; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS; CALCIUM SIGNALING; CELLS, CULTURED; CYSTEINE PROTEINASE INHIBITORS; GENE EXPRESSION REGULATION; IMMUNIZATION; INTERLEUKIN-13; INTERLEUKIN-33; INTERLEUKIN-4; INTERLEUKINS; LEUCINE; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; NFATC TRANSCRIPTION FACTORS; PAPAIN; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, IGE; RECEPTORS, IGG; SIGNAL TRANSDUCTION; SPECIFIC PATHOGEN-FREE ORGANISMS;

EID: 84919489944     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1418959111     Document Type: Article

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