Geometric and functional organization of cortical circuits

Nature Neuroscience

Volumn 8, Issue 6, 2005, Pages 782-790

  Shepherd, Gordon M G ^a,b   Stepanyants, Armen ^b,c   Bureau, Ingrid ^a,b   Chklovskii, Dmitri ^b   Svoboda, Karel ^a,b  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b Watson School of Biological Sciences   (United States)

^c NORTHEASTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BRAIN CORTEX; BRAIN NERVE CELL; DENDRITE; DENDRITIC SPINE; GEOMETRY; LASER; MORPHOLOGY; NERVE CELL NETWORK; NERVE CELL PLASTICITY; NERVE POTENTIAL; NERVE PROJECTION; PHOTOSTIMULATION; PREDICTION; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; ANIMAL; BRAIN MAPPING; CELL SHAPE; CYTOLOGY; ELECTROSTIMULATION; EXCITATORY POSTSYNAPTIC POTENTIAL; IMAGE CYTOMETRY; NERVE FIBER; NERVE TRACT; ORGAN CULTURE TECHNIQUE; PHYSIOLOGY; RADIATION EXPOSURE; RAT; SOMATOSENSORY CORTEX; SPRAGUE DAWLEY RAT; SYNAPSE; SYNAPTIC TRANSMISSION; ULTRASTRUCTURE; ULTRAVIOLET RADIATION;

BIOCYTIN; DRUG DERIVATIVE; LYSINE;

ANIMALS; AXONS; BRAIN MAPPING; CELL SHAPE; DENDRITES; ELECTRIC STIMULATION; EXCITATORY POSTSYNAPTIC POTENTIALS; IMAGE CYTOMETRY; LASERS; LYSINE; NEURAL PATHWAYS; NEURONAL PLASTICITY; ORGAN CULTURE TECHNIQUES; PHOTIC STIMULATION; PYRAMIDAL CELLS; RATS; RATS, SPRAGUE-DAWLEY; SOMATOSENSORY CORTEX; SYNAPSES; SYNAPTIC TRANSMISSION; ULTRAVIOLET RAYS;

EID: 20544445754     PISSN: 10976256     EISSN: None     Source Type: Journal    
DOI: 10.1038/nn1447     Document Type: Article

References (50)

1. Douglas, R.J. & Martin, K.A.C. Neuronal circuits of the neocortex. Annu. Rev. Neurosci. 27, 419-451 (2004).
2. Uttley, A.M. The probability of neural connexions. Proc. R. Soc. Lond. B 144, 229-240 (1955).
3. White, E.L. Cortical Circuits (Birkhäuser, Boston, 1989).
4. Braitenberg, V.B. & Schüz, A. Cortex: Statistics and Geometry of Neuronal Connectivity (Springer, Berlin, 1998).
5. Peters, A. Thalamic input to the cerebral cortex. Trends Neurosci. 2, 1183-1185 (1979).
6. Ramon y Cajal, S. Sur la structure de l'ecorce cerebrale de quelques mamiferes. Cellule 7, 125-176 (1891).
7. Gilbert, C.D. Microcircuitry of the visual cortex. Annu. Rev. Neurosci. 6, 217-247 (1983).
8. Douglas, R.J. & Martin, K.A.C. A functional microcircuit for cat visual cortex. J. Physiol. (Lond.) 440, 735-769 (1991).
9. Kalisman, N., Silberberg, G. & Markram, H. Deriving physical connectivity from neuronal morphology. Biol. Cybern. 88, 210-218 (2003).
10. Hellwig, B. A quantitative analysis of the local connectivity between pyramidal neurons in layers 2/3 of the rat visual cortex. Biol. Cybern. 82, 111-121 (2000).
11. Binzegger, T., Douglas, R.J. & Martin, K.A.C. A quantitative map of the circuit of cat primary visual cortex. J. Neurosci. 24, 8441-8453 (2004).
12. Petersen, C.C.H. & Sakmann, B. The excitatory neuronal network of rat layer 4 barrel cortex. J. Neurosci. 20, 7579-7586 (2000).
13. Koralek, K.A., Jensen, K.F. & Killackey, H.P. Evidence for two complementary patterns of thalamic input to the rat somatosensory cortex. Brain Res. 463, 346-351 (1988).
14. Chmielowska, J., Carvell, G.E. & Simons, D.J. Spatial organization of thalamocortical and corticothalamic projection systems in the rat Sml barrel cortex. J. Comp. Neurol. 285, 325-338 (1989).
15. Lu, S.M. & Lin, R.C.S. Thalamic afferents of the rat barrel cortex: a light- and electron-microscopic study using Phaseolus vulgaris leucoagglutinin as an anterograde tracer. Somatosens. Mot. Res. 10, 1-16 (1992).
16. Kim, U. & Ebner, F.F. Barrels and septa: separate circuits in rat barrels field cortex. J. Comp. Neurol. 408, 489-505 (1999).
17. Shepherd, G.M.G., Pologruto, T.A. & Svoboda, K. Circuit analysis of experience-dependent plasticity in the developing rat barrel cortex. Neuron 38, 277-289 (2003).
18. Brecht, M., Roth, A. & Sakmann, B. Dynamic receptive fields of reconstructed pyramidal cells in layers 3 and 2 of rat somatosensory barrel cortex. J. Physiol. 553, 243-265 (2003).
19. Callaway, E.M. & Katz, L.C. Photostimulation using caged glutamate reveals functional circuitry in living brain slices. Proc. Natl. Acad. Sci. USA 90, 7661-7665 (1993).
20. Dantzker, J.L. & Callaway, E.M. Laminar sources of synaptic input to cortical inhibitory interneurons and pyramidal neurons. Nat. Neurosci. 3, 701-707 (2000).
21. Bureau, I., Shepherd, G.M.G. & Svoboda, K. Precise development of functional and anatomical columns in the neocortex. Neuron 42, 789-801 (2004).
22. Shepherd, G.M.G. & Svoboda, K. Laminar and columnar organization of ascending excitatory projections to layer 2/3 pyramidal neurons in rat barrel cortex. J. Neurosci. (in the press).
23. Ren, J.Q., Aika, Y., Heizmann, C.W. & Kosaka, T. Quantitative analysis of neurons and glial cells in the rat somatosensory cortex, with special reference to GABAergic neurons and parvalbumin-containing neurons. Exp. Brain Res. 92, 1-14 (1992).
24. Keller, A. & Carlson, G.C. Neonatal whisker clipping alters intracortical, but not thalamocortical projections, in rat barrel cortex. J. Comp. Neurol. 412, 83-94 (1999).
25. Bender, K.J., Rangel, J. & Feldman, D.E. Development of columnar topography in the excitatory layer 4 to layer 2/3 projection in rat barrel cortex. J. Neurosci. 23, 8759-8770 (2003).
26. Lubke, J., Egger, V., Sakmann, B. & Feldmeyer, D. Columnar organization of dendrites and axons of single and synaptically coupled excitatory spiny neurons in layer 4 of the rat barrel cortex. J. Neurosci. 20, 5300-5311 (2000).
27. Petersen, C.C.H. & Sakmann, B. Functionally independent columns of rat somatosensory barrel cortex revealed with voltage-sensitive dye imaging. J. Neurosci. 21, 8435-8446 (2001).
28. Staiger, J.F. et al. Functional diversity of layer IV spiny neurons in rat somatosensory cortex: quantitative morphology of electrophysiologically characterized and biocytin labeled cells. Cereb. Cortex (2004).
29. Gottlieb, J.P. & Keller, A. Intrinsic circuitry and physiological properties of pyramidal neurons in rat barrel cortex. Exp. Brain Res. 115, 47-60 (1997).
30. Manns, I.D., Sakmann, B. & Brecht, M. Sub- and suprathreshold receptive field properties of pyramidal neurones in layers 5Aand 5B of rat somatosensory barrel cortex. J. Physiol. (Lond.) 556, 601-622 (2004).
31. Zhang, Z.W. & Deschênes, M. Intracortical axonal projections of lamina VI cells of the primary somatosensory cortex in the rat: a single-cell labeling study. J. Neurosci. 17, 6365-6379 (1997).
32. Burkhalter, A. Intrinsic connections of rat primary visual cortex: laminar organization of axonal projections. J. Comp. Neurol. 279, 171-186 (1989).
33. Stepanyants, A., Hof, P.R. & Chklovskii, D.B. Geometry and structural plasticity of synaptic connectivity. Neuron 34, 275-288 (2002).
34. Peters, A. & Feldman, M.L. The projection of the lateral geniculate nucleus to area 17 of the rat cerebral cortex. I. General description. J. Neurocytol. 5, 63-84 (1976).
35. Song, S., Sjöström, P.J., Reigl, M., Nelson, S. & Chklovskii, D.B. Highly nonrandom features of synaptic connectivity in local cortical circuits. PLoS Biol. 3, 1-13 (2005).
36. Yoshimura, Y., Dantzker, J.L. & Callaway, E.M. Excitatory cortical neurons form fine-scale functional networks. Nature 433, 868-873 (2005).
37. Kalisman, N., Silberberg, G. & Markram, H. The neocortical microcircuit as a tabula rasa. Proc. Natl. Acad. Sci. USA 102, 880-885 (2005).
38. Gupta, A., Wang, Y. & Markram, H. Organizing principles for a diversity of GABAergic interneurons and synapses in the neocortex. Science 287, 273-278 (2000).
39. Stepanyants, A., Tamas, G. & Chklovskii, D.B. Class-specific features of neuronal wiring. Neuron 43, 251-259 (2004).
40. Yabuta, N.H., Sawatari, A. & Callaway, E.M. Two functional channels from primary visual cortex to dorsal visual cortical areas. Science 292, 297-300 (2001).
41. Schubert, D., Kötter, R., Zilles, K., Luhmann, H.J. & Staiger, J.F. Cell type-specific circuits of cortical layer IV spiny neurons. J. Neurosci. 23, 2961-2970 (2003).
42. Sawatari, A. & Callaway, E.M. Diversity and cell type specificity of local excitatory connections to neurons in layer 3B of monkey primary visual cortex. Neuron 25, 459-471 (2000).
43. Schubert, D. et al. Layer-specific intracolumnar and transcolumnar functional connectivity of layer V pyramidal cells in rat barrel cortex. J. Neurosci. 21, 3580-3592 (2001).
44. Linkenhoker, B.A. & Knudsen, E.I. Incremental training increases the plasticity of the auditory space map in adult barn owls. Nature 419, 293-296 (2002).
45. Kaas, J. & Ebner, F. Intrathalamic connections: a new way to modulate cortical plasticity? Nat. Neurosci. 1, 341-342 (1998).
46. Ichinohe, N., Fujiyama, F., Kaneko, T. & Rockland, K.S. Honeycomb-like mosaic at the border of layers 1 and 2 in the cerebral cortex. J. Neurosci. 23, 1372-1382 (2003).
47. Mountcastle, V.B. Modality and topographic properties of single neurons of cat's somatic sensory cortex. J. Neurophysiol. 20, 408-434 (1957).
48. Trachtenberg, JT. et al. Long-term in vivo imaging of experience-dependent synaptic plasticity in adult cortex. Nature 420, 788-794 (2002).
49. Canepari, M., Nelson, L., Papageorgiou, G., Corrie, J.E. & Ogden, D. Photochemical and pharmacological evaluation of 7-nitroindolinyl-and 4-methoxy-7-nitroindolinyl-amino acids as novel, fast caged neurotransmitters. J. Neurosci. Methods 112, 29-42 (2001).
50. Grace, A.A. & Llinás, R. Morphological artifacts induced in intracellularly stained neurons by dehydration: circumvention using rapid dimethyl sulfoxide clearing. Neuroscience 16, 461-475 (1985).