Epigenetic silencing of SFRP1 and SFRP5 by hepatitis B virus X protein enhances hepatoma cell tumorigenicity through Wnt signaling pathway

International Journal of Cancer

Volumn 135, Issue 3, 2014, Pages 635-646

  Xie, Qing ^a   Chen, Linlin ^a   Shan, Xuefeng ^b   Shan, Xiaoliang ^a   Tang, Jia ^a   Zhou, Fan ^a   Chen, Qingmei ^a   Quan, Huiqin ^a   Nie, Dan ^a   Zhang, Wenlu ^a   Huang, Ai Long ^a   Tang, Ni ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

Epigenetic silencing, SFRPs; Hepatitis B virus; Hepatocellular carcinoma; Wnt catenin signaling pathway

Indexed keywords

DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3A; HEPATITIS B VIRUS X PROTEIN; SECRETED FRIZZLED RELATED PROTEIN 1; SECRETED FRIZZLED RELATED PROTEIN 5; WNT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ACTIVITY; EPIGENETICS; GENE FUNCTION; GENE IDENTIFICATION; GENE SILENCING; HUMAN; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; MALE; MOLECULAR DYNAMICS; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SRFP1 GENE; SRFP5 GENE; TUMOR DIFFERENTIATION;

EPIGENETIC SILENCING, SFRPS; HEPATITIS B VIRUS; HEPATOCELLULAR CARCINOMA; WNT/Β-CATENIN SIGNALING PATHWAY;

BLOTTING, WESTERN; CARCINOMA, HEPATOCELLULAR; CELL MOVEMENT; CHROMATIN IMMUNOPRECIPITATION; DNA METHYLATION; EPIGENESIS, GENETIC; EPITHELIAL-MESENCHYMAL TRANSITION; EYE PROTEINS; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; HEPATITIS B; HEPATITIS B VIRUS; HUMANS; IMMUNOENZYME TECHNIQUES; IMMUNOPRECIPITATION; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LIVER; LIVER NEOPLASMS; MEMBRANE PROTEINS; PROMOTER REGIONS, GENETIC; REAL-TIME POLYMERASE CHAIN REACTION; TRANS-ACTIVATORS; TUMOR CELLS, CULTURED; WNT SIGNALING PATHWAY;

EID: 84901029835     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.28697     Document Type: Article

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