메뉴 건너뛰기




Volumn 305, Issue 4, 2013, Pages

MLK3 promotes metabolic dysfunction induced by saturated fatty acid-enriched diet

Author keywords

Inflammation; Insulin resistance; Mixed lineage kinase 3; Saturated fatty acids

Indexed keywords

ADIPONECTIN; ADRENALIN; ARGINASE; FIBROBLAST GROWTH FACTOR 21; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; LEPTIN; MESSENGER RNA; MIXED LINEAGE KINASE 3; MONOCYTE CHEMOTACTIC PROTEIN 1; PALMITIC ACID; SATURATED FATTY ACID; TUMOR NECROSIS FACTOR ALPHA;

EID: 84881633915     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00197.2013     Document Type: Article
Times cited : (41)

References (46)
  • 1
    • 0034708832 scopus 로고    scopus 로고
    • The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307)
    • Aguirre V, Uchida T, Yenush L, Davis R, White MF. The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307). J Biol Chem 275: 9047-9054, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 9047-9054
    • Aguirre, V.1    Uchida, T.2    Yenush, L.3    Davis, R.4    White, M.F.5
  • 4
    • 0034881391 scopus 로고    scopus 로고
    • The adipocytesecreted protein Acrp30 enhances hepatic insulin action
    • Berg AH, Combs TP, Du X, Brownlee M, Scherer PE. The adipocytesecreted protein Acrp30 enhances hepatic insulin action. Nat Med 7: 947-953, 2001.
    • (2001) Nat Med , vol.7 , pp. 947-953
    • Berg, A.H.1    Combs, T.P.2    Du, X.3    Brownlee, M.4    Scherer, P.E.5
  • 8
    • 0034644522 scopus 로고    scopus 로고
    • Signal transduction by the JNK group of MAP kinases
    • Davis RJ. Signal transduction by the JNK group of MAP kinases. Cell 103: 239-252, 2000.
    • (2000) Cell , vol.103 , pp. 239-252
    • Davis, R.J.1
  • 10
    • 53849086177 scopus 로고    scopus 로고
    • Differential regulation of the ER stress response by long-chain fatty acids in the pancreatic beta-cell
    • Diakogiannaki E, Morgan NG. Differential regulation of the ER stress response by long-chain fatty acids in the pancreatic beta-cell. Biochem Soc Trans 36: 959-962, 2008.
    • (2008) Biochem Soc Trans , vol.36 , pp. 959-962
    • Diakogiannaki, E.1    Morgan, N.G.2
  • 11
    • 84871183282 scopus 로고    scopus 로고
    • Influence of dietary saturated fat content on adiposity, macrophage behavior, inflammation, and metabolism: Composition matters
    • Enos RT, Davis JM, Velazquez KT, McClellan JL, Day SD, Carnevale KA, Murphy EA. Influence of dietary saturated fat content on adiposity, macrophage behavior, inflammation, and metabolism: composition matters. J Lipid Res 54: 152-163, 2013.
    • (2013) J Lipid Res , vol.54 , pp. 152-163
    • Enos, R.T.1    Davis, J.M.2    Velazquez, K.T.3    McClellan, J.L.4    Day, S.D.5    Carnevale, K.A.6    Murphy, E.A.7
  • 12
    • 1842531067 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein 1 expression is stimulated by growth hormone and interleukin-6 in 3T3-L1 adipocytes
    • Fasshauer M, Klein J, Kralisch S, Klier M, Lossner U, Bluher M, Paschke R. Monocyte chemoattractant protein 1 expression is stimulated by growth hormone and interleukin-6 in 3T3-L1 adipocytes. Biochem Biophys Res Commun 317: 598-604, 2004.
    • (2004) Biochem Biophys Res Commun , vol.317 , pp. 598-604
    • Fasshauer, M.1    Klein, J.2    Kralisch, S.3    Klier, M.4    Lossner, U.5    Bluher, M.6    Paschke, R.7
  • 13
    • 35848935201 scopus 로고    scopus 로고
    • Cause-specific excess deaths associated with underweight, overweight, and obesity
    • Flegal KM, Graubard BI, Williamson DF, Gail MH. Cause-specific excess deaths associated with underweight, overweight, and obesity. JAMA 298: 2028-2037, 2007.
    • (2007) JAMA , vol.298 , pp. 2028-2037
    • Flegal, K.M.1    Graubard, B.I.2    Williamson, D.F.3    Gail, M.H.4
  • 14
    • 21544462572 scopus 로고    scopus 로고
    • Risks for all-cause mortality, cardiovascular disease, and diabetes associated with the metabolic syndrome: A summary of the evidence
    • Ford ES. Risks for all-cause mortality, cardiovascular disease, and diabetes associated with the metabolic syndrome: a summary of the evidence. Diabetes Care 28: 1769-1778, 2005.
    • (2005) Diabetes Care , vol.28 , pp. 1769-1778
    • Ford, E.S.1
  • 15
    • 0036731701 scopus 로고    scopus 로고
    • Mixed-lineage kinase control of JNK and p38 MAPK pathways
    • Gallo KA, Johnson GL. Mixed-lineage kinase control of JNK and p38 MAPK pathways. Nat Rev Mol Cell Biol 3: 663-672, 2002.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 663-672
    • Gallo, K.A.1    Johnson, G.L.2
  • 17
    • 84872142459 scopus 로고    scopus 로고
    • JNK expression by macrophages promotes obesity-induced insulin resistance and inflammation
    • Han MS, Jung DY, Morel C, Lakhani SA, Kim JK, Flavell RA, Davis RJ. JNK expression by macrophages promotes obesity-induced insulin resistance and inflammation. Science 339: 218-222, 2013.
    • (2013) Science , vol.339 , pp. 218-222
    • Han, M.S.1    Jung, D.Y.2    Morel, C.3    Lakhani, S.A.4    Kim, J.K.5    Flavell, R.A.6    Davis, R.J.7
  • 19
    • 84855503248 scopus 로고    scopus 로고
    • Longand medium-chain fatty acids induce insulin resistance to a similar extent in humans despite marked differences in muscle fat accumulation
    • Hoeks J, Mensink M, Hesselink MK, Ekroos K, Schrauwen P. Longand medium-chain fatty acids induce insulin resistance to a similar extent in humans despite marked differences in muscle fat accumulation. J Clin Endocrinol Metab 97: 208-216, 2012.
    • (2012) J Clin Endocrinol Metab , vol.97 , pp. 208-216
    • Hoeks, J.1    Mensink, M.2    Hesselink, M.K.3    Ekroos, K.4    Schrauwen, P.5
  • 20
    • 80053554640 scopus 로고    scopus 로고
    • Saturated fatty acids induce c-Src clustering within membrane subdomains, leading to JNK activation
    • Holzer RG, Park EJ, Li N, Tran H, Chen M, Choi C, Solinas G, Karin M. Saturated fatty acids induce c-Src clustering within membrane subdomains, leading to JNK activation. Cell 147: 173-184, 2011.
    • (2011) Cell , vol.147 , pp. 173-184
    • Holzer, R.G.1    Park, E.J.2    Li, N.3    Tran, H.4    Chen, M.5    Choi, C.6    Solinas, G.7    Karin, M.8
  • 21
    • 34547219895 scopus 로고    scopus 로고
    • Metabolic stress signaling mediated by mixedlineage kinases
    • Jaeschke A, Davis RJ. Metabolic stress signaling mediated by mixedlineage kinases. Mol Cell 27: 498-508, 2007.
    • (2007) Mol Cell , vol.27 , pp. 498-508
    • Jaeschke, A.1    Davis, R.J.2
  • 24
    • 0023248851 scopus 로고
    • Differential oxidation of saturated and unsaturated fatty acids in vivo in the rat
    • Leyton J, Drury PJ, Crawford MA. Differential oxidation of saturated and unsaturated fatty acids in vivo in the rat. Br J Nutr 57: 383-393, 1987.
    • (1987) Br J Nutr , vol.57 , pp. 383-393
    • Leyton, J.1    Drury, P.J.2    Crawford, M.A.3
  • 26
    • 33846026712 scopus 로고    scopus 로고
    • Obesity induces a phenotypic switch in adipose tissue macrophage polarization
    • Lumeng CN, Bodzin JL, Saltiel AR. Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J Clin Invest 117: 175-184, 2007.
    • (2007) J Clin Invest , vol.117 , pp. 175-184
    • Lumeng, C.N.1    Bodzin, J.L.2    Saltiel, A.R.3
  • 29
    • 36849005372 scopus 로고    scopus 로고
    • A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways
    • Nguyen MT, Favelyukis S, Nguyen AK, Reichart D, Scott PA, Jenn A, Liu-Bryan R, Glass CK, Neels JG, Olefsky JM. A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways. J Biol Chem 282: 35279-35292, 2007.
    • (2007) J Biol Chem , vol.282 , pp. 35279-35292
    • Nguyen, M.T.1    Favelyukis, S.2    Nguyen, A.K.3    Reichart, D.4    Scott, P.A.5    Jenn, A.6    Liu-Bryan, R.7    Glass, C.K.8    Neels, J.G.9    Olefsky, J.M.10
  • 31
    • 39049131173 scopus 로고    scopus 로고
    • Inflammation, obesity, and fatty acid metabolism: Influence of n-3 polyunsaturated fatty acids on factors contributing to metabolic syndrome
    • Robinson LE, Buchholz AC, Mazurak VC. Inflammation, obesity, and fatty acid metabolism: influence of n-3 polyunsaturated fatty acids on factors contributing to metabolic syndrome. Appl Physiol Nutr Metab 32: 1008-1024, 2007.
    • (2007) Appl Physiol Nutr Metab , vol.32 , pp. 1008-1024
    • Robinson, L.E.1    Buchholz, A.C.2    Mazurak, V.C.3
  • 35
    • 83555162619 scopus 로고    scopus 로고
    • Cdc42 and Rac1 are major contributors to the saturated fatty acid-stimulated JNK pathway in hepatocytes
    • Sharma M, Urano F, Jaeschke A. Cdc42 and Rac1 are major contributors to the saturated fatty acid-stimulated JNK pathway in hepatocytes. J Hepatol 56: 192-198, 2012.
    • (2012) J Hepatol , vol.56 , pp. 192-198
    • Sharma, M.1    Urano, F.2    Jaeschke, A.3
  • 37
    • 33750823407 scopus 로고    scopus 로고
    • Saturated fatty acids inhibit induction of insulin gene transcription by JNK-mediated phosphorylation of insulin-receptor substrates
    • Solinas G, Naugler W, Galimi F, Lee MS, Karin M. Saturated fatty acids inhibit induction of insulin gene transcription by JNK-mediated phosphorylation of insulin-receptor substrates. Proc Natl Acad Sci USA 103: 16454-16459, 2006.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 16454-16459
    • Solinas, G.1    Naugler, W.2    Galimi, F.3    Lee, M.S.4    Karin, M.5
  • 38
    • 0037261355 scopus 로고    scopus 로고
    • Mediumversus long-chain triglycerides for 27 days increases fat oxidation and energy expenditure without resulting in changes in body composition in overweight women
    • St-Onge MP, Bourque C, Jones PJ, Ross R, Parsons WE. Mediumversus long-chain triglycerides for 27 days increases fat oxidation and energy expenditure without resulting in changes in body composition in overweight women. Int J Obes Relat Metab Disord 27: 95-102, 2003.
    • (2003) Int J Obes Relat Metab Disord , vol.27 , pp. 95-102
    • St-Onge, M.P.1    Bourque, C.2    Jones, P.J.3    Ross, R.4    Parsons, W.E.5
  • 39
    • 0038546461 scopus 로고    scopus 로고
    • Medium-chain triglycerides increase energy expenditure and decrease adiposity in overweight men
    • St-Onge MP, Ross R, Parsons WD, Jones PJ. Medium-chain triglycerides increase energy expenditure and decrease adiposity in overweight men. Obes Res 11: 395-402, 2003.
    • (2003) Obes Res , vol.11 , pp. 395-402
    • St-Onge, M.P.1    Ross, R.2    Parsons, W.D.3    Jones, P.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.