Otx1 promotes basal dendritic growth and regulates intrinsic electrophysiological and synaptic properties of layer V pyramidal neurons in mouse motor cortex

Neuroscience

Volumn 285, Issue , 2015, Pages 139-154

  Zhang, Y F ^a,b   Liu, L X ^a,b   Cao, H T ^a,b   Ou, L ^a,b   Qu, J ^a,b   Wang, Y ^a,c   Chen, J G ^a,b  

^a EYE HOSPITAL OF WENZHOU MEDICAL UNIVERSITY   (China)

^b State Key Laboratory Cultivation Base and Key Laboratory of Vision Science   (China)

^c TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Basal dendrites; Burst firing pattern; Connecting probability; Excitatory postsynaptic potential; Otx1 mutant; Otx1 overexpression

Indexed keywords

TRANSCRIPTION FACTOR OTX; TRANSCRIPTION FACTOR OTX1; UNCLASSIFIED DRUG; BIOCYTIN; LYSINE; OTX1 PROTEIN, MOUSE;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ELECTROPHYSIOLOGY; CELL ATTACHED PATCH CLAMP; CELL GROWTH; CELL STRUCTURE; CONNECTOME; CONTROLLED STUDY; DENDRITIC CELL; EMBRYO; EXCITATORY POSTSYNAPTIC POTENTIAL; GAIN OF FUNCTION MUTATION; GENE MUTATION; GENE OVEREXPRESSION; HISTOPATHOLOGY; LAYER V PYRAMIDAL CELL; MALE; MOTOR CORTEX; MOUSE; NERVE CELL EXCITABILITY; NONHUMAN; OSCILLATION; OTX1 GENE; PATHOGENESIS; PLASMID; PROBABILITY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PYRAMIDAL NERVE CELL; SEIZURE; SEIZURE THRESHOLD; SYNAPSE; SYNAPTIC DYNAMICS; SYNAPTIC MEMBRANE; ANALOGS AND DERIVATIVES; ANIMAL; C57BL MOUSE; CELL SIZE; CYTOLOGY; DENDRITE; ELECTROPORATION; ELECTROSTIMULATION; GENE TRANSFER; GENETICS; KNOCKOUT MOUSE; METABOLISM; MUTATION; PATCH CLAMP TECHNIQUE; PHYSIOLOGY; TISSUE CULTURE TECHNIQUE;

ACTION POTENTIALS; ANIMALS; CELL SIZE; DENDRITES; ELECTRIC STIMULATION; ELECTROPORATION; EXCITATORY POSTSYNAPTIC POTENTIALS; GENE TRANSFER TECHNIQUES; LYSINE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOTOR CORTEX; MUTATION; OTX TRANSCRIPTION FACTORS; PATCH-CLAMP TECHNIQUES; PYRAMIDAL CELLS; SYNAPSES; TISSUE CULTURE TECHNIQUES;

EID: 84918838395     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2014.11.019     Document Type: Article

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