The kynurenine pathway of tryptophan degradation is activated during osteoblastogenesis

Stem Cells

Volumn 33, Issue 1, 2015, Pages 111-121

  Vidal, Christopher ^a   Li, Wei ^a   Santner Nanan, Brigitte ^b   Lim, Chai K ^c,d   Guillemin, Gilles J ^c,d   Ball, Helen J ^e   Hunt, Nicholas H ^e   Nanan, Ralph ^b   Duque, Gustavo ^a  

^a Musculoskeletal Ageing Research Program ^*  (United Kingdom)

^b UNIVERSITY OF SYDNEY   (Australia)

^c MACQUARIE UNIVERSITY   (Australia)

^d UNIVERSITY OF NEW SOUTH WALES   (Australia)

^e UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Interferon gamma; Kynurenine; Mesenchymal stem cells; Osteoblastogenesis; Osteoporosis; Picolinic acid

Indexed keywords

CALCIUM; GAMMA INTERFERON; INDOLEAMINE 2,3 DIOXYGENASE; KYNURENINE; PARATHYROID HORMONE; PICOLINIC ACID; SEROTONIN; SMALL INTERFERING RNA; TRYPTOPHAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM BLOOD LEVEL; CELL COUNT; CELL DIFFERENTIATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME INHIBITION; FEMALE; GENETIC ASSOCIATION; HUMAN; HUMAN CELL; IN VITRO STUDY; KNOCKOUT MOUSE; MESENCHYMAL STEM CELL; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOBLASTOGENESIS; OSTEOCLAST; OSTEOPENIA; PARATHYROID HORMONE BLOOD LEVEL; PHENOTYPE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SEROTONIN BLOOD LEVEL; UPREGULATION; WILD TYPE; ANIMAL; C57BL MOUSE; CYTOLOGY; MESENCHYMAL STROMA CELL; METABOLISM; OSTEOPOROSIS; PATHOLOGY; PHYSIOLOGY;

MUS;

ANIMALS; CELL DIFFERENTIATION; FEMALE; HUMANS; KYNURENINE; MESENCHYMAL STROMAL CELLS; MICE; MICE, INBRED C57BL; OSTEOBLASTS; OSTEOPOROSIS; TRYPTOPHAN;

EID: 84919451382     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.1836     Document Type: Article

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