A chemically defined trifunctional antibody-cytokine-drug conjugate with potent antitumor activity

Molecular Cancer Therapeutics

Volumn 13, Issue 11, 2014, Pages 2641-2652

  List, Thomas ^a   Casi, Giulio ^b   Neri, Dario ^a  

^a ETH ZURICH   (Switzerland)

^b PHILOCHEM AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY CONJUGATE; CANCER ANTIBODY; CYTOTOXIC AGENT; F8 ANTIBODY INTERLEUKIN 2 DISULFIDE LINKED DM1 IMMUNOCYTOKINE; FIBRONECTIN; INTERLEUKIN 2; UNCLASSIFIED DRUG; ANTIBODY; CYTOKINE; IMMUNOTOXIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN BINDING; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER SIZE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG CONJUGATION; EMBRYONAL CARCINOMA STEM CELL; IN VITRO STUDY; KIDNEY CLEARANCE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; ANIMAL; CHEMISTRY; CHO CELL LINE; CRICETULUS; DISEASE MODEL; FEMALE; HAMSTER; HUMAN; IMMUNOLOGY; MALE; NEOPLASMS; TUMOR CELL LINE;

ANIMALS; ANTIBODIES; CELL LINE, TUMOR; CHO CELLS; CRICETINAE; CRICETULUS; CYTOKINES; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; IMMUNOTOXINS; MALE; MICE; NEOPLASMS;

EID: 84918786411     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-14-0599     Document Type: Article

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