Frequency and dendritic distribution of autapses established by layer 5 pyramidal neurons in the developing rat neocortex: Comparison with synaptic innervation of adjacent neurons of the same class

Journal of Neuroscience

Volumn 16, Issue 10, 1996, Pages 3209-3218

  Lübke, Joachim ^a   Markram, Henry ^b   Frotscher, Michael ^a   Sakmann, Bert ^b  

^a UNIVERSITY OF FREIBURG   (Germany)

^b MAX PLANCK INSTITUTE FOR MEDICAL RESEARCH   (Germany)

Author keywords

autapses; biocytin; camera lucida reconstruction; layer 5 pyramidal neurons; somatosensory cortex; whole cell patch clamp

Indexed keywords

BIOCYTIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; CONTROLLED STUDY; DENDRITE; DENDRITIC SPINE; ELECTRON MICROSCOPY; INNERVATION; NEOCORTEX; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; SOMATOSENSORY CORTEX; SYNAPTOGENESIS;

EID: 0030007410     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.16-10-03209.1996     Document Type: Article

References (26)

1. Bekkers JM, Stevens CF (1991) Excitatory and inhibitory autaptic currents in isolated hippocampal neurons maintained in cell culture. Proc Natl Acad Sci USA 88:7834-7838.
2. Chagnac-Amitai Y, Luhmann HJ, Prince DA (1990) Burst generating and regular spiking layer 5 pyramidal neurons of rat neocortex have different morphological features. J Comp Neurol 296:598-613.
3. Chan-Palay V (1971) The recurrent collaterals of Purkinje cell axons: a correlated study of rat's cerebellar cortex with electron microscopy and the Golgi-method. Z Anat Entwicklungsgesch 134:200-234.
4. Crain SM (1971) Intracellular recordings suggesting synaptic functions in chick embryo spinal sensory ganglion cell isolated in vitro. Brain Res 26:188-191.
5. DiFiglia M, Pasik P, Pasik T (1976) A Golgi-study of neuronal types in the neostriatum of monkeys. Brain Res 114:245-256.
6. Frotscher M, Zimmer J (1983) Lesion-induced mossy fibers to the molecular layer of the rat fascia dentata: identification of postsynaptic granule cells by the Golgi-EM technique. J Comp Neurol 215:299-311.
7. Furshpan EJ, MacLeish PR, O'Lague PH, Potter DD (1976) Chemical transmission between rat sympathetic neurons and cardiac myocytes developing in microcultures: evidence for cholinergic, adrenergic, and dual-function neurons. Proc Natl Acad Sci USA 73:4225-4229.
8. Furshpan EJ, Landis SC, Matsumoto SG, Potter DD (1986) Synaptic functions in rat sympathetic neurons in microcultures. I. Secretion of norepinephrine and acetylcholine. J Neurosci 6:1061-1079.
9. Held H (1897) Beiträge zur Struktur der Nervenzellen und ihrer Fortsätze. Arch Anat Physiol 2:204-294.
10. Karabelas AB, Purpura DP (1980) Evidence for autapses in the substantia nigra. Brain Res 200:467-473.
11. Kasper EM, Larkman AU, Lübke J, Blakemore C (1994a) Pyramidal neurons in layer 5 of the rat visual cortex. I. Correlation among cell morphology, intrinsic electrophysiological properties, and axon targets. J Comp Neurol 339:459-474
12. Kuffler DP, Nicholls J, Drapeau P (1987) Transmitter localization and vesicle turnover at a serotoninergic synapse between identified leech neurons in culture. J Comp Neurol 256:516-526.
13. Landis SC (1976) Rat sympathetic neurons and cardiac myocytes developing in microcultures: corellation of the fine structure of endings with neurotransmitter function in single neurons. Proc Natl Acad Sci USA 73:4220-4224.
14. Larkman AU, Mason A (1990) Correlation between morphology and electrophysiology of pyramidal neurons in slices of rat visual cortex. I. Establishment of cell classes. J Neurosci 10:1407-1414.
15. Mason A, Larkman AU (1990) Correlation between morphology and electrophysiology of pyramidal neurons in slices of rat visual cortex. J Neurosci 10:1415-1428.
16. Paxinos G, Törk T, Tecott LH, Valentino KL (1991) Atlas of the developing rat brain. San Diego: Academic
17. Preston RJ, Bishop GA, Kitai ST (1980) Medium spiny neurons projection from the rat striatum: an intracellular horseradish peroxidase study. Brain Res 183:253-263.
18. Scheibel ME, Scheibel AB (1971) Inhibition and the Renshaw cell. A structural critique. Brain Behav Evol 4:53-93.
19. Segal MM (1991) Epileptiform activity in microcultures containing one excitatory hippocampal neuron. J Neurophysiol 65:761-770.
20. Segal MM (1994) Endogenous bursts underlie seizure like activity in solitary excitatory hippocampal neurons in microcultures. J Neurophysiol 72:1874-1884.
21. Shi W-X, Rayport S (1994) GABA synapses formed in vitro by local axon collaterals of nucleus accumbens neurons. J Neurosci 14:4548-4560.
22. Shkol'nik-Jarros EG (1971) Neurons and interneuronal connections of the central visual system. New York: Plenum.
23. Stuart GJ, Dodt H-U, Sakmann B (1993) Patch-clamp recordings from the soma and dendrites of neurons in brain slices using infrared video microscopy. Pflügers Arch 423:511-518.
24. Sutula T, Xiao-Xian H, Cavazos J, Scott G (1988) Synaptic reorganization in the hippocampus induced by abnormal functional activity Science 239:1147-1150.
25. Tamas G, Buhl EH, Somogyi P (1995) High degree of self-innervation by GABAergic basket cells in the visual cortex of the cat as revealed in vitro. J Physiol PC31.
26. Van der Loos H, Glaser EM (1976) Autapses in neocortical cerebri: synapses between a pyramidal cell's axon and its own dendrites. Brain Res 48:355-360.