메뉴 건너뛰기




Volumn 14, Issue 1, 2015, Pages 64-74

Wnt/β-catenin signaling pathway in hepatocellular carcinomas cases from Colombia

Author keywords

CTNNB1; HBV infection; HCC; Mutation; Subcellular localization; catenin

Indexed keywords

BETA CATENIN; GENOMIC DNA; GLUTAMIC ACID; GLYCINE; ISOLEUCINE; PROLINE; SERINE; THREONINE; WNT PROTEIN; CTNNB1 PROTEIN, HUMAN;

EID: 84918790873     PISSN: 16652681     EISSN: None     Source Type: Journal    
DOI: 10.1016/s1665-2681(19)30802-6     Document Type: Article
Times cited : (34)

References (50)
  • 2
    • 79959296814 scopus 로고    scopus 로고
    • The global epidemiology of hepatocellular carcinoma: Present and future
    • McGlynn KA, London WT. The global epidemiology of hepatocellular carcinoma: present and future. Clinical Liver Disease 2011; 15: 223-43, vii-x.
    • (2011) Clinical Liver Disease , vol.15
    • McGlynn, K.A.1    London, W.T.2
  • 4
    • 79955599940 scopus 로고    scopus 로고
    • Genetic and epigenetic signatures in human hepatocellular carcinoma: A systematic review
    • Nishida N, Goel A. Genetic and epigenetic signatures in human hepatocellular carcinoma: a systematic review. Currents Genomics 2011; 12: 130-7.
    • (2011) Currents Genomics , vol.12 , pp. 130-137
    • Nishida, N.1    Goel, A.2
  • 6
    • 84861625981 scopus 로고    scopus 로고
    • Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma
    • Guichard C, Amaddeo G, Imbeaud S, Ladeiro Y, Pelletier L, Maad IB, Calderaro J, et al. Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma. Natural Genetics 2012; 44: 694-8.
    • (2012) Natural Genetics , vol.44 , pp. 694-698
    • Guichard, C.1    Amaddeo, G.2    Imbeaud, S.3    Ladeiro, Y.4    Pelletier, L.5    Maad, I.B.6    Calderaro, J.7
  • 7
    • 41549115361 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling: New (and old) players and new insights
    • Huang H, He X. Wnt/beta-catenin signaling: new (and old) players and new insights. Current Opinion in Cell Biology 2008; 20: 119-25.
    • (2008) Current Opinion in Cell Biology , vol.20 , pp. 119-125
    • Huang, H.1    He, X.2
  • 8
    • 33746808398 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling in development and disease
    • Clevers H. Wnt/beta-catenin signaling in development and disease. Cell 2006; 127: 469-80.
    • (2006) Cell , vol.127 , pp. 469-480
    • Clevers, H.1
  • 9
    • 23144442645 scopus 로고    scopus 로고
    • Regulation of cadherin-mediated adhesion in morphogenesis
    • Gumbiner BM. Regulation of cadherin-mediated adhesion in morphogenesis. Natural Reviews Molecular Cell Biology 2005; 6: 622-34.
    • (2005) Natural Reviews Molecular Cell Biology , vol.6 , pp. 622-634
    • Gumbiner, B.M.1
  • 11
    • 41549133557 scopus 로고    scopus 로고
    • Nuclear Dvl, c- Jun, beta-catenin, and TCF form a complex leading to stabilization of beta-catenin-TCF interaction
    • Gan XQ, Wang JY, Xi Y, Wu ZL, Li YP, Li L. Nuclear Dvl, c- Jun, beta-catenin, and TCF form a complex leading to stabilization of beta-catenin-TCF interaction. J Cell Biol 2008; 180: 1087-100.
    • (2008) J Cell Biol , vol.180 , pp. 1087-1100
    • Gan, X.Q.1    Wang, J.Y.2    Xi, Y.3    Wu, Z.L.4    Li, Y.P.5    Li, L.6
  • 12
    • 36348991571 scopus 로고    scopus 로고
    • Activation of hepatic stem cell marker EpCAM by Wnt-beta-catenin signaling in hepatocellular carcinoma
    • Yamashita T, Budhu A, Forgues M, Wang XW. Activation of hepatic stem cell marker EpCAM by Wnt-beta-catenin signaling in hepatocellular carcinoma. Can Res J 2007; 67(22): 10831-9.
    • (2007) Can Res J , vol.67 , Issue.22 , pp. 10831-10839
    • Yamashita, T.1    Budhu, A.2    Forgues, M.3    Wang, X.W.4
  • 14
    • 42049087606 scopus 로고    scopus 로고
    • Correlation between beta-catenin mutations and expression of Wnt-signaling target genes in hepatocellular carcinoma
    • Austinat M, Dunsch R, Wittekind C, Tannapfel A, Gebhardt R, Gaunitz F. Correlation between beta-catenin mutations and expression of Wnt-signaling target genes in hepatocellular carcinoma. Molecular Cancer 2008; 7: 21.
    • (2008) Molecular Cancer , vol.7 , pp. 21
    • Austinat, M.1    Dunsch, R.2    Wittekind, C.3    Tannapfel, A.4    Gebhardt, R.5    Gaunitz, F.6
  • 15
    • 0142028054 scopus 로고    scopus 로고
    • GSK-3beta phosphorylation and alteration of beta-catenin in hepatocellular carcinoma
    • Ban KC, Singh H, Krishnan R, Seow HF. GSK-3beta phosphorylation and alteration of beta-catenin in hepatocellular carcinoma. Cancer Letter 2003; 199: 201-8.
    • (2003) Cancer Letter , vol.199 , pp. 201-208
    • Ban, K.C.1    Singh, H.2    Krishnan, R.3    Seow, H.F.4
  • 16
    • 34248674146 scopus 로고    scopus 로고
    • WNT/beta-catenin signaling in liver health and disease
    • Thompson MD, Monga SP. WNT/beta-catenin signaling in liver health and disease. Hepatology 2007; 45: 1298-305.
    • (2007) Hepatology , vol.45 , pp. 1298-1305
    • Thompson, M.D.1    Monga, S.P.2
  • 17
    • 33846846541 scopus 로고    scopus 로고
    • Differential effects of inactivated Axin1 and activated beta-catenin mutations in human hepatocellular carcinomas
    • Zucman-Rossi J, Benhamouche S, Godard C, Boyault S, Grimber G, Balabud C, Cunha AS, et al. Differential effects of inactivated Axin1 and activated beta-catenin mutations in human hepatocellular carcinomas. Oncogene 2007; 26: 774-80.
    • (2007) Oncogene , vol.26 , pp. 774-780
    • Zucman-Rossi, J.1    Benhamouche, S.2    Godard, C.3    Boyault, S.4    Grimber, G.5    Balabud, C.6    Cunha, A.S.7
  • 20
    • 43049168956 scopus 로고    scopus 로고
    • Ser-249 TP53 and CTNNB1 mutations in circulating free DNA of Egyptian patients with hepatocellular carcinoma versus chronic liver diseases
    • Hosny G, Farahat N, Tayel H, Hainaut P. Ser-249 TP53 and CTNNB1 mutations in circulating free DNA of Egyptian patients with hepatocellular carcinoma versus chronic liver diseases. Cancer Letter 2008; 264: 201-8.
    • (2008) Cancer Letter , vol.264 , pp. 201-208
    • Hosny, G.1    Farahat, N.2    Tayel, H.3    Hainaut, P.4
  • 21
    • 0035793042 scopus 로고    scopus 로고
    • Model-based analysis of oligonucleotide arrays: Expression index computation and outlier detection
    • Li C, Wong W. Model-based analysis of oligonucleotide arrays: Expression index computation and outlier detection. Proceedings of the Nationall Academy of Science USA 2001; 98: 31-6.
    • (2001) Proceedings of the Nationall Academy of Science USA , vol.98 , pp. 31-36
    • Li, C.1    Wong, W.2
  • 22
    • 34248674146 scopus 로고    scopus 로고
    • WNT/beta-catenin signaling in liver health and disease
    • Thompson MD, Monga SP. WNT/beta-catenin signaling in liver health and disease. Hepatology 2007; 45(5): 1298-305.
    • (2007) Hepatology , vol.45 , Issue.5 , pp. 1298-1305
    • Thompson, M.D.1    Monga, S.P.2
  • 24
    • 0037130449 scopus 로고    scopus 로고
    • Mutational spectrum of betacatenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas
    • Taniguchi K, Roberts LR, Aderca IN, Dong X, Qian C, Murphy LM, Nagorney DM, et al. Mutational spectrum of betacatenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas. Oncogene 2002; 21: 4863-71.
    • (2002) Oncogene , vol.21 , pp. 4863-4871
    • Taniguchi, K.1    Roberts, L.R.2    Aderca, I.N.3    Dong, X.4    Qian, C.5    Murphy, L.M.6    Nagorney, D.M.7
  • 25
    • 33748921022 scopus 로고    scopus 로고
    • Genetic inactivation of the APC gene contributes to the malignant progression of sporadic hepatocellular carcinoma: A case report
    • Katoh H, Shibata T, Kokubu A, Ojima H, Kosuge T, Kanai Y, Hiroshashi S. Genetic inactivation of the APC gene contributes to the malignant progression of sporadic hepatocellular carcinoma: a case report. Genes Chromosomes Cancer 2006; 45: 1050-7.
    • (2006) Genes Chromosomes Cancer , vol.45 , pp. 1050-1057
    • Katoh, H.1    Shibata, T.2    Kokubu, A.3    Ojima, H.4    Kosuge, T.5    Kanai, Y.6    Hiroshashi, S.7
  • 27
    • 57249103576 scopus 로고    scopus 로고
    • Epigenetic changes induced by reactive oxygen species in hepatocellular carcinoma: Methylation of the E-cadherin promoter
    • Lim SO, Gu JM, Kim MS, Park CK, Cho JW, Park YM, Jung G. Epigenetic changes induced by reactive oxygen species in hepatocellular carcinoma: methylation of the E-cadherin promoter. Gastroenterology 2008; 135: 2128-40.
    • (2008) Gastroenterology , vol.135 , pp. 2128-2140
    • Lim, S.O.1    Gu, J.M.2    Kim, M.S.3    Park, C.K.4    Cho, J.W.5    Park, Y.M.6    Jung, G.7
  • 32
    • 0742324050 scopus 로고    scopus 로고
    • Alterations of beta-catenin and Tcf-4 instead of GSK-3beta contribute to activation of Wnt pathway in hepatocellular carcinoma
    • Cui J, Zhou X, Liu Y, Tang Z, Romeih M. Alterations of beta-catenin and Tcf-4 instead of GSK-3beta contribute to activation of Wnt pathway in hepatocellular carcinoma. Chinese Medical Journal (Engl) 2003; 116: 1885-92.
    • (2003) Chinese Medical Journal (Engl) , vol.116 , pp. 1885-1892
    • Cui, J.1    Zhou, X.2    Liu, Y.3    Tang, Z.4    Romeih, M.5
  • 33
    • 0034495080 scopus 로고    scopus 로고
    • Betacatenin mutations are associated with a subset of lowstage hepatocellular carcinoma negative for hepatitis B virus and with favorable prognosis
    • Hsu HC, Jeng YM, Mao TL, Chu JS, Lai PL, Peng SY. Betacatenin mutations are associated with a subset of lowstage hepatocellular carcinoma negative for hepatitis B virus and with favorable prognosis. Am J Pathol 2000; 157: 763-70.
    • (2000) Am J Pathol , vol.157 , pp. 763-770
    • Hsu, H.C.1    Jeng, Y.M.2    Mao, T.L.3    Chu, J.S.4    Lai, P.L.5    Peng, S.Y.6
  • 35
    • 84880935149 scopus 로고    scopus 로고
    • Mutations in TP53, CTNNB1 and PIK3CA genes in hepatocellular carcinoma associated with hepatitis B and hepatitis C virus infections
    • Tornesello ML, Buonaguro L, Tatangelo F, Botti G, Izzo F, Buonaguro FM. Mutations in TP53, CTNNB1 and PIK3CA genes in hepatocellular carcinoma associated with hepatitis B and hepatitis C virus infections. Genomics 2013; 102: 74-83.
    • (2013) Genomics , vol.102 , pp. 74-83
    • Tornesello, M.L.1    Buonaguro, L.2    Tatangelo, F.3    Botti, G.4    Izzo, F.5    Buonaguro, F.M.6
  • 36
    • 42649093158 scopus 로고    scopus 로고
    • Large-scale analysis of the genetic and epigenetic alterations in hepatocellular carcinoma from Southeast China
    • Su H, Zhao J, Xiong Y, Xu T, Zhou F, Yuan Y, Zhang Y, et al. Large-scale analysis of the genetic and epigenetic alterations in hepatocellular carcinoma from Southeast China. Mutation Research 2008; 641: 27-35.
    • (2008) Mutation Research , vol.641 , pp. 27-35
    • Su, H.1    Zhao, J.2    Xiong, Y.3    Xu, T.4    Zhou, F.5    Yuan, Y.6    Zhang, Y.7
  • 37
    • 0035395236 scopus 로고    scopus 로고
    • Beta-catenin mutation and overexpression in hepatocellular carcinoma: Clinicopathologic and prognostic significance
    • Wong CM, Fan ST, Ng IO. Beta-catenin mutation and overexpression in hepatocellular carcinoma: clinicopathologic and prognostic significance. Cancer 2001; 92: 136-45.
    • (2001) Cancer , vol.92 , pp. 136-145
    • Wong, C.M.1    Fan, S.T.2    Ng, I.O.3
  • 38
    • 0034953664 scopus 로고    scopus 로고
    • CTNNB1 mutations and beta-catenin protein accumulation in human hepatocellular carcinomas associated with high exposure to aflatoxin B1
    • Devereux TR, Stern MC, Flake GP, Yu MC, Zhang ZQ, London SJ, Taylor SA. CTNNB1 mutations and beta-catenin protein accumulation in human hepatocellular carcinomas associated with high exposure to aflatoxin B1. Molecular Carcinogenesis 2001; 31: 68-73.
    • (2001) Molecular Carcinogenesis , vol.31 , pp. 68-73
    • Devereux, T.R.1    Stern, M.C.2    Flake, G.P.3    Yu, M.C.4    Zhang, Z.Q.5    London, S.J.6    Taylor, S.A.7
  • 39
    • 14544270262 scopus 로고    scopus 로고
    • Mutations of beta-catenin and AXIN I genes are a late event in human hepatocellular carcinogenesis
    • Park JY, Park WS, Nam SW, Kim SY, Lee SH, Yoo NJ, Lee YJ, et al. Mutations of beta-catenin and AXIN I genes are a late event in human hepatocellular carcinogenesis. Liver International 2005; 25: 70-6.
    • (2005) Liver International , vol.25 , pp. 70-76
    • Park, J.Y.1    Park, W.S.2    Nam, S.W.3    Kim, S.Y.4    Lee, S.H.5    Yoo, N.J.6    Lee, Y.J.7
  • 41
    • 0034995765 scopus 로고    scopus 로고
    • Genetic alterations associated with hepatocellular carcinomas define distinct pathways of hepatocarcinogenesis
    • Laurent-Puig P, Legoix P, Bluteau O, Belquiti J, Franco D, Binot F, Monges G, et al. Genetic alterations associated with hepatocellular carcinomas define distinct pathways of hepatocarcinogenesis. Gastroenterology 2001; 120: 1763-73.
    • (2001) Gastroenterology , vol.120 , pp. 1763-1773
    • Laurent-Puig, P.1    Legoix, P.2    Bluteau, O.3    Belquiti, J.4    Franco, D.5    Binot, F.6    Monges, G.7
  • 42
    • 6944250147 scopus 로고    scopus 로고
    • Immunohistochemical analysis and mutational analyses of beta-catenin, Axin family and APC genes in hepatocellular carcinomas
    • Ishizaki Y, Ikeda S, Fujimori M, Shimizu Y, Kurihara T, Itamoto T, Kikuchi A, et al. Immunohistochemical analysis and mutational analyses of beta-catenin, Axin family and APC genes in hepatocellular carcinomas. International Journal Oncology 2004; 24: 1077-83.
    • (2004) International Journal Oncology , vol.24 , pp. 1077-1083
    • Ishizaki, Y.1    Ikeda, S.2    Fujimori, M.3    Shimizu, Y.4    Kurihara, T.5    Itamoto, T.6    Kikuchi, A.7
  • 43
    • 0038505659 scopus 로고    scopus 로고
    • Alterations of RB1, p53 and Wnt pathways in hepatocellular carcinomas associated with hepatitis C, hepatitis B and alcoholic liver cirrhosis
    • Edamoto Y, Hara A, Biernat W, Terracciano L, Cathomas G, Riehle HM, Matsuda M, Fujii H, et al. Alterations of RB1, p53 and Wnt pathways in hepatocellular carcinomas associated with hepatitis C, hepatitis B and alcoholic liver cirrhosis. International Journal of Cancer 2003; 106: 334-41.
    • (2003) International Journal of Cancer , vol.106 , pp. 334-341
    • Edamoto, Y.1    Hara, A.2    Biernat, W.3    Terracciano, L.4    Cathomas, G.5    Riehle, H.M.6    Matsuda, M.7    Fujii, H.8
  • 44
    • 0032761853 scopus 로고    scopus 로고
    • Beta-catenin mutations are frequent in human hepatocellular carcinomas associated with hepatitis C virus infection
    • Huang H, Fujii H, Sankila A, Mahler-Araujo BM, Matsuda M, Cathomas G, Ohgaki H. Beta-catenin mutations are frequent in human hepatocellular carcinomas associated with hepatitis C virus infection. Am J Pathol 1999; 155: 1795-1801.
    • (1999) Am J Pathol , vol.155 , pp. 1795-1801
    • Huang, H.1    Fujii, H.2    Sankila, A.3    Mahler-Araujo, B.M.4    Matsuda, M.5    Cathomas, G.6    Ohgaki, H.7
  • 45
    • 81155125694 scopus 로고    scopus 로고
    • Enhancement of canonical Wnt//-catenin signaling activity by HCV core protein promotes cell growth of hepatocellular carcinoma cells
    • Liu J, Ding X, Tang J, Cao Y, Peng Hu, Zhou F, Shan X, et al. Enhancement of canonical Wnt//-catenin signaling activity by HCV core protein promotes cell growth of hepatocellular carcinoma cells. PLoS One 2011; 6: e27496. doi: 10.1371/journal.pone.0027496
    • (2011) PLoS One , vol.6
    • Liu, J.1    Ding, X.2    Tang, J.3    Cao, Y.4    Hu, P.5    Zhou, F.6    Shan, X.7
  • 46
    • 84868192318 scopus 로고    scopus 로고
    • Hepatitis C virus-induced up-regulation of microRNA-155 promotes hepatocarcinogenesis by activating Wnt signaling
    • Zhang Y, Wei W, Cheng N, Wang K, Li B, Jiang X, Sun S. Hepatitis C virus-induced up-regulation of microRNA-155 promotes hepatocarcinogenesis by activating Wnt signaling. Hepatology 2012; 56: 1631-40.
    • (2012) Hepatology , vol.56 , pp. 1631-1640
    • Zhang, Y.1    Wei, W.2    Cheng, N.3    Wang, K.4    Li, B.5    Jiang, X.6    Sun, S.7
  • 48
    • 84901029835 scopus 로고    scopus 로고
    • Epigenetic silencing of SFRP1 and SFRP5 by hepatitis B virus X protein enhances hepatoma cell tumorigenicity through Wnt signaling pathway
    • Xie Q, Chen L, Shan X, Shan X, Tang J, Zhou F, Chen Q, et al. Epigenetic silencing of SFRP1 and SFRP5 by hepatitis B virus X protein enhances hepatoma cell tumorigenicity through Wnt signaling pathway. International Journal of Cancer 2014; 135: 635-46.
    • (2014) International Journal of Cancer , vol.135 , pp. 635-646
    • Xie, Q.1    Chen, L.2    Shan, X.3    Shan, X.4    Tang, J.5    Zhou, F.6    Chen, Q.7
  • 49
    • 78649636204 scopus 로고    scopus 로고
    • Hepatitis B viral X protein interacts with tumor suppressor adenomatous polyposis coli to activate Wnt//-catenin signaling
    • Hsieh A, Kim HS, Lim SO, Yu DY, Jung G. Hepatitis B viral X protein interacts with tumor suppressor adenomatous polyposis coli to activate Wnt//-catenin signaling. Cancer Letter 2011; 300: 162-72.
    • (2011) Cancer Letter , vol.300 , pp. 162-172
    • Hsieh, A.1    Kim, H.S.2    Lim, S.O.3    Yu, D.Y.4    Jung, G.5
  • 50
    • 84890857725 scopus 로고    scopus 로고
    • N-Catenin signaling in hepatocellular cancer: Implications in inflammation, fibrosis, and proliferation
    • Lee JM, Yang J, Newell P, Singh S, Parwani A, Friedman SL, Nejak-Bowen KN, et al. N-Catenin signaling in hepatocellular cancer: Implications in inflammation, fibrosis, and proliferation. Cancer Letter 2014; 343: 90-7.
    • (2014) Cancer Letter , vol.343 , pp. 90-97
    • Lee, J.M.1    Yang, J.2    Newell, P.3    Singh, S.4    Parwani, A.5    Friedman, S.L.6    Nejak-Bowen, K.N.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.