Electrical stimulation of the medial forebrain bundle in pre-clinical studies of psychiatric disorders

Neuroscience and Biobehavioral Reviews

Volumn 49, Issue , 2015, Pages 32-42

  Döbrössy, Máté D ^a   Furlanetti, Luciano L ^a   Coenen, Volker A ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Deep brain stimulation; Depression; Electrical stimulation; Medial forebrain bundle; Pre clinical studies; Psychiatric disorders

Indexed keywords

ADDICTION; ANHEDONIA; BRAIN DEPTH STIMULATION; BRAIN FUNCTION; CONNECTOME; DEPRESSION; DISEASE MODEL; ELECTROSTIMULATION; HABENULA; HUMAN; LATERAL HYPOTHALAMUS; MEDIAL FOREBRAIN BUNDLE; MENTAL DISEASE; NEUROANATOMY; NEUROMODULATION; NONHUMAN; NUCLEUS ACCUMBENS; OBSESSIVE COMPULSIVE DISORDER; ORBITAL CORTEX; PREFRONTAL CORTEX; REVIEW; SELF STIMULATION; SUBTHALAMIC NUCLEUS; VENTRAL TEGMENTUM; VENTROMEDIAL PREFRONTAL CORTEX; ANIMAL; MENTAL DISORDERS; PATHOPHYSIOLOGY; PROCEDURES;

ANIMALS; DEEP BRAIN STIMULATION; DISEASE MODELS, ANIMAL; ELECTRIC STIMULATION; MEDIAL FOREBRAIN BUNDLE; MENTAL DISORDERS;

EID: 84918787588     PISSN: 01497634     EISSN: 18737528     Source Type: Journal    
DOI: 10.1016/j.neubiorev.2014.11.018     Document Type: Review

References (136)

1. Alcaro A., Panksepp J. The SEEKING mind: primal neuro-affective substrates for appetitive incentive states and their pathological dynamics in addictions and depression. Neurosci. Biobehav. Rev. 2011, 35:1805-1820. 10.1016/j.neubiorev.2011.03.002.
2. Anand B., Brobeck J. Hypothalamic control of food intake in rats and cats. J. Biol. Med. 1951, 24:123-140.
3. Anderson R.J., Frye M.A., Abulseoud O.A., Lee K.H., McGillivray J.A., Berk M., Tye S.J. Deep brain stimulation for treatment-resistant depression: efficacy, safety and mechanisms of action. Neurosci. Biobehav. Rev. 2012, 36:1920-1933. 10.1016/j.neubiorev.2012.06.001.
4. Barrot M., Sesack S.R., Georges F., Pistis M., Hong S., Jhou T.C. Braking dopamine systems: a new GABA master structure for mesolimbic and nigrostriatal functions. J. Neurosci. Off. J. Soc. Neurosci. 2012, 32:14094-14101. 10.1523/JNEUROSCI.3370-12.2012.
5. Baunez C., Dias C., Cador M., Amalric M. The subthalamic nucleus exerts opposite control on cocaine and "natural" rewards. Nat. Neurosci. 2005, 8:484-489. 10.1038/nn1429.
6. Bewernick B.H., Hurlemann R., Matusch A., Kayser S., Grubert C., Hadrysiewicz B., Axmacher N., Lemke M., Cooper-Mahkorn D., Cohen M.X., Brockmann H., Lenartz D., Sturm V., Schlaepfer T.E. Nucleus accumbens deep brain stimulation decreases ratings of depression and anxiety in treatment-resistant depression. Biol. Psychiatry 2010, 67:110-116. 10.1016/j.biopsych.2009.09.013.
7. Bewernick B.H., Kayser S., Sturm V., Schlaepfer T.E. Long-term effects of nucleus accumbens deep brain stimulation in treatment-resistant depression: evidence for sustained efficacy. Neuropsychopharmacol. Off. Publ. Am. Coll. Neuropsychopharmacol. 2012, 37:1975-1985. 10.1038/npp.2012.44.
8. Björklund A., Dunnett S.B. Dopamine neuron systems in the brain: an update. Trends Neurosci. 2007, 30:194-202. 10.1016/j.tins.2007.03.006.
9. Blood A.J., Iosifescu D.V., Makris N., Perlis R.H., Kennedy D.N., Dougherty D.D., Kim B.W., Lee M.J., Wu S., Lee S., Calhoun J., Hodge S.M., Fava M., Rosen B.R., Smoller J.W., Gasic G.P., Breiter H.C. Microstructural abnormalities in subcortical reward circuitry of subjects with major depressive disorder. PLoS ONE 2010, 5:e13945. Phenotype Genotype Project on Addiction and Mood Disorders. 10.1371/journal.pone.0013945.
10. Bourdy R., Barrot M. A new control center for dopaminergic systems: pulling the VTA by the tail. Trends Neurosci. 2012, 35:681-690. 10.1016/j.tins.2012.06.007.
11. Boureau Y.-L., Dayan P. Opponency revisited: competition and cooperation between dopamine and serotonin. Neuropsychopharmacol. Off. Publ. Am. Coll. Neuropsychopharmacol. 2011, 36:74-97. 10.1038/npp.2010.151.
12. Bürgel U., Mädler B., Honey C.R., Thron A., Gilsbach J., Coenen V.A. Fiber tracking with distinct software tools results in a clear diversity in anatomical fiber tract portrayal. Cent. Eur. Neurosurg. 2009, 70:27-35. 10.1055/s-0028-1087212.
13. Burguière E., Monteiro P., Feng G., Graybiel A.M. Optogenetic stimulation of lateral orbitofronto-striatal pathway suppresses compulsive behaviors. Science 2013, 340:1243-1246. 10.1126/science.1232380.
14. Camilla d'Angelo L.-S., Eagle D.M., Grant J.E., Fineberg N.A., Robbins T.W., Chamberlain S.R. Animal models of obsessive-compulsive spectrum disorders. CNS Spectr. 2013, 1-22. 10.1017/S1092852913000564.
15. Chaudhury D., Walsh J.J., Friedman A.K., Juarez B., Ku S.M., Koo J.W., Ferguson D., Tsai H.-C., Pomeranz L., Christoffel D.J., Nectow A.R., Ekstrand M., Domingos A., Mazei-Robison M.S., Mouzon E., Lobo M.K., Neve R.L., Friedman J.M., Russo S.J., Deisseroth K., Nestler E.J., Han M.-H. Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons. Nature 2013, 493:532-536. 10.1038/nature11713.
16. Chow B.Y., Boyden E.S. Optogenetics and translational medicine. Sci. Transl. Med. 2013, 5:177ps5. 10.1126/scitranslmed.3003101.
17. Coenen V.A., Allert N., Mädler B. A role of diffusion tensor imaging fiber tracking in deep brain stimulation surgery: DBS of the dentato-rubro-thalamic tract (drt) for the treatment of therapy-refractory tremor. Acta Neurochir. (Wien) 2011, 153:1579-1585. discussion 1585. 10.1007/s00701-011-1036-z.
18. Coenen V.A., Mädler B., Schlaepfer T.E. Reply to: Medial forebrain bundle stimulation-speed access to an old or entry into a new depression neurocircuit?. Biol. Psychiatry 2013, 74:43. 10.1016/j.biopsych.2013.06.017.
19. Coenen V.A., Panksepp J., Hurwitz T.A., Urbach H., Mädler B. Human medial forebrain bundle (MFB) and anterior thalamic radiation (ATR): imaging of two major subcortical pathways and the dynamic balance of opposite affects in understanding depression. J. Neuropsychiatry Clin. Neurosci. 2012, 24:223-236. 10.1176/appi.neuropsych.11080180.
20. Coenen V.A., Schlaepfer T.E., Allert N., Mädler B. Diffusion tensor imaging and neuromodulation: DTI as key technology for deep brain stimulation. Int. Rev. Neurobiol. 2012, 107:207-234. 10.1016/B978-0-12-404706-8.00011-5.
21. Coenen V.A., Schlaepfer T.E., Maedler B., Panksepp J. Cross-species affective functions of the medial forebrain bundle-implications for the treatment of affective pain and depression in humans. Neurosci. Biobehav. Rev. 2011, 35:1971-1981. 10.1016/j.neubiorev.2010.12.009.
22. Colonnello V., Iacobucci P., Fuchs T., Newberry R.C., Panksepp J. Octodon degus. A useful animal model for social-affective neuroscience research: basic description of separation distress, social attachments and play. Neurosci. Biobehav. Rev. 2011, 35:1854-1863. 10.1016/j.neubiorev.2011.03.014.
23. Cools R., Nakamura K., Daw N.D. Serotonin and dopamine: unifying affective, activational, and decision functions. Neuropsychopharmacol. Off. Publ. Am. Coll. Neuropsychopharmacol. 2011, 36:98-113. 10.1038/npp.2010.121.
24. Dahlström A., Fuxe K. Evidence for the existence of monoamine-containing neurons in the central nervous system. I. Demonstration of monoamines in the cell bodies of brain stem neurons. Acta Physiol. Scand. Suppl. 1964, 232:1-55.
25. Denys D., Mantione M., Figee M., van den Munckhof P., Koerselman F., Westenberg H., Bosch A., Schuurman R. Deep brain stimulation of the nucleus accumbens for treatment-refractory obsessive-compulsive disorder. Arch. Gen. Psychiatry 2010, 67:1061-1068. 10.1001/archgenpsychiatry.2010.122.
26. Dobi A., Margolis E.B., Wang H.-L., Harvey B.K., Morales M. Glutamatergic and nonglutamatergic neurons of the ventral tegmental area establish local synaptic contacts with dopaminergic and nondopaminergic neurons. J. Neurosci. Off. J. Soc. Neurosci. 2010, 30:218-229. 10.1523/JNEUROSCI.3884-09.2010.
27. Falowski S.M., Sharan A., Reyes B.A.S., Sikkema C., Szot P., Van Bockstaele E.J. An evaluation of neuroplasticity and behavior after deep brain stimulation of the nucleus accumbens in an animal model of depression. Neurosurgery 2011, 69:1281-1290. 10.1227/NEU.0b013e3182237346.
28. Figee M., de Koning P., Klaassen S., Vulink N., Mantione M., van den Munckhof P., Schuurman R., van Wingen G., van Amelsvoort T., Booij J., Denys D. Deep brain stimulation induces striatal dopamine release in obsessive-compulsive disorder. Biol. Psychiatry 2014, 75:647-652. 10.1016/j.biopsych.2013.06.021.
29. Figee M., Luigjes J., Smolders R., Valencia-Alfonso C.-E., van Wingen G., de Kwaasteniet B., Mantione M., Ooms P., de Koning P., Vulink N., Levar N., Droge L., van den Munckhof P., Schuurman P.R., Nederveen A., van den Brink W., Mazaheri A., Vink M., Denys D. Deep brain stimulation restores frontostriatal network activity in obsessive-compulsive disorder. Nat. Neurosci. 2013, 16:386-387. 10.1038/nn.3344.
30. Friedman A., Dremencov E., Crown H., Levy D., Mintz M., Overstreet D.H., Yadid G. Variability of the mesolimbic neuronal activity in a rat model of depression. Neuroreport 2005, 16:513-516.
31. Friedman A., Frankel M., Flaumenhaft Y., Merenlender A., Pinhasov A., Feder Y., Taler M., Gil-Ad I., Abeles M., Yadid G. Programmed acute electrical stimulation of ventral tegmental area alleviates depressive-like behavior. Neuropsychopharmacol. Off. Publ. Am. Coll. Neuropsychopharmacol. 2009, 34:1057-1066. 10.1038/npp.2008.177.
32. Friedman A., Friedman Y., Dremencov E., Yadid G. VTA dopamine neuron bursting is altered in an animal model of depression and corrected by desipramine. J. Mol. Neurosci. 2008, 34:201-209. 10.1007/s12031-007-9016-8.
33. Friedman A., Lax E., Abraham L., Tischler H., Yadid G. Abnormality of VTA local field potential in an animal model of depression was restored by patterned DBS treatment. Eur. Neuropsychopharmacol. J. Eur. Coll. Neuropsychopharmacol. 2012, 22:64-71. 10.1016/j.euroneuro.2011.04.005.
34. Friedman A., Lax E., Dikshtein Y., Abraham L., Flaumenhaft Y., Sudai E., Ben-Tzion M., Ami-Ad L., Yaka R., Yadid G. Electrical stimulation of the lateral habenula produces enduring inhibitory effect on cocaine seeking behavior. Neuropharmacology 2010, 59:452-459. 10.1016/j.neuropharm.2010.06.008.
35. Friedman A., Lax E., Dikshtein Y., Abraham L., Flaumenhaft Y., Sudai E., Ben-Tzion M., Yadid G. Electrical stimulation of the lateral habenula produces an inhibitory effect on sucrose self-administration. Neuropharmacology 2011, 60:381-387. 10.1016/j.neuropharm.2010.10.006.
36. Friedman A., Merenlender A., Lax E., Rosenstein M., Lubin N., Yadid G. Early prediction of the effectiveness of antidepressants: inputs from an animal model. J. Mol. Neurosci. 2009, 39:256-261. 10.1007/s12031-009-9176-9.
37. Geeraedts L.M., Nieuwenhuys R., Veening J.G. Medial forebrain bundle of the rat: IV. Cytoarchitecture of the caudal (lateral hypothalamic) part of the medial forebrain bundle bed nucleus. J. Comp. Neurol. 1990, 294:537-568. 10.1002/cne.902940404.
38. Geeraedts L.M., Nieuwenhuys R., Veening J.G. Medial forebrain bundle of the rat: III. Cytoarchitecture of the rostral (telencephalic) part of the medial forebrain bundle bed nucleus. J. Comp. Neurol. 1990, 294:507-536. 10.1002/cne.902940403.
39. Gersner R., Toth E., Isserles M., Zangen A. Site-specific antidepressant effects of repeated subconvulsive electrical stimulation: potential role of brain-derived neurotrophic factor. Biol. Psychiatry 2010, 67:125-132. 10.1016/j.biopsych.2009.09.015.
40. Greenberg B.D., Gabriels L.A., Malone D.A., Rezai A.R., Friehs G.M., Okun M.S., Shapira N.A., Foote K.D., Cosyns P.R., Kubu C.S., Malloy P.F., Salloway S.P., Giftakis J.E., Rise M.T., Machado A.G., Baker K.B., Stypulkowski P.H., Goodman W.K., Rasmussen S.A., Nuttin B.J. Deep brain stimulation of the ventral internal capsule/ventral striatum for obsessive-compulsive disorder: worldwide experience. Mol. Psychiatry 2010, 15:64-79. 10.1038/mp.2008.55.
41. Gubellini P., Salin P., Kerkerian-Le Goff L., Baunez C. Deep brain stimulation in neurological diseases and experimental models: from molecule to complex behavior. Prog. Neurobiol. 2009, 89:79-123. 10.1016/j.pneurobio.2009.06.003.
42. Hamani C., Amorim B.O., Wheeler A.L., Diwan M., Driesslein K., Covolan L., Butson C.R., Nobrega J.N. Deep brain stimulation in rats: different targets induce similar antidepressant-like effects but influence different circuits. Neurobiol. Dis. 2014, 71:205-214. 10.1016/j.nbd.2014.08.007.
43. Hamani C., Diwan M., Macedo C.E., Brandão M.L., Shumake J., Gonzalez-Lima F., Raymond R., Lozano A.M., Fletcher P.J., Nobrega J.N. Antidepressant-like effects of medial prefrontal cortex deep brain stimulation in rats. Biol. Psychiatry 2010, 67:117-124. 10.1016/j.biopsych.2009.08.025.
44. Hamani C., Machado D.C., Hipólide D.C., Dubiela F.P., Suchecki D., Macedo C.E., Tescarollo F., Martins U., Covolan L., Nobrega J.N. Deep brain stimulation reverses anhedonic-like behavior in a chronic model of depression: role of serotonin and brain derived neurotrophic factor. Biol. Psychiatry 2012, 71:30-35. 10.1016/j.biopsych.2011.08.025.
45. Hamani C., Nóbrega J.N. Deep brain stimulation in clinical trials and animal models of depression. Eur. J. Neurosci. 2010, 32:1109-1117. 10.1111/j.1460-9568.2010.07414.x.
46. Hamani C., Nobrega J.N. Preclinical studies modeling deep brain stimulation for depression. Biol. Psychiatry 2012, 72:916-923. 10.1016/j.biopsych.2012.05.024.
47. Hashemi P., Dankoski E.C., Wood K.M., Ambrose R.E., Wightman R.M. In vivo electrochemical evidence for simultaneous 5-HT and histamine release in the rat substantia nigra pars reticulata following medial forebrain bundle stimulation. J. Neurochem. 2011, 118:749-759. 10.1111/j.1471-4159.2011.07352.x.
48. Hassler R. Motor and sensory effects of circumscribed stimulations and eliminations in the human mesencephalon. Dtsch. Z. Nervenheilkd. 1961, 183:148-171.
49. Hassler R., Riechert T., Mundinger F., Umbach W., Ganglberger J.A. Physiological observations in stereotaxic operations in extrapyramidal motor disturbances. Brain J. Neurol. 1960, 83:337-350.
50. Hikosaka O. The habenula: from stress evasion to value-based decision-making. Nat. Rev. Neurosci. 2010, 11:503-513. 10.1038/nrn2866.
51. Huang F., Tang B., Jiang H. Optogenetic investigation of neuropsychiatric diseases. Int. J. Neurosci. 2012, 10.3109/00207454.2012.728651.
52. Huff W., Lenartz D., Schormann M., Lee S.-H., Kuhn J., Koulousakis A., Mai J., Daumann J., Maarouf M., Klosterkötter J., Sturm V. Unilateral deep brain stimulation of the nucleus accumbens in patients with treatment-resistant obsessive-compulsive disorder: outcomes after one year. Clin. Neurol. Neurosurg. 2010, 112:137-143. 10.1016/j.clineuro.2009.11.006.
53. Ikemoto S. Brain reward circuitry beyond the mesolimbic dopamine system: a neurobiological theory. Neurosci. Biobehav. Rev. 2010, 35:129-150. 10.1016/j.neubiorev.2010.02.001.
54. Ikemoto S., Panksepp J. The role of nucleus accumbens dopamine in motivated behavior: a unifying interpretation with special reference to reward-seeking. Brain Res. Brain Res. Rev. 1999, 31:6-41.
55. Ikemoto S., Wise R.A. Mapping of chemical trigger zones for reward. Neuropharmacology 2004, 47(Suppl. 1):190-201. 10.1016/j.neuropharm.2004.07.012.
56. Koob G.F., Volkow N.D. Neurocircuitry of addiction. Neuropsychopharmacol. Off. Publ. Am. Coll. Neuropsychopharmacol. 2010, 35:217-238. 10.1038/npp.2009.110.
57. Krack P., Hariz M.I., Baunez C., Guridi J., Obeso J.A. Deep brain stimulation: from neurology to psychiatry?. Trends Neurosci. 2010, 33:474-484. 10.1016/j.tins.2010.07.002.
58. Kranz G.S., Kasper S., Lanzenberger R. Reward and the serotonergic system. Neuroscience 2010, 166:1023-1035. 10.1016/j.neuroscience.2010.01.036.
59. Kuhn J., Bührle C.P., Lenartz D., Sturm V. Deep brain stimulation in addiction due to psychoactive substance use. Handb. Clin. Neurol. 2013, 116:259-269. 10.1016/B978-0-444-53497-2.00021-8.
60. LaLumiere R.T. A new technique for controlling the brain: optogenetics and its potential for use in research and the clinic. Brain Stimul. 2011, 4:1-6. 10.1016/j.brs.2010.09.009.
61. Levy D., Shabat-Simon M., Shalev U., Barnea-Ygael N., Cooper A., Zangen A. Repeated electrical stimulation of reward-related brain regions affects cocaine but not "natural" reinforcement. J. Neurosci. Off. J. Soc. Neurosci. 2007, 27:14179-14189. 10.1523/JNEUROSCI.4477-07.2007.
62. Li B., Piriz J., Mirrione M., Chung C., Proulx C.D., Schulz D., Henn F., Malinow R. Synaptic potentiation onto habenula neurons in the learned helplessness model of depression. Nature 2011, 470:535-539. 10.1038/nature09742.
63. Lipsman N., Giacobbe P., Lozano A.M. Deep brain stimulation in obsessive-compulsive disorder: neurocircuitry and clinical experience. Handb. Clin. Neurol. 2013, 116:245-250. 10.1016/B978-0-444-53497-2.00019-X.
64. Liu H.-Y., Jin J., Tang J.-S., Sun W.-X., Jia H., Yang X.-P., Cui J.-M., Wang C.-G. Chronic deep brain stimulation in the rat nucleus accumbens and its effect on morphine reinforcement. Addict. Biol. 2008, 13:40-46. 10.1111/j.1369-1600.2007.00088.x.
65. Lobo M.K., Nestler E.J., Covington H.E. Potential utility of optogenetics in the study of depression. Biol. Psychiatry 2012, 71:1068-1074. 10.1016/j.biopsych.2011.12.026.
66. Lozano A.M., Giacobbe P., Hamani C., Rizvi S.J., Kennedy S.H., Kolivakis T.T., Debonnel G., Sadikot A.F., Lam R.W., Howard A.K., Ilcewicz-Klimek M., Honey C.R., Mayberg H.S. A multicenter pilot study of subcallosal cingulate area deep brain stimulation for treatment-resistant depression. J. Neurosurg. 2012, 116:315-322. 10.3171/2011.10.JNS102122.
67. Lu L., Grimm J.W., Shaham Y., Hope B.T. Molecular neuroadaptations in the accumbens and ventral tegmental area during the first 90 days of forced abstinence from cocaine self-administration in rats. J. Neurochem. 2003, 85:1604-1613.
68. Mallet L., Polosan M., Jaafari N., Baup N., Welter M.-L., Fontaine D., du Montcel S.T., Yelnik J., Chéreau I., Arbus C., Raoul S., Aouizerate B., Damier P., Chabardès S., Czernecki V., Ardouin C., Krebs M.-O., Bardinet E., Chaynes P., Burbaud P., Cornu P., Derost P., Bougerol T., Bataille B., Mattei V., Dormont D., Devaux B., Vérin M., Houeto J.-L., Pollak P., Benabid A.-L., Agid Y., Krack P., Millet B., Pelissolo A. Subthalamic nucleus stimulation in severe obsessive-compulsive disorder. N. Engl. J. Med. 2008, 359:2121-2134. STOC Study Group. 10.1056/NEJMoa0708514.
69. Malone D.A., Dougherty D.D., Rezai A.R., Carpenter L.L., Friehs G.M., Eskandar E.N., Rauch S.L., Rasmussen S.A., Machado A.G., Kubu C.S., Tyrka A.R., Price L.H., Stypulkowski P.H., Giftakis J.E., Rise M.T., Malloy P.F., Salloway S.P., Greenberg B.D. Deep brain stimulation of the ventral capsule/ventral striatum for treatment-resistant depression. Biol. Psychiatry 2009, 65:267-275. 10.1016/j.biopsych.2008.08.029.
70. Martin-Soelch C. Is depression associated with dysfunction of the central reward system?. Biochem. Soc. Trans. 2009, 37:313-317. 10.1042/BST0370313.
71. Mayberg H.S. Limbic-cortical dysregulation: a proposed model of depression. J. Neuropsychiatry Clin. Neurosci. 1997, 9:471-481.
72. Mayberg H.S. Targeted electrode-based modulation of neural circuits for depression. J. Clin. Invest. 2009, 119:717-725. 10.1172/JCI38454.
73. Mayberg H.S., Brannan S.K., Tekell J.L., Silva J.A., Mahurin R.K., McGinnis S., Jerabek P.A. Regional metabolic effects of fluoxetine in major depression: serial changes and relationship to clinical response. Biol. Psychiatry 2000, 48:830-843.
74. McCracken C.B., Grace A.A. High-frequency deep brain stimulation of the nucleus accumbens region suppresses neuronal activity and selectively modulates afferent drive in rat orbitofrontal cortex in vivo. J. Neurosci. Off. J. Soc. Neurosci. 2007, 27:12601-12610. 10.1523/JNEUROSCI.3750-07.2007.
75. McCracken C.B., Grace A.A. Nucleus accumbens deep brain stimulation produces region-specific alterations in local field potential oscillations and evoked responses in vivo. J. Neurosci. Off. J. Soc. Neurosci. 2009, 29:5354-5363. 10.1523/JNEUROSCI.0131-09.2009.
76. Meng H., Wang Y., Huang M., Lin W., Wang S., Zhang B. Chronic deep brain stimulation of the lateral habenula nucleus in a rat model of depression. Brain Res. 2011, 1422:32-38. 10.1016/j.brainres.2011.08.041.
77. Miocinovic S., Somayajula S., Chitnis S., Vitek J.L. History, applications, and mechanisms of deep brain stimulation. JAMA Neurol. 2013, 70:163-171. 10.1001/2013.jamaneurol.45.
78. Munckhof P.V.D., Bosch D., Mantione M., Figee M., Denys D., Schuurman P. Active stimulation site of nucleus accumbens DBS in OCD is localized in the Ventral Internal Capsule. Stereotactic and Functional Neurosurgery 2013, Springer, Vienna. G. Nikkhah, M. Pinsker (Eds.).
79. Nakamura K. The role of the dorsal raphé nucleus in reward-seeking behavior. Front. Integr. Neurosci. 2013, 7:60. 10.3389/fnint.2013.00060.
80. Nangunoori R., Tomycz N.D., Quigley M., Oh M.Y., Whiting D.M. Deep brain stimulation for psychiatric diseases: a pooled analysis of published studies employing disease-specific standardized outcome scales. Stereotact. Funct. Neurosurg. 2013, 91:345-354. 10.1159/000351156.
81. Nestler E.J., Barrot M., DiLeone R.J., Eisch A.J., Gold S.J., Monteggia L.M. Neurobiology of depression. Neuron 2002, 34:13-25.
82. Nestler E.J., Carlezon W.A. The mesolimbic dopamine reward circuit in depression. Biol. Psychiatry 2006, 59:1151-1159. 10.1016/j.biopsych.2005.09.018.
83. Nestler E.J., Gould E., Manji H. Preclinical models: status of basic research in depression. Biol. Psychiatry 2002, 52:503-528. 10.1016/S0006-3223(02)01405-1.
84. Neumann I.D., Wegener G., Homberg J.R., Cohen H., Slattery D.A., Zohar J., Olivier J.D.A., Mathé A.A. Animal models of depression and anxiety: what do they tell us about human condition?. Prog. Neuropsychopharmacol. Biol. Psychiatry 2011, 35:1357-1375. 10.1016/j.pnpbp.2010.11.028.
85. Nieuwenhuys R., Geeraedts L.M., Veening J.G. The medial forebrain bundle of the rat. I. General introduction. J. Comp. Neurol. 1982, 206:49-81. 10.1002/cne.902060106.
86. Nuttin B., Cosyns P., Demeulemeester H., Gybels J., Meyerson B. Electrical stimulation in anterior limbs of internal capsules in patients with obsessive-compulsive disorder. Lancet 1999, 354:1526. 10.1016/S0140-6736(99)02376-4.
87. Olds J. Self-stimulation experiments. Science 1963, 140:218-220.
88. Olds J., Milner P. Positive reinforcement produced by electrical stimulation of the septal area and other regions of rat brain. J. Comp. Physiol. Psychol. 1954, 419-427.
89. Overstreet D.H. Modeling depression in animal models. Methods Mol. Biol. 2012, 829:125-144. 10.1007/978-1-61779-458-2_7.
90. Overstreet D.H., Wegener G. The flinders sensitive line rat model of depression - 25 years and still producing. Pharmacol. Rev. 2013, 65:143-155. 10.1124/pr.111.005397.
91. Panksepp J. Affective Neuroscience: The Foundations of Human and Animal Emotions 1998, Oxford University Press, New York.
92. Panksepp J. Affective neuroscience of the emotional BrainMind: evolutionary perspectives and implications for understanding depression. Dialogues Clin. Neurosci. 2010, 12:533-545.
93. Panksepp J. The basic emotional circuits of mammalian brains: do animals have affective lives?. Neurosci. Biobehav. Rev. 2011, 35:1791-1804. 10.1016/j.neubiorev.2011.08.003.
94. Panksepp J.B., Lahvis G.P. Rodent empathy and affective neuroscience. Neurosci. Biobehav. Rev. 2011, 35:1864-1875. 10.1016/j.neubiorev.2011.05.013.
95. Pauls D.L., Abramovitch A., Rauch S.L., Geller D.A. Obsessive-compulsive disorder: an integrative genetic and neurobiological perspective. Nat. Rev. Neurosci. 2014, 15:410-424. 10.1038/nrn3746.
96. Pierce R.C., Vassoler F.M. Deep brain stimulation for the treatment of addiction: basic and clinical studies and potential mechanisms of action. Psychopharmacology (Berl.) 2013, 229:487-491. 10.1007/s00213-013-3214-6.
97. Price J.L., Drevets W.C. Neural circuits underlying the pathophysiology of mood disorders. Trends Cogn. Sci. 2012, 16:61-71. 10.1016/j.tics.2011.12.011.
98. Rea E., Rummel J., Schmidt T.T., Hadar R., Heinz A., Mathé A.A., Winter C. Anti-anhedonic effect of deep brain stimulation of the prefrontal cortex and the dopaminergic reward system in a genetic rat model of depression: an intracranial self-stimulation paradigm study. Brain Stimul. 2013, 10.1016/j.brs.2013.09.002.
99. Roeper J. Dissecting the diversity of midbrain dopamine neurons. Trends Neurosci. 2013, 36:336-342. 10.1016/j.tins.2013.03.003.
100. Rouaud T., Lardeux S., Panayotis N., Paleressompoulle D., Cador M., Baunez C. Reducing the desire for cocaine with subthalamic nucleus deep brain stimulation. Proc. Natl. Acad. Sci. U. S. A. 2010, 107:1196-1200. 10.1073/pnas.0908189107.
101. Routtenberg A. "Self-starvation" of rats living in activity wheels: adaptation effects. J. Comp. Physiol. Psychol. 1968, 66:234-238.
102. Routtenberg A., Kuznesof A.W. Self-starvation of rats living in activity wheels on a restricted feeding schedule. J. Comp. Physiol. Psychol. 1967, 64:414-421.
103. Routtenberg A., Lindy J. Effects of the availability of rewarding septal and hypothalamic stimulation on bar pressing for food under conditions of deprivation. J. Comp. Physiol. Psychol. 1965, 60:158-161.
104. Russo S.J., Nestler E.J. The brain reward circuitry in mood disorders. Nat. Rev. Neurosci. 2013, 14:609-625. 10.1038/nrn3381.
105. Schlaepfer T.E., Bewernick B.H., Kayser S., Hurlemann R., Coenen V.A. Deep brain stimulation of the human reward system for major depression - rationale, outcomes and outlook. Neuropsychopharmacol. Off. Publ. Am. Coll. Neuropsychopharmacol. 2014, 39:1303-1314. 10.1038/npp.2014.28.
106. Schlaepfer T.E., Bewernick B.H., Kayser S., Mädler B., Coenen V.A. Rapid effects of deep brain stimulation for treatment-resistant major depression. Biol. Psychiatry 2013, 73:1204-1212. 10.1016/j.biopsych.2013.01.034.
107. Schlaepfer T.E., Bewernick B., Kayser S., Lenz D. Modulating affect, cognition, and behavior - prospects of deep brain stimulation for treatment-resistant psychiatric disorders. Front. Integr. Neurosci. 2011, 5:29. 10.3389/fnint.2011.00029.
108. Schlaepfer T.E., Cohen M.X., Frick C., Kosel M., Brodesser D., Axmacher N., Joe A.Y., Kreft M., Lenartz D., Sturm V. Deep brain stimulation to reward circuitry alleviates anhedonia in refractory major depression. Neuropsychopharmacol. Off. Publ. Am. Coll. Neuropsychopharmacol. 2008, 33:368-377. 10.1038/sj.npp.1301408.
109. Schlaepfer T.E., George M.S., Mayberg H. WFSBP guidelines on brain stimulation treatments in psychiatry. World J. Biol. Psychiatry Off. J. World Fed. Soc. Biol. Psychiatry 2010, 11:2-18. WFSBP Task Force on Brain Stimulation. 10.3109/15622970903170835.
110. Schlaepfer T.E., Lieb K. Deep brain stimulation for treatment of refractory depression. Lancet 2005, 366:1420-1422. 10.1016/S0140-6736(05)67582-4.
111. Schmuckermair C., Gaburro S., Sah A., Landgraf R., Sartori S.B., Singewald N. Behavioral and neurobiological effects of deep brain stimulation in a mouse model of high anxiety- and depression-like behavior. Neuropsychopharmacol. Off. Publ. Am. Coll. Neuropsychopharmacol. 2013, 38:1234-1244. 10.1038/npp.2013.21.
112. Schultz W. Behavioral dopamine signals. Trends Neurosci. 2007, 30:203-210. 10.1016/j.tins.2007.03.007.
113. Schultz W. Updating dopamine reward signals. Curr. Opin. Neurobiol. 2013, 23:229-238. 10.1016/j.conb.2012.11.012.
114. Spiegel E.A., Wycis H.T. Thalamotomy and pallidotomy for treatment of choreic movements. Acta Neurochir. (Wien) 1952, 2:417-422.
115. Spiegel E.A., Wycis H.T., Marks M., Lee A.J. Stereotaxic apparatus for operations on the human brain. Science 1947, 106:349-350. 10.1126/science.106.2754.349.
116. Swedo S.E., Schapiro M.B., Grady C.L., Cheslow D.L., Leonard H.L., Kumar A., Friedland R., Rapoport S.I., Rapoport J.L. Cerebral glucose metabolism in childhood-onset obsessive-compulsive disorder. Arch. Gen. Psychiatry 1989, 46:518-523.
117. Tan S.K., Vlamings R., Lim L., Sesia T., Janssen M.L., Steinbusch H.W., Visser-Vandewalle V., Temel Y. Experimental deep brain stimulation in animal models. Neurosurgery 2010, 67:1073-1079. discussion 1080. 10.1227/NEU.0b013e3181ee3580.
118. Teitelbaum P., Epstein A. The lateral hypothalamic syndrome: recovery of feeding and drinking after lateral hypothalamic lesions. Psychol. Rev. 1962, 69:74-90.
119. Teitelbaum P., Stellar E. Recovery from the failure to eat produced by hypothalamic lesions. Science 1954, 120:894-895.
120. Temel Y., Boothman L.J., Blokland A., Magill P.J., Steinbusch H.W.M., Visser-Vandewalle V., Sharp T. Inhibition of 5-HT neuron activity and induction of depressive-like behavior by high-frequency stimulation of the subthalamic nucleus. Proc. Natl. Acad. Sci. U. S. A. 2007, 104:17087-17092. 10.1073/pnas.0704144104.
121. Tye K.M., Mirzabekov J.J., Warden M.R., Ferenczi E.A., Tsai H.-C., Finkelstein J., Kim S.-Y., Adhikari A., Thompson K.R., Andalman A.S., Gunaydin L.A., Witten I.B., Deisseroth K. Dopamine neurons modulate neural encoding and expression of depression-related behaviour. Nature 2013, 493:537-541. 10.1038/nature11740.
122. Ungerstedt U. Is interruption of the nigro-striatal dopamine system producing the "lateral hypothalamus syndrome"?. Acta Physiol. Scand. 1970, 80:35A-36A. 10.1111/j.1748-1716.1970.tb04858.x.
123. Van Laere K., Nuttin B., Gabriels L., Dupont P., Rasmussen S., Greenberg B.D., Cosyns P. Metabolic imaging of anterior capsular stimulation in refractory obsessive-compulsive disorder: a key role for the subgenual anterior cingulate and ventral striatum. J. Nucl. Med. Off. Publ. Soc. Nucl. Med. 2006, 47:740-747.
124. Vassoler F.M., Schmidt H.D., Gerard M.E., Famous K.R., Ciraulo D.A., Kornetsky C., Knapp C.M., Pierce R.C. Deep brain stimulation of the nucleus accumbens shell attenuates cocaine priming-induced reinstatement of drug seeking in rats. J. Neurosci. Off. J. Soc. Neurosci. 2008, 28:8735-8739. 10.1523/JNEUROSCI.5277-07.2008.
125. Vassoler F.M., White S.L., Hopkins T.J., Guercio L.A., Espallergues J., Berton O., Schmidt H.D., Pierce R.C. Deep brain stimulation of the nucleus accumbens shell attenuates cocaine reinstatement through local and antidromic activation. J. Neurosci. Off. J. Soc. Neurosci. 2013, 33:14446-14454. 10.1523/JNEUROSCI.4804-12.2013.
126. Veening J.G., Swanson L.W., Cowan W.M., Nieuwenhuys R., Geeraedts L.M. The medial forebrain bundle of the rat. II. An autoradiographic study of the topography of the major descending and ascending components. J. Comp. Neurol. 1982, 206:82-108. 10.1002/cne.902060107.
127. Veerakumar A., Challis C., Gupta P., Da J., Upadhyay A., Beck S.G., Berton O. Antidepressant-like effects of cortical deep brain stimulation coincide with pro-neuroplastic adaptations of serotonin systems. Biol. Psychiatry 2014, 76:203-212. 10.1016/j.biopsych.2013.12.009.
128. Voges J., Müller U., Bogerts B., Münte T., Heinze H.-J. Deep brain stimulation surgery for alcohol addiction. World Neurosurg. 2013, 80. S28.e21-e31. 10.1016/j.wneu.2012.07.011.
129. Winter C., Vollmayr B., Djodari-Irani A., Klein J., Sartorius A. Pharmacological inhibition of the lateral habenula improves depressive-like behavior in an animal model of treatment resistant depression. Behav. Brain Res. 2011, 216:463-465. 10.1016/j.bbr.2010.07.034.
130. Wise R.A. Addictive drugs and brain stimulation reward. Annu. Rev. Neurosci. 1996, 19:319-340. 10.1146/annurev.ne.19.030196.001535.
131. Wise R.A. Neurobiology of addiction. Curr. Opin. Neurobiol. 1996, 6:243-251.
132. Wise R.A. Brain reward circuitry: insights from unsensed incentives. Neuron 2002, 36:229-240.
133. Witjas T., Baunez C., Henry J.M., Delfini M., Regis J., Cherif A.A., Peragut J.C., Azulay J.P. Addiction in Parkinson's disease: impact of subthalamic nucleus deep brain stimulation. Mov. Disord. Off. J. Mov. Disord. Soc. 2005, 20:1052-1055. 10.1002/mds.20501.
134. Witjas T., Eusebio A., Fluchère F., Azulay J.-P. Addictive behaviors and Parkinson's disease. Rev. Neurol. (Paris) 2012, 168:624-633. 10.1016/j.neurol.2012.06.014.
135. Witten I.B., Steinberg E.E., Lee S.Y., Davidson T.J., Zalocusky K.A., Brodsky M., Yizhar O., Cho S.L., Gong S., Ramakrishnan C., Stuber G.D., Tye K.M., Janak P.H., Deisseroth K. Recombinase-driver rat lines: tools, techniques, and optogenetic application to dopamine-mediated reinforcement. Neuron 2011, 72:721-733. 10.1016/j.neuron.2011.10.028.
136. Yan N., Chen N., Zhu H., Zhang J., Sim M., Ma Y., Wang W. High-frequency stimulation of nucleus accumbens changes in dopaminergic reward circuit. PLOS ONE 2013, 8:e79318. 10.1371/journal.pone.0079318.