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Volumn 300, Issue 2, 2011, Pages 162-172

Hepatitis B viral X protein interacts with tumor suppressor adenomatous polyposis coli to activate Wnt/β-catenin signaling

Author keywords

Catenin; Adenomatous polyposis coli; Hepatitis B viral X protein; Hepatitis B virus; Hepatocellular carcinoma; Wnt

Indexed keywords

BETA CATENIN; CURCUMIN; MYC PROTEIN; PROTEIN X; QUERCETIN; UVOMORULIN; VIRUS PROTEIN; WNT PROTEIN;

EID: 78649636204     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2010.09.018     Document Type: Article
Times cited : (111)

References (40)
  • 1
    • 33747830764 scopus 로고    scopus 로고
    • Hepatocellular carcinoma pathogenesis: from genes to environment
    • Farazi P.A., DePinho R.A. Hepatocellular carcinoma pathogenesis: from genes to environment. Nat. Rev. Cancer 2006, 6:674-687.
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 674-687
    • Farazi, P.A.1    DePinho, R.A.2
  • 3
    • 0033646209 scopus 로고    scopus 로고
    • Results of surgical and nonsurgical treatment for small-sized hepatocellular carcinomas: a retrospective and nationwide survey in Japan. the liver cancer study group of Japan
    • Arii S., Yamaoka Y., Futagawa S., Inoue K., Kobayashi K., Kojiro M., Makuuchi M., Nakamura Y., Okita K., Yamada R. Results of surgical and nonsurgical treatment for small-sized hepatocellular carcinomas: a retrospective and nationwide survey in Japan. the liver cancer study group of Japan. Hepatology 2000, 32:1224-1229.
    • (2000) Hepatology , vol.32 , pp. 1224-1229
    • Arii, S.1    Yamaoka, Y.2    Futagawa, S.3    Inoue, K.4    Kobayashi, K.5    Kojiro, M.6    Makuuchi, M.7    Nakamura, Y.8    Okita, K.9    Yamada, R.10
  • 4
    • 58149299317 scopus 로고    scopus 로고
    • Molecularly targeted therapy for hepatocellular carcinoma
    • Tanaka S., Arii S. Molecularly targeted therapy for hepatocellular carcinoma. Cancer Sci. 2009, 100:1-8.
    • (2009) Cancer Sci. , vol.100 , pp. 1-8
    • Tanaka, S.1    Arii, S.2
  • 5
    • 77956627711 scopus 로고    scopus 로고
    • The role of signaling pathways in the development and treatment of hepatocellular carcinoma
    • Whittaker S., Marais R., Zhu A.X. The role of signaling pathways in the development and treatment of hepatocellular carcinoma. Oncogene 2010, 29:4989-5005.
    • (2010) Oncogene , vol.29 , pp. 4989-5005
    • Whittaker, S.1    Marais, R.2    Zhu, A.X.3
  • 8
    • 46049093989 scopus 로고    scopus 로고
    • Hepatitis B virus-cell interactions and pathogenesis
    • Nguyen D.H., Ludgate L., Hu J. Hepatitis B virus-cell interactions and pathogenesis. J. Cell Physiol. 2008, 216:289-294.
    • (2008) J. Cell Physiol. , vol.216 , pp. 289-294
    • Nguyen, D.H.1    Ludgate, L.2    Hu, J.3
  • 9
    • 33748288087 scopus 로고    scopus 로고
    • Molecular functions and biological roles of hepatitis B virus x protein
    • Tang H., Oishi N., Kaneko S., Murakami S. Molecular functions and biological roles of hepatitis B virus x protein. Cancer Sci. 2006, 97:977-983.
    • (2006) Cancer Sci. , vol.97 , pp. 977-983
    • Tang, H.1    Oishi, N.2    Kaneko, S.3    Murakami, S.4
  • 10
    • 0034805371 scopus 로고    scopus 로고
    • Through induction of juxtaposition and tyrosine kinase activity of Jak1, X-gene product of hepatitis B virus stimulates Ras and the transcriptional activation through AP-1, NF-kappaB, and SRE enhancers
    • Kim H., Lee Y.H., Won J., Yun Y. Through induction of juxtaposition and tyrosine kinase activity of Jak1, X-gene product of hepatitis B virus stimulates Ras and the transcriptional activation through AP-1, NF-kappaB, and SRE enhancers. Biochem. Biophys. Res. Commun. 2001, 286:886-894.
    • (2001) Biochem. Biophys. Res. Commun. , vol.286 , pp. 886-894
    • Kim, H.1    Lee, Y.H.2    Won, J.3    Yun, Y.4
  • 11
    • 51149118892 scopus 로고    scopus 로고
    • Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of beta-catenin in mice
    • Grigoryan T., Wend P., Klaus A., Birchmeier W. Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of beta-catenin in mice. Genes Dev. 2008, 22:2308-2341.
    • (2008) Genes Dev. , vol.22 , pp. 2308-2341
    • Grigoryan, T.1    Wend, P.2    Klaus, A.3    Birchmeier, W.4
  • 12
    • 33746808398 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling in development and disease
    • Clevers H. Wnt/beta-catenin signaling in development and disease. Cell 2006, 127:469-480.
    • (2006) Cell , vol.127 , pp. 469-480
    • Clevers, H.1
  • 13
    • 0031436939 scopus 로고    scopus 로고
    • Induction of a beta-catenin-LEF-1 complex by wnt-1 and transforming mutants of beta-catenin
    • Porfiri E., Rubinfeld B., Albert I., Hovanes K., Waterman M., Polakis P. Induction of a beta-catenin-LEF-1 complex by wnt-1 and transforming mutants of beta-catenin. Oncogene 1997, 15:2833-2839.
    • (1997) Oncogene , vol.15 , pp. 2833-2839
    • Porfiri, E.1    Rubinfeld, B.2    Albert, I.3    Hovanes, K.4    Waterman, M.5    Polakis, P.6
  • 14
  • 17
    • 0036224749 scopus 로고    scopus 로고
    • The APC gene in colorectal cancer
    • Fodde R. The APC gene in colorectal cancer. Eur. J. Cancer 2002, 38:867-871.
    • (2002) Eur. J. Cancer , vol.38 , pp. 867-871
    • Fodde, R.1
  • 18
    • 35648988947 scopus 로고    scopus 로고
    • Adenomatous polyposis coli (APC): a multi-functional tumor suppressor gene
    • Aoki K., Taketo M.M. Adenomatous polyposis coli (APC): a multi-functional tumor suppressor gene. J. Cell Sci. 2007, 120:3327-3335.
    • (2007) J. Cell Sci. , vol.120 , pp. 3327-3335
    • Aoki, K.1    Taketo, M.M.2
  • 19
    • 0036379830 scopus 로고    scopus 로고
    • Beta-catenin expression in hepatocellular carcinoma: a possible participation of beta-catenin in the dedifferentiation process
    • Suzuki T., Yano H., Nakashima Y., Nakashima O., Kojiro M. Beta-catenin expression in hepatocellular carcinoma: a possible participation of beta-catenin in the dedifferentiation process. J. Gastroenterol. Hepatol. 2002, 17:994-1000.
    • (2002) J. Gastroenterol. Hepatol. , vol.17 , pp. 994-1000
    • Suzuki, T.1    Yano, H.2    Nakashima, Y.3    Nakashima, O.4    Kojiro, M.5
  • 21
    • 2542546650 scopus 로고    scopus 로고
    • Hepatitis B virus X protein is essential for the activation of Wnt/beta-catenin signaling in hepatoma cells
    • Cha M.Y., Kim C.M., Park Y.M., Ryu W.S. Hepatitis B virus X protein is essential for the activation of Wnt/beta-catenin signaling in hepatoma cells. Hepatology 2004, 39:1683-1693.
    • (2004) Hepatology , vol.39 , pp. 1683-1693
    • Cha, M.Y.1    Kim, C.M.2    Park, Y.M.3    Ryu, W.S.4
  • 23
    • 34547600513 scopus 로고    scopus 로고
    • Hepatitis B virus X protein differentially affects the ubiquitin-mediated proteasomal degradation of beta-catenin depending on the status of cellular p53
    • Jung J.K., Kwun H.J., Lee J.O., Arora P., Jang K.L. Hepatitis B virus X protein differentially affects the ubiquitin-mediated proteasomal degradation of beta-catenin depending on the status of cellular p53. J. Gen. Virol. 2007, 88:2144-2154.
    • (2007) J. Gen. Virol. , vol.88 , pp. 2144-2154
    • Jung, J.K.1    Kwun, H.J.2    Lee, J.O.3    Arora, P.4    Jang, K.L.5
  • 24
    • 41049111566 scopus 로고    scopus 로고
    • HBx modulates iron regulatory protein 1-mediated iron metabolism via reactive oxygen species
    • Gu J.M., Lim S.O., Oh S.J., Yoon S.M., Seong J.K., Jung G. HBx modulates iron regulatory protein 1-mediated iron metabolism via reactive oxygen species. Virus Res. 2008, 133:167-177.
    • (2008) Virus Res. , vol.133 , pp. 167-177
    • Gu, J.M.1    Lim, S.O.2    Oh, S.J.3    Yoon, S.M.4    Seong, J.K.5    Jung, G.6
  • 26
    • 57249103576 scopus 로고    scopus 로고
    • Epigenetic changes induced by reactive oxygen species in hepatocellular carcinoma: methylation of the E-cadherin promoter
    • e2121-2128
    • Lim S.O., Gu J.M., Kim M.S., Kim H.S., Park Y.N., Park C.K., Cho J.W., Park Y.M., Jung G. Epigenetic changes induced by reactive oxygen species in hepatocellular carcinoma: methylation of the E-cadherin promoter. Gastroenterology 2008, 135:2128-2140. e2121-2128.
    • (2008) Gastroenterology , vol.135 , pp. 2128-2140
    • Lim, S.O.1    Gu, J.M.2    Kim, M.S.3    Kim, H.S.4    Park, Y.N.5    Park, C.K.6    Cho, J.W.7    Park, Y.M.8    Jung, G.9
  • 27
    • 0032566516 scopus 로고    scopus 로고
    • HBx protein of hepatitis B virus activates Jak1-STAT signaling
    • Lee Y.H., Yun Y. HBx protein of hepatitis B virus activates Jak1-STAT signaling. J. Biol. Chem. 1998, 273:25510-25515.
    • (1998) J. Biol. Chem. , vol.273 , pp. 25510-25515
    • Lee, Y.H.1    Yun, Y.2
  • 28
    • 17444430845 scopus 로고    scopus 로고
    • The transcriptional transactivation function of HBx protein is important for its augmentation role in hepatitis B virus replication
    • Tang H., Delgermaa L., Huang F., Oishi N., Liu L., He F., Zhao L., Murakami S. The transcriptional transactivation function of HBx protein is important for its augmentation role in hepatitis B virus replication. J. Virol. 2005, 79:5548-5556.
    • (2005) J. Virol. , vol.79 , pp. 5548-5556
    • Tang, H.1    Delgermaa, L.2    Huang, F.3    Oishi, N.4    Liu, L.5    He, F.6    Zhao, L.7    Murakami, S.8
  • 29
    • 0034774463 scopus 로고    scopus 로고
    • Mitochondrially associated hepatitis B virus X protein constitutively activates transcription factors STAT-3 and NF-kappa B via oxidative stress
    • Waris G., Huh K.W., Siddiqui A. Mitochondrially associated hepatitis B virus X protein constitutively activates transcription factors STAT-3 and NF-kappa B via oxidative stress. Mol. Cell Biol. 2001, 21:7721-7730.
    • (2001) Mol. Cell Biol. , vol.21 , pp. 7721-7730
    • Waris, G.1    Huh, K.W.2    Siddiqui, A.3
  • 30
    • 0035890060 scopus 로고    scopus 로고
    • Molecular mechanisms of beta-catenin recognition by adenomatous polyposis coli revealed by the structure of an APC-beta-catenin complex
    • Eklof Spink K., Fridman S.G., Weis W.I. Molecular mechanisms of beta-catenin recognition by adenomatous polyposis coli revealed by the structure of an APC-beta-catenin complex. EMBO J. 2001, 20:6203-6212.
    • (2001) EMBO J. , vol.20 , pp. 6203-6212
    • Eklof Spink, K.1    Fridman, S.G.2    Weis, W.I.3
  • 31
    • 19444362674 scopus 로고    scopus 로고
    • The inhibitory mechanism of curcumin and its derivative against beta-catenin/Tcf signaling
    • Park C.H., Hahm E.R., Park S., Kim H.K., Yang C.H. The inhibitory mechanism of curcumin and its derivative against beta-catenin/Tcf signaling. FEBS Lett. 2005, 579:2965-2971.
    • (2005) FEBS Lett. , vol.579 , pp. 2965-2971
    • Park, C.H.1    Hahm, E.R.2    Park, S.3    Kim, H.K.4    Yang, C.H.5
  • 32
    • 33749671337 scopus 로고    scopus 로고
    • Impact of quercetin and EGCG on key elements of the Wnt pathway in human colon carcinoma cells
    • Pahlke G., Ngiewih Y., Kern M., Jakobs S., Marko D., Eisenbrand G. Impact of quercetin and EGCG on key elements of the Wnt pathway in human colon carcinoma cells. J. Agric. Food Chem. 2006, 54:7075-7082.
    • (2006) J. Agric. Food Chem. , vol.54 , pp. 7075-7082
    • Pahlke, G.1    Ngiewih, Y.2    Kern, M.3    Jakobs, S.4    Marko, D.5    Eisenbrand, G.6
  • 34
    • 15744374449 scopus 로고    scopus 로고
    • Wnt-dependent regulation of the E-cadherin repressor snail
    • Yook J.I., Li X.Y., Ota I., Fearon E.R., Weiss S.J. Wnt-dependent regulation of the E-cadherin repressor snail. J. Biol. Chem. 2005, 280:11740-11748.
    • (2005) J. Biol. Chem. , vol.280 , pp. 11740-11748
    • Yook, J.I.1    Li, X.Y.2    Ota, I.3    Fearon, E.R.4    Weiss, S.J.5
  • 35
    • 1442290121 scopus 로고    scopus 로고
    • Hepatitis B virus X protein induces angiogenesis by stabilizing hypoxia-inducible factor-1alpha
    • Moon E.J., Jeong C.H., Jeong J.W., Kim K.R., Yu D.Y., Murakami S., Kim C.W., Kim K.W. Hepatitis B virus X protein induces angiogenesis by stabilizing hypoxia-inducible factor-1alpha. FASEB J. 2004, 18:382-384.
    • (2004) FASEB J. , vol.18 , pp. 382-384
    • Moon, E.J.1    Jeong, C.H.2    Jeong, J.W.3    Kim, K.R.4    Yu, D.Y.5    Murakami, S.6    Kim, C.W.7    Kim, K.W.8
  • 37
    • 33947303068 scopus 로고    scopus 로고
    • Pin1 interacts with a specific serine-proline motif of hepatitis B virus X-protein to enhance hepatocarcinogenesis
    • Pang R., Lee T.K., Poon R.T., Fan S.T., Wong K.B., Kwong Y.L., Tse E. Pin1 interacts with a specific serine-proline motif of hepatitis B virus X-protein to enhance hepatocarcinogenesis. Gastroenterology 2007, 132:1088-1103.
    • (2007) Gastroenterology , vol.132 , pp. 1088-1103
    • Pang, R.1    Lee, T.K.2    Poon, R.T.3    Fan, S.T.4    Wong, K.B.5    Kwong, Y.L.6    Tse, E.7
  • 38
  • 40
    • 0031035764 scopus 로고    scopus 로고
    • The hepatitis B virus X gene potentiates c-myc-induced liver oncogenesis in transgenic mice
    • Terradillos O., Billet O., Renard C.A., Levy R., Molina T., Briand P., Buendia M.A. The hepatitis B virus X gene potentiates c-myc-induced liver oncogenesis in transgenic mice. Oncogene 1997, 14:395-404.
    • (1997) Oncogene , vol.14 , pp. 395-404
    • Terradillos, O.1    Billet, O.2    Renard, C.A.3    Levy, R.4    Molina, T.5    Briand, P.6    Buendia, M.A.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.