Affective neuroscience of the emotional Brain Mind: Evolutionary perspectives and implications for understanding depression;Neurociencias afectivas del cerebro emocional: Perspectivas evolutivas y sus consecuencias para comprender la depresión

Dialogues in Clinical Neuroscience

Volumn 12, Issue 4, 2010, Pages 533-545

  Panksepp, Jaak ^a  

^a College of Veterinary Medicine ^*  (United States)

Author keywords

Affect; Affective neuroscience; Depression; Emotion; Endophenotype; Grief; Play; Seeking

Indexed keywords

ANGER; ANXIETY; ARTICLE; COGNITION; DEPRESSION; DISTRESS SYNDROME; EMOTION; FEAR; GENITAL SYSTEM; HEALTH BELIEF; LEARNING; NONHUMAN; NURTURING BEHAVIOR; RAGE; SURVIVAL RATE; ANIMAL; BIOLOGICAL MODEL; BRAIN; DISEASE MODEL; EVOLUTION; HUMAN; NEUROSCIENCE; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PSYCHOLOGICAL ASPECT;

ANIMALS; BIOLOGICAL EVOLUTION; BRAIN; DEPRESSION; DISEASE MODELS, ANIMAL; EMOTIONS; HUMANS; MODELS, BIOLOGICAL; NEUROSCIENCES;

EID: 79952468204     PISSN: 12948322     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (63)

1. Kassel JD, ed. Substance Abuse and Emotion. Washington, DC: American Psychological Association; 2010; see in particular 137-168.
2. Khantzian EJ. Understanding addictive vulnerability: an evolving psychodynamic perspective. (with commentaries by Johnson B, Koob GF, Morrison V, Panksepp J, Yorke C, and response by Khantzian EJ). Neuropsychoanalysis. 2003;5:5-56.
3. Panksepp, J. Affective Neuroscience: the Foundations of Human and Animal Emotion. New York, NY: Oxford University Press; 1998.
4. MacLean P. The Triune Brain in Evolution. New York, NY: Plenum Press; 1990.
5. Panksepp J. The affective brain and core-consciousness: how does neural activity generate emotional feelings? In Lewis M, Haviland JM, Barrett LF, eds. Handbook of Emotions. New York, NY: Guilford; 2008:47-67.
6. Panksepp J. At the interface between the affective, behavioral and cognitive neurosciences: decoding the emotional feelings of the brain. Brain Cogn. 2003;52:4-14.
7. The Anxious Brain. Available at: http://www.charlierose.com/view/interview/11028?sponsor_id=1. Accessed October 2010.
8. Liotti M, Panksepp J. On the neural nature of human emotions and implications for biological psychiatry. In Panksepp J, ed. Textbook of Biological Psychiatry. Hoboken, NJ: Wiley; 2004:33-74.
9. Panksepp J. Affective consciousness: core emotional feelings in animals and humans. Conscious Cogn. 2005;14:19-69.
10. Panksepp J. Emotional endophenotypes in evolutionary psychiatry. Progr Neuro-Psychopharmacol BioPsychiatry. 2006;30:774-784.
11. Hyman SE. Can neuroscience be integrated into the DSM-V? Nat Rev Neurosci. 2007;8:725-732.
12. Meaney MJ. Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations. Ann Rev Neurosci. 2001;24:161-1192.
13. Russell JA. Core affect and the psychological construction of emotion. Psychol Rev. 2003;110:145-172.
14. Panksepp J. Mood changes: In Vinken PJ, Bruyn GW, Klawans HL, eds. Handbook of Clinical Neurology (Revised series). Vol 1(45). Clinical Neuropsychology. Amsterdam, the Netherlands: Elsevier Science Publishers; 1985:271-285.
15. Cannon WB. The James-Lange theory of emotions: a critical examination and an alternative theory. Am J Psychol. 1927;39:106-124.
16. Panksepp J, Normansell LA, Cox JF, Siviy S. Effects of neonatal decortication on the social play of juvenile rats. Physiol Behav. 1994;56:429-443.
17. Panksepp J. The periconscious substrates of consciousness: Affective states and the evolutionary origins of the SELF. J Conscious Stud. 1998;5:566-582.
18. Northoff G. Psychopathology and pathophysiology of the self in depression neuropsychiatric hypothesis. J Affect Disord. 2007;104:1-14.
19. Damasio AR, Grabowski TJ, Bechara A, et al. Sub-neocortical and cortical brain activity during the feeling of self-generated emotions. Nat Neurosci. 2000;3:1049-1056.
20. Panksepp J. Aggression elicited by electrical stimulation of the hypothalamus in albino rats. Physiol Behav. 1971;6;311-316.
21. Burgdorf J, Wood PL, Kroes RA, Moskal JR, Panksepp J. Neurobiology of 50-kHz ultrasonic vocalizations in rats: Electrode mapping, lesion, and pharmacology studies. Behav Brain Res. 2007;182:274-283.
22. Panksepp, J. On the embodied neural nature of core emotional affects. J Conscious Stud. 2005;12:158-184.
23. Panksepp J. Brain opioids: a neurochemical substrate for narcotic and social dependence. In: Cooper S, ed. Progress in Theory in Psychopharmacology. London, UK: Academic Press, 1981:149-175.
24. Panksepp J. Biven, L. Archaeology of Mind. New York, NY: Norton, 2011.
25. Alcaro A, Huber R, Panksepp, J. Behavioral functions of the mesolimbic dopaminergic system: an affective neuroethological perspective. Brain Res Rev. 2007;56:283-321.
26. Siegel A. The Neurobiology of Aggression and Rage. Boca Raton, FL; CRC Press; 2005.
27. Panksepp J, Fuchs, T, Iacbucci, P. The basic neuroscience of emotional experiences in mammals: the case of subcortical FEAR circuitry and implications for clinical anxiety. Applied Animal Behav Sci. 2010. In press.
28. Pfaff DW. Drive: Neurobiological and Molecular Mechanisms of Sexual Behavior. Cambridge, MA: MIT Press; 1999.
29. Numan M, Insel TR. The Neurobiology of Maternal Behavior. New York: Springer; 2003.
30. Panksepp J. The neurobiology of social loss in animals: some keys to the puzzle of psychic pain in humans. In. Jensen-Campbell LA, MacDonald G, eds. Social Pain: Neuropsychological and Health Implications of Loss and Exclusion. American Psychological Association, Washington, DC. 2010:11-52.
31. Pellis S, Pellis V. The Playful Brain: Venturing to the Limits of Neuroscience. Oxford, UK: One World: 2009.
32. Burgdorf J, Kroes RA, Beinfeld MC, Panksepp J, Moskal JR. Uncovering the molecular basis of positive affect using rough-and-tumble play in rats: a role for insulin-like growth factor I. Neuroscience. 2010;168:769-777.
33. Bowlby J. Attachment and Loss, Vol. 3. Loss: Sadness and Depression. London, UK: Hogarth Press; 1980.
34. Watt DF, Panksepp J. Depression: an evolutionarily conserved mechanism to terminate separation-distress? A review of aminergic, peptidergic, and neural network perspectives. (with commentaries) Neuropsychoanalysis. 2009;11:5-104.
35. McEwen BS. Physiology and neurobiology of stress and adaptation: central role of the brain. Physiol Rev. 2007;87:873-904.
36. Harro J, Oreland L. Depression as a spreading adjustment disorder of monoaminergic neurons: A case for primary implications of the locus coeruleus. Brain Res Rev. 2001;38:79-128.
37. Heim C, Nemeroff CB. The impact of early adverse experiences on brain systems involved in the patho-physiology of anxiety and affective disorders. Biol Psychiatry. 1999;46:1509-1522.
38. Mayberg HS, Lozano AM, Voon V, et al. Deep brain stimulation for treatment-resistant depression. Neuron. 2005;45:651-660.
39. Schlaepfer TE, Cohen MX, Frick C, et al. Deep brain stimulation to reward circuitry alleviates anhedonia in refractory major depression. Neuropsychopharmacology. 2008;33:368-377.
40. Herman BH, Panksepp J. Ascending endorphinergic inhibition of distress vocalization. Science, 1981;211:1060-1062.
41. Panksepp J. Feeling the pain of social loss. Science, 2003;302:237-239.
42. Panksepp J, Herman B, Conner R, Bishop P, Scott, JP. The biology of social attachments: opiates alleviate separation distress. Biol Psychiatry. 1978;13:607-618.
43. Bodkin JA, Zornberg GL, Lukas SE, Cole JO. Buprenorphine treatment of refractory depression. J Clin Psychopharmacol. 1995;15:49-57.
44. Holsboer F. The role of peptides in treatment of psychiatric disorders. J Neural Transm. 2003;64(suppl):17-34.
45. Zarate, CA. Singh JB, Carlson PJ, et al. A randomized trial of an Nmethyl-D-aspartate antagonist in treatmentresistant major depression. Arch Gen Psychiatry, 2006;63:856-864.
46. Anisman H, Merali Z, Hayley S. Neurotransmitter, peptide and cytokine processes in relation to depressive disorder: Comorbidity between depression and neurodegenerative disorders. Progr Neurobiol. 2008;85;1-74.
47. Nestler EJ, Carlezon WA Jr. The mesolimbic dopamine reward circuit in depression. Biol Psychiatry. 2006;59:1151-1159.
48. McLaughlin JP, Marton-Popovici M, Chavkin C. Kappa opioid receptor antagonism and prodynorphin gene disruption block stress-induced behavioral responses. J Neurosci. 2003;23:5674-5683.
49. Panksepp J. Can PLAY diminish ADHD and facilitate the construction of the social brain. J Can Acad Child Adolesc Psychiatry. 2007;10:57-66.
50. Gordon NS, Burke S, Akil H, Watson J. Panksepp J. Socially induced brain fertilization: play promotes brain derived neurotrophic factor expression. Neurosci Lett. 2003;341:17-20.
51. Panksepp J., Harro, J. The future of neuropeptides in biological psychiatry and emotional psychopharmacology: goals and strategies. In. Panksepp J, ed. Textbook of Biological Psychiatry. Hoboken, NJ: Wiley, 2004:627-660.
52. Davis KL, Panksepp J, Normansell L. The affective neuroscience personality scales: Normative data and implications. Neuropsychoanalysis. 2003;5:21-29.
53. Knutson B, Burgdorf J, Panksepp J. Ultrasonic vocalizations as indices of affective states in rat. Psychol Bull. 2002;128:961-977.
54. Panksepp, J, Knutson, B, Burgdorf, J. The role of emotional brain systems in addictions: a neuro-evolutionary perspective. Addiction. 2002;97:459-469.
55. Panksepp J, Zellner M. Towards a neurobiologically based unified theory of aggression. Rev Int Psychol Sociale/Int Rev Soc Psychol. 2004;17:37-61.
56. Panksepp J. Evolutionary substrates of addiction: the neurochemistries of pleasure seeking and social bonding in the mammalian brain. In. Kassel JD, ed. Substance Abuse and Emotion. Washington, DC: American Psychological Association; 2010:137-168.
57. Panksepp J, Nocjar C, Burgdorf J, Panksepp JB, Huber R. The role of emotional systems in addiction: a neuroethological perspective. In: Bevins RA, Bardo MT, eds. 50th Nebraska Symposium on Motivation: Motivational Factors in the Etiology of Drug Abuse. Lincoln: Nebraska; 2004:85-126.
58. Panksepp J, Watt DW. Why does depression hurt? Ancestral primaryprocess separation-distress (PANIC/GRIEF) and diminished brain reward (SEEKING) processes in the genesis of depressive affect. Psych Interpers Biol Proc. 2011. In press.
59. Schoene-Bake J-C, Parpaley Y, Weber B, Panksepp J, Hurwitz TA, Coenen VA. Tractographic analysis of historical lesion-surgery for depression, Neuropsychopharmacology. 2010;35:2553-2563.
60. Zellner M, Solms M, Watt DW, Panksepp J. Affective neuroscientific and neuropsychoanalytic approaches to two intractable psychiatric problems: why depression feels so bad and what addicts really want. Neurosci Biobehav Rev. 2011. In press.
61. Burgdorf J, Panksepp J, Brudzynski SM, Moskal JR. Breeding for 50-kHz positive affective vocalizations in rats. Behavior Genetics. 2005;35:67-72.
62. Burgdorf J, Panksepp J, Brudzynski SM, et al. The effects of selective breeding for differential rates of 50-kHz ultrasonic vocalizations on emotional behavior in rats. Dev Psychobiol. 2008;51:34-46.
63. Krishnan V, Han MH, Graham DL, et al. Molecular adaptations underlying susceptibility and resistance to social defeat in brain reward regions. Cell. 2007;131:691-700.