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Volumn 5, Issue OCT, 2014, Pages

Regulation of macrophage polarization by RON receptor tyrosine kinase signaling

Author keywords

Immune therapy; Macrophages; Polarization; RON signaling; Tumor promotion

Indexed keywords

ARGINASE 1; BETA INTERFERON; CYTOKINE; GAMMA INTERFERON; GROWTH FACTOR; INTERFERON REGULATORY FACTOR; INTERLEUKIN 13; INTERLEUKIN 4; LIPOPOLYSACCHARIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN TYROSINE KINASE; RON PROTEIN TYROSINE KINASE; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84919426734     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2014.00546     Document Type: Article
Times cited : (27)

References (43)
  • 1
    • 67649404131 scopus 로고    scopus 로고
    • Blood monocytes: development, heterogeneity, and relationship with dendritic cells
    • Auffray C, Sieweke MH, Geissmann F. Blood monocytes: development, heterogeneity, and relationship with dendritic cells. Annu Rev Immunol (2009) 27:669-92. doi: 10.1146/annurev.immunol.021908.132557
    • (2009) Annu Rev Immunol , vol.27 , pp. 669-692
    • Auffray, C.1    Sieweke, M.H.2    Geissmann, F.3
  • 2
    • 76249095169 scopus 로고    scopus 로고
    • Development of monocytes, macrophages, and dendritic cells
    • Geissmann F, Manz MG, Jung S, Sieweke MH, Merad M, Ley K. Development of monocytes, macrophages, and dendritic cells. Science (2010) 327(5966):656-61. doi:10.1126/science.1178331
    • (2010) Science , vol.327 , Issue.5966 , pp. 656-661
    • Geissmann, F.1    Manz, M.G.2    Jung, S.3    Sieweke, M.H.4    Merad, M.5    Ley, K.6
  • 3
    • 84908507825 scopus 로고    scopus 로고
    • Molecular control of monocyte development
    • Terry RL, Miller SD. Molecular control of monocyte development. Cell Immunol (2014). doi:10.1016/j.cellimm.2014.02.008
    • (2014) Cell Immunol
    • Terry, R.L.1    Miller, S.D.2
  • 4
    • 84873743410 scopus 로고    scopus 로고
    • M1 and M2 macrophages: oracles of health and disease
    • Mills CD. M1 and M2 macrophages: oracles of health and disease. Crit Rev Immunol (2012) 32(6):463-88. doi:10.1615/CritRevImmunol.v32.i6.10
    • (2012) Crit Rev Immunol , vol.32 , Issue.6 , pp. 463-488
    • Mills, C.D.1
  • 5
    • 84857883847 scopus 로고    scopus 로고
    • Macrophage plasticity and polarization: in vivo veritas
    • Sica A, Mantovani A. Macrophage plasticity and polarization: in vivo veritas. J Clin Invest (2012) 122(3):787-95. doi:10.1172/JCI59643
    • (2012) J Clin Invest , vol.122 , Issue.3 , pp. 787-795
    • Sica, A.1    Mantovani, A.2
  • 6
    • 84897556094 scopus 로고    scopus 로고
    • The M1 and M2 paradigm of macrophage activation: time for reassessment
    • Martinez FO, Gordon S. The M1 and M2 paradigm of macrophage activation: time for reassessment. F1000Prime Rep (2014) 6:13. doi:10.12703/P6-13
    • (2014) F1000Prime Rep , vol.6 , pp. 13
    • Martinez, F.O.1    Gordon, S.2
  • 7
    • 84904394690 scopus 로고    scopus 로고
    • Macrophage activation and polarization: nomenclature and experimental guidelines
    • Murray PJ, Allen JE, Biswas SK, Fisher EA, Gilroy DW, Goerdt S, et al. Macrophage activation and polarization: nomenclature and experimental guidelines. Immunity (2014) 41(1):14-20. doi:10.1016/j.immuni.2014.06.008
    • (2014) Immunity , vol.41 , Issue.1 , pp. 14-20
    • Murray, P.J.1    Allen, J.E.2    Biswas, S.K.3    Fisher, E.A.4    Gilroy, D.W.5    Goerdt, S.6
  • 8
    • 84877119701 scopus 로고    scopus 로고
    • Epigenetic regulation of macrophage polarization and function
    • Ivashkiv LB. Epigenetic regulation of macrophage polarization and function. Trends Immunol (2013) 34(5):216-23. doi:10.1016/j.it.2012.11.001
    • (2013) Trends Immunol , vol.34 , Issue.5 , pp. 216-223
    • Ivashkiv, L.B.1
  • 9
    • 84875544506 scopus 로고    scopus 로고
    • Interleukin-4-and interleukin-13-mediated alternatively activated macrophages: roles in homeostasis and disease
    • Van Dyken SJ, Locksley RM. Interleukin-4-and interleukin-13-mediated alternatively activated macrophages: roles in homeostasis and disease. Annu Rev Immunol (2013) 31:317-43. doi:10.1146/annurev-immunol-032712-095906
    • (2013) Annu Rev Immunol , vol.31 , pp. 317-343
    • Van Dyken, S.J.1    Locksley, R.M.2
  • 10
    • 77953268611 scopus 로고    scopus 로고
    • Alternative activation of macrophages: mechanism and functions
    • Gordon S, Martinez FO. Alternative activation of macrophages: mechanism and functions. Immunity (2010) 32(5):593-604. doi:10.1016/j.immuni.2010.05.007
    • (2010) Immunity , vol.32 , Issue.5 , pp. 593-604
    • Gordon, S.1    Martinez, F.O.2
  • 11
    • 84855177782 scopus 로고    scopus 로고
    • Macrophage polarization in health and disease
    • Cassetta L, Cassol E, Poli G. Macrophage polarization in health and disease. ScientificWorldJournal (2011) 11:2391-402. doi:10.1100/2011/213962
    • (2011) ScientificWorldJournal , vol.11 , pp. 2391-2402
    • Cassetta, L.1    Cassol, E.2    Poli, G.3
  • 12
    • 79955746123 scopus 로고    scopus 로고
    • The control of adaptive immune responses by the innate immune system
    • Schenten D, Medzhitov R. The control of adaptive immune responses by the innate immune system. Adv Immunol (2011) 109:87-124. doi:10.1016/B978-0-12-387664-5.00003-0
    • (2011) Adv Immunol , vol.109 , pp. 87-124
    • Schenten, D.1    Medzhitov, R.2
  • 13
    • 84886055095 scopus 로고    scopus 로고
    • Pattern recognition theory and the launch of modern innate immunity
    • Medzhitov R. Pattern recognition theory and the launch of modern innate immunity. J Immunol (2013) 191(9):4473-4. doi:10.4049/jimmunol.1302427
    • (2013) J Immunol , vol.191 , Issue.9 , pp. 4473-4474
    • Medzhitov, R.1
  • 14
    • 75449093273 scopus 로고    scopus 로고
    • TIR-containing adaptors in toll-like receptor signalling
    • Jenkins KA, Mansell A. TIR-containing adaptors in toll-like receptor signalling. Cytokine (2010) 49(3):237-44. doi:10.1016/j.cyto.2009.01.009
    • (2010) Cytokine , vol.49 , Issue.3 , pp. 237-244
    • Jenkins, K.A.1    Mansell, A.2
  • 15
    • 0035727293 scopus 로고    scopus 로고
    • Macrophage arginine metabolism to ornithine/urea or nitric oxide/citrulline: a life or death issue
    • Mills CD. Macrophage arginine metabolism to ornithine/urea or nitric oxide/citrulline: a life or death issue. Crit Rev Immunol (2001) 21(5):399-425. doi:10.1615/CritRevImmunol.v21.i5.10
    • (2001) Crit Rev Immunol , vol.21 , Issue.5 , pp. 399-425
    • Mills, C.D.1
  • 16
    • 84888406185 scopus 로고    scopus 로고
    • Macrophage polarization and function with emphasis on the evolving roles of coordinated regulation of cellular signaling pathways
    • Zhou D, Huang C, Lin Z, Zhan S, Kong L, Fang C, et al. Macrophage polarization and function with emphasis on the evolving roles of coordinated regulation of cellular signaling pathways. Cell Signal (2014) 26(2):192-7. doi:10.1016/j.cellsig.2013.11.004
    • (2014) Cell Signal , vol.26 , Issue.2 , pp. 192-197
    • Zhou, D.1    Huang, C.2    Lin, Z.3    Zhan, S.4    Kong, L.5    Fang, C.6
  • 17
    • 84865335926 scopus 로고    scopus 로고
    • The biology and mechanism of action of suppressor of cytokine signaling 3
    • Babon JJ, Nicola NA. The biology and mechanism of action of suppressor of cytokine signaling 3. Growth Factors (2012) 30(4):207-19. doi:10.3109/08977194.2012.687375
    • (2012) Growth Factors , vol.30 , Issue.4 , pp. 207-219
    • Babon, J.J.1    Nicola, N.A.2
  • 18
    • 84892930737 scopus 로고    scopus 로고
    • Molecular basis of MAP kinase regulation
    • Peti W, Page R. Molecular basis of MAP kinase regulation. Protein Sci (2013) 22(12):1698-710. doi:10.1002/pro.2374
    • (2013) Protein Sci , vol.22 , Issue.12 , pp. 1698-1710
    • Peti, W.1    Page, R.2
  • 19
    • 77954961992 scopus 로고    scopus 로고
    • Macrophages: master regulators of inflammation and fibrosis
    • Wynn TA, Barron L. Macrophages: master regulators of inflammation and fibrosis. Semin Liver Dis (2010) 30(3):245-57. doi:10.1055/s-0030-1255354
    • (2010) Semin Liver Dis , vol.30 , Issue.3 , pp. 245-257
    • Wynn, T.A.1    Barron, L.2
  • 21
    • 44849113635 scopus 로고    scopus 로고
    • Genetic analysis of the role of the PI3K-Akt pathway in lipopolysaccharide-induced cytokine and tissue factor gene expression in monocytes/macrophages
    • Luyendyk JP, Schabbauer GA, Tencati M, Holscher T, Pawlinski R, Mackman N. Genetic analysis of the role of the PI3K-Akt pathway in lipopolysaccharide-induced cytokine and tissue factor gene expression in monocytes/macrophages. J Immunol (2008) 180(6):4218-26. doi:10.4049/jimmunol.180.6.4218
    • (2008) J Immunol , vol.180 , Issue.6 , pp. 4218-4226
    • Luyendyk, J.P.1    Schabbauer, G.A.2    Tencati, M.3    Holscher, T.4    Pawlinski, R.5    Mackman, N.6
  • 24
    • 84880227738 scopus 로고    scopus 로고
    • Akt1-mediated regulation of macrophage polarization in a murine model of Staphylococcus aureus pulmonary infection
    • Xu F, Kang Y, Zhang H, Piao Z, Yin H, Diao R, et al. Akt1-mediated regulation of macrophage polarization in a murine model of Staphylococcus aureus pulmonary infection. J Infect Dis (2013) 208(3):528-38. doi:10.1093/infdis/jit177
    • (2013) J Infect Dis , vol.208 , Issue.3 , pp. 528-538
    • Xu, F.1    Kang, Y.2    Zhang, H.3    Piao, Z.4    Yin, H.5    Diao, R.6
  • 25
    • 0036734498 scopus 로고    scopus 로고
    • Sensitization of IFN-gamma Jak-STAT signaling during macrophage activation
    • Hu X, Herrero C, Li WP, Antoniv TT, Falck-Pedersen E, Koch AE, et al. Sensitization of IFN-gamma Jak-STAT signaling during macrophage activation. Nat Immunol (2002) 3(9):859-66. doi:10.1038/ni828
    • (2002) Nat Immunol , vol.3 , Issue.9 , pp. 859-866
    • Hu, X.1    Herrero, C.2    Li, W.P.3    Antoniv, T.T.4    Falck-Pedersen, E.5    Koch, A.E.6
  • 26
    • 80355146399 scopus 로고    scopus 로고
    • Transcriptional regulation of macrophage polarization: enabling diversity with identity
    • Lawrence T, Natoli G. Transcriptional regulation of macrophage polarization: enabling diversity with identity. Nat Rev Immunol (2011) 11(11):750-61. doi:10.1038/nri3088
    • (2011) Nat Rev Immunol , vol.11 , Issue.11 , pp. 750-761
    • Lawrence, T.1    Natoli, G.2
  • 27
    • 79953678939 scopus 로고    scopus 로고
    • Obstacles and opportunities for understanding macrophage polarization
    • Murray PJ, Wynn TA. Obstacles and opportunities for understanding macrophage polarization. J Leukoc Biol (2011) 89(4):557-63. doi:10.1189/jlb.0710409
    • (2011) J Leukoc Biol , vol.89 , Issue.4 , pp. 557-563
    • Murray, P.J.1    Wynn, T.A.2
  • 28
    • 0018587727 scopus 로고
    • Enhancement of spreading, phagocytosis and chemotaxis by macrophage stimulating protein (MSP)
    • Leonard EJ, Skeel AH. Enhancement of spreading, phagocytosis and chemotaxis by macrophage stimulating protein (MSP). Adv Exp Med Biol (1979) 121B:181-94.
    • (1979) Adv Exp Med Biol , vol.121 B , pp. 181-194
    • Leonard, E.J.1    Skeel, A.H.2
  • 29
    • 0029027666 scopus 로고
    • The murine stk gene product, a transmembrane protein tyrosine kinase, is a receptor for macrophage-stimulating protein
    • Wang MH, Iwama A, Skeel A, Suda T, Leonard EJ. The murine stk gene product, a transmembrane protein tyrosine kinase, is a receptor for macrophage-stimulating protein. Proc Natl Acad Sci U S A (1995) 92(9):3933-7. doi:10.1073/pnas.92.25.11751
    • (1995) Proc Natl Acad Sci U S A , vol.92 , Issue.9 , pp. 3933-3937
    • Wang, M.H.1    Iwama, A.2    Skeel, A.3    Suda, T.4    Leonard, E.J.5
  • 30
    • 80052840444 scopus 로고    scopus 로고
    • Proteolytic activation of pro-macrophage-stimulating protein by hepsin
    • Ganesan R, Kolumam GA, Lin SJ, Xie MH, Santell L, Wu TD, et al. Proteolytic activation of pro-macrophage-stimulating protein by hepsin. Mol Cancer Res (2011) 9(9):1175-86. doi:10.1158/1541-7786.MCR-11-0004
    • (2011) Mol Cancer Res , vol.9 , Issue.9 , pp. 1175-1186
    • Ganesan, R.1    Kolumam, G.A.2    Lin, S.J.3    Xie, M.H.4    Santell, L.5    Wu, T.D.6
  • 31
    • 0031061689 scopus 로고    scopus 로고
    • Deregulated inflammatory response in mice lacking the STK/RON receptor tyrosine kinase
    • Correll PH, Iwama A, Tondat S, Mayrhofer G, Suda T, Bernstein A. Deregulated inflammatory response in mice lacking the STK/RON receptor tyrosine kinase. Genes Funct (1997) 1(1):69-83. doi:10.1046/j.1365-4624.1997.00009.x
    • (1997) Genes Funct , vol.1 , Issue.1 , pp. 69-83
    • Correll, P.H.1    Iwama, A.2    Tondat, S.3    Mayrhofer, G.4    Suda, T.5    Bernstein, A.6
  • 32
    • 0034894020 scopus 로고    scopus 로고
    • RON-mediated cytoplasmic signaling is dispensable for viability but is required to limit inflammatory responses
    • Waltz SE, Eaton L, Toney-Earley K, Hess KA, Peace BE, Ihlendorf JR, et al. RON-mediated cytoplasmic signaling is dispensable for viability but is required to limit inflammatory responses. J Clin Invest (2001) 108(4):567-76. doi:10.1172/JCI200111881
    • (2001) J Clin Invest , vol.108 , Issue.4 , pp. 567-576
    • Waltz, S.E.1    Eaton, L.2    Toney-Earley, K.3    Hess, K.A.4    Peace, B.E.5    Ihlendorf, J.R.6
  • 33
    • 1642443959 scopus 로고    scopus 로고
    • Macrophage-stimulating protein, the ligand for the stem cell-derived tyrosine kinase/RON receptor tyrosine kinase, inhibits IL-12 production by primary peritoneal macrophages stimulated with IFN-gamma and lipopolysaccharide
    • Morrison AC, Wilson CB, Ray M, Correll PH. Macrophage-stimulating protein, the ligand for the stem cell-derived tyrosine kinase/RON receptor tyrosine kinase, inhibits IL-12 production by primary peritoneal macrophages stimulated with IFN-gamma and lipopolysaccharide. J Immunol (2004) 172(3):1825-32. doi:10.4049/jimmunol.172.3.1825
    • (2004) J Immunol , vol.172 , Issue.3 , pp. 1825-1832
    • Morrison, A.C.1    Wilson, C.B.2    Ray, M.3    Correll, P.H.4
  • 34
    • 84881474744 scopus 로고    scopus 로고
    • Host genetic background impacts modulation of the TLR4 pathway by RON in tissue-associated macrophages
    • Chaudhuri A, Wilson NS, Yang B, Paler Martinez A, Liu J, Zhu C, et al. Host genetic background impacts modulation of the TLR4 pathway by RON in tissue-associated macrophages. Immunol Cell Biol (2013) 91(7):451-60. doi:10.1038/icb.2013.27
    • (2013) Immunol Cell Biol , vol.91 , Issue.7 , pp. 451-460
    • Chaudhuri, A.1    Wilson, N.S.2    Yang, B.3    Paler Martinez, A.4    Liu, J.5    Zhu, C.6
  • 35
    • 0032741542 scopus 로고    scopus 로고
    • Negative regulation of macrophage activation in response to IFN-gamma and lipopolysaccharide by the STK/RON receptor tyrosine kinase
    • Liu QP, Fruit K, Ward J, Correll PH. Negative regulation of macrophage activation in response to IFN-gamma and lipopolysaccharide by the STK/RON receptor tyrosine kinase. J Immunol (1999) 163(12):6606-13.
    • (1999) J Immunol , vol.163 , Issue.12 , pp. 6606-6613
    • Liu, Q.P.1    Fruit, K.2    Ward, J.3    Correll, P.H.4
  • 36
    • 0032211131 scopus 로고    scopus 로고
    • Activation of the RON receptor tyrosine kinase inhibits inducible nitric oxide synthase (iNOS) expression by murine peritoneal exudate macrophages: phosphatidylinositol-3 kinase is required for RON-mediated inhibition of iNOS expression
    • Chen YQ, Fisher JH, Wang MH. Activation of the RON receptor tyrosine kinase inhibits inducible nitric oxide synthase (iNOS) expression by murine peritoneal exudate macrophages: phosphatidylinositol-3 kinase is required for RON-mediated inhibition of iNOS expression. J Immunol (1998) 161(9):4950-9.
    • (1998) J Immunol , vol.161 , Issue.9 , pp. 4950-4959
    • Chen, Y.Q.1    Fisher, J.H.2    Wang, M.H.3
  • 37
    • 0037080191 scopus 로고    scopus 로고
    • Activation of the stem cell-derived tyrosine kinase/RON receptor tyrosine kinase by macrophage-stimulating protein results in the induction of arginase activity in murine peritoneal macrophages
    • Morrison AC, Correll PH. Activation of the stem cell-derived tyrosine kinase/RON receptor tyrosine kinase by macrophage-stimulating protein results in the induction of arginase activity in murine peritoneal macrophages. J Immunol (2002) 168(2):853-60. doi:10.4049/jimmunol.168.2.853
    • (2002) J Immunol , vol.168 , Issue.2 , pp. 853-860
    • Morrison, A.C.1    Correll, P.H.2
  • 38
    • 80052657814 scopus 로고    scopus 로고
    • Regulation of macrophage arginase expression and tumor growth by the RON receptor tyrosine kinase
    • Sharda DR, Yu S, Ray M, Squadrito ML, De Palma M, Wynn TA, et al. Regulation of macrophage arginase expression and tumor growth by the RON receptor tyrosine kinase. J Immunol (2011) 187(5):2181-92. doi:10.4049/jimmunol.1003460
    • (2011) J Immunol , vol.187 , Issue.5 , pp. 2181-2192
    • Sharda, D.R.1    Yu, S.2    Ray, M.3    Squadrito, M.L.4    De Palma, M.5    Wynn, T.A.6
  • 39
    • 0034727410 scopus 로고    scopus 로고
    • AIDA reduces glutamate release and attenuates mechanical allodynia after spinal cord injury
    • Mills CD, Xu GY, Johnson KM, McAdoo DJ, Hulsebosch CE. AIDA reduces glutamate release and attenuates mechanical allodynia after spinal cord injury. Neuroreport (2000) 11(14):3067-70. doi:10.1097/00001756-200009280-00007
    • (2000) Neuroreport , vol.11 , Issue.14 , pp. 3067-3070
    • Mills, C.D.1    Xu, G.Y.2    Johnson, K.M.3    McAdoo, D.J.4    Hulsebosch, C.E.5
  • 40
    • 0034659784 scopus 로고    scopus 로고
    • M-1/M-2 macrophages and the Th1/Th2 paradigm
    • Mills CD, Kincaid K, Alt JM, Heilman MJ, Hill AM. M-1/M-2 macrophages and the Th1/Th2 paradigm. J Immunol (2000) 164(12):6166-73. doi:10.4049/jimmunol.164.12.6166
    • (2000) J Immunol , vol.164 , Issue.12 , pp. 6166-6173
    • Mills, C.D.1    Kincaid, K.2    Alt, J.M.3    Heilman, M.J.4    Hill, A.M.5
  • 42
    • 13244287735 scopus 로고    scopus 로고
    • RON tyrosine kinase receptor regulates papilloma growth and malignant conversion in a murine model of skin carcinogenesis
    • Chan EL, Peace BE, Collins MH, Toney-Earley K, Waltz SE. RON tyrosine kinase receptor regulates papilloma growth and malignant conversion in a murine model of skin carcinogenesis. Oncogene (2005) 24(3):479-88. doi:10.1038/sj.onc.1208909
    • (2005) Oncogene , vol.24 , Issue.3 , pp. 479-488
    • Chan, E.L.1    Peace, B.E.2    Collins, M.H.3    Toney-Earley, K.4    Waltz, S.E.5
  • 43
    • 84904406680 scopus 로고    scopus 로고
    • Tumor-associated macrophages: from mechanisms to therapy
    • Noy R, Pollard JW. Tumor-associated macrophages: from mechanisms to therapy. Immunity (2014) 41(1):49-61. doi:10.1016/j.immuni.2014.06.010
    • (2014) Immunity , vol.41 , Issue.1 , pp. 49-61
    • Noy, R.1    Pollard, J.W.2


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