Isomeric C12-alkamides from the roots of Echinacea purpurea improve basal and insulin-dependent glucose uptake in 3T3-L1 adipocytes

Planta Medica

Volumn 80, Issue 18, 2014, Pages 1712-1720

  Kotowska, Dorota ^a   El Houri, Rime B ^b   Borkowski, Kamil ^a   Petersen, Rasmus K ^a   Fretté, Xavier C ^b   Wolber, Gerhard ^c   Grevsen, Kai ^d   Christensen, Kathrine B ^b   Christensen, Lars P ^b   Kristiansen, Karsten ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^c FREIE UNIVERSITÄT BERLIN   (Germany)

^d AARHUS UNIVERSITY   (Denmark)

Author keywords

adipocytes; Alkamides; Asteraceae; Echinacea purpurea; Glucose uptake; PPAR partial agonist

Indexed keywords

ANTIDIABETIC AGENT; DICHLOROMETHANE; ECHINACEA PURPUREA EXTRACT; LINOLENIC ACID; PARTIAL AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; AMIDE; GLUCOSE; INSULIN; PLANT EXTRACT;

ADIPOCYTE; ANIMAL CELL; ANTIDIABETIC ACTIVITY; ARTICLE; BINDING ASSAY; ECHINACEA PURPUREA; GLUCOSE TRANSPORT; INSULIN SENSITIVITY; LIPOPHILICITY; MOUSE; NONHUMAN; TRANSACTIVATION ASSAY; 3T3 CELL LINE; AGONISTS; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; ECHINACEA; GENE EXPRESSION REGULATION; GENETICS; MEDICINAL PLANT; METABOLISM; MOLECULAR DOCKING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PLANT ROOT; TRANSPORT AT THE CELLULAR LEVEL;

ASTERACEAE; ECHINACEA PURPUREA;

3T3-L1 CELLS; ANIMALS; BIOLOGICAL TRANSPORT; DOSE-RESPONSE RELATIONSHIP, DRUG; ECHINACEA; GENE EXPRESSION REGULATION; GLUCOSE; HYPOGLYCEMIC AGENTS; INSULIN; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MOLECULAR DOCKING SIMULATION; MOLECULAR STRUCTURE; PLANT EXTRACTS; PLANT ROOTS; PLANTS, MEDICINAL; POLYUNSATURATED ALKAMIDES; PPAR GAMMA;

EID: 84919331135     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0034-1383252     Document Type: Article

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